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The map label for this gene is rpiA

Identifier: 159184838

GI number: 159184838

Start: 1595739

End: 1596419

Strand: Reverse

Name: rpiA

Synonym: Atu1613

Alternate gene names: 159184838

Gene position: 1596419-1595739 (Counterclockwise)

Preceding gene: 15888928

Following gene: 15888925

Centisome position: 56.18

GC content: 61.23

Gene sequence:

>681_bases
ATGAAGATCAAGGCCGCCGAGGCCGCATTGTCCCATGTGCAGGACGGCATGCGGCTGGGTATCGGCACCGGTTCGACGGC
CGAGGAATTCGTCCGTCTTCTGGCGGAGAAGGTTGCGGCCGGCCTGAAGGTCGAGGGCGTTCCCACATCCGAGCGTACCG
CACGTCTGTGCGTCGAGCTTGGCGTGCCGCTGAAATCCCTCGATGAATTGCCGGAACTGGATCTGACCATCGACGGCGCC
GACGAAGTTGATCATGTACTACGTCTCGTCAAGGGCGGCGGCGGCGCGCTGCTGCGCGAAAAGATCGTGGCGGCAGCATC
CGGCCGCATGATCGTCATCGCCGACCAGAGCAAGGTCGTCGAGACGCTGGGCGCCTTTCCGCTTCCCATCGAGATCAATC
CCTTCGGCCAGGTGGCGACACGCATCGCCATTGAAAAACTGGCGGCTCGGTCGGGTCTTTCGGGCGAACTGACGATGCGT
TCTTCCGGCGACGGCGCCTTCATGACGGATGGCGGACACCTGATCCTCGACGCATCTTTTGGCCGTATTCCTGATGCAGA
AGCACTGGCACGCGAGCTGAACACTATCCCCGGTGTTGTTGAGCACGGACTTTTCATAAATTTGGCATCGCTTGCCATCA
TCGCGGGCCCTGAAGGCGCCCGCATGATGCAGGCAGTATAA

Upstream 100 bases:

>100_bases
TTTGTTGCCTTGAAAAAGGCTTTCGTTTGGCTTTCGACCCGTGTAAACAGCACGGCGACGACAAAGCTACCGGAGTTTCA
GGCACATGGATGCCCGCCAG

Downstream 100 bases:

>100_bases
CAGGAGCGAGATTTTCATGATCAAACTAGCGGGACTGGGCAAAGCTGCCGCTGCTTCGATCCTCATTTCCGGCATCGTGT
TCGGTACTGCCGCACGCGCG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKIKAAEAALSHVQDGMRLGIGTGSTAEEFVRLLAEKVAAGLKVEGVPTSERTARLCVELGVPLKSLDELPELDLTIDGA
DEVDHVLRLVKGGGGALLREKIVAAASGRMIVIADQSKVVETLGAFPLPIEINPFGQVATRIAIEKLAARSGLSGELTMR
SSGDGAFMTDGGHLILDASFGRIPDAEALARELNTIPGVVEHGLFINLASLAIIAGPEGARMMQAV

Sequences:

>Translated_226_residues
MKIKAAEAALSHVQDGMRLGIGTGSTAEEFVRLLAEKVAAGLKVEGVPTSERTARLCVELGVPLKSLDELPELDLTIDGA
DEVDHVLRLVKGGGGALLREKIVAAASGRMIVIADQSKVVETLGAFPLPIEINPFGQVATRIAIEKLAARSGLSGELTMR
SSGDGAFMTDGGHLILDASFGRIPDAEALARELNTIPGVVEHGLFINLASLAIIAGPEGARMMQAV
>Mature_226_residues
MKIKAAEAALSHVQDGMRLGIGTGSTAEEFVRLLAEKVAAGLKVEGVPTSERTARLCVELGVPLKSLDELPELDLTIDGA
DEVDHVLRLVKGGGGALLREKIVAAASGRMIVIADQSKVVETLGAFPLPIEINPFGQVATRIAIEKLAARSGLSGELTMR
SSGDGAFMTDGGHLILDASFGRIPDAEALARELNTIPGVVEHGLFINLASLAIIAGPEGARMMQAV

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=227, Percent_Identity=39.647577092511, Blast_Score=141, Evalue=4e-34,
Organism=Escherichia coli, GI1789280, Length=225, Percent_Identity=37.7777777777778, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17551758, Length=218, Percent_Identity=39.4495412844037, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324669, Length=226, Percent_Identity=34.9557522123894, Blast_Score=111, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281364072, Length=223, Percent_Identity=37.219730941704, Blast_Score=125, Evalue=3e-29,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_AGRT5 (Q8UEZ0)

Other databases:

- EMBL:   AE007869
- PIR:   AI2774
- PIR:   G97554
- RefSeq:   NP_354607.2
- ProteinModelPortal:   Q8UEZ0
- SMR:   Q8UEZ0
- STRING:   Q8UEZ0
- GeneID:   1133651
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1613
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- PhylomeDB:   Q8UEZ0
- ProtClustDB:   PRK00702
- BioCyc:   ATUM176299-1:ATU1613-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 23539; Mature: 23539

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKAAEAALSHVQDGMRLGIGTGSTAEEFVRLLAEKVAAGLKVEGVPTSERTARLCVEL
CCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHH
GVPLKSLDELPELDLTIDGADEVDHVLRLVKGGGGALLREKIVAAASGRMIVIADQSKVV
CCCHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCHHHH
ETLGAFPLPIEINPFGQVATRIAIEKLAARSGLSGELTMRSSGDGAFMTDGGHLILDASF
HHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCEEEEECCC
GRIPDAEALARELNTIPGVVEHGLFINLASLAIIAGPEGARMMQAV
CCCCCHHHHHHHHHHCCHHHHCCHHEEEEHEEEEECCCCCHHHHCC
>Mature Secondary Structure
MKIKAAEAALSHVQDGMRLGIGTGSTAEEFVRLLAEKVAAGLKVEGVPTSERTARLCVEL
CCCCHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHH
GVPLKSLDELPELDLTIDGADEVDHVLRLVKGGGGALLREKIVAAASGRMIVIADQSKVV
CCCHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCHHHH
ETLGAFPLPIEINPFGQVATRIAIEKLAARSGLSGELTMRSSGDGAFMTDGGHLILDASF
HHHCCCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCCEEEEECCC
GRIPDAEALARELNTIPGVVEHGLFINLASLAIIAGPEGARMMQAV
CCCCCHHHHHHHHHHCCHHHHCCHHEEEEHEEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194