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The map label for this gene is cobK [H]

Identifier: 159185388

GI number: 159185388

Start: 2800721

End: 2801503

Strand: Direct

Name: cobK [H]

Synonym: Atu2799

Alternate gene names: 159185388

Gene position: 2800721-2801503 (Clockwise)

Preceding gene: 159185386

Following gene: 159185391

Centisome position: 98.56

GC content: 61.81

Gene sequence:

>783_bases
ATGACACGCTCCATACTCATCCTTGGCGGCACGGCGGATGCCCGCATTCTGGCCGGCCGGCTGGCGGAAGACTCCGGCTA
CCGAATTCTGCTGTCCATGGCCGGGCGCACGCTCTCGCCGGTGGAACAGCCCGTGCCGATGCGCAGCGGCGGGTTTGGTG
GCGCGGCAGGACTGGCGGATTTCATTCGCGCAGAGGGTTTCGATATTCTCGTGGACGCCACTCATCCCTATGCGGCCAGA
ATTTCCGCCAATGCCGTCGAGGCGGCAAGGCTTGCCAATATACCACTGGTCGTGCTCTCGCGTCCCGTCTGGCCGCGTCA
GCCGGGTGACACATGGCAGAGCGTCCACACCGTCGGACAGGCCGTCACCGCGCTGGGCACTACGGGCAAACGTGTGTTTC
TGGCGCTTGGCCGTCAGGAGCTTCTTCCTTTCGAAGCAGCACCTCAGCACAGTTATCTCATCCGCAGCGTCGACCCGGTG
GAACCGCCGCTGAGGGCCCCGGATGCGCGCTATATCACCGCGCGTGGTCCTTTCGTAACGGAAGATGAAATCCGCATGCT
GGAGGAAAACCGCATCGAGGTGGTGATATCGAAAAACTCGGGCGGCAGCGCCAGTTACGGCAAGATCGAAGCAGCGAGAC
GGCTCGGCCTGCCGGTCATCATGATCGAACGGCCGCAACAATTGAACGATACGCCCGCGAATAATGTGACCGTGCCGGAT
ATCGCCACTGCGCTCACCGCCATACGCCATCAGCTTTCCCTTTTCGAAAACCGTGGCGAATAA

Upstream 100 bases:

>100_bases
CAGCCCCTGAAGCCCGTCCTCGCCTATACCGACAATGGACAGCCACGGCTTTTCGTTCTTTTCAGTGGAAGCCTTTGCCG
TTCCGGAATATTCAGATGTC

Downstream 100 bases:

>100_bases
ACGATCGGTTCCTTGCCGGAACGCGCGATCAGGCGGGTTTCCACCGAGCCGACGATGATGCAGGTGGCCATGTCGGCCAT
GTCGCTCGACGCCTCCGACA

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTRSILILGGTADARILAGRLAEDSGYRILLSMAGRTLSPVEQPVPMRSGGFGGAAGLADFIRAEGFDILVDATHPYAAR
ISANAVEAARLANIPLVVLSRPVWPRQPGDTWQSVHTVGQAVTALGTTGKRVFLALGRQELLPFEAAPQHSYLIRSVDPV
EPPLRAPDARYITARGPFVTEDEIRMLEENRIEVVISKNSGGSASYGKIEAARRLGLPVIMIERPQQLNDTPANNVTVPD
IATALTAIRHQLSLFENRGE

Sequences:

>Translated_260_residues
MTRSILILGGTADARILAGRLAEDSGYRILLSMAGRTLSPVEQPVPMRSGGFGGAAGLADFIRAEGFDILVDATHPYAAR
ISANAVEAARLANIPLVVLSRPVWPRQPGDTWQSVHTVGQAVTALGTTGKRVFLALGRQELLPFEAAPQHSYLIRSVDPV
EPPLRAPDARYITARGPFVTEDEIRMLEENRIEVVISKNSGGSASYGKIEAARRLGLPVIMIERPQQLNDTPANNVTVPD
IATALTAIRHQLSLFENRGE
>Mature_259_residues
TRSILILGGTADARILAGRLAEDSGYRILLSMAGRTLSPVEQPVPMRSGGFGGAAGLADFIRAEGFDILVDATHPYAARI
SANAVEAARLANIPLVVLSRPVWPRQPGDTWQSVHTVGQAVTALGTTGKRVFLALGRQELLPFEAAPQHSYLIRSVDPVE
PPLRAPDARYITARGPFVTEDEIRMLEENRIEVVISKNSGGSASYGKIEAARRLGLPVIMIERPQQLNDTPANNVTVPDI
ATALTAIRHQLSLFENRGE

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 28032; Mature: 27901

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSILILGGTADARILAGRLAEDSGYRILLSMAGRTLSPVEQPVPMRSGGFGGAAGLAD
CCCEEEEEECCCCCCHHHHCCCCCCCCEEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHH
FIRAEGFDILVDATHPYAARISANAVEAARLANIPLVVLSRPVWPRQPGDTWQSVHTVGQ
HHHCCCCEEEEECCCCCEEEEECCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHH
AVTALGTTGKRVFLALGRQELLPFEAAPQHSYLIRSVDPVEPPLRAPDARYITARGPFVT
HHHHHCCCCCEEEEEECHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCCC
EDEIRMLEENRIEVVISKNSGGSASYGKIEAARRLGLPVIMIERPQQLNDTPANNVTVPD
HHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCEECHH
IATALTAIRHQLSLFENRGE
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRSILILGGTADARILAGRLAEDSGYRILLSMAGRTLSPVEQPVPMRSGGFGGAAGLAD
CCEEEEEECCCCCCHHHHCCCCCCCCEEEEEECCCCCCCHHCCCCCCCCCCCCHHHHHH
FIRAEGFDILVDATHPYAARISANAVEAARLANIPLVVLSRPVWPRQPGDTWQSVHTVGQ
HHHCCCCEEEEECCCCCEEEEECCHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHH
AVTALGTTGKRVFLALGRQELLPFEAAPQHSYLIRSVDPVEPPLRAPDARYITARGPFVT
HHHHHCCCCCEEEEEECHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEECCCCCC
EDEIRMLEENRIEVVISKNSGGSASYGKIEAARRLGLPVIMIERPQQLNDTPANNVTVPD
HHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCEECHH
IATALTAIRHQLSLFENRGE
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]