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The map label for this gene is yafC [H]

Identifier: 158340507

GI number: 158340507

Start: 55983

End: 56918

Strand: Reverse

Name: yafC [H]

Synonym: AM1_C0052

Alternate gene names: 158340507

Gene position: 56918-55983 (Counterclockwise)

Preceding gene: 158340510

Following gene: 158340504

Centisome position: 20.84

GC content: 46.69

Gene sequence:

>936_bases
ATGAAGAGCCTGTCCAACATAAAGACTTTTGTCCGTGTTGCTGAAGTGGAGAGCTTTGCCAGAGCCTCAAATATTTTGGG
TCTATCGACGTCAGCCGTGAGCAAGGCCGTGGCTCGGCTCGAAGCTGATTTGGGTGTAAAGCTATTTCATCGCACCACTC
GTAGTGTTAGCCTTACCCCCGATGGCAAACAATTTTATGAAGGCTGTCAGCAACTATTGCTCGAATTTGATGCCCTCACT
GCTGAGGTTCAAGGCAGTCGAGCAACGCCTAGGGGACAATTGACGATTAGTGCTCCAGCAGCGTTTGGGCGTCTGTGTTT
AGTCCCTCTATTACAGTCTTTCATGCAGTCCTATCCCGAAATTACTTTAAATATTTCCATAGATGATCACGCTATAGATC
TCGCTGCCCAGGGTATTGATATTGTGATTCGCACCGGACAACTGGCTGATAGTGCTAATTTGATTGCGAGTCGATTAGTT
ACTTATCGACTGGTGGTATGTGCTTCGCCACACTACCTCGCAGAGCACGGAGAGCCCCAACATCCAGAACAGTTACAAAG
ACACTCTTGTCTTAATTTTCGTAATCCCGATACAGGCCGATTCTTTCCTTGGGTGCTTGAGATTGATGGAGCAGTAGAGT
CTTATACGGTGAGTGGCCCCCTTGTGTTTGATAATGCGGATGCGGTCGTGAGAAGTTCAATCTCTAGCCTAGGGCTGAGC
CAGATGCCCTCCTTTTTAGCAAAGGAAGCTGTATCGAGAGGACAACTGGTGGAAGTGTTAAATTCCTATCAGCCCCCAGA
GACTCCTGTTTGGATTTGTTATCTCGATCGCAATTTTGTCTCTCCTAGAATTCGAGCCTTCGTGGAATTTATGAAAAGCG
AGAAAAGCCATTTGTCTACAATGTGCTCTTTAGCAGAACGCATAGCTGTATCATAA

Upstream 100 bases:

>100_bases
AACGGCGCGTTGCTGGCTTGATTACAAGATATTTGGATTACAATCCTTTGAGAAGGGGTTTAATATCACTTCTTTATCCA
CTTTTTCTCACTAATAAACT

Downstream 100 bases:

>100_bases
GTGTGGCTTCAAGCAACTGTTGGGCAAGGCTTTCAGCCCTATAGCGTCAATTGCACGGATCATTGTCGGCCCCCTATCTG
ACTACTTGACTCTGAGGTAT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MKSLSNIKTFVRVAEVESFARASNILGLSTSAVSKAVARLEADLGVKLFHRTTRSVSLTPDGKQFYEGCQQLLLEFDALT
AEVQGSRATPRGQLTISAPAAFGRLCLVPLLQSFMQSYPEITLNISIDDHAIDLAAQGIDIVIRTGQLADSANLIASRLV
TYRLVVCASPHYLAEHGEPQHPEQLQRHSCLNFRNPDTGRFFPWVLEIDGAVESYTVSGPLVFDNADAVVRSSISSLGLS
QMPSFLAKEAVSRGQLVEVLNSYQPPETPVWICYLDRNFVSPRIRAFVEFMKSEKSHLSTMCSLAERIAVS

Sequences:

>Translated_311_residues
MKSLSNIKTFVRVAEVESFARASNILGLSTSAVSKAVARLEADLGVKLFHRTTRSVSLTPDGKQFYEGCQQLLLEFDALT
AEVQGSRATPRGQLTISAPAAFGRLCLVPLLQSFMQSYPEITLNISIDDHAIDLAAQGIDIVIRTGQLADSANLIASRLV
TYRLVVCASPHYLAEHGEPQHPEQLQRHSCLNFRNPDTGRFFPWVLEIDGAVESYTVSGPLVFDNADAVVRSSISSLGLS
QMPSFLAKEAVSRGQLVEVLNSYQPPETPVWICYLDRNFVSPRIRAFVEFMKSEKSHLSTMCSLAERIAVS
>Mature_311_residues
MKSLSNIKTFVRVAEVESFARASNILGLSTSAVSKAVARLEADLGVKLFHRTTRSVSLTPDGKQFYEGCQQLLLEFDALT
AEVQGSRATPRGQLTISAPAAFGRLCLVPLLQSFMQSYPEITLNISIDDHAIDLAAQGIDIVIRTGQLADSANLIASRLV
TYRLVVCASPHYLAEHGEPQHPEQLQRHSCLNFRNPDTGRFFPWVLEIDGAVESYTVSGPLVFDNADAVVRSSISSLGLS
QMPSFLAKEAVSRGQLVEVLNSYQPPETPVWICYLDRNFVSPRIRAFVEFMKSEKSHLSTMCSLAERIAVS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=34.8122866894198, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=32.6460481099656, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=32.0819112627986, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI87081978, Length=290, Percent_Identity=34.1379310344828, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=30.2083333333333, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1789440, Length=288, Percent_Identity=28.125, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787589, Length=292, Percent_Identity=27.0547945205479, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1788706, Length=260, Percent_Identity=30.3846153846154, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=26.0416666666667, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790011, Length=303, Percent_Identity=24.7524752475248, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693105, Length=124, Percent_Identity=34.6774193548387, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786713, Length=272, Percent_Identity=26.1029411764706, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=123, Percent_Identity=30.0813008130081, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI157672245, Length=120, Percent_Identity=34.1666666666667, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786448, Length=258, Percent_Identity=25.1937984496124, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786508, Length=271, Percent_Identity=26.9372693726937, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789204, Length=123, Percent_Identity=30.8943089430894, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082132, Length=293, Percent_Identity=24.2320819112628, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788297, Length=140, Percent_Identity=29.2857142857143, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788748, Length=63, Percent_Identity=52.3809523809524, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34190; Mature: 34190

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLSNIKTFVRVAEVESFARASNILGLSTSAVSKAVARLEADLGVKLFHRTTRSVSLTP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCEEEECC
DGKQFYEGCQQLLLEFDALTAEVQGSRATPRGQLTISAPAAFGRLCLVPLLQSFMQSYPE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
ITLNISIDDHAIDLAAQGIDIVIRTGQLADSANLIASRLVTYRLVVCASPHYLAEHGEPQ
EEEEEEECCHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
HPEQLQRHSCLNFRNPDTGRFFPWVLEIDGAVESYTVSGPLVFDNADAVVRSSISSLGLS
CHHHHHHHHCCCCCCCCCCCEEEEEEEECCCHHEEEECCCEEECCCHHHHHHHHHHCCHH
QMPSFLAKEAVSRGQLVEVLNSYQPPETPVWICYLDRNFVSPRIRAFVEFMKSEKSHLST
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
MCSLAERIAVS
HHHHHHHHCCC
>Mature Secondary Structure
MKSLSNIKTFVRVAEVESFARASNILGLSTSAVSKAVARLEADLGVKLFHRTTRSVSLTP
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCEEEECC
DGKQFYEGCQQLLLEFDALTAEVQGSRATPRGQLTISAPAAFGRLCLVPLLQSFMQSYPE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCC
ITLNISIDDHAIDLAAQGIDIVIRTGQLADSANLIASRLVTYRLVVCASPHYLAEHGEPQ
EEEEEEECCHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
HPEQLQRHSCLNFRNPDTGRFFPWVLEIDGAVESYTVSGPLVFDNADAVVRSSISSLGLS
CHHHHHHHHCCCCCCCCCCCEEEEEEEECCCHHEEEECCCEEECCCHHHHHHHHHHCCHH
QMPSFLAKEAVSRGQLVEVLNSYQPPETPVWICYLDRNFVSPRIRAFVEFMKSEKSHLST
HHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
MCSLAERIAVS
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]