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The map label for this gene is tctD [H]

Identifier: 159185227

GI number: 159185227

Start: 2435578

End: 2436258

Strand: Reverse

Name: tctD [H]

Synonym: Atu2466

Alternate gene names: 159185227

Gene position: 2436258-2435578 (Counterclockwise)

Preceding gene: 159185229

Following gene: 15889736

Centisome position: 85.74

GC content: 62.11

Gene sequence:

>681_bases
TTGCGTATTTTGCTGGTCGAGGACAATCAGGTGCTGTCGGAAGGGCTTTCAGCCCTTCTGCGCGGCAGTGGTTATGCGGT
TGATGTCGTTTCAGACGGCGCCTCGGCCGATGCGGCGATTGCGGCGGAAAGTTTCGACCTCGTCATTCTCGATCTCAACC
TGCCGGAAATGGACGGTATCGAGGTGCTGCGCTCCATGCGCTCGCGCCAAGATAAGGCGGCGGTACTGATCCTGACGGCG
CGCGGCACGCCGGAGGAGAAGGTCAAGGGGCTCGATCTCGGCGCCGACGACTACATGATCAAGCCGTTCGACATCACCGA
ATTCGAGGCAAGGGTGCGGGTGCTCTTGCGCCGCAACGCCGGCCTGCGGTCCTCCGCGCTTAGTTTCGGCAAGGTGCTGT
TCGATCTGACGTCGCGCACCTTTTCGGCCGATGGGCGCCCGCTCGATATTCCGGCACGCGAGGTGGCGCTGCTCGAAGTG
CTGTTCATGCGGGCGGGCAAGGTGGTCGCCAAGGAGGCGATCGTGCAGTCGCTCACAGGTTTCGACGACGATATTTCCGC
CAACGCCATCGAGCAATATGTCAGCCGCCTGCGCAAGCGGCTCGCTCCCCACGGGCTGACGGTGAAGACGGCGCGCGGCA
TCGGTTATTATCTGGAAAAGCTGCCGGAGATGGCTGAATGA

Upstream 100 bases:

>100_bases
AGAAAAAGGCAGATACGCATGGAAAAGATCATGCCGCAGGCGCTTGCCATTCACAAGCGGGCAGGGCTTGGCTAAATTAG
GATATTGTGGAGGGGAAAAT

Downstream 100 bases:

>100_bases
GACAGGCCGCCTATTCGCTCAGGCGGCGACTGTTAGGCTGGCTTCTCATCTCCACAGCTATCATTGGCTGCGTTGCGCTG
ACCGACACCTGGCGCGAGGC

Product: two component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRILLVEDNQVLSEGLSALLRGSGYAVDVVSDGASADAAIAAESFDLVILDLNLPEMDGIEVLRSMRSRQDKAAVLILTA
RGTPEEKVKGLDLGADDYMIKPFDITEFEARVRVLLRRNAGLRSSALSFGKVLFDLTSRTFSADGRPLDIPAREVALLEV
LFMRAGKVVAKEAIVQSLTGFDDDISANAIEQYVSRLRKRLAPHGLTVKTARGIGYYLEKLPEMAE

Sequences:

>Translated_226_residues
MRILLVEDNQVLSEGLSALLRGSGYAVDVVSDGASADAAIAAESFDLVILDLNLPEMDGIEVLRSMRSRQDKAAVLILTA
RGTPEEKVKGLDLGADDYMIKPFDITEFEARVRVLLRRNAGLRSSALSFGKVLFDLTSRTFSADGRPLDIPAREVALLEV
LFMRAGKVVAKEAIVQSLTGFDDDISANAIEQYVSRLRKRLAPHGLTVKTARGIGYYLEKLPEMAE
>Mature_226_residues
MRILLVEDNQVLSEGLSALLRGSGYAVDVVSDGASADAAIAAESFDLVILDLNLPEMDGIEVLRSMRSRQDKAAVLILTA
RGTPEEKVKGLDLGADDYMIKPFDITEFEARVRVLLRRNAGLRSSALSFGKVLFDLTSRTFSADGRPLDIPAREVALLEV
LFMRAGKVVAKEAIVQSLTGFDDDISANAIEQYVSRLRKRLAPHGLTVKTARGIGYYLEKLPEMAE

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=40.8256880733945, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=37.6146788990826, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=36.6071428571429, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=36.0730593607306, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=36.036036036036, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=29.7777777777778, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=31.3636363636364, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=33.4841628959276, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=31.25, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=33.4763948497854, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=27.1111111111111, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=29.3617021276596, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=31.1111111111111, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=37.3831775700935, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790437, Length=108, Percent_Identity=39.8148148148148, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.82096069869, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=32.3809523809524, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1787487, Length=101, Percent_Identity=32.6732673267327, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=158, Percent_Identity=27.8481012658228, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24684; Mature: 24684

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDNQVLSEGLSALLRGSGYAVDVVSDGASADAAIAAESFDLVILDLNLPEMDGI
CEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCCEEEEECCCCCCCHH
EVLRSMRSRQDKAAVLILTARGTPEEKVKGLDLGADDYMIKPFDITEFEARVRVLLRRNA
HHHHHHHCCCCCEEEEEEEECCCCHHHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCC
GLRSSALSFGKVLFDLTSRTFSADGRPLDIPAREVALLEVLFMRAGKVVAKEAIVQSLTG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
FDDDISANAIEQYVSRLRKRLAPHGLTVKTARGIGYYLEKLPEMAE
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRILLVEDNQVLSEGLSALLRGSGYAVDVVSDGASADAAIAAESFDLVILDLNLPEMDGI
CEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCCEEEEECCCCCCCHH
EVLRSMRSRQDKAAVLILTARGTPEEKVKGLDLGADDYMIKPFDITEFEARVRVLLRRNA
HHHHHHHCCCCCEEEEEEEECCCCHHHHCCCCCCCCCCEECCCCCHHHHHHHHHHHHHCC
GLRSSALSFGKVLFDLTSRTFSADGRPLDIPAREVALLEVLFMRAGKVVAKEAIVQSLTG
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHC
FDDDISANAIEQYVSRLRKRLAPHGLTVKTARGIGYYLEKLPEMAE
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]