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The map label for this gene is atsA [H]

Identifier: 103485794

GI number: 103485794

Start: 297402

End: 299231

Strand: Direct

Name: atsA [H]

Synonym: Sala_0299

Alternate gene names: 103485794

Gene position: 297402-299231 (Clockwise)

Preceding gene: 103485793

Following gene: 103485797

Centisome position: 8.89

GC content: 67.49

Gene sequence:

>1830_bases
ATGGCAGCAGGCTGGAGGACCACCAGGCGGGGCCGGACAGGTGCGTCCCGGCGTGCTGCCATCATCGCGCTCGCATGCCT
GTTGGGAAGCACATCGGGCCTGGCGCAGTCACGCGCGGCGCCGCCGCGCCAGCCCAATATCGTCATCCTGCTCGCCGACG
ACTGGGGGTTTTCGGACGTCGGTGCCTTTGGCTCCGAAATCGCGACACCGCATATCGACGCGCTCGCACGCGCCGGAATG
CGCTTTGCGAACTTCCATGTCTCGGGTTCCTGCTCGCCGACGCGCGCGATGCTCCAGACGGGGGTGATGAACCACCGCAA
CGGCCTCGGCAACATGCCCGAGACGATCCCCGACGAACATCGCGGCAAGCCCGGTTACGACACGGTGATGAACCTGCGCG
TCGTGACGATCGCAGAGTTGATGAAGGCCGCGGGATACCGCACCTACCTGACCGGCAAATGGCATCTGGGCAGCGACGCA
AAGCGGCTGCCCGAAGCGCGCGGATACGACCGCGCCTTCAGTCTCGCCGATGCGGGCGCCGACAATTTCGAGCAGCGACC
GATCGAAGGGCTGTACGACAAGGCGAACTGGACCGAGAACGGCCGCCCCGCGACCCTGCCCCGCGATTATTATTCATCCA
CCTTCGTCGTCGAAAAGATGATCGAATATATCGAGGCGGATCGCGATAGCGGCAAACCCTTCCTCGCCTCGATCAACTTC
CTCGCCAATCATATCCCGGTGCAGGCGCCCGACAGCGACATCGCGCGCTATGCGGCGATGTATCAGGACGGCTGGACGGC
GCTGCGCGAGGCACGCGCGCGGCGTGCGGCGGCACTCGGCATCGTGCCGGCGGGCACGCCGATGGTGACGATGCCGACGA
CGCGCGACTGGCAGAGGCTGGACGCCGACGAACGCGCGGCGGCGGTGCGCGTGATGCAGGCCTATGGCGGCATGGCGACC
GCGATGGACCGCGAGATCGGGCGACTCGTCGCGCACCTCAAGACCACGGGCGATTACGACAACACGATCTTCGTCTTCCT
GTCCGACAATGGCGCCGAGCCGACGAATCCCTTTGCCAGTCTGCGCAACCGGCTGTTCCTGCGGATGCAATATGATCTTT
CGACCGATAACATCGGGCGGCGGGGCAGTTTTTCGGCGATCGGGCCGGGCTGGGCAAGCGCCGCGGCGTCGCCCTTGTCA
GGTTACAAGTTCAGCGCCGCCGAGGGCGGGCTGCGCGTCCCGCTGATCATCGCCTGGCCGGGGCATGGCGCGATCCCGGC
GGGCGCGATCAACGACGGGCTGGCGCATGTCACCGACCTCTTGCCGACGCTTGCCGAACTGGCGGACGTGCCGCTGCACG
AAGGGACATGGCAGGGGCGGAGCGTCGAGCCGATCACGGGGCGCAGCCTCGTCCCGATGCTGAAGGGTGCTGCGGGCAGC
GTCCATGGCGACGCGCCGCTCGGTTACGAGCTGTCGGGCAATGCCGCGCTGTTTCGCGGCGATTACAAGCTGGTGCGCAA
CCTGCCGCCGACCGGCGACGGCCGGTGGCGGCTCTATGACATCAAGACGGACCCCGGCGAGACCCGCGACCTGTCGGCGG
CGATGCCCGATCGGTTCGCCGCGATGCTGTCCGACTACCGCGCCTATGCCAGGGCGAACGGCGTGCTCGACATGCCGGCG
GGTTATACCGCCGACGAACAGATCAACCGTTATGCGTGGGAGCAGCAGGGGCGCAAACGCGCGATCAAGGCCGGGCTGTG
GCTGGGCGGCGGGTTGATGGCGCTGGCGTTGCTGGTCTGGAGCTGGCGGCGGCGGCGCGCGCGGGGGTAA

Upstream 100 bases:

>100_bases
GCGCGCCCGAATATCGCGAGCGATAGGATCGCCGCGCACGCCCCATTGACTTGCCATTATATTGGCATAGTAAATGCCAT
ATCCCTTGGGGGTGGGAGTG

Downstream 100 bases:

>100_bases
TGTGGGCGCGGATGTGGGGTGCCTTGGGCGGTAGGCTGGATGGTTGAGGTTGTTGTCGGCTTTGGGGTGGAGAGCTGCCA
TAAACCCCTCTCCCCTTCAG

Product: sulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 609; Mature: 608

Protein sequence:

>609_residues
MAAGWRTTRRGRTGASRRAAIIALACLLGSTSGLAQSRAAPPRQPNIVILLADDWGFSDVGAFGSEIATPHIDALARAGM
RFANFHVSGSCSPTRAMLQTGVMNHRNGLGNMPETIPDEHRGKPGYDTVMNLRVVTIAELMKAAGYRTYLTGKWHLGSDA
KRLPEARGYDRAFSLADAGADNFEQRPIEGLYDKANWTENGRPATLPRDYYSSTFVVEKMIEYIEADRDSGKPFLASINF
LANHIPVQAPDSDIARYAAMYQDGWTALREARARRAAALGIVPAGTPMVTMPTTRDWQRLDADERAAAVRVMQAYGGMAT
AMDREIGRLVAHLKTTGDYDNTIFVFLSDNGAEPTNPFASLRNRLFLRMQYDLSTDNIGRRGSFSAIGPGWASAAASPLS
GYKFSAAEGGLRVPLIIAWPGHGAIPAGAINDGLAHVTDLLPTLAELADVPLHEGTWQGRSVEPITGRSLVPMLKGAAGS
VHGDAPLGYELSGNAALFRGDYKLVRNLPPTGDGRWRLYDIKTDPGETRDLSAAMPDRFAAMLSDYRAYARANGVLDMPA
GYTADEQINRYAWEQQGRKRAIKAGLWLGGGLMALALLVWSWRRRRARG

Sequences:

>Translated_609_residues
MAAGWRTTRRGRTGASRRAAIIALACLLGSTSGLAQSRAAPPRQPNIVILLADDWGFSDVGAFGSEIATPHIDALARAGM
RFANFHVSGSCSPTRAMLQTGVMNHRNGLGNMPETIPDEHRGKPGYDTVMNLRVVTIAELMKAAGYRTYLTGKWHLGSDA
KRLPEARGYDRAFSLADAGADNFEQRPIEGLYDKANWTENGRPATLPRDYYSSTFVVEKMIEYIEADRDSGKPFLASINF
LANHIPVQAPDSDIARYAAMYQDGWTALREARARRAAALGIVPAGTPMVTMPTTRDWQRLDADERAAAVRVMQAYGGMAT
AMDREIGRLVAHLKTTGDYDNTIFVFLSDNGAEPTNPFASLRNRLFLRMQYDLSTDNIGRRGSFSAIGPGWASAAASPLS
GYKFSAAEGGLRVPLIIAWPGHGAIPAGAINDGLAHVTDLLPTLAELADVPLHEGTWQGRSVEPITGRSLVPMLKGAAGS
VHGDAPLGYELSGNAALFRGDYKLVRNLPPTGDGRWRLYDIKTDPGETRDLSAAMPDRFAAMLSDYRAYARANGVLDMPA
GYTADEQINRYAWEQQGRKRAIKAGLWLGGGLMALALLVWSWRRRRARG
>Mature_608_residues
AAGWRTTRRGRTGASRRAAIIALACLLGSTSGLAQSRAAPPRQPNIVILLADDWGFSDVGAFGSEIATPHIDALARAGMR
FANFHVSGSCSPTRAMLQTGVMNHRNGLGNMPETIPDEHRGKPGYDTVMNLRVVTIAELMKAAGYRTYLTGKWHLGSDAK
RLPEARGYDRAFSLADAGADNFEQRPIEGLYDKANWTENGRPATLPRDYYSSTFVVEKMIEYIEADRDSGKPFLASINFL
ANHIPVQAPDSDIARYAAMYQDGWTALREARARRAAALGIVPAGTPMVTMPTTRDWQRLDADERAAAVRVMQAYGGMATA
MDREIGRLVAHLKTTGDYDNTIFVFLSDNGAEPTNPFASLRNRLFLRMQYDLSTDNIGRRGSFSAIGPGWASAAASPLSG
YKFSAAEGGLRVPLIIAWPGHGAIPAGAINDGLAHVTDLLPTLAELADVPLHEGTWQGRSVEPITGRSLVPMLKGAAGSV
HGDAPLGYELSGNAALFRGDYKLVRNLPPTGDGRWRLYDIKTDPGETRDLSAAMPDRFAAMLSDYRAYARANGVLDMPAG
YTADEQINRYAWEQQGRKRAIKAGLWLGGGLMALALLVWSWRRRRARG

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569405, Length=573, Percent_Identity=26.7015706806283, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI38569407, Length=421, Percent_Identity=28.5035629453682, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI109389362, Length=422, Percent_Identity=27.4881516587678, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI59797060, Length=575, Percent_Identity=24.3478260869565, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI146229331, Length=439, Percent_Identity=29.1571753986333, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI146229329, Length=439, Percent_Identity=29.1571753986333, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI6005990, Length=439, Percent_Identity=29.1571753986333, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI146229324, Length=439, Percent_Identity=29.1571753986333, Blast_Score=114, Evalue=4e-25,
Organism=Homo sapiens, GI45430057, Length=480, Percent_Identity=28.5416666666667, Blast_Score=113, Evalue=6e-25,
Organism=Homo sapiens, GI4506919, Length=569, Percent_Identity=25.1318101933216, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI31742482, Length=488, Percent_Identity=25.6147540983607, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI157266309, Length=628, Percent_Identity=24.203821656051, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI53831991, Length=470, Percent_Identity=25.3191489361702, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI4503899, Length=244, Percent_Identity=29.0983606557377, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI58743319, Length=577, Percent_Identity=22.7036395147314, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI71852586, Length=176, Percent_Identity=30.6818181818182, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1790233, Length=142, Percent_Identity=34.5070422535211, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790112, Length=516, Percent_Identity=21.8992248062016, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115533416, Length=541, Percent_Identity=24.9537892791128, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI115533418, Length=533, Percent_Identity=24.953095684803, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559078, Length=138, Percent_Identity=36.9565217391304, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24666109, Length=454, Percent_Identity=27.0925110132159, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24666175, Length=449, Percent_Identity=27.6169265033408, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI281366397, Length=436, Percent_Identity=26.605504587156, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281366395, Length=436, Percent_Identity=26.605504587156, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24666163, Length=436, Percent_Identity=26.605504587156, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281363223, Length=523, Percent_Identity=23.9005736137667, Blast_Score=105, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 66212; Mature: 66081

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAGWRTTRRGRTGASRRAAIIALACLLGSTSGLAQSRAAPPRQPNIVILLADDWGFSDV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEEEEECCCCCHHH
GAFGSEIATPHIDALARAGMRFANFHVSGSCSPTRAMLQTGVMNHRNGLGNMPETIPDEH
HHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RGKPGYDTVMNLRVVTIAELMKAAGYRTYLTGKWHLGSDAKRLPEARGYDRAFSLADAGA
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHCCCCCCCCHHHHHHHCCC
DNFEQRPIEGLYDKANWTENGRPATLPRDYYSSTFVVEKMIEYIEADRDSGKPFLASINF
CCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LANHIPVQAPDSDIARYAAMYQDGWTALREARARRAAALGIVPAGTPMVTMPTTRDWQRL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCCHHHC
DADERAAAVRVMQAYGGMATAMDREIGRLVAHLKTTGDYDNTIFVFLSDNGAEPTNPFAS
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHH
LRNRLFLRMQYDLSTDNIGRRGSFSAIGPGWASAAASPLSGYKFSAAEGGLRVPLIIAWP
HHHHEEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCCEEEEEEEEC
GHGAIPAGAINDGLAHVTDLLPTLAELADVPLHEGTWQGRSVEPITGRSLVPMLKGAAGS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCC
VHGDAPLGYELSGNAALFRGDYKLVRNLPPTGDGRWRLYDIKTDPGETRDLSAAMPDRFA
CCCCCCCCEEECCCEEEEECCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHCHHHHH
AMLSDYRAYARANGVLDMPAGYTADEQINRYAWEQQGRKRAIKAGLWLGGGLMALALLVW
HHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHH
SWRRRRARG
HHHHHHCCC
>Mature Secondary Structure 
AAGWRTTRRGRTGASRRAAIIALACLLGSTSGLAQSRAAPPRQPNIVILLADDWGFSDV
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCEEEEEECCCCCHHH
GAFGSEIATPHIDALARAGMRFANFHVSGSCSPTRAMLQTGVMNHRNGLGNMPETIPDEH
HHHHHHHCCCHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
RGKPGYDTVMNLRVVTIAELMKAAGYRTYLTGKWHLGSDAKRLPEARGYDRAFSLADAGA
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHCCCCCCCCHHHHHHHCCC
DNFEQRPIEGLYDKANWTENGRPATLPRDYYSSTFVVEKMIEYIEADRDSGKPFLASINF
CCCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LANHIPVQAPDSDIARYAAMYQDGWTALREARARRAAALGIVPAGTPMVTMPTTRDWQRL
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCCHHHC
DADERAAAVRVMQAYGGMATAMDREIGRLVAHLKTTGDYDNTIFVFLSDNGAEPTNPFAS
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHH
LRNRLFLRMQYDLSTDNIGRRGSFSAIGPGWASAAASPLSGYKFSAAEGGLRVPLIIAWP
HHHHEEEEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEECCCCCCEEEEEEEEC
GHGAIPAGAINDGLAHVTDLLPTLAELADVPLHEGTWQGRSVEPITGRSLVPMLKGAAGS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCC
VHGDAPLGYELSGNAALFRGDYKLVRNLPPTGDGRWRLYDIKTDPGETRDLSAAMPDRFA
CCCCCCCCEEECCCEEEEECCHHHHHCCCCCCCCCEEEEEEECCCCCCCCCHHHCHHHHH
AMLSDYRAYARANGVLDMPAGYTADEQINRYAWEQQGRKRAIKAGLWLGGGLMALALLVW
HHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHH
SWRRRRARG
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]