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The map label for this gene is cobO [H]

Identifier: 159185391

GI number: 159185391

Start: 2810321

End: 2810938

Strand: Direct

Name: cobO [H]

Synonym: Atu2807

Alternate gene names: 159185391

Gene position: 2810321-2810938 (Clockwise)

Preceding gene: 159185388

Following gene: 15890055

Centisome position: 98.9

GC content: 61.0

Gene sequence:

>618_bases
ATGACCCGCGACATCAGCGACAGCGAAGCCGAACGCCACCGGCAGAAAATGGTCAACCGCAAGACTGTGCAGGACGCCGA
AGTTGCGGAAAAGACCATCGAAAAAGGCCTGCTGATGATCAATACCGGGCCCGGCAAGGGCAAGTCCACGGCCGCGTTCG
GCCTCGCCTTGCGCATGCTCGGCACCGGGCGGCGAGTTGGCGTCGTGCAATTCATCAAGGGTGCATGGTCGACGGGAGAG
CAGCAGGCCCTGACGCTCTTCGGGGATAAGGTCGTCTGGCGCACCATGGGGGAGGGCTTCACTTGGGACACGCAGGACCT
CAAACGCGATGTCGCGGCCGCGGCAAAGGCCTGGGAAGAGGCCAAGGCCCTGATGGCCGACCAAACAATCGGTCTTCTGC
TCCTCGACGAGCTGAACATCGCTTTGCGCTATGATTACCTGCCGCTGGAAGAAGTTGTCGAAACGCTCTCTAGTCGCAGG
CCCGATCTGCATGTCATCGTCACCGGCCGCAACGCCAAGCAGCCGCTGATCGACGCCGCCGATATGGTGACGGAAATGAC
GCTGGTGAAACATCACTTCAAGGCGGGCGTGAAGGCCCAAGCCGGGATAGAATTCTGA

Upstream 100 bases:

>100_bases
CGTGACCAGCGCATTGCCGGGTGCGGCAAATTGAGTATAGTCGCCGCTCCGAATGGCGGGGGCAAAAGGTCTCGCGCCGC
AGGACAAGAAGGAACGAGCG

Downstream 100 bases:

>100_bases
CATGACAGCACGGGTGCTGATGTTTCAGGGAACCGGCTCCGATGTCGGCAAATCGCTGATGGTGGCCGGTCTTGCCCGGG
CATTCACCCGGCGCGGCCTC

Product: cob(I)alamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MTRDISDSEAERHRQKMVNRKTVQDAEVAEKTIEKGLLMINTGPGKGKSTAAFGLALRMLGTGRRVGVVQFIKGAWSTGE
QQALTLFGDKVVWRTMGEGFTWDTQDLKRDVAAAAKAWEEAKALMADQTIGLLLLDELNIALRYDYLPLEEVVETLSSRR
PDLHVIVTGRNAKQPLIDAADMVTEMTLVKHHFKAGVKAQAGIEF

Sequences:

>Translated_205_residues
MTRDISDSEAERHRQKMVNRKTVQDAEVAEKTIEKGLLMINTGPGKGKSTAAFGLALRMLGTGRRVGVVQFIKGAWSTGE
QQALTLFGDKVVWRTMGEGFTWDTQDLKRDVAAAAKAWEEAKALMADQTIGLLLLDELNIALRYDYLPLEEVVETLSSRR
PDLHVIVTGRNAKQPLIDAADMVTEMTLVKHHFKAGVKAQAGIEF
>Mature_204_residues
TRDISDSEAERHRQKMVNRKTVQDAEVAEKTIEKGLLMINTGPGKGKSTAAFGLALRMLGTGRRVGVVQFIKGAWSTGEQ
QALTLFGDKVVWRTMGEGFTWDTQDLKRDVAAAAKAWEEAKALMADQTIGLLLLDELNIALRYDYLPLEEVVETLSSRRP
DLHVIVTGRNAKQPLIDAADMVTEMTLVKHHFKAGVKAQAGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=195, Percent_Identity=48.2051282051282, Blast_Score=188, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 22680; Mature: 22549

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRDISDSEAERHRQKMVNRKTVQDAEVAEKTIEKGLLMINTGPGKGKSTAAFGLALRML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHH
GTGRRVGVVQFIKGAWSTGEQQALTLFGDKVVWRTMGEGFTWDTQDLKRDVAAAAKAWEE
CCCCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AKALMADQTIGLLLLDELNIALRYDYLPLEEVVETLSSRRPDLHVIVTGRNAKQPLIDAA
HHHHHHHCHHHEEEEECCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
DMVTEMTLVKHHFKAGVKAQAGIEF
HHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TRDISDSEAERHRQKMVNRKTVQDAEVAEKTIEKGLLMINTGPGKGKSTAAFGLALRML
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHH
GTGRRVGVVQFIKGAWSTGEQQALTLFGDKVVWRTMGEGFTWDTQDLKRDVAAAAKAWEE
CCCCCHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AKALMADQTIGLLLLDELNIALRYDYLPLEEVVETLSSRRPDLHVIVTGRNAKQPLIDAA
HHHHHHHCHHHEEEEECCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHH
DMVTEMTLVKHHFKAGVKAQAGIEF
HHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]