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The map label for this gene is glnA [H]

Identifier: 159185208

GI number: 159185208

Start: 2386484

End: 2387518

Strand: Direct

Name: glnA [H]

Synonym: Atu2416

Alternate gene names: 159185208

Gene position: 2386484-2387518 (Clockwise)

Preceding gene: 159185192

Following gene: 15889687

Centisome position: 83.98

GC content: 59.61

Gene sequence:

>1035_bases
ATGACTAAGTTCAAACTCGAGTACATCTGGCTGGACGGATACAAGCCGGTCGCAAACCTGCGCGGCAAGACACAGATCAA
GGAATTCGATGAATTCCCCACACTCGAGCAGTTGCCGCTTTGGGGTTTTGACGGCTCCTCCACCCAGCAGGCCGAAGGCC
ACTCATCGGATTGCGTGCTGAAGCCCGTTGCGATCTACCCGGATCCGGCCCGCACCAACGGCGCGCTCGTCATGTGCGAA
GTCATGATGCCCGATGGCGTCACCCCGCACGCTTCCAACAGCCGCGCCACGATCCTCGAAGACGAAGACGCATGGTTCGG
TTTCGAACAGGAATATTTCTTCTACCAGGACGGCCGCCCGCTCGGTTTCCCGGAACAGGGTTACCCCGCTCCGCAGGGTC
CGTATTACACCGGCGTCGGCTTCAAGAACGTCGGCTCGGTTGCCCGCGAAATCGTTGAAGAGCACCTCGATCTCTGCCTC
GAAGCCGGCATCAACCATGAAGGCATCAACGCCGAAGTGGCCAAGGGCCAGTGGGAATTCCAGGTATTCGGCAAGGGCTC
CAAGCGCGCCGCCGACCAGATCTGGATCGCCCGTTACCTGCTGCTGCGTCTTTGCGAACAGTACGGCATCGACGTCGAGT
TCCATTGCAAGCCGCTCGGCGATACCGACTGGAACGGCTCCGGCATGCATTGCAACTTCTCGACCAAGTTCATGCGCGAA
GTTGGCGGCAAGGACTATTTCGAAGCCCTCATGGCCGCTTTCGCCAAGAATTGGCAGGAGCACATCGACGTTTACGGTCC
GGACAACCATCTGCGCCTGACCGGCAAGCACGAAACCGCTCCGTGGAACAAGTTCTCCTATGGCGTGGCAGACCGTGGCG
CCTCGATCCGCGTTCCGCACTCCTTCGTCAACAACGGTTACCGTGGTTACCTCGAAGACCGTCGTCCGAATTCGCAGGGC
TGCCCCTACCAGATCGCTTCCGTCGTTCTGAAGACGATCGCAGAAGTGCCGCTCGCAAAGTCGGCTGCTGCCTGA

Upstream 100 bases:

>100_bases
ATGCATCTAAGGGGTCAGCCCTTGAACGCGAATGTGCTTCCGGTGGCAAAAGCCACGGCAAGCCTCAAGGCTTCGCATTG
TTACCTATGAGAGGTTCGTA

Downstream 100 bases:

>100_bases
TAACTTAAGGCATGGCGTCGCCCGCAACCGGGCGACGCCATTTTTATGTCCATCGAACGGCTGGGCCGGACACGCGACCT
TTTCGCCCTCTGCCCGCCCG

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase II; Glutamine synthetase II; GSII [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTKFKLEYIWLDGYKPVANLRGKTQIKEFDEFPTLEQLPLWGFDGSSTQQAEGHSSDCVLKPVAIYPDPARTNGALVMCE
VMMPDGVTPHASNSRATILEDEDAWFGFEQEYFFYQDGRPLGFPEQGYPAPQGPYYTGVGFKNVGSVAREIVEEHLDLCL
EAGINHEGINAEVAKGQWEFQVFGKGSKRAADQIWIARYLLLRLCEQYGIDVEFHCKPLGDTDWNGSGMHCNFSTKFMRE
VGGKDYFEALMAAFAKNWQEHIDVYGPDNHLRLTGKHETAPWNKFSYGVADRGASIRVPHSFVNNGYRGYLEDRRPNSQG
CPYQIASVVLKTIAEVPLAKSAAA

Sequences:

>Translated_344_residues
MTKFKLEYIWLDGYKPVANLRGKTQIKEFDEFPTLEQLPLWGFDGSSTQQAEGHSSDCVLKPVAIYPDPARTNGALVMCE
VMMPDGVTPHASNSRATILEDEDAWFGFEQEYFFYQDGRPLGFPEQGYPAPQGPYYTGVGFKNVGSVAREIVEEHLDLCL
EAGINHEGINAEVAKGQWEFQVFGKGSKRAADQIWIARYLLLRLCEQYGIDVEFHCKPLGDTDWNGSGMHCNFSTKFMRE
VGGKDYFEALMAAFAKNWQEHIDVYGPDNHLRLTGKHETAPWNKFSYGVADRGASIRVPHSFVNNGYRGYLEDRRPNSQG
CPYQIASVVLKTIAEVPLAKSAAA
>Mature_343_residues
TKFKLEYIWLDGYKPVANLRGKTQIKEFDEFPTLEQLPLWGFDGSSTQQAEGHSSDCVLKPVAIYPDPARTNGALVMCEV
MMPDGVTPHASNSRATILEDEDAWFGFEQEYFFYQDGRPLGFPEQGYPAPQGPYYTGVGFKNVGSVAREIVEEHLDLCLE
AGINHEGINAEVAKGQWEFQVFGKGSKRAADQIWIARYLLLRLCEQYGIDVEFHCKPLGDTDWNGSGMHCNFSTKFMREV
GGKDYFEALMAAFAKNWQEHIDVYGPDNHLRLTGKHETAPWNKFSYGVADRGASIRVPHSFVNNGYRGYLEDRRPNSQGC
PYQIASVVLKTIAEVPLAKSAAA

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI74271826, Length=342, Percent_Identity=43.2748538011696, Blast_Score=257, Evalue=9e-69,
Organism=Homo sapiens, GI74271837, Length=342, Percent_Identity=43.2748538011696, Blast_Score=257, Evalue=9e-69,
Organism=Homo sapiens, GI19923206, Length=342, Percent_Identity=43.2748538011696, Blast_Score=257, Evalue=9e-69,
Organism=Caenorhabditis elegans, GI115532978, Length=344, Percent_Identity=48.546511627907, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI115532980, Length=344, Percent_Identity=48.546511627907, Blast_Score=290, Evalue=6e-79,
Organism=Caenorhabditis elegans, GI17554028, Length=346, Percent_Identity=45.0867052023121, Blast_Score=271, Evalue=3e-73,
Organism=Caenorhabditis elegans, GI17538856, Length=346, Percent_Identity=43.3526011560694, Blast_Score=265, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17540008, Length=344, Percent_Identity=44.1860465116279, Blast_Score=265, Evalue=4e-71,
Organism=Caenorhabditis elegans, GI17551038, Length=317, Percent_Identity=39.1167192429022, Blast_Score=211, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6325292, Length=334, Percent_Identity=48.2035928143713, Blast_Score=293, Evalue=3e-80,
Organism=Drosophila melanogaster, GI281360453, Length=344, Percent_Identity=45.3488372093023, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI17136208, Length=344, Percent_Identity=45.3488372093023, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24580558, Length=344, Percent_Identity=45.3488372093023, Blast_Score=286, Evalue=2e-77,
Organism=Drosophila melanogaster, GI24641292, Length=340, Percent_Identity=48.2352941176471, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24641290, Length=340, Percent_Identity=48.2352941176471, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI45554830, Length=268, Percent_Identity=48.5074626865672, Blast_Score=228, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 38616; Mature: 38485

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKFKLEYIWLDGYKPVANLRGKTQIKEFDEFPTLEQLPLWGFDGSSTQQAEGHSSDCVL
CCEEEEEEEEECCCCHHHHCCCCHHHHHHHCCCCHHHCEEECCCCCCCCCCCCCCCCEEE
KPVAIYPDPARTNGALVMCEVMMPDGVTPHASNSRATILEDEDAWFGFEQEYFFYQDGRP
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCC
LGFPEQGYPAPQGPYYTGVGFKNVGSVAREIVEEHLDLCLEAGINHEGINAEVAKGQWEF
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEEE
QVFGKGSKRAADQIWIARYLLLRLCEQYGIDVEFHCKPLGDTDWNGSGMHCNFSTKFMRE
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCHHHHHHH
VGGKDYFEALMAAFAKNWQEHIDVYGPDNHLRLTGKHETAPWNKFSYGVADRGASIRVPH
CCCHHHHHHHHHHHHHCHHHHCEEECCCCCEEEECCCCCCCCCCEECCCCCCCCEEECCH
SFVNNGYRGYLEDRRPNSQGCPYQIASVVLKTIAEVPLAKSAAA
HHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TKFKLEYIWLDGYKPVANLRGKTQIKEFDEFPTLEQLPLWGFDGSSTQQAEGHSSDCVL
CEEEEEEEEECCCCHHHHCCCCHHHHHHHCCCCHHHCEEECCCCCCCCCCCCCCCCEEE
KPVAIYPDPARTNGALVMCEVMMPDGVTPHASNSRATILEDEDAWFGFEQEYFFYQDGRP
EEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCC
LGFPEQGYPAPQGPYYTGVGFKNVGSVAREIVEEHLDLCLEAGINHEGINAEVAKGQWEF
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEEEE
QVFGKGSKRAADQIWIARYLLLRLCEQYGIDVEFHCKPLGDTDWNGSGMHCNFSTKFMRE
EEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEECCHHHHHHH
VGGKDYFEALMAAFAKNWQEHIDVYGPDNHLRLTGKHETAPWNKFSYGVADRGASIRVPH
CCCHHHHHHHHHHHHHCHHHHCEEECCCCCEEEECCCCCCCCCCEECCCCCCCCEEECCH
SFVNNGYRGYLEDRRPNSQGCPYQIASVVLKTIAEVPLAKSAAA
HHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]