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The map label for this gene is hisC [H]

Identifier: 159184577

GI number: 159184577

Start: 1006260

End: 1007372

Strand: Reverse

Name: hisC [H]

Synonym: Atu1011

Alternate gene names: 159184577

Gene position: 1007372-1006260 (Counterclockwise)

Preceding gene: 15888356

Following gene: 159184576

Centisome position: 35.45

GC content: 61.64

Gene sequence:

>1113_bases
ATGTCCGCTTTCTCACGCCTCACGCCGCTTGCCGTCTCGCTTCCCTCAACCGTTCCTTTCGTTGGCCCTGAGGCCATCGA
GCGCAGCCGCGGCCTGAAGGTGGAAGCGCGCATCGGCGCCAATGAAAGCGGCTTCGGCCCCGCGCCTTCAGTGCTTCTCG
CCATGCGGGACGCGGCGGCGGAGACCTGGATGTACAGCGATCCGGAAAATTTCGAGCTGAAGGAAGCGCTTGCCATTCAC
CACGGCGTTGCACGCGGCAATATCGCCATCGGCAGCGGGGTTGATGGATTGCTGGGGGAGATCGCCAGGCTGATCGTTGA
GCCGGGCACGCCTGTCGTCACCTCGTTTGGCGGCTATCCCACTTTCAATTACCATGTGAACGGTTTTGGCGGCAAACTCG
TCACCACGCCCTATGTCGATGATCACGAAAATCTTGACGGGCTTCTCGATCTCGTCATCCGGGAAAATGCGCCGCTCGTC
TATTTCGCCAACCCTGATAATCCGATGGGAAGCTGGTGGGAGGCGAGCGAAGTCGTCGCCTTCGCCCGCGCATTGCCGGA
AACCTGCCTGCTCATTCTGGACGAGGCCTATTGCGAAACCGGGCCCATCAGCGCCGTGCCGGCCATCGACGCGCTGATCG
GCCAACCGAATATCCTGCGCATGCGCACCTTTTCGAAAGCCTATGGGCTGGCCGGTGCGCGCGTGGGTTATGCCATCGGC
ACGCTCGGCAATGTCGAAGCCTTCGACAAGATCCGCAATCATTTCGGCATGGCGCGTATTTCCGTCGCCGGCGCCCTCGC
GGCGCTGAAGGATCAGGCCTATCTGCATGAGGTGGTTGGCAAGATTTCCGATGCCCGCGATCGTATTTCCGCGATCGCCC
GCAATAACGGCCTTTCGCCGCTGCCGTCGGCCACCAATTTCGTCACCATCGATTGCCACCGCGACGGCGCTTATGCCCGC
GCCATCGTTGATGGGCTGATGGACCATGGCGTGTTCATCCGCATGCCGGGCGTTGCCCCGCTCAACCGCTGCATTCGTGT
CAGCGCCGGCACCGCCGACAAGCTCGATCTTTTCGAGCAGGCGCTGCCAAAGGTTCTCAAGGCGATCGGGTAA

Upstream 100 bases:

>100_bases
TCCAAAACAGTCATTGGATAACCGGGCGCGCCTTGCGTCCGGTATTTTTGCACCTATTGTGAGCCGTGTTTTCAAACACA
GCTACCGGAACTTTCAGCCA

Downstream 100 bases:

>100_bases
ATTCCCAACCCAACCTCATTCCTGTGCTCGTCACAGGAATGAGGGGTGGAGAATGCCGCGGGTTCCACGCACCGATTCAA
GTTCCCCTCACAACCCCCTG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MSAFSRLTPLAVSLPSTVPFVGPEAIERSRGLKVEARIGANESGFGPAPSVLLAMRDAAAETWMYSDPENFELKEALAIH
HGVARGNIAIGSGVDGLLGEIARLIVEPGTPVVTSFGGYPTFNYHVNGFGGKLVTTPYVDDHENLDGLLDLVIRENAPLV
YFANPDNPMGSWWEASEVVAFARALPETCLLILDEAYCETGPISAVPAIDALIGQPNILRMRTFSKAYGLAGARVGYAIG
TLGNVEAFDKIRNHFGMARISVAGALAALKDQAYLHEVVGKISDARDRISAIARNNGLSPLPSATNFVTIDCHRDGAYAR
AIVDGLMDHGVFIRMPGVAPLNRCIRVSAGTADKLDLFEQALPKVLKAIG

Sequences:

>Translated_370_residues
MSAFSRLTPLAVSLPSTVPFVGPEAIERSRGLKVEARIGANESGFGPAPSVLLAMRDAAAETWMYSDPENFELKEALAIH
HGVARGNIAIGSGVDGLLGEIARLIVEPGTPVVTSFGGYPTFNYHVNGFGGKLVTTPYVDDHENLDGLLDLVIRENAPLV
YFANPDNPMGSWWEASEVVAFARALPETCLLILDEAYCETGPISAVPAIDALIGQPNILRMRTFSKAYGLAGARVGYAIG
TLGNVEAFDKIRNHFGMARISVAGALAALKDQAYLHEVVGKISDARDRISAIARNNGLSPLPSATNFVTIDCHRDGAYAR
AIVDGLMDHGVFIRMPGVAPLNRCIRVSAGTADKLDLFEQALPKVLKAIG
>Mature_369_residues
SAFSRLTPLAVSLPSTVPFVGPEAIERSRGLKVEARIGANESGFGPAPSVLLAMRDAAAETWMYSDPENFELKEALAIHH
GVARGNIAIGSGVDGLLGEIARLIVEPGTPVVTSFGGYPTFNYHVNGFGGKLVTTPYVDDHENLDGLLDLVIRENAPLVY
FANPDNPMGSWWEASEVVAFARALPETCLLILDEAYCETGPISAVPAIDALIGQPNILRMRTFSKAYGLAGARVGYAIGT
LGNVEAFDKIRNHFGMARISVAGALAALKDQAYLHEVVGKISDARDRISAIARNNGLSPLPSATNFVTIDCHRDGAYARA
IVDGLMDHGVFIRMPGVAPLNRCIRVSAGTADKLDLFEQALPKVLKAIG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=290, Percent_Identity=23.448275862069, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39410; Mature: 39278

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFSRLTPLAVSLPSTVPFVGPEAIERSRGLKVEARIGANESGFGPAPSVLLAMRDAAA
CCCHHHCCCCEEECCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
ETWMYSDPENFELKEALAIHHGVARGNIAIGSGVDGLLGEIARLIVEPGTPVVTSFGGYP
HHCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCCEEECCCCCC
TFNYHVNGFGGKLVTTPYVDDHENLDGLLDLVIRENAPLVYFANPDNPMGSWWEASEVVA
EEEEEEECCCCEEEECCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHH
FARALPETCLLILDEAYCETGPISAVPAIDALIGQPNILRMRTFSKAYGLAGARVGYAIG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHCCCCHHHHHHHC
TLGNVEAFDKIRNHFGMARISVAGALAALKDQAYLHEVVGKISDARDRISAIARNNGLSP
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LPSATNFVTIDCHRDGAYARAIVDGLMDHGVFIRMPGVAPLNRCIRVSAGTADKLDLFEQ
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHEEECCCCCHHHHHHHH
ALPKVLKAIG
HHHHHHHHCC
>Mature Secondary Structure 
SAFSRLTPLAVSLPSTVPFVGPEAIERSRGLKVEARIGANESGFGPAPSVLLAMRDAAA
CCHHHCCCCEEECCCCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
ETWMYSDPENFELKEALAIHHGVARGNIAIGSGVDGLLGEIARLIVEPGTPVVTSFGGYP
HHCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHCCCCCCEEECCCCCC
TFNYHVNGFGGKLVTTPYVDDHENLDGLLDLVIRENAPLVYFANPDNPMGSWWEASEVVA
EEEEEEECCCCEEEECCCCCCCCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHH
FARALPETCLLILDEAYCETGPISAVPAIDALIGQPNILRMRTFSKAYGLAGARVGYAIG
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHCCCCHHHHHHHC
TLGNVEAFDKIRNHFGMARISVAGALAALKDQAYLHEVVGKISDARDRISAIARNNGLSP
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LPSATNFVTIDCHRDGAYARAIVDGLMDHGVFIRMPGVAPLNRCIRVSAGTADKLDLFEQ
CCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHEEECCCCCHHHHHHHH
ALPKVLKAIG
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA