Click here to switch to the map view.

The map label for this gene is phhB

Identifier: 159185322

GI number: 159185322

Start: 2659960

End: 2660265

Strand: Reverse

Name: phhB

Synonym: Atu2676

Alternate gene names: NA

Gene position: 2660265-2659960 (Counterclockwise)

Preceding gene: 159185324

Following gene: 159185321

Centisome position: 93.62

GC content: 56.86

Gene sequence:

>306_bases
ATGAAATATCCCAGACTCGAACCGGACGCCATCCGGCAGGCATTGTCGAAACTCGAGGGCTGGTCGCTGCGTGAGGATGG
GGCGGCGATCGTTCGCTCCTTCAAGTTTTCGAGTTTTGCCGAAGCCTTCGGTTTCATGGCCGAGTCTGCTCTTGCGGCGG
AAAAGCTCAATCATCATCCGGAATGGTCAAACGTCTATTCGCGCGTGAAAGTCTGCCTTACCACCCATGATTCACAGGGT
GTGACCGAGCGGGATTTCCTTCTGGCCGAAGCTATGCAGAAGGCGGCTGCGGGCCGGGGGAATTGA

Upstream 100 bases:

>100_bases
ATATTGCCCATGCAGACGAAAAGAACGGTGATATGTTTCATGAACGATGCGTCGATCCGGTCGTTGAGGCGTTAGTGGTT
ATCAAACGGAGGCAAGATTC

Downstream 100 bases:

>100_bases
ACGACAGGCGTTTAATCCCATATAATAACCGTGACCGGAGGACCGTCGATCATGGATGATGTGAAAATCGGTGAAATTCT
TCTGCCGGGTGAAACCGACA

Product: pterin-4-alpha-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MKYPRLEPDAIRQALSKLEGWSLREDGAAIVRSFKFSSFAEAFGFMAESALAAEKLNHHPEWSNVYSRVKVCLTTHDSQG
VTERDFLLAEAMQKAAAGRGN

Sequences:

>Translated_101_residues
MKYPRLEPDAIRQALSKLEGWSLREDGAAIVRSFKFSSFAEAFGFMAESALAAEKLNHHPEWSNVYSRVKVCLTTHDSQG
VTERDFLLAEAMQKAAAGRGN
>Mature_101_residues
MKYPRLEPDAIRQALSKLEGWSLREDGAAIVRSFKFSSFAEAFGFMAESALAAEKLNHHPEWSNVYSRVKVCLTTHDSQG
VTERDFLLAEAMQKAAAGRGN

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI134133240, Length=95, Percent_Identity=47.3684210526316, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI4557831, Length=98, Percent_Identity=44.8979591836735, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI115533705, Length=94, Percent_Identity=44.6808510638298, Blast_Score=83, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45549100, Length=77, Percent_Identity=45.4545454545455, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_AGRT5 (Q8UC22)

Other databases:

- EMBL:   AE007869
- PIR:   AC2905
- RefSeq:   NP_530556.1
- ProteinModelPortal:   Q8UC22
- SMR:   Q8UC22
- STRING:   Q8UC22
- GeneID:   1134714
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2676
- NMPDR:   fig|176299.3.peg.1906
- eggNOG:   COG2154
- HOGENOM:   HBG705804
- OMA:   FNVYSRV
- ProtClustDB:   PRK00823
- BioCyc:   ATUM176299-1:ATU2676-MONOMER
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 11247; Mature: 11247

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYPRLEPDAIRQALSKLEGWSLREDGAAIVRSFKFSSFAEAFGFMAESALAAEKLNHHP
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EWSNVYSRVKVCLTTHDSQGVTERDFLLAEAMQKAAAGRGN
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKYPRLEPDAIRQALSKLEGWSLREDGAAIVRSFKFSSFAEAFGFMAESALAAEKLNHHP
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EWSNVYSRVKVCLTTHDSQGVTERDFLLAEAMQKAAAGRGN
CHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194