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The map label for this gene is tas [H]

Identifier: 159184612

GI number: 159184612

Start: 1082770

End: 1083813

Strand: Reverse

Name: tas [H]

Synonym: Atu1093

Alternate gene names: 159184612

Gene position: 1083813-1082770 (Counterclockwise)

Preceding gene: 15888442

Following gene: 159184610

Centisome position: 38.14

GC content: 61.88

Gene sequence:

>1044_bases
ATGAAACAGAAACTATTGGGTCGCACGGGCATCTCCGTGTCTGAAATCTGCCTCGGCACCATGACGTGGGGCACGCAGAA
CACTGAAGCCGAAGCGCATGCGCAGATGGATTACGCCATCGAAAACGGCGTCAATTTCTTCGATACGGCCGAGCTTTATC
CCACCACCCCCGTTTCCGCCGAAACGCAGGGACGAACGGAAGACTATATCGGTGCGTGGTTCGAAAAGACCGGCAAGCGT
GACCAGGTCGTGCTCGCCACCAAGGTCGCCGGCTCGGGCCGTGACTATATTCGCGGCGGTCGCGACATCGATGCCGCCTC
GATCCGCGAGGCGGTGGATACCAGCCTCACGAGGCTGAAGACCGATTACATCGACCTCTACCAGATTCACTGGCCTAACC
GCGGCACCTACCATTTCCGCGGCGCCTGGGGTTTCGATGCTTCCGGGCAGGACACCAAGCGCACGCTTGCCGAAATCACC
GAAAAGCTCGAGACGCTCGGCGAACTGGTGAAGGCGGGCAAGATTCGCGCCATCGGCCTTTCCAACGAAAGCGCCTGGGG
CACACAGAAATATATCGATATCGCCGAGGCCAACGGCCTGCCGCGCGTCGCCACCATCCAGAACGAATATAACCTGCTCT
ATCGCAGCTTCGACCTCGACATGGCGGAAGTCGCCCATCACGAGGATGTCGGCCTGCTCGCCTATTCGCCGCTCGCGGCG
GGGCTGCTGACAGGCAAATACCAGAACGGCGCCCGCCCGGCGGGCTCGCGCGGCACCATCAACAAGGATCTCGGCGGCCG
CCTGCAGCCGCATCAGGAAGCGCCGGTCAAGGCGTATCTGGACCTTGCCGCCGCACACGGGGTAGACCCGGCCCAGCTCG
CCATCGCCTTCTGCCTCACCCGCCCGTTCATGGCCTCTGCCATCATCGGCGCGACCACCATGGAACAGTTGAAGGTGGAT
ATTGCGGCGGTGGATGTGGCCCTGTCGGAAGACCTGCTGAAGGGTATTGCGGCGATCCACCGGCAATATCCGATGCCGAT
CTGA

Upstream 100 bases:

>100_bases
GTTTTCCCCTTTCTTTTAGTCATATTTTTTCTTGCACTGCGGCAATTCCCGATTAGTTTCACACCACCTTCCAAAACTGG
CCAAGCACCGGGATACCTCC

Downstream 100 bases:

>100_bases
CACGATTACAGCGCGCTTTTTCGCCCTTTGCCCTTGCATTCCGGGCAAATTTGCGTATAAGCGCGCTGTTCACAACACCC
GGTCCAATTGGCTGGTGGCT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKQKLLGRTGISVSEICLGTMTWGTQNTEAEAHAQMDYAIENGVNFFDTAELYPTTPVSAETQGRTEDYIGAWFEKTGKR
DQVVLATKVAGSGRDYIRGGRDIDAASIREAVDTSLTRLKTDYIDLYQIHWPNRGTYHFRGAWGFDASGQDTKRTLAEIT
EKLETLGELVKAGKIRAIGLSNESAWGTQKYIDIAEANGLPRVATIQNEYNLLYRSFDLDMAEVAHHEDVGLLAYSPLAA
GLLTGKYQNGARPAGSRGTINKDLGGRLQPHQEAPVKAYLDLAAAHGVDPAQLAIAFCLTRPFMASAIIGATTMEQLKVD
IAAVDVALSEDLLKGIAAIHRQYPMPI

Sequences:

>Translated_347_residues
MKQKLLGRTGISVSEICLGTMTWGTQNTEAEAHAQMDYAIENGVNFFDTAELYPTTPVSAETQGRTEDYIGAWFEKTGKR
DQVVLATKVAGSGRDYIRGGRDIDAASIREAVDTSLTRLKTDYIDLYQIHWPNRGTYHFRGAWGFDASGQDTKRTLAEIT
EKLETLGELVKAGKIRAIGLSNESAWGTQKYIDIAEANGLPRVATIQNEYNLLYRSFDLDMAEVAHHEDVGLLAYSPLAA
GLLTGKYQNGARPAGSRGTINKDLGGRLQPHQEAPVKAYLDLAAAHGVDPAQLAIAFCLTRPFMASAIIGATTMEQLKVD
IAAVDVALSEDLLKGIAAIHRQYPMPI
>Mature_347_residues
MKQKLLGRTGISVSEICLGTMTWGTQNTEAEAHAQMDYAIENGVNFFDTAELYPTTPVSAETQGRTEDYIGAWFEKTGKR
DQVVLATKVAGSGRDYIRGGRDIDAASIREAVDTSLTRLKTDYIDLYQIHWPNRGTYHFRGAWGFDASGQDTKRTLAEIT
EKLETLGELVKAGKIRAIGLSNESAWGTQKYIDIAEANGLPRVATIQNEYNLLYRSFDLDMAEVAHHEDVGLLAYSPLAA
GLLTGKYQNGARPAGSRGTINKDLGGRLQPHQEAPVKAYLDLAAAHGVDPAQLAIAFCLTRPFMASAIIGATTMEQLKVD
IAAVDVALSEDLLKGIAAIHRQYPMPI

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=358, Percent_Identity=29.0502793296089, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI27436966, Length=366, Percent_Identity=28.9617486338798, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI27436962, Length=356, Percent_Identity=28.6516853932584, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI4504825, Length=353, Percent_Identity=28.6118980169972, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI27436969, Length=353, Percent_Identity=28.6118980169972, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI223718702, Length=242, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI41327764, Length=242, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI41152114, Length=160, Percent_Identity=28.75, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=47.2779369627507, Blast_Score=323, Evalue=8e-90,
Organism=Escherichia coli, GI87081735, Length=354, Percent_Identity=29.3785310734463, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788070, Length=351, Percent_Identity=28.4900284900285, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789375, Length=343, Percent_Identity=27.9883381924198, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788081, Length=351, Percent_Identity=26.7806267806268, Blast_Score=85, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6323998, Length=353, Percent_Identity=26.9121813031161, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=324, Percent_Identity=25.6172839506173, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=352, Percent_Identity=24.7159090909091, Blast_Score=93, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=358, Percent_Identity=25.4189944134078, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=268, Percent_Identity=25.3731343283582, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=26.7267267267267, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 37835; Mature: 37835

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKLLGRTGISVSEICLGTMTWGTQNTEAEAHAQMDYAIENGVNFFDTAELYPTTPVSA
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
ETQGRTEDYIGAWFEKTGKRDQVVLATKVAGSGRDYIRGGRDIDAASIREAVDTSLTRLK
CCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
TDYIDLYQIHWPNRGTYHFRGAWGFDASGQDTKRTLAEITEKLETLGELVKAGKIRAIGL
HCCEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
SNESAWGTQKYIDIAEANGLPRVATIQNEYNLLYRSFDLDMAEVAHHEDVGLLAYSPLAA
CCCCCCCHHHHEEEHHCCCCCCEEEECCCHHEEEEECCCCHHHHHCCCCCCEEEECHHHH
GLLTGKYQNGARPAGSRGTINKDLGGRLQPHQEAPVKAYLDLAAAHGVDPAQLAIAFCLT
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
RPFMASAIIGATTMEQLKVDIAAVDVALSEDLLKGIAAIHRQYPMPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKQKLLGRTGISVSEICLGTMTWGTQNTEAEAHAQMDYAIENGVNFFDTAELYPTTPVSA
CCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCCCCCCC
ETQGRTEDYIGAWFEKTGKRDQVVLATKVAGSGRDYIRGGRDIDAASIREAVDTSLTRLK
CCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHHH
TDYIDLYQIHWPNRGTYHFRGAWGFDASGQDTKRTLAEITEKLETLGELVKAGKIRAIGL
HCCEEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
SNESAWGTQKYIDIAEANGLPRVATIQNEYNLLYRSFDLDMAEVAHHEDVGLLAYSPLAA
CCCCCCCHHHHEEEHHCCCCCCEEEECCCHHEEEEECCCCHHHHHCCCCCCEEEECHHHH
GLLTGKYQNGARPAGSRGTINKDLGGRLQPHQEAPVKAYLDLAAAHGVDPAQLAIAFCLT
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
RPFMASAIIGATTMEQLKVDIAAVDVALSEDLLKGIAAIHRQYPMPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]