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The map label for this gene is sdaA [H]

Identifier: 159184902

GI number: 159184902

Start: 1743749

End: 1745152

Strand: Reverse

Name: sdaA [H]

Synonym: Atu1759

Alternate gene names: 159184902

Gene position: 1745152-1743749 (Counterclockwise)

Preceding gene: 15889064

Following gene: 15889061

Centisome position: 61.41

GC content: 61.32

Gene sequence:

>1404_bases
ATGTTTCTTTCGGTCTTCGACGTCTTCAAGATCGGTATCGGTCCTTCCAGCTCCCATACGATGGGGCCGATGACGGCTGC
AAACCGCTTTCTGGCGCTGATCCTCAGTGACGAGTGGCCGCGGCCGGCGGGTGCGGCCGTGGCGCAGCTGAAAGTCAGCC
TGCACGGATCTCTCGCCTTTACGGGCATCGGCCATGGCACCGGGCGTGCCGTCGTTCTCGGTCTCACCGGCGAGCGGCCT
GATCTTGTCGATCCCGATGCGATGGACGCCATCATCGAGACCGTGGAAAAGGCAGGCACGGTCACGCCGCCCGGCCACCC
GTCCTATGTGTTCCGCCCGGCCGAAGATCTGGTTTTTGACAAGAAGAACCCGCTGCCCGGCCATGCCAACGGCATGATCT
TTTCCGCCTTCGACAATCAGGGCAGGCTGCTCATCAAGCGCATCTATTATTCCGTCGGCGGCGGTTTCGTCGTGACCGAT
ACGGAACTGGAGGCGATCAAGCAGCGCGGAAAGACCATCGATAATGGTCCGCGCGTGCCTTATCCCTTTGCGTCCGCGCG
GGAAATGCTCGATATGGCTACCCGTTCCGGCCGCACCATCGCCCAGATGAAGCGTGCCAACGAGGAAACGGTCGTCTCAC
GCGACGAGCTGAACGAGCGGCTCGATCAAATCTGGGAGGCAATGAACGGTTGCATCGAACGTGGTCTGAAGGTGGATGGT
ATCATGCCCGGAGGCCTCAAGGTGCGCCGCCGTGCCCGTTCCATCTATGAGAAACTCAATGAGGAGTGGCGCAGCAACCG
GCTCAACCCCGTCATGGCGAATGACTGGCTCAGTGTTTACGCCATGGCCGTGAACGAAGAGAACGCCGCCGGCGGGCGTG
TCGTCACGGCGCCGACCAATGGTGCGGCGGGCGTCGTGCCTGCCACTGTCAGATATTTCCGGCATTTTCACGAGGATGCG
ACTGTCGACGACGTGCGTGACTTCCTGCTGACGGCGGCGGCCATCGGCGGCATCATCAAGCATAATGCTTCCATTTCGGG
CGCAGAGGTGGGCTGTCAGGGCGAGGTGGGTTCGGCTGCTGCAATGGCAGCGGCGGGGCTTGCTGCCGTCATGGGCGGAT
CACCTGAACAGATCGAAAATGCTGCCGAAATCGCGCTTGAACATCACCTTGGCATGACCTGCGATCCGATTGCGGGACTG
GTGCAGGTGCCCTGCATCGAGCGCAACGCACTGGGTGCCGTCAAGGCAGTGACGGCGGCCTCGCTGGCATTGAAGGGCGA
CGGGCAACATTTCGTGCCGCTCGATGCCTGTATCGAGACCATGCGCCAGACCGGCAATGACATGAGTGAAAAATACAAGG
AAACCTCCACCGGCGGCCTCGCCGTCAACGTTGTGGAGTGCTGA

Upstream 100 bases:

>100_bases
CCTTCATGTCGCAGCTGCAAAAGCCGGTGCCGCTCTTTTGTGGCGATCCGCTGCAGCTTTGGATATGATGGGTAGAAATC
CAATATGCAGGGTATATTTC

Downstream 100 bases:

>100_bases
GCGGGCAGGGCGTGAGGCACCGTCCAGATGCTTGACGCCCGTCGCAAAAAGGCATTGATAGGGGCATGCCTCTACATCTC
ATTAAACTTTGCGTCGGTGC

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MFLSVFDVFKIGIGPSSSHTMGPMTAANRFLALILSDEWPRPAGAAVAQLKVSLHGSLAFTGIGHGTGRAVVLGLTGERP
DLVDPDAMDAIIETVEKAGTVTPPGHPSYVFRPAEDLVFDKKNPLPGHANGMIFSAFDNQGRLLIKRIYYSVGGGFVVTD
TELEAIKQRGKTIDNGPRVPYPFASAREMLDMATRSGRTIAQMKRANEETVVSRDELNERLDQIWEAMNGCIERGLKVDG
IMPGGLKVRRRARSIYEKLNEEWRSNRLNPVMANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVVPATVRYFRHFHEDA
TVDDVRDFLLTAAAIGGIIKHNASISGAEVGCQGEVGSAAAMAAAGLAAVMGGSPEQIENAAEIALEHHLGMTCDPIAGL
VQVPCIERNALGAVKAVTAASLALKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC

Sequences:

>Translated_467_residues
MFLSVFDVFKIGIGPSSSHTMGPMTAANRFLALILSDEWPRPAGAAVAQLKVSLHGSLAFTGIGHGTGRAVVLGLTGERP
DLVDPDAMDAIIETVEKAGTVTPPGHPSYVFRPAEDLVFDKKNPLPGHANGMIFSAFDNQGRLLIKRIYYSVGGGFVVTD
TELEAIKQRGKTIDNGPRVPYPFASAREMLDMATRSGRTIAQMKRANEETVVSRDELNERLDQIWEAMNGCIERGLKVDG
IMPGGLKVRRRARSIYEKLNEEWRSNRLNPVMANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVVPATVRYFRHFHEDA
TVDDVRDFLLTAAAIGGIIKHNASISGAEVGCQGEVGSAAAMAAAGLAAVMGGSPEQIENAAEIALEHHLGMTCDPIAGL
VQVPCIERNALGAVKAVTAASLALKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC
>Mature_467_residues
MFLSVFDVFKIGIGPSSSHTMGPMTAANRFLALILSDEWPRPAGAAVAQLKVSLHGSLAFTGIGHGTGRAVVLGLTGERP
DLVDPDAMDAIIETVEKAGTVTPPGHPSYVFRPAEDLVFDKKNPLPGHANGMIFSAFDNQGRLLIKRIYYSVGGGFVVTD
TELEAIKQRGKTIDNGPRVPYPFASAREMLDMATRSGRTIAQMKRANEETVVSRDELNERLDQIWEAMNGCIERGLKVDG
IMPGGLKVRRRARSIYEKLNEEWRSNRLNPVMANDWLSVYAMAVNEENAAGGRVVTAPTNGAAGVVPATVRYFRHFHEDA
TVDDVRDFLLTAAAIGGIIKHNASISGAEVGCQGEVGSAAAMAAAGLAAVMGGSPEQIENAAEIALEHHLGMTCDPIAGL
VQVPCIERNALGAVKAVTAASLALKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=467, Percent_Identity=46.0385438972163, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1788116, Length=465, Percent_Identity=46.2365591397849, Blast_Score=403, Evalue=1e-113,
Organism=Escherichia coli, GI48994925, Length=467, Percent_Identity=46.8950749464668, Blast_Score=398, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49781; Mature: 49781

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSVFDVFKIGIGPSSSHTMGPMTAANRFLALILSDEWPRPAGAAVAQLKVSLHGSLAF
CEEEHEEHHHHCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCCHHHHHEEEEECCCEEE
TGIGHGTGRAVVLGLTGERPDLVDPDAMDAIIETVEKAGTVTPPGHPSYVFRPAEDLVFD
EECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHCC
KKNPLPGHANGMIFSAFDNQGRLLIKRIYYSVGGGFVVTDTELEAIKQRGKTIDNGPRVP
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCCCCCC
YPFASAREMLDMATRSGRTIAQMKRANEETVVSRDELNERLDQIWEAMNGCIERGLKVDG
CCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
IMPGGLKVRRRARSIYEKLNEEWRSNRLNPVMANDWLSVYAMAVNEENAAGGRVVTAPTN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCHHEEEEEEECCCCCCCCEEEECCCC
GAAGVVPATVRYFRHFHEDATVDDVRDFLLTAAAIGGIIKHNASISGAEVGCQGEVGSAA
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AMAAAGLAAVMGGSPEQIENAAEIALEHHLGMTCDPIAGLVQVPCIERNALGAVKAVTAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
SLALKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC
HEEEECCCCEECCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MFLSVFDVFKIGIGPSSSHTMGPMTAANRFLALILSDEWPRPAGAAVAQLKVSLHGSLAF
CEEEHEEHHHHCCCCCCCCCCCCHHHHHHEEEEEECCCCCCCCCHHHHHEEEEECCCEEE
TGIGHGTGRAVVLGLTGERPDLVDPDAMDAIIETVEKAGTVTPPGHPSYVFRPAEDLVFD
EECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECHHHHHCC
KKNPLPGHANGMIFSAFDNQGRLLIKRIYYSVGGGFVVTDTELEAIKQRGKTIDNGPRVP
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCCCCCC
YPFASAREMLDMATRSGRTIAQMKRANEETVVSRDELNERLDQIWEAMNGCIERGLKVDG
CCHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
IMPGGLKVRRRARSIYEKLNEEWRSNRLNPVMANDWLSVYAMAVNEENAAGGRVVTAPTN
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCHHEEEEEEECCCCCCCCEEEECCCC
GAAGVVPATVRYFRHFHEDATVDDVRDFLLTAAAIGGIIKHNASISGAEVGCQGEVGSAA
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
AMAAAGLAAVMGGSPEQIENAAEIALEHHLGMTCDPIAGLVQVPCIERNALGAVKAVTAA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
SLALKGDGQHFVPLDACIETMRQTGNDMSEKYKETSTGGLAVNVVEC
HEEEECCCCEECCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]