Click here to switch to the map view.

The map label for this gene is gltP [H]

Identifier: 159184471

GI number: 159184471

Start: 805152

End: 806516

Strand: Reverse

Name: gltP [H]

Synonym: Atu0804

Alternate gene names: 159184471

Gene position: 806516-805152 (Counterclockwise)

Preceding gene: 159184473

Following gene: 15888145

Centisome position: 28.38

GC content: 62.12

Gene sequence:

>1365_bases
ATGTCACAGGCAACGACGTCCGCCGGCTCCTCCGGGTCGAAACCCTTTTATCGCAATTTCGGCTTTCAGGTTCTGATTGC
CATGGTCATCGGCCTGCTGCTCGGCCTTGTTGCCCGCAACATCGGCCCCGATGCAGCCGGCAATCCGAACTGGCTTTCGG
TCACGCTGCAGACCATCGGCAGCATTTTCGTGCAGCTTTTGCGCGCGCTCGTACCGCCGCTGATCTTTACGGCTATCGTC
GCTTCCATCGCCAATCTCAAGAATCTTTCCAATGCGGCAAAGCTCGTCTGGCAGACGCTTCTGTGGTTCGCCATCACCGC
CCTGATCGCCGTGGTCATCGGCATCGTGCTCGGCCTCGTCATTCAGCCGGGCGTCAACACGGCAATTGCCAACACGGCAG
CGGCGGCCCCTTCTTCCACCGGCTCCTGGCTGGATTTCCTGAAGGGTCTCGTTCCGGCCAACGTCTTCGGCCTTGAGGCG
TCTACCAAAATCACCAACGGCGCCGGCAGCACCTCGCTGAACTTCAACGTGCTGCAGCTGCTCGTGGTTTCCATTGCTTT
TGGTGTCGCAGCCCTCAAAGCCGGCAAGGCGGCGGAACCCTTCCTCGCCTTCAACCAGTCGCTGCTCGCCATCGTGCGTA
AAATCCTGTGGTGGGTCATCCGCCTCACCCCCATCGGCACCATCGGCCTGCTCGGCCGCGCGGTTGACCAATATGGCTGG
ACGACGCTGTCGCAGCTCGGCTGGTATGCGGCGGCCGTTTATATCGGTCTCGCGCTCGTGCTCTTCGTCGTCTATCCGGC
GCTGCTTCTCGCCCATGGTCTGAAGCCTTCGCGGTTCTTTGCGGGCGCATGGCCGGCCATCCAGCTGGCCTTCGTGTCGC
GCTCCTCCATCGGCACGCTGCCCGTCACCGAAACCGTGACGGAAAAGAGCCTTGGCGTGCCGCGCGAATATGCCGCCTTC
TCCGTGCCGCTCGGCGCTACCACCAAGATGGATGGCTGCGCCGCGATCTATCCGGCAATCTCGGCGATCTTCATCGCGCA
GTTCTTCCAGGTGCCGCTCGGCATTCAGGAATATGTGCTGATCGTCTTCGTGTCCGTGCTCGGTTCCGCCGCAACGGCGG
GCCTTACAGGCGCGGTTGTGATGCTGACGTTGACGCTTTCCACGCTCGGCCTGCCGCTTGAAGGTGTCGGCCTGCTGCTC
GCAATCGATCCGATCCTCGACATGGGCCGCACGGCGGTCAACGTCGCCGGCCAGGCACTGGTGCCCACCATCGTCGCCAA
GCGCGAAGGCATTCTCAATGAGGCGGTTTATAACAACGCCAAGGATATCGACACGCTCGATGACCGTGAGGCCGTGACGG
CCTGA

Upstream 100 bases:

>100_bases
TTAATTGCTGAGGAAATCGGCGTATCCTCGGCGACCTCCCTCGAGAATGCGTGTAAAAAGTGCAACATTCTCGTTTTCTT
GCACAATAAAGAGACAGATC

Downstream 100 bases:

>100_bases
CGGAGAACTGGTCAAAAAGATACGGTGCGCTCCACTTCGAAGCGCACCGTAAATAACGTGCGCCACCCGGCTTCTCGCCA
GAATATCCACATTTTTGACA

Product: proton/glutamate transport protein

Products: NA

Alternate protein names: Glutamate-aspartate carrier protein [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSQATTSAGSSGSKPFYRNFGFQVLIAMVIGLLLGLVARNIGPDAAGNPNWLSVTLQTIGSIFVQLLRALVPPLIFTAIV
ASIANLKNLSNAAKLVWQTLLWFAITALIAVVIGIVLGLVIQPGVNTAIANTAAAAPSSTGSWLDFLKGLVPANVFGLEA
STKITNGAGSTSLNFNVLQLLVVSIAFGVAALKAGKAAEPFLAFNQSLLAIVRKILWWVIRLTPIGTIGLLGRAVDQYGW
TTLSQLGWYAAAVYIGLALVLFVVYPALLLAHGLKPSRFFAGAWPAIQLAFVSRSSIGTLPVTETVTEKSLGVPREYAAF
SVPLGATTKMDGCAAIYPAISAIFIAQFFQVPLGIQEYVLIVFVSVLGSAATAGLTGAVVMLTLTLSTLGLPLEGVGLLL
AIDPILDMGRTAVNVAGQALVPTIVAKREGILNEAVYNNAKDIDTLDDREAVTA

Sequences:

>Translated_454_residues
MSQATTSAGSSGSKPFYRNFGFQVLIAMVIGLLLGLVARNIGPDAAGNPNWLSVTLQTIGSIFVQLLRALVPPLIFTAIV
ASIANLKNLSNAAKLVWQTLLWFAITALIAVVIGIVLGLVIQPGVNTAIANTAAAAPSSTGSWLDFLKGLVPANVFGLEA
STKITNGAGSTSLNFNVLQLLVVSIAFGVAALKAGKAAEPFLAFNQSLLAIVRKILWWVIRLTPIGTIGLLGRAVDQYGW
TTLSQLGWYAAAVYIGLALVLFVVYPALLLAHGLKPSRFFAGAWPAIQLAFVSRSSIGTLPVTETVTEKSLGVPREYAAF
SVPLGATTKMDGCAAIYPAISAIFIAQFFQVPLGIQEYVLIVFVSVLGSAATAGLTGAVVMLTLTLSTLGLPLEGVGLLL
AIDPILDMGRTAVNVAGQALVPTIVAKREGILNEAVYNNAKDIDTLDDREAVTA
>Mature_453_residues
SQATTSAGSSGSKPFYRNFGFQVLIAMVIGLLLGLVARNIGPDAAGNPNWLSVTLQTIGSIFVQLLRALVPPLIFTAIVA
SIANLKNLSNAAKLVWQTLLWFAITALIAVVIGIVLGLVIQPGVNTAIANTAAAAPSSTGSWLDFLKGLVPANVFGLEAS
TKITNGAGSTSLNFNVLQLLVVSIAFGVAALKAGKAAEPFLAFNQSLLAIVRKILWWVIRLTPIGTIGLLGRAVDQYGWT
TLSQLGWYAAAVYIGLALVLFVVYPALLLAHGLKPSRFFAGAWPAIQLAFVSRSSIGTLPVTETVTEKSLGVPREYAAFS
VPLGATTKMDGCAAIYPAISAIFIAQFFQVPLGIQEYVLIVFVSVLGSAATAGLTGAVVMLTLTLSTLGLPLEGVGLLLA
IDPILDMGRTAVNVAGQALVPTIVAKREGILNEAVYNNAKDIDTLDDREAVTA

Specific function: This carrier protein is part of the Na(+)-dependent, binding-protein-independent glutamate-aspartate transport system [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI66773030, Length=412, Percent_Identity=30.5825242718447, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI40254478, Length=506, Percent_Identity=29.0513833992095, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4827012, Length=451, Percent_Identity=27.7161862527716, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI194239697, Length=473, Percent_Identity=26.4270613107822, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI5032093, Length=341, Percent_Identity=30.4985337243402, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI21314632, Length=397, Percent_Identity=27.9596977329975, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI223468566, Length=267, Percent_Identity=32.2097378277154, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=33.0708661417323, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI169790839, Length=434, Percent_Identity=28.3410138248848, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI262359914, Length=372, Percent_Identity=27.4193548387097, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI301601644, Length=123, Percent_Identity=38.2113821138211, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1788024, Length=411, Percent_Identity=31.1435523114355, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1789947, Length=446, Percent_Identity=28.0269058295964, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790514, Length=431, Percent_Identity=28.0742459396752, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789473, Length=400, Percent_Identity=26.25, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71996953, Length=469, Percent_Identity=29.8507462686567, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17537407, Length=417, Percent_Identity=29.7362110311751, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71983106, Length=437, Percent_Identity=29.9771167048055, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71983099, Length=437, Percent_Identity=29.9771167048055, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI193206505, Length=413, Percent_Identity=29.0556900726392, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17541374, Length=427, Percent_Identity=28.3372365339578, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193206654, Length=465, Percent_Identity=24.5161290322581, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24583025, Length=456, Percent_Identity=26.3157894736842, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17137668, Length=456, Percent_Identity=26.3157894736842, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24583023, Length=456, Percent_Identity=26.3157894736842, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281360481, Length=434, Percent_Identity=25.5760368663594, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360483, Length=434, Percent_Identity=25.5760368663594, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17137666, Length=434, Percent_Identity=25.5760368663594, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR018107 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 47429; Mature: 47298

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SQATTSAGSSGSKPFYRNFGFQVLIAMVIGLLLGLVARNIGPDAAGNPNWLSVTLQTIG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
SIFVQLLRALVPPLIFTAIVASIANLKNLSNAAKLVWQTLLWFAITALIAVVIGIVLGLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQPGVNTAIANTAAAAPSSTGSWLDFLKGLVPANVFGLEASTKITNGAGSTSLNFNVLQL
HCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHH
LVVSIAFGVAALKAGKAAEPFLAFNQSLLAIVRKILWWVIRLTPIGTIGLLGRAVDQYGW
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCH
TTLSQLGWYAAAVYIGLALVLFVVYPALLLAHGLKPSRFFAGAWPAIQLAFVSRSSIGTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHCCCCCCC
PVTETVTEKSLGVPREYAAFSVPLGATTKMDGCAAIYPAISAIFIAQFFQVPLGIQEYVL
CCHHHHHHHHCCCCHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
IVFVSVLGSAATAGLTGAVVMLTLTLSTLGLPLEGVGLLLAIDPILDMGRTAVNVAGQAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHCCHHH
VPTIVAKREGILNEAVYNNAKDIDTLDDREAVTA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751298; 9384377 [H]