Click here to switch to the map view.

The map label for this gene is lig [H]

Identifier: 103485784

GI number: 103485784

Start: 286755

End: 287768

Strand: Direct

Name: lig [H]

Synonym: Sala_0289

Alternate gene names: 103485784

Gene position: 286755-287768 (Clockwise)

Preceding gene: 103485783

Following gene: 103485785

Centisome position: 8.57

GC content: 67.95

Gene sequence:

>1014_bases
ATGGCAAGGGCGACGACGTGGATCGAGCCGCATCCGGGCGGCATCTATGTGAAGCCCGCCGACCTGTGGATTGACCCGTC
GCGCCCTGTCCCCCGCGCCGCGGTGACGCACGGTCATGCCGATCATGCGCGCAGCGGCCACGGTGCGGTGTTCGCGACCC
CCGAGACGTTGGCGATCATGGCGCTGCGCTATGGCGTCGACGTTGCGGCGAGCCATAACCGGGGGTTCGCCTATGGCGAG
GGGTTCGAGCGCGGCGGCGTGCGTTTTTCCTTCCATCCCGCGGGGCATGTGCTCGGCAGCGCACAGATATTGATGGAATA
TCGGGGCGAACGGATCGTCGTCACCGGCGATTACAAGCGCCGCGCCGACCCCACCTGCGCGGCGTTCGAGGTGGTGCCGT
GCGACATCTTCATCACCGAGGCGACCTTCGGCCTGCCGGTGTTCCGCCATCCGCCGACACAGGGCGAGATCGCCAAGCTG
ATCGACGCGGTGCGCGCCGAACCCGACCGCTGCGTCCTCGTCGGCGCCTATGCGCTCGGCAAGGCACAGCGCCTGATCGC
CGAACTGCGCGGCGCGGGATGGGATGCGCCCATCTATATCCACGGCGCGCTCGAGAAGATGTGCACGCTTTATGCGGTGC
ACGGCGTCGATCTCGGCGAACTTCGGCTCGTCTCGGAAACCGACAGGGCCGACATGGCGGGGCAGATCGTCGTCGCGCCG
CCCGCCGCCCTCAACGACCGCTGGTCGCGGCGCTTGCCCGATCCGTTGACCGCGATGGCGTCGGGCTGGATGCGCGTGCG
CCAGCGCGCGCGGCAGCGGATGGTCGAACTGCCGCTCGTCATCTCGGACCACGCCGACTGGGACGAACTGACGACGACGA
TTGCTGAGGTGAACCCCAAGGAGACATGGATCACCCACGGCAGCGAGGACGGTTTGCTGCGCTGGTGCGAATTGCATCAG
CGTCAGGCGCGCGCGCTGCACCTCGTCGGTCGCGATCTGGAGGAAGAGGCGTGA

Upstream 100 bases:

>100_bases
CAACCTTGGCGGAACGATCGCGCGGCGCTGGGAGCCGGGTGGCCTGATCGTCGACATCACGCTCCCCGCACGGTGGCGCG
AGGCCTGAGCGCGGCGGCCG

Downstream 100 bases:

>100_bases
AGGCGCTTGCCGCCCTGATCGACCGGCTGATCTACACGCGCTCGCGCAACAGCAAGCTGGCGCTGATTGCCGATTATCTG
AGGTGCACGCCCGACCCCGA

Product: putative mRNA 3-end processing factor

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MARATTWIEPHPGGIYVKPADLWIDPSRPVPRAAVTHGHADHARSGHGAVFATPETLAIMALRYGVDVAASHNRGFAYGE
GFERGGVRFSFHPAGHVLGSAQILMEYRGERIVVTGDYKRRADPTCAAFEVVPCDIFITEATFGLPVFRHPPTQGEIAKL
IDAVRAEPDRCVLVGAYALGKAQRLIAELRGAGWDAPIYIHGALEKMCTLYAVHGVDLGELRLVSETDRADMAGQIVVAP
PAALNDRWSRRLPDPLTAMASGWMRVRQRARQRMVELPLVISDHADWDELTTTIAEVNPKETWITHGSEDGLLRWCELHQ
RQARALHLVGRDLEEEA

Sequences:

>Translated_337_residues
MARATTWIEPHPGGIYVKPADLWIDPSRPVPRAAVTHGHADHARSGHGAVFATPETLAIMALRYGVDVAASHNRGFAYGE
GFERGGVRFSFHPAGHVLGSAQILMEYRGERIVVTGDYKRRADPTCAAFEVVPCDIFITEATFGLPVFRHPPTQGEIAKL
IDAVRAEPDRCVLVGAYALGKAQRLIAELRGAGWDAPIYIHGALEKMCTLYAVHGVDLGELRLVSETDRADMAGQIVVAP
PAALNDRWSRRLPDPLTAMASGWMRVRQRARQRMVELPLVISDHADWDELTTTIAEVNPKETWITHGSEDGLLRWCELHQ
RQARALHLVGRDLEEEA
>Mature_336_residues
ARATTWIEPHPGGIYVKPADLWIDPSRPVPRAAVTHGHADHARSGHGAVFATPETLAIMALRYGVDVAASHNRGFAYGEG
FERGGVRFSFHPAGHVLGSAQILMEYRGERIVVTGDYKRRADPTCAAFEVVPCDIFITEATFGLPVFRHPPTQGEIAKLI
DAVRAEPDRCVLVGAYALGKAQRLIAELRGAGWDAPIYIHGALEKMCTLYAVHGVDLGELRLVSETDRADMAGQIVVAPP
AALNDRWSRRLPDPLTAMASGWMRVRQRARQRMVELPLVISDHADWDELTTTIAEVNPKETWITHGSEDGLLRWCELHQR
QARALHLVGRDLEEEA

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323307, Length=144, Percent_Identity=31.9444444444444, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24648013, Length=292, Percent_Identity=25.6849315068493, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 37192; Mature: 37061

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARATTWIEPHPGGIYVKPADLWIDPSRPVPRAAVTHGHADHARSGHGAVFATPETLAIM
CCCCCCEECCCCCEEEEEEHHEEECCCCCCCCHHHCCCCHHHCCCCCCEEEECCHHHHHH
ALRYGVDVAASHNRGFAYGEGFERGGVRFSFHPAGHVLGSAQILMEYRGERIVVTGDYKR
HHHHCCEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCC
RADPTCAAFEVVPCDIFITEATFGLPVFRHPPTQGEIAKLIDAVRAEPDRCVLVGAYALG
CCCCCEEEEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHCCCCCEEEEEHHHHH
KAQRLIAELRGAGWDAPIYIHGALEKMCTLYAVHGVDLGELRLVSETDRADMAGQIVVAP
HHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEC
PAALNDRWSRRLPDPLTAMASGWMRVRQRARQRMVELPLVISDHADWDELTTTIAEVNPK
CCHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCC
ETWITHGSEDGLLRWCELHQRQARALHLVGRDLEEEA
HHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
ARATTWIEPHPGGIYVKPADLWIDPSRPVPRAAVTHGHADHARSGHGAVFATPETLAIM
CCCCCEECCCCCEEEEEEHHEEECCCCCCCCHHHCCCCHHHCCCCCCEEEECCHHHHHH
ALRYGVDVAASHNRGFAYGEGFERGGVRFSFHPAGHVLGSAQILMEYRGERIVVTGDYKR
HHHHCCEEEECCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCC
RADPTCAAFEVVPCDIFITEATFGLPVFRHPPTQGEIAKLIDAVRAEPDRCVLVGAYALG
CCCCCEEEEEEEEEEEEEECCCCCCCEEECCCCCCHHHHHHHHHHCCCCCEEEEEHHHHH
KAQRLIAELRGAGWDAPIYIHGALEKMCTLYAVHGVDLGELRLVSETDRADMAGQIVVAP
HHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCEEEEEC
PAALNDRWSRRLPDPLTAMASGWMRVRQRARQRMVELPLVISDHADWDELTTTIAEVNPK
CCHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCC
ETWITHGSEDGLLRWCELHQRQARALHLVGRDLEEEA
HHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA