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The map label for this gene is trxB [H]

Identifier: 159185092

GI number: 159185092

Start: 2161161

End: 2162135

Strand: Direct

Name: trxB [H]

Synonym: Atu2185

Alternate gene names: 159185092

Gene position: 2161161-2162135 (Clockwise)

Preceding gene: 15889463

Following gene: 15889466

Centisome position: 76.05

GC content: 61.23

Gene sequence:

>975_bases
ATGTCTGCCCGCCACACGAAGGTATTGATCATTGGCTCCGGTCCCGCCGGCTATACCGCGGCGATCTACGCGGCCCGCGC
AATGCTGAAACCCGTGCTGATTGCCGGCATGGAACAGGGTGGCCAGCTGATGATCACCACCGATGTTGAAAACTACCCGG
GCTTCGCCGATCCGATCCAGGGCCCGTGGCTGATGGACCAGATGCTGAAGCAGGCAACCCATGTGGGCGCGGAAATCGTC
AGCGACCTCGTCACCGAAGTTGAGACCAACGTGCGGCCTTTCGTGGTCAGGACCGATTCGGGTCAGGTCTGGACCGCCGA
CACGCTAATCATCGCAACCGGTGCCAAGGCCAAATGGCTCGGCATCGAGAGCGAGCAGCACTTCCAGGGCTTCGGCGTCT
CCGCCTGCGCCACCTGCGACGGGTTTTTCTATCGCAACAAGGATGTGATCGTGGTCGGCGGCGGCAACTCCGCCGTGGAA
GAGGCGCTTTATCTCGCGCATATCGCCAAATCGGTCACCGTCGTGCACCGCCGCGACAGCTTCCGCTCGGAAAAAATCCT
GCAGGAACGGCTGTTTGCCAAGGAAAACGTCAAGATTCTCTGGAATACGGAAATTGCCGAAATCACCGGCGCACCGGCAA
AGCCGCCGATGCCGCCTTCCGTTTCCGGCGTCAGGCTGCGTGACACCAAGACTGGTGCGATCAGCGATACGCCCATTGAT
GGCGTTTTTGTCGCCATCGGCCACGCCCCGGCGGTCGAACTGTTCAAGGGCAAGGTGAAGCTCAAGGATAACGGCTACAT
GTGGACTGCTCCTGATTCCACGGCCACCGACGTGGAAGGCATCTTCGCCGCCGGCGACGTCACCGACGACATTTACCGCC
AGGCAATCACCGCCGCCGGCATGGGCTGCATGGCCGCCCTCGAAGCAGAACGCTATCTCACGGCGCAACAACCGCTCGCG
GTTGCAGCGGAATAA

Upstream 100 bases:

>100_bases
TTAAATACCGGGCAACGAAGGGGTTGCGGCCTATCCGCCGTCTTGCGGCTGGATGGCTTTGCCGCCGAAAGGCCCCGCTG
CTGAAAAAAGGAATATTTCC

Downstream 100 bases:

>100_bases
CCGAAAGGCAGGATAGGCATGGCAATGCCATTGGACTGGGATAAACTGCGCATTTTTCATGCCGCAGCCGAAGCGGGGTC
TTTTACCCACGCTGCCGACA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSARHTKVLIIGSGPAGYTAAIYAARAMLKPVLIAGMEQGGQLMITTDVENYPGFADPIQGPWLMDQMLKQATHVGAEIV
SDLVTEVETNVRPFVVRTDSGQVWTADTLIIATGAKAKWLGIESEQHFQGFGVSACATCDGFFYRNKDVIVVGGGNSAVE
EALYLAHIAKSVTVVHRRDSFRSEKILQERLFAKENVKILWNTEIAEITGAPAKPPMPPSVSGVRLRDTKTGAISDTPID
GVFVAIGHAPAVELFKGKVKLKDNGYMWTAPDSTATDVEGIFAAGDVTDDIYRQAITAAGMGCMAALEAERYLTAQQPLA
VAAE

Sequences:

>Translated_324_residues
MSARHTKVLIIGSGPAGYTAAIYAARAMLKPVLIAGMEQGGQLMITTDVENYPGFADPIQGPWLMDQMLKQATHVGAEIV
SDLVTEVETNVRPFVVRTDSGQVWTADTLIIATGAKAKWLGIESEQHFQGFGVSACATCDGFFYRNKDVIVVGGGNSAVE
EALYLAHIAKSVTVVHRRDSFRSEKILQERLFAKENVKILWNTEIAEITGAPAKPPMPPSVSGVRLRDTKTGAISDTPID
GVFVAIGHAPAVELFKGKVKLKDNGYMWTAPDSTATDVEGIFAAGDVTDDIYRQAITAAGMGCMAALEAERYLTAQQPLA
VAAE
>Mature_323_residues
SARHTKVLIIGSGPAGYTAAIYAARAMLKPVLIAGMEQGGQLMITTDVENYPGFADPIQGPWLMDQMLKQATHVGAEIVS
DLVTEVETNVRPFVVRTDSGQVWTADTLIIATGAKAKWLGIESEQHFQGFGVSACATCDGFFYRNKDVIVVGGGNSAVEE
ALYLAHIAKSVTVVHRRDSFRSEKILQERLFAKENVKILWNTEIAEITGAPAKPPMPPSVSGVRLRDTKTGAISDTPIDG
VFVAIGHAPAVELFKGKVKLKDNGYMWTAPDSTATDVEGIFAAGDVTDDIYRQAITAAGMGCMAALEAERYLTAQQPLAV
AAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=320, Percent_Identity=54.6875, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=36.1904761904762, Blast_Score=148, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321898, Length=323, Percent_Identity=44.5820433436532, Blast_Score=275, Evalue=7e-75,
Organism=Saccharomyces cerevisiae, GI6320560, Length=321, Percent_Identity=44.8598130841121, Blast_Score=274, Evalue=2e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34701; Mature: 34570

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARHTKVLIIGSGPAGYTAAIYAARAMLKPVLIAGMEQGGQLMITTDVENYPGFADPIQ
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCC
GPWLMDQMLKQATHVGAEIVSDLVTEVETNVRPFVVRTDSGQVWTADTLIIATGAKAKWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECEEEEEECCCEEEE
GIESEQHFQGFGVSACATCDGFFYRNKDVIVVGGGNSAVEEALYLAHIAKSVTVVHRRDS
ECCCHHHHCCCCCHHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEECCCC
FRSEKILQERLFAKENVKILWNTEIAEITGAPAKPPMPPSVSGVRLRDTKTGAISDTPID
HHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCC
GVFVAIGHAPAVELFKGKVKLKDNGYMWTAPDSTATDVEGIFAAGDVTDDIYRQAITAAG
EEEEEECCCCEEEEEECEEEEECCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
MGCMAALEAERYLTAQQPLAVAAE
CHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure 
SARHTKVLIIGSGPAGYTAAIYAARAMLKPVLIAGMEQGGQLMITTDVENYPGFADPIQ
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCC
GPWLMDQMLKQATHVGAEIVSDLVTEVETNVRPFVVRTDSGQVWTADTLIIATGAKAKWL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECEEEEEECCCEEEE
GIESEQHFQGFGVSACATCDGFFYRNKDVIVVGGGNSAVEEALYLAHIAKSVTVVHRRDS
ECCCHHHHCCCCCHHHEECCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHEEEECCCC
FRSEKILQERLFAKENVKILWNTEIAEITGAPAKPPMPPSVSGVRLRDTKTGAISDTPID
HHHHHHHHHHHHCCCCCEEEEECCHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCC
GVFVAIGHAPAVELFKGKVKLKDNGYMWTAPDSTATDVEGIFAAGDVTDDIYRQAITAAG
EEEEEECCCCEEEEEECEEEEECCCEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCC
MGCMAALEAERYLTAQQPLAVAAE
CHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]