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The map label for this gene is aatC [H]

Identifier: 159184829

GI number: 159184829

Start: 1571703

End: 1572923

Strand: Reverse

Name: aatC [H]

Synonym: Atu1589

Alternate gene names: 159184829

Gene position: 1572923-1571703 (Counterclockwise)

Preceding gene: 159184830

Following gene: 159184828

Centisome position: 55.35

GC content: 59.79

Gene sequence:

>1221_bases
ATGGAAGAGTTTCATAAGGTCCGGCGTCTGCCGCAATACGTCTTCGAACAGGTCAACCGTTTGAAAGCGAGCGCGCGAGC
GGCCGGGGCCGATATCATCGATCTCGGCATGGGTAATCCCGACCTTCCGACCCCCAAGGCCATCGTCGACAAGCTCTGCG
AAGTCGTTCAGGACCCGCGCACCCATCGTTATTCCTCGTCCAAGGGCATTCCCGGCCTTCGCCGCGCACAGGCCGGCTAT
TATGCCCGCCGTTTCGGCGTGAAGCTGAACCCCGATACGCAGGTCGTCGCCACGCTTGGCTCCAAGGAAGGTTTCGCCAA
TATGGCGCAGGCCATCACGGCACCAGGTGACGTGATCCTGTGCCCGAACCCGACCTATCCGATCCATGCCTTCGGCTTCC
TGATGGCGGGCGGCGTTATCCGTTCGATGAATGTGGAGCCGGATGAGAGCTTCTTCGGGCCTTTAGAGCGGGCGGTGCGT
CACTCTATTCCAAAGCCGCTGGCGCTAATCGTCAACTATCCGTCGAACCCGACGGCGCATGTCGCATCGCTCGATTTCTA
CAAGGATGTGATCGCGTTTGCGAAGAAGCACGAAATCATAGTGCTCTCCGATCTTGCCTATTCGGAAATCTACTTCGACG
ACAACAATCCGCCGCCTTCGGTTCTCGAAGTTCCCGGCGCGATCGACGTTGCGGTGGAGTTCACCTCCATGTCGAAGACC
TTCTCCATGCCCGGCTGGCGCATGGGCTTCGCTGTCGGGAACGAGCGGCTGATCGCGGCGCTGACCCGCGTGAAGTCCTA
CCTCGATTACGGCGCCTTCACGCCGATCCAGGTGGCGGCGACGCATGCGCTGAACGGTGACGGTTCCGACATCGCCGAAG
TGCGCAGCGTCTATCGCCGCCGCCGCGATGTCATGGTCGATACGTTCGGCAAGGCCGGCTTCGAGGTTCCGCCGCCGGCA
GCGACGATGTTCGCCTGGGCGAAGATCCCGGAAAAATTCCGCCATCTCGGCAGCCTGGAGTTTTCCAAGCTTCTGGTCGA
GAAGGCAGATATCGCCGTTGCTCCCGGCATCGGCTTTGGCGAAATGGGCGATGATTACGTCCGTCTTGCGCTTGTGGAAA
ACGAGCATCGAATTCGTCAGGCAGCGCGCAATCTGAAGCGTTTCCTGTCGAGTGCTGACGAAACGATGCACAATGTCGTT
TCGCTCAACGCCCACAGATAA

Upstream 100 bases:

>100_bases
ATAACGCCTGCCGGGTCGGTTCGTGTCGGCGGCGTTTAAAAACAAAAAACGAACCTTCGTTATGGGCCGGCAGAACCGGT
CCATTCCCATGAGGAAAGTG

Downstream 100 bases:

>100_bases
GGGCAACCGAAGGCGGCCGGGCCTCGGCCGCCACCATCACCAGCAAATCAGGAACATACCCATGGCAGATTCATTGAGAA
TCGGCATAGCGGGGCTCGGC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MEEFHKVRRLPQYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPKAIVDKLCEVVQDPRTHRYSSSKGIPGLRRAQAGY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFLMAGGVIRSMNVEPDESFFGPLERAVR
HSIPKPLALIVNYPSNPTAHVASLDFYKDVIAFAKKHEIIVLSDLAYSEIYFDDNNPPPSVLEVPGAIDVAVEFTSMSKT
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRSVYRRRRDVMVDTFGKAGFEVPPPA
ATMFAWAKIPEKFRHLGSLEFSKLLVEKADIAVAPGIGFGEMGDDYVRLALVENEHRIRQAARNLKRFLSSADETMHNVV
SLNAHR

Sequences:

>Translated_406_residues
MEEFHKVRRLPQYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPKAIVDKLCEVVQDPRTHRYSSSKGIPGLRRAQAGY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFLMAGGVIRSMNVEPDESFFGPLERAVR
HSIPKPLALIVNYPSNPTAHVASLDFYKDVIAFAKKHEIIVLSDLAYSEIYFDDNNPPPSVLEVPGAIDVAVEFTSMSKT
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRSVYRRRRDVMVDTFGKAGFEVPPPA
ATMFAWAKIPEKFRHLGSLEFSKLLVEKADIAVAPGIGFGEMGDDYVRLALVENEHRIRQAARNLKRFLSSADETMHNVV
SLNAHR
>Mature_406_residues
MEEFHKVRRLPQYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPKAIVDKLCEVVQDPRTHRYSSSKGIPGLRRAQAGY
YARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVILCPNPTYPIHAFGFLMAGGVIRSMNVEPDESFFGPLERAVR
HSIPKPLALIVNYPSNPTAHVASLDFYKDVIAFAKKHEIIVLSDLAYSEIYFDDNNPPPSVLEVPGAIDVAVEFTSMSKT
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRSVYRRRRDVMVDTFGKAGFEVPPPA
ATMFAWAKIPEKFRHLGSLEFSKLLVEKADIAVAPGIGFGEMGDDYVRLALVENEHRIRQAARNLKRFLSSADETMHNVV
SLNAHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=396, Percent_Identity=21.969696969697, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI169881279, Length=396, Percent_Identity=21.969696969697, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI56713254, Length=271, Percent_Identity=24.7232472324723, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI56713256, Length=271, Percent_Identity=24.7232472324723, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4507369, Length=230, Percent_Identity=24.7826086956522, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=50.6527415143603, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1786816, Length=385, Percent_Identity=26.4935064935065, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788627, Length=393, Percent_Identity=24.4274809160305, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=410, Percent_Identity=22.6829268292683, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71994472, Length=402, Percent_Identity=25.3731343283582, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=402, Percent_Identity=25.3731343283582, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=21.7277486910995, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=395, Percent_Identity=21.7721518987342, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI28573069, Length=390, Percent_Identity=23.5897435897436, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24646114, Length=390, Percent_Identity=23.5897435897436, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28573067, Length=390, Percent_Identity=23.5897435897436, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI28573065, Length=390, Percent_Identity=23.5897435897436, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44733; Mature: 44733

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFHKVRRLPQYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPKAIVDKLCEVVQDPR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
THRYSSSKGIPGLRRAQAGYYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVIL
CCCCCCCCCCCCHHHHHHCHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPTYPIHAFGFLMAGGVIRSMNVEPDESFFGPLERAVRHSIPKPLALIVNYPSNPTAH
CCCCCCCHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCH
VASLDFYKDVIAFAKKHEIIVLSDLAYSEIYFDDNNPPPSVLEVPGAIDVAVEFTSMSKT
HHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCEECCCCEEEEEEEEHHHHH
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRSVYRR
HCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
RRDVMVDTFGKAGFEVPPPAATMFAWAKIPEKFRHLGSLEFSKLLVEKADIAVAPGIGFG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCC
EMGDDYVRLALVENEHRIRQAARNLKRFLSSADETMHNVVSLNAHR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEEFHKVRRLPQYVFEQVNRLKASARAAGADIIDLGMGNPDLPTPKAIVDKLCEVVQDPR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
THRYSSSKGIPGLRRAQAGYYARRFGVKLNPDTQVVATLGSKEGFANMAQAITAPGDVIL
CCCCCCCCCCCCHHHHHHCHHHHHCCCEECCCCEEEEECCCCCHHHHHHHHHCCCCCEEE
CPNPTYPIHAFGFLMAGGVIRSMNVEPDESFFGPLERAVRHSIPKPLALIVNYPSNPTAH
CCCCCCCHHHHHHHHHCCHHEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCH
VASLDFYKDVIAFAKKHEIIVLSDLAYSEIYFDDNNPPPSVLEVPGAIDVAVEFTSMSKT
HHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCCCCEECCCCEEEEEEEEHHHHH
FSMPGWRMGFAVGNERLIAALTRVKSYLDYGAFTPIQVAATHALNGDGSDIAEVRSVYRR
HCCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHH
RRDVMVDTFGKAGFEVPPPAATMFAWAKIPEKFRHLGSLEFSKLLVEKADIAVAPGIGFG
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCCCC
EMGDDYVRLALVENEHRIRQAARNLKRFLSSADETMHNVVSLNAHR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]