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The map label for this gene is traI [H]

Identifier: 145301506

GI number: 145301506

Start: 121325

End: 126442

Strand: Direct

Name: traI [H]

Synonym: ASA_P5G128

Alternate gene names: 145301506

Gene position: 121325-126442 (Clockwise)

Preceding gene: 145301505

Following gene: 145301508

Centisome position: 78.22

GC content: 58.5

Gene sequence:

>5118_bases
ATGCTGTCACTGGGCAGCTCGGCCTACTACGCTGCCGAGGAAAACTACTACGCCATGGGCGATCTCGAGTCGGTCTGGAT
GGGGGAAGGGGCTGACCGCCTTGGACTGAGTGGCCCCATTGACGGGGCCACCCTCGATGCCATCGCCCAGGGCAAACTCC
CCGATGGCACGGAACTCTCGCGCATCGTGGATGGCAAGCAGACCCACCGCACCGGCTATGACCTGACGTTTTCGGCCCCC
AAGAGTGTCTCCGTGATGGCACTGGTGGCGGGTGACGAGCGCTTTCTGGCCGCCCACCATCACGCTGTGGCGGTGGCAAT
GAAGGAGGTCGAGGCGCTGGCCAGCACCCGCATCATGACCGATGGCATCACCCGCACCGAGACCACCGGCAATATCGTGG
CGGCCCTCTACACCCACGACACCTCCCGCGAACTTGATCCGCAGCTGCACACCCACTCACTGGTGCTCAATGCCACCTAT
GCAGAAGGCAAATGGCGGGCGCTGAGCAGTGATGCCGCCCACATGAACAGCGGCTTTGGCAAAGACATCTTTAACAACAA
ACTGGCGCTCGGGCAGATATACCGCCACGCCCTGCGCCAGGACGTCGAGGCGATGGGTTTTGAAACAGAGGTCACCGGCA
AGCATGGCCTGTGGGAGCTCAAGGGGGTGCCGACCGAACCATTCAGCCAACGCAGCCAGCAGATAAACGACGCGGTCGGC
CCCGATGCCTCACCCCAGTCCCGCGATGCCGCCGCGCTCGATACCCGCAAGGACAAGGCGGTTGCCGACCCCGATCTACT
GATCGCCGATTGGCGTGATCGCCTGGGCAAAGCAGGCTTTGAACTGCCCCTCTATCTCGCCAAGGCCGACGAACGCGCCC
AGGGATACACCGTCCCCACGCCAGCTGGCACGGATATCACCCAAGCCGTGAGCCAGGCGATATCCATACTTTCGGATAAA
AAGGTACAGTTCTCCTACTCCGAATTACTGGCCGCCACGGTGAGCCAGCTCCCCGTCGAACAGGGGTTGATCACCCAGGC
CCGCGAGGGTATCGAGCAGGCGATTGGACGCGAGCGCCTCATCCCGCTCGACAAGGAAAAAGGGATCTTCACCTCCGATA
TCCATCTGCTCAACGAATTGTCCATCGCCCAGCTGGCCAACGAGTTCAACAAGCGCCCCCCGATAGCCACCTTTGCCGAG
CGGGCAACCCCGCGTGATCGTCCCTATGCCAACGCCTACTCCGTGTTGGCCCAGGACAAGGCCCCGCTGGCTATCCTGTC
CGGACGGGGTGGCATGGCCCAAACCATCGAGCGCATGGAAGATGCCGTGCTCATGGCCAGCGAACAGGGGCGTGAGGTCA
CCATCCTGGCCAGCGACAATCGCTCGGCTCGCCTGCTGGCACAAAGCCAGCCTCTGGCAGGCAATATTGCCCCGCGTCAC
ACCCTCAATGCCGCCACGGTCTTTGCCCCTCATAGCACCCTCATTGTCGAGCAGGCTGAATCCCTGACCCTCAAAGAAAC
GCTGCTCATCCTGGAAAAGGCACGGGCCAGCGATGTCCAGGTACTGATGCTCGACAGTGAGCGCCAGCGCGGCGTCGGCA
ATGCGCTCTCCGTCCTCAAGCAAGCCAGCGTGCCGCAGTACCGTTTCTATGATGCGCCCAACATCGAGGCCACCGTCCAG
AGCGTGCCTGACAAGCCAGCGCGTTTTGACGCCCTGGCACAGGACTACGCGCATCGTCTGCAGCAAGGCGAGCAGGTGGT
TGCCCAGGTCTCCGGGACACGGGATCAGCAGCAGCTAACCAGCCATATCCGCAGCGCCTTGCGGGATATCGGCCAACTGC
ACGGGCAGGATCACACCCTCAACGTCCTTGCCCCGGTATGGCTCGATAGCAAGACCCGCCATCAGCGTGACACCTATCGC
GAGGGGATGGTCATGGAGCGGTGGGACGACAAGGGTAAAACCATGGATCGCTATCGCATTGATCTCGTCGCAGACAAGAC
CCACTCGCTGGTGCTGGCCAACGAGCAGGGGGAGAAACACACCATCAAGATCCGCGCCCTGGACAGCAACTGGTCGCTGT
TTGAAAGCAAGCGCATCGAGGTCGCGGCGGGCGACACACTCCGGGTGCTCGGGCGAGAGGCCGAGGGCACCCTCAAGGCG
CAACAGACCCTGCAGGTACTGGACGCGGCCCCTGGCCACCTGCACCTCAAGACCCCGACCGGTGAGCTGCAACTGCCAAC
AGACAGGGCACTCAAGCTCGACCACAACTATGTTACCGGCGTGGGCGTCACCGCCAGCCAGGAGGCCACCGTACTGGCCG
CCATGAGTGCCCGCCAGATGAGTGGCACAGGGCTTAACCAACTGGCCAGAAGTGGCCAGCATATTCACATCTACACCCCG
CTTGATCAGATGCGGGCACAGAGCAAGTTAGCCAGTCATCCCCAGTTCCAGCTGGCCAGTGAAAAGCTCAAAGCCCACGG
CGACAGCGACCAGCTCGATACTACGCTCAAGCAGGCCACCGCCAGCCTGCACACAGCGGCTGAGCAAGCCCTGCATTTGG
GGCTGGCCCAGGTGGAAGCCAAAGGCATCGTCTTTTCCACCTCAAGCTTGCTGGCCGCCGCCCTGGATTTTGCCCCGGCA
ACCCCGATTGACTCAATCAGCGCCGTGCTCGATGACAAACTCGCCAAGGGTGACCTGCTGCCGGTGCCCGGCAAGCGCGG
CGACGTGGTCTCTCGAGCCAGCTTTGACATGGAAAAGTTCATTATCGCCACCATTGCCCAAGGCAAGGGAACCGCGACCC
CCTACCTGCAGCAGGTACCCGACCCCCAACTGGCAGGGCTAACCCCTGGCCAGGCACAATCCACTCGCCTGATCCTGGAG
AGCAACGACCAGTTCATCGCCATCCAGGGCTATGCCGGTGTGGGTAAAACCACCCAGTTCAAGGCTGTGCTGAGTGCACT
CGACACCCTGCCCCCGGAACAGCGCCCGACCGTGGTCGGGATTGGCCCCACCCACCGGGCCGTCCATGAAATGCAGTCCA
CCGGGGTCAAGGCACAGACGCTGGCCTCGTTTCTCTCGGAGAGTCGCCTGCAGGCCATGGCAGGGGAGCAGCAGGACCAC
AGCCGCACCCTGTTCCTGGTGGATGAAAGCTCGATGATTGGCAACCGCGACATGGCGGAGTTTTACCAGCGGGTGGCCGC
CAGTGGCGCAAGGGTGGTCAGCAGCGGTGATACCGCGCAGCTCAAAGCCATCTCGTCAGGTGCCCCGTTCCAACTGATGC
AAGAGCGCAGCGCGGTCGATGTGGCTGTCATGAAAGAGATTGTCCGCCAGCGCCCGGAGCTCAAACCGGCGATCTACAGC
TTGATAGATGGCAACCTCACCCAGTCACTGGCACAGCGCGAAGCGGTGCAACCGGCTGTGGTACCCCGAGACCCGGCAAA
CAAACCGGATGCCTGGACACCGGATCGCTCGGTGATTGAGGCAAAGAACCCCGCCGAACTGGTGGTCAAAGATTATGTCA
GCCGCACCCGTCTTACACGGGATAACACCATGGTGATCGTGCATCTCAATGAGGTGCGCCACGGTATTAACGCCGCAATA
CACCAGGCACTGTTTGATAAAGGGGAATTAGGTCCACGCCAGACCAGCCTGACCATTCTTGATCCGGTGCGCATTGAAGA
AAATAGCCTGCGTAGCAGTGAGCAGGTACAGAAAAATGCGCTCCTTGGTAAAGTGGCCGTGCTTAACCAGCACTATTACA
CCATCAGTGGTATCGACCCCCAGGCCGGGACAATGACCATCAAGGATAATGAGGGCAAGGTGCGACTCATCTCCAATATC
GAAAACACCGCCCATGATCTCGCTATCTATCAACCGAGGGAAATAAAGGTCAGTGAAGGCGATAAGATCCGCTTCACCCG
CACCGTCAATGAACACGGCCATGTAGCCAATAGCCAGTGGCAGGTAAAACGCATCGAGGATAATGGCGCGATAGTGCTGC
ACGATGGCAATAACGAGAAAACCGTTCGCCCCGACCAATTTAAAGAAGACCAGCACATTGATTTGGGATATGCCATTACC
GCCTATGGTGCGCAAGGGGCGAGCAGTACTTACGCCATCGAATTACAGGCGATCAAAGTCGTAAATAGAAACTTGATTAC
CCTGTCGTCTGCGTATGTCCCCGCCTCACGTGCCAAAGAACATATGCAGACCTATACCGATGATAAGGAAGGCTGGATTA
ACTTGCTCAATAAAAACCTCAAGAGCCAGGTTAGTACCGCCCACGATGCGCTCGAAGGAGACCAGATTAAAGGGCAAAAG
GTCGCAGATATGTTATTGGGTACCGCCTCGACGATGCGCTCTACCGCATTAGGACGGCATGTGCTGAAGACCCATCAACT
CGATGAGCAGCAGCATATGGGAAAATACATTGCACCAGGCAAAAAATACCCGACCCCGCACGCTGCCTTTCCGGTGTGGG
ATAATAATGGTAAACCGGCAGGGGCTGCCATGGTGGAGCTGCAAAGCCATCACCAAAATAAAGGCCCTACCCTGGACAGT
GAATATCGACTGGTGGCAAATGAACGAGCCGAGTTTATCGGACTCCAGCGTGCCAGTAATGGCGAAACCCGTATCGCCAC
CAGTTTGGTTGATGGAATTATCATGGCAGCCAAGCATCCACAAAGTGGAATATTGGTCAGCATTAACGGCGCACCACCAC
CATTTAATGTCAATCGGATGACCGGGGGTAAATTGGTTGTGTCGGACACGGATGCGCAGCACCTGCAAAAAGAGTCAGAG
CGTGAGTTACCACTGCCACAAGATATGACCACCAAAGAATCCAAACGCCAGGACGAGCTGATAAAAACAGTGGCCAGGGA
AAAAGAACACCCGGATATCAAACTGCCTGATGATAAACAGCATGCGGTCAATCGCGACGACAAGCGACTCCACAACGATA
TCAATCAACTCAATAAAGACGCGGAGTTAAGTGAGCGACAATTGCGTAAGTTGGCAGAAATCGGAGAAGTGGCCAAAGCC
AAATTTACCCATGAACTCCACGACAAACTGGATAAGCTGGAAAGGGAGATCATCAAGGAATTGACCAAGGGGGAGTAA

Upstream 100 bases:

>100_bases
AAAAATCCGAACGGACACAGCAAGAAGCGGCGCGGCGCGAAGAGGTCAACATTAACCATCACCACCAAGAGCCGGGTGGT
GACGAGCCGGAGTATTACTG

Downstream 100 bases:

>100_bases
AAAAGAAACCGGCCATGGGCCGGTTTCTTTTTTTGTCAGTCCTGCTCATCGTCAGTAGCAGGAAAGAAGGGCTCCATCTT
TTCTGCCACCTTCCTATCAA

Product: conjugal transfer nickase/helicase TraI

Products: NA

Alternate protein names: DNA helicase I [H]

Number of amino acids: Translated: 1705; Mature: 1705

Protein sequence:

>1705_residues
MLSLGSSAYYAAEENYYAMGDLESVWMGEGADRLGLSGPIDGATLDAIAQGKLPDGTELSRIVDGKQTHRTGYDLTFSAP
KSVSVMALVAGDERFLAAHHHAVAVAMKEVEALASTRIMTDGITRTETTGNIVAALYTHDTSRELDPQLHTHSLVLNATY
AEGKWRALSSDAAHMNSGFGKDIFNNKLALGQIYRHALRQDVEAMGFETEVTGKHGLWELKGVPTEPFSQRSQQINDAVG
PDASPQSRDAAALDTRKDKAVADPDLLIADWRDRLGKAGFELPLYLAKADERAQGYTVPTPAGTDITQAVSQAISILSDK
KVQFSYSELLAATVSQLPVEQGLITQAREGIEQAIGRERLIPLDKEKGIFTSDIHLLNELSIAQLANEFNKRPPIATFAE
RATPRDRPYANAYSVLAQDKAPLAILSGRGGMAQTIERMEDAVLMASEQGREVTILASDNRSARLLAQSQPLAGNIAPRH
TLNAATVFAPHSTLIVEQAESLTLKETLLILEKARASDVQVLMLDSERQRGVGNALSVLKQASVPQYRFYDAPNIEATVQ
SVPDKPARFDALAQDYAHRLQQGEQVVAQVSGTRDQQQLTSHIRSALRDIGQLHGQDHTLNVLAPVWLDSKTRHQRDTYR
EGMVMERWDDKGKTMDRYRIDLVADKTHSLVLANEQGEKHTIKIRALDSNWSLFESKRIEVAAGDTLRVLGREAEGTLKA
QQTLQVLDAAPGHLHLKTPTGELQLPTDRALKLDHNYVTGVGVTASQEATVLAAMSARQMSGTGLNQLARSGQHIHIYTP
LDQMRAQSKLASHPQFQLASEKLKAHGDSDQLDTTLKQATASLHTAAEQALHLGLAQVEAKGIVFSTSSLLAAALDFAPA
TPIDSISAVLDDKLAKGDLLPVPGKRGDVVSRASFDMEKFIIATIAQGKGTATPYLQQVPDPQLAGLTPGQAQSTRLILE
SNDQFIAIQGYAGVGKTTQFKAVLSALDTLPPEQRPTVVGIGPTHRAVHEMQSTGVKAQTLASFLSESRLQAMAGEQQDH
SRTLFLVDESSMIGNRDMAEFYQRVAASGARVVSSGDTAQLKAISSGAPFQLMQERSAVDVAVMKEIVRQRPELKPAIYS
LIDGNLTQSLAQREAVQPAVVPRDPANKPDAWTPDRSVIEAKNPAELVVKDYVSRTRLTRDNTMVIVHLNEVRHGINAAI
HQALFDKGELGPRQTSLTILDPVRIEENSLRSSEQVQKNALLGKVAVLNQHYYTISGIDPQAGTMTIKDNEGKVRLISNI
ENTAHDLAIYQPREIKVSEGDKIRFTRTVNEHGHVANSQWQVKRIEDNGAIVLHDGNNEKTVRPDQFKEDQHIDLGYAIT
AYGAQGASSTYAIELQAIKVVNRNLITLSSAYVPASRAKEHMQTYTDDKEGWINLLNKNLKSQVSTAHDALEGDQIKGQK
VADMLLGTASTMRSTALGRHVLKTHQLDEQQHMGKYIAPGKKYPTPHAAFPVWDNNGKPAGAAMVELQSHHQNKGPTLDS
EYRLVANERAEFIGLQRASNGETRIATSLVDGIIMAAKHPQSGILVSINGAPPPFNVNRMTGGKLVVSDTDAQHLQKESE
RELPLPQDMTTKESKRQDELIKTVAREKEHPDIKLPDDKQHAVNRDDKRLHNDINQLNKDAELSERQLRKLAEIGEVAKA
KFTHELHDKLDKLEREIIKELTKGE

Sequences:

>Translated_1705_residues
MLSLGSSAYYAAEENYYAMGDLESVWMGEGADRLGLSGPIDGATLDAIAQGKLPDGTELSRIVDGKQTHRTGYDLTFSAP
KSVSVMALVAGDERFLAAHHHAVAVAMKEVEALASTRIMTDGITRTETTGNIVAALYTHDTSRELDPQLHTHSLVLNATY
AEGKWRALSSDAAHMNSGFGKDIFNNKLALGQIYRHALRQDVEAMGFETEVTGKHGLWELKGVPTEPFSQRSQQINDAVG
PDASPQSRDAAALDTRKDKAVADPDLLIADWRDRLGKAGFELPLYLAKADERAQGYTVPTPAGTDITQAVSQAISILSDK
KVQFSYSELLAATVSQLPVEQGLITQAREGIEQAIGRERLIPLDKEKGIFTSDIHLLNELSIAQLANEFNKRPPIATFAE
RATPRDRPYANAYSVLAQDKAPLAILSGRGGMAQTIERMEDAVLMASEQGREVTILASDNRSARLLAQSQPLAGNIAPRH
TLNAATVFAPHSTLIVEQAESLTLKETLLILEKARASDVQVLMLDSERQRGVGNALSVLKQASVPQYRFYDAPNIEATVQ
SVPDKPARFDALAQDYAHRLQQGEQVVAQVSGTRDQQQLTSHIRSALRDIGQLHGQDHTLNVLAPVWLDSKTRHQRDTYR
EGMVMERWDDKGKTMDRYRIDLVADKTHSLVLANEQGEKHTIKIRALDSNWSLFESKRIEVAAGDTLRVLGREAEGTLKA
QQTLQVLDAAPGHLHLKTPTGELQLPTDRALKLDHNYVTGVGVTASQEATVLAAMSARQMSGTGLNQLARSGQHIHIYTP
LDQMRAQSKLASHPQFQLASEKLKAHGDSDQLDTTLKQATASLHTAAEQALHLGLAQVEAKGIVFSTSSLLAAALDFAPA
TPIDSISAVLDDKLAKGDLLPVPGKRGDVVSRASFDMEKFIIATIAQGKGTATPYLQQVPDPQLAGLTPGQAQSTRLILE
SNDQFIAIQGYAGVGKTTQFKAVLSALDTLPPEQRPTVVGIGPTHRAVHEMQSTGVKAQTLASFLSESRLQAMAGEQQDH
SRTLFLVDESSMIGNRDMAEFYQRVAASGARVVSSGDTAQLKAISSGAPFQLMQERSAVDVAVMKEIVRQRPELKPAIYS
LIDGNLTQSLAQREAVQPAVVPRDPANKPDAWTPDRSVIEAKNPAELVVKDYVSRTRLTRDNTMVIVHLNEVRHGINAAI
HQALFDKGELGPRQTSLTILDPVRIEENSLRSSEQVQKNALLGKVAVLNQHYYTISGIDPQAGTMTIKDNEGKVRLISNI
ENTAHDLAIYQPREIKVSEGDKIRFTRTVNEHGHVANSQWQVKRIEDNGAIVLHDGNNEKTVRPDQFKEDQHIDLGYAIT
AYGAQGASSTYAIELQAIKVVNRNLITLSSAYVPASRAKEHMQTYTDDKEGWINLLNKNLKSQVSTAHDALEGDQIKGQK
VADMLLGTASTMRSTALGRHVLKTHQLDEQQHMGKYIAPGKKYPTPHAAFPVWDNNGKPAGAAMVELQSHHQNKGPTLDS
EYRLVANERAEFIGLQRASNGETRIATSLVDGIIMAAKHPQSGILVSINGAPPPFNVNRMTGGKLVVSDTDAQHLQKESE
RELPLPQDMTTKESKRQDELIKTVAREKEHPDIKLPDDKQHAVNRDDKRLHNDINQLNKDAELSERQLRKLAEIGEVAKA
KFTHELHDKLDKLEREIIKELTKGE
>Mature_1705_residues
MLSLGSSAYYAAEENYYAMGDLESVWMGEGADRLGLSGPIDGATLDAIAQGKLPDGTELSRIVDGKQTHRTGYDLTFSAP
KSVSVMALVAGDERFLAAHHHAVAVAMKEVEALASTRIMTDGITRTETTGNIVAALYTHDTSRELDPQLHTHSLVLNATY
AEGKWRALSSDAAHMNSGFGKDIFNNKLALGQIYRHALRQDVEAMGFETEVTGKHGLWELKGVPTEPFSQRSQQINDAVG
PDASPQSRDAAALDTRKDKAVADPDLLIADWRDRLGKAGFELPLYLAKADERAQGYTVPTPAGTDITQAVSQAISILSDK
KVQFSYSELLAATVSQLPVEQGLITQAREGIEQAIGRERLIPLDKEKGIFTSDIHLLNELSIAQLANEFNKRPPIATFAE
RATPRDRPYANAYSVLAQDKAPLAILSGRGGMAQTIERMEDAVLMASEQGREVTILASDNRSARLLAQSQPLAGNIAPRH
TLNAATVFAPHSTLIVEQAESLTLKETLLILEKARASDVQVLMLDSERQRGVGNALSVLKQASVPQYRFYDAPNIEATVQ
SVPDKPARFDALAQDYAHRLQQGEQVVAQVSGTRDQQQLTSHIRSALRDIGQLHGQDHTLNVLAPVWLDSKTRHQRDTYR
EGMVMERWDDKGKTMDRYRIDLVADKTHSLVLANEQGEKHTIKIRALDSNWSLFESKRIEVAAGDTLRVLGREAEGTLKA
QQTLQVLDAAPGHLHLKTPTGELQLPTDRALKLDHNYVTGVGVTASQEATVLAAMSARQMSGTGLNQLARSGQHIHIYTP
LDQMRAQSKLASHPQFQLASEKLKAHGDSDQLDTTLKQATASLHTAAEQALHLGLAQVEAKGIVFSTSSLLAAALDFAPA
TPIDSISAVLDDKLAKGDLLPVPGKRGDVVSRASFDMEKFIIATIAQGKGTATPYLQQVPDPQLAGLTPGQAQSTRLILE
SNDQFIAIQGYAGVGKTTQFKAVLSALDTLPPEQRPTVVGIGPTHRAVHEMQSTGVKAQTLASFLSESRLQAMAGEQQDH
SRTLFLVDESSMIGNRDMAEFYQRVAASGARVVSSGDTAQLKAISSGAPFQLMQERSAVDVAVMKEIVRQRPELKPAIYS
LIDGNLTQSLAQREAVQPAVVPRDPANKPDAWTPDRSVIEAKNPAELVVKDYVSRTRLTRDNTMVIVHLNEVRHGINAAI
HQALFDKGELGPRQTSLTILDPVRIEENSLRSSEQVQKNALLGKVAVLNQHYYTISGIDPQAGTMTIKDNEGKVRLISNI
ENTAHDLAIYQPREIKVSEGDKIRFTRTVNEHGHVANSQWQVKRIEDNGAIVLHDGNNEKTVRPDQFKEDQHIDLGYAIT
AYGAQGASSTYAIELQAIKVVNRNLITLSSAYVPASRAKEHMQTYTDDKEGWINLLNKNLKSQVSTAHDALEGDQIKGQK
VADMLLGTASTMRSTALGRHVLKTHQLDEQQHMGKYIAPGKKYPTPHAAFPVWDNNGKPAGAAMVELQSHHQNKGPTLDS
EYRLVANERAEFIGLQRASNGETRIATSLVDGIIMAAKHPQSGILVSINGAPPPFNVNRMTGGKLVVSDTDAQHLQKESE
RELPLPQDMTTKESKRQDELIKTVAREKEHPDIKLPDDKQHAVNRDDKRLHNDINQLNKDAELSERQLRKLAEIGEVAKA
KFTHELHDKLDKLEREIIKELTKGE

Specific function: TraI has been identified as DNA helicase I and it also has an additional activity of site-specific nicking at oriT. DNA helicase I is a potent DNA-dependent ATPase [H]

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To traI of plasmid IncFII R100 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014059
- InterPro:   IPR014129
- InterPro:   IPR009767
- InterPro:   IPR014862 [H]

Pfam domain/function: PF07057 TraI; PF08751 TrwC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 186730; Mature: 186730

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLGSSAYYAAEENYYAMGDLESVWMGEGADRLGLSGPIDGATLDAIAQGKLPDGTELS
CCCCCCCEEEEECCCEEEECCCHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHH
RIVDGKQTHRTGYDLTFSAPKSVSVMALVAGDERFLAAHHHAVAVAMKEVEALASTRIMT
HHHCCCHHCCCCCEEEECCCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHC
DGITRTETTGNIVAALYTHDTSRELDPQLHTHSLVLNATYAEGKWRALSSDAAHMNSGFG
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCEEECCCCHHHHCCCCC
KDIFNNKLALGQIYRHALRQDVEAMGFETEVTGKHGLWELKGVPTEPFSQRSQQINDAVG
HHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHCC
PDASPQSRDAAALDTRKDKAVADPDLLIADWRDRLGKAGFELPLYLAKADERAQGYTVPT
CCCCCCCCCCHHHCCCCCCCCCCCCEEEEHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
PAGTDITQAVSQAISILSDKKVQFSYSELLAATVSQLPVEQGLITQAREGIEQAIGRERL
CCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
IPLDKEKGIFTSDIHLLNELSIAQLANEFNKRPPIATFAERATPRDRPYANAYSVLAQDK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHCCC
APLAILSGRGGMAQTIERMEDAVLMASEQGREVTILASDNRSARLLAQSQPLAGNIAPRH
CCEEEEECCCCHHHHHHHHHHHHEEECCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCC
TLNAATVFAPHSTLIVEQAESLTLKETLLILEKARASDVQVLMLDSERQRGVGNALSVLK
CCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCHHHHHHHH
QASVPQYRFYDAPNIEATVQSVPDKPARFDALAQDYAHRLQQGEQVVAQVSGTRDQQQLT
HCCCCCEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SHIRSALRDIGQLHGQDHTLNVLAPVWLDSKTRHQRDTYREGMVMERWDDKGKTMDRYRI
HHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHCCCEEEHHCCCCCCCCCEEE
DLVADKTHSLVLANEQGEKHTIKIRALDSNWSLFESKRIEVAAGDTLRVLGREAEGTLKA
EEEECCCCEEEEECCCCCEEEEEEEEECCCCCCHHCCEEEEECCCEEEEECCCCCCHHHH
QQTLQVLDAAPGHLHLKTPTGELQLPTDRALKLDHNYVTGVGVTASQEATVLAAMSARQM
HHHHHHHHCCCCEEEEECCCCCEECCCCCCEEECCCEEEECCCCCCCCCHHHHHHHHHHC
SGTGLNQLARSGQHIHIYTPLDQMRAQSKLASHPQFQLASEKLKAHGDSDQLDTTLKQAT
CCCCHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
ASLHTAAEQALHLGLAQVEAKGIVFSTSSLLAAALDFAPATPIDSISAVLDDKLAKGDLL
HHHHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEE
PVPGKRGDVVSRASFDMEKFIIATIAQGKGTATPYLQQVPDPQLAGLTPGQAQSTRLILE
CCCCCCCCCCHHHHCCHHHHHHHEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEE
SNDQFIAIQGYAGVGKTTQFKAVLSALDTLPPEQRPTVVGIGPTHRAVHEMQSTGVKAQT
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHH
LASFLSESRLQAMAGEQQDHSRTLFLVDESSMIGNRDMAEFYQRVAASGARVVSSGDTAQ
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCEE
LKAISSGAPFQLMQERSAVDVAVMKEIVRQRPELKPAIYSLIDGNLTQSLAQREAVQPAV
EEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCCCC
VPRDPANKPDAWTPDRSVIEAKNPAELVVKDYVSRTRLTRDNTMVIVHLNEVRHGINAAI
CCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHH
HQALFDKGELGPRQTSLTILDPVRIEENSLRSSEQVQKNALLGKVAVLNQHYYTISGIDP
HHHHHCCCCCCCCCCEEEEECCEEECHHHCCCHHHHHHHHHHHHHEEECCCEEEEECCCC
QAGTMTIKDNEGKVRLISNIENTAHDLAIYQPREIKVSEGDKIRFTRTVNEHGHVANSQW
CCCEEEEECCCCCEEEEECCCHHHHHEEEECCCEEEECCCCEEEEEEEECCCCCCCCCCE
QVKRIEDNGAIVLHDGNNEKTVRPDQFKEDQHIDLGYAITAYGAQGASSTYAIELQAIKV
EEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEEE
VNRNLITLSSAYVPASRAKEHMQTYTDDKEGWINLLNKNLKSQVSTAHDALEGDQIKGQK
CCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VADMLLGTASTMRSTALGRHVLKTHQLDEQQHMGKYIAPGKKYPTPHAAFPVWDNNGKPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCC
GAAMVELQSHHQNKGPTLDSEYRLVANERAEFIGLQRASNGETRIATSLVDGIIMAAKHP
CHHHHEEHHHCCCCCCCCCCCHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCC
QSGILVSINGAPPPFNVNRMTGGKLVVSDTDAQHLQKESERELPLPQDMTTKESKRQDEL
CCCEEEEECCCCCCCCCEEECCCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
IKTVAREKEHPDIKLPDDKQHAVNRDDKRLHNDINQLNKDAELSERQLRKLAEIGEVAKA
HHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KFTHELHDKLDKLEREIIKELTKGE
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSLGSSAYYAAEENYYAMGDLESVWMGEGADRLGLSGPIDGATLDAIAQGKLPDGTELS
CCCCCCCEEEEECCCEEEECCCHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHH
RIVDGKQTHRTGYDLTFSAPKSVSVMALVAGDERFLAAHHHAVAVAMKEVEALASTRIMT
HHHCCCHHCCCCCEEEECCCCCCEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHC
DGITRTETTGNIVAALYTHDTSRELDPQLHTHSLVLNATYAEGKWRALSSDAAHMNSGFG
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCEEECCCCHHHHCCCCC
KDIFNNKLALGQIYRHALRQDVEAMGFETEVTGKHGLWELKGVPTEPFSQRSQQINDAVG
HHHHCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCCCHHHHHHHHHHHHCC
PDASPQSRDAAALDTRKDKAVADPDLLIADWRDRLGKAGFELPLYLAKADERAQGYTVPT
CCCCCCCCCCHHHCCCCCCCCCCCCEEEEHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
PAGTDITQAVSQAISILSDKKVQFSYSELLAATVSQLPVEQGLITQAREGIEQAIGRERL
CCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
IPLDKEKGIFTSDIHLLNELSIAQLANEFNKRPPIATFAERATPRDRPYANAYSVLAQDK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHCCC
APLAILSGRGGMAQTIERMEDAVLMASEQGREVTILASDNRSARLLAQSQPLAGNIAPRH
CCEEEEECCCCHHHHHHHHHHHHEEECCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCC
TLNAATVFAPHSTLIVEQAESLTLKETLLILEKARASDVQVLMLDSERQRGVGNALSVLK
CCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHCCCHHHHHHHH
QASVPQYRFYDAPNIEATVQSVPDKPARFDALAQDYAHRLQQGEQVVAQVSGTRDQQQLT
HCCCCCEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SHIRSALRDIGQLHGQDHTLNVLAPVWLDSKTRHQRDTYREGMVMERWDDKGKTMDRYRI
HHHHHHHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHCCCEEEHHCCCCCCCCCEEE
DLVADKTHSLVLANEQGEKHTIKIRALDSNWSLFESKRIEVAAGDTLRVLGREAEGTLKA
EEEECCCCEEEEECCCCCEEEEEEEEECCCCCCHHCCEEEEECCCEEEEECCCCCCHHHH
QQTLQVLDAAPGHLHLKTPTGELQLPTDRALKLDHNYVTGVGVTASQEATVLAAMSARQM
HHHHHHHHCCCCEEEEECCCCCEECCCCCCEEECCCEEEECCCCCCCCCHHHHHHHHHHC
SGTGLNQLARSGQHIHIYTPLDQMRAQSKLASHPQFQLASEKLKAHGDSDQLDTTLKQAT
CCCCHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHH
ASLHTAAEQALHLGLAQVEAKGIVFSTSSLLAAALDFAPATPIDSISAVLDDKLAKGDLL
HHHHHHHHHHHHHHHHHEECCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEE
PVPGKRGDVVSRASFDMEKFIIATIAQGKGTATPYLQQVPDPQLAGLTPGQAQSTRLILE
CCCCCCCCCCHHHHCCHHHHHHHEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEE
SNDQFIAIQGYAGVGKTTQFKAVLSALDTLPPEQRPTVVGIGPTHRAVHEMQSTGVKAQT
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHCCCHHHH
LASFLSESRLQAMAGEQQDHSRTLFLVDESSMIGNRDMAEFYQRVAASGARVVSSGDTAQ
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCEE
LKAISSGAPFQLMQERSAVDVAVMKEIVRQRPELKPAIYSLIDGNLTQSLAQREAVQPAV
EEEECCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCCCC
VPRDPANKPDAWTPDRSVIEAKNPAELVVKDYVSRTRLTRDNTMVIVHLNEVRHGINAAI
CCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHH
HQALFDKGELGPRQTSLTILDPVRIEENSLRSSEQVQKNALLGKVAVLNQHYYTISGIDP
HHHHHCCCCCCCCCCEEEEECCEEECHHHCCCHHHHHHHHHHHHHEEECCCEEEEECCCC
QAGTMTIKDNEGKVRLISNIENTAHDLAIYQPREIKVSEGDKIRFTRTVNEHGHVANSQW
CCCEEEEECCCCCEEEEECCCHHHHHEEEECCCEEEECCCCEEEEEEEECCCCCCCCCCE
QVKRIEDNGAIVLHDGNNEKTVRPDQFKEDQHIDLGYAITAYGAQGASSTYAIELQAIKV
EEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEEEEEEE
VNRNLITLSSAYVPASRAKEHMQTYTDDKEGWINLLNKNLKSQVSTAHDALEGDQIKGQK
CCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
VADMLLGTASTMRSTALGRHVLKTHQLDEQQHMGKYIAPGKKYPTPHAAFPVWDNNGKPA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCC
GAAMVELQSHHQNKGPTLDSEYRLVANERAEFIGLQRASNGETRIATSLVDGIIMAAKHP
CHHHHEEHHHCCCCCCCCCCCHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCC
QSGILVSINGAPPPFNVNRMTGGKLVVSDTDAQHLQKESERELPLPQDMTTKESKRQDEL
CCCEEEEECCCCCCCCCEEECCCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
IKTVAREKEHPDIKLPDDKQHAVNRDDKRLHNDINQLNKDAELSERQLRKLAEIGEVAKA
HHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
KFTHELHDKLDKLEREIIKELTKGE
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2163400; 7915817; 2680768; 2164585; 8736534 [H]