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The map label for this gene is ttuB [H]

Identifier: 159185338

GI number: 159185338

Start: 2691891

End: 2693168

Strand: Reverse

Name: ttuB [H]

Synonym: Atu2708

Alternate gene names: 159185338

Gene position: 2693168-2691891 (Counterclockwise)

Preceding gene: 159185340

Following gene: 159185335

Centisome position: 94.78

GC content: 57.36

Gene sequence:

>1278_bases
ATGGTATCCGAAAAGGCCCTCATATCGAAGATCACCTGGCGGCTGATGCCGTTTCTTGGCCTTCTCTACCTCATCGCTTA
TATTGACCGCCAGAATGTCAGCTATGCCAAGCTGCAGATGGTCGATGCGCTGAGCCTGAGCGAATATGCCTACGGTCTTG
GCGCTTCGCTGTTTTTCATCGGTTATTTCCTCTTCGAAGTGCCGAGCAACCTGTTCCTCAACCGTTTCGGCGCCAGCAAA
TGGTTTGCCCGCATTCTGGTTTCCTGGGGCGCCGTCACCATCGCGCTTGCCTATACGCAGAACGCCACGATGTTTTACAT
CCTGCGTTTCCTGCTCGGGCTTTGCGAGGCGGGCTTCTTCCCCGGCGTGCTGTTCCTCATGACGCTCTGGTTCCCGCGTG
ATTATCGCGGTCGCATGATCGGCCTCTTCATGATTTTCAGCGCGCTTGCCAACGCAGTCGGTGCGCCGCTCGGCGGCATG
CTGCTCGATCTCGATGGTTTCCTCGGTTATGCCGGATGGGAATGGGTTTTCCTGGCGACCGGCATACCTGCCGTCATCGC
CGGCATCGTAACCTTCTTTTATCTGGATGACACGCCTGATAAGGCGAAGTTCCTCACCCAGGATGAGAAGGACTGGCTGA
AGAACCGGCTGGCCGAAGAAAACAAGGGCATGGAAGAACATGCGGAAGACGGTTTCAAGGCCCTGGTCAACCCGCGCGTT
CTGTTCATGGCGCTGTGCTACGTCGGATTTCCGCTGGCTGCTTATGGGCTTAGCTACTGGCTTCCGACGATCGTGAAGAG
TTTTGGTGTTTCCAACACCACCAACGGCTTCATCAATATCATCCCCTGGATTATCGTCGCCATTGCCCTGTTCGTCGTGC
CTTCCGCGGCCGACAAGGCGAAGAACAAGACGCCCTATATTGTTGGTCCGGCTTTCGTTGGCGCTTTCTGCCTGCTGATG
TCGGCATTGCTCAGCGATCCGGTGTTGCAGTTCGCCTTCCTTTGTGTCGCTGCCGCAGGTATCTTCGCCGGCCAGCCGGT
GTTCTGGAGCCTGCCCGGCCGTTTCCTCAAGGGAGCGGGTGCGGCTGCGGGTATCGCCGCGATCAATTCCGTCGGCAATC
TCGGTGGCTTCGTGGCGCAGAATGTCGTGCCCTGGATCAAGGATCAAACCGGCAGCACGATCGCGCCGATGTTCTTCCTT
GCGTTCTGCCTTGCGCTTGCAGGGGTGCTCGTCATCATCGCAACGCGTAAAATGGGCAATCAGGTCAAGGCTGCCTGA

Upstream 100 bases:

>100_bases
GATCGATATGGTGCGACGCAACTTGCCTATTTTGCGGCGCACATATAGATGGGTTCCCTTATCATTTGCATTCGACGAGA
AATCGAAGGGAGGAAAGCAC

Downstream 100 bases:

>100_bases
CTTTGGAAGATTGAGACAGCTGACGCGATTACTCACAGTTGCACATATAAAAATTGTGGCCCGGAGGTTTCCGGGCCACA
ATCATTTTAAGCGATAGAAT

Product: MFS permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MVSEKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIGYFLFEVPSNLFLNRFGASK
WFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPGVLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGM
LLDLDGFLGYAGWEWVFLATGIPAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLAEENKGMEEHAEDGFKALVNPRV
LFMALCYVGFPLAAYGLSYWLPTIVKSFGVSNTTNGFINIIPWIIVAIALFVVPSAADKAKNKTPYIVGPAFVGAFCLLM
SALLSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAGAAAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFL
AFCLALAGVLVIIATRKMGNQVKAA

Sequences:

>Translated_425_residues
MVSEKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIGYFLFEVPSNLFLNRFGASK
WFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPGVLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGM
LLDLDGFLGYAGWEWVFLATGIPAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLAEENKGMEEHAEDGFKALVNPRV
LFMALCYVGFPLAAYGLSYWLPTIVKSFGVSNTTNGFINIIPWIIVAIALFVVPSAADKAKNKTPYIVGPAFVGAFCLLM
SALLSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAGAAAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFL
AFCLALAGVLVIIATRKMGNQVKAA
>Mature_425_residues
MVSEKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFIGYFLFEVPSNLFLNRFGASK
WFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFFPGVLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGM
LLDLDGFLGYAGWEWVFLATGIPAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLAEENKGMEEHAEDGFKALVNPRV
LFMALCYVGFPLAAYGLSYWLPTIVKSFGVSNTTNGFINIIPWIIVAIALFVVPSAADKAKNKTPYIVGPAFVGAFCLLM
SALLSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAGAAAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFL
AFCLALAGVLVIIATRKMGNQVKAA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=417, Percent_Identity=38.1294964028777, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI87082320, Length=419, Percent_Identity=22.9116945107399, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI2367379, Length=432, Percent_Identity=22.9166666666667, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789515, Length=252, Percent_Identity=23.8095238095238, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789152, Length=277, Percent_Identity=24.5487364620939, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569727, Length=189, Percent_Identity=25.3968253968254, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=312, Percent_Identity=22.1153846153846, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323032, Length=225, Percent_Identity=27.1111111111111, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322025, Length=231, Percent_Identity=23.8095238095238, Blast_Score=76, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6322612, Length=279, Percent_Identity=24.0143369175627, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=236, Percent_Identity=23.3050847457627, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319876, Length=238, Percent_Identity=24.7899159663866, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46374; Mature: 46374

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSEKALISKITWRLMPFLGLLYLIAYIDRQNVSYAKLQMVDALSLSEYAYGLGASLFFI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GYFLFEVPSNLFLNRFGASKWFARILVSWGAVTIALAYTQNATMFYILRFLLGLCEAGFF
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCH
PGVLFLMTLWFPRDYRGRMIGLFMIFSALANAVGAPLGGMLLDLDGFLGYAGWEWVFLAT
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHEEHHHHHCCCCHHHHHHHC
GIPAVIAGIVTFFYLDDTPDKAKFLTQDEKDWLKNRLAEENKGMEEHAEDGFKALVNPRV
CHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHH
LFMALCYVGFPLAAYGLSYWLPTIVKSFGVSNTTNGFINIIPWIIVAIALFVVPSAADKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
KNKTPYIVGPAFVGAFCLLMSALLSDPVLQFAFLCVAAAGIFAGQPVFWSLPGRFLKGAG
CCCCCEEECHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHCCC
AAAGIAAINSVGNLGGFVAQNVVPWIKDQTGSTIAPMFFLAFCLALAGVLVIIATRKMGN
HHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QVKAA
CCCCC
>Mature Secondary Structure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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]