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The map label for this gene is aroC

Identifier: 159184451

GI number: 159184451

Start: 751629

End: 752726

Strand: Reverse

Name: aroC

Synonym: Atu0754

Alternate gene names: 159184451

Gene position: 752726-751629 (Counterclockwise)

Preceding gene: 15888099

Following gene: 15888096

Centisome position: 26.49

GC content: 61.93

Gene sequence:

>1098_bases
ATGTCGCATAACAGTTTCGGTCATCTTTTTCGCGTTACTACCTGGGGTGAAAGCCACGGGCCGTCACTTGGCTGTGTGGT
GGATGGTTGCCCGCCCGGCATCCGCTTTACCCTTGCCGAGGTGCAGCACTGGATGGACAAGCGCAAGCCCGGCCAGAGCC
GCTTCGTGACCCAGCGCCGCGAGGATGACATCGTGAAGGTTCTGTCCGGCGTGATGCTGGACGAGGACGGCGAGACGATG
ACGACGACAGGCACGCCGATTTCCATGCTGATCGAAAATACCGACCAGCGCTCCAAGGATTACGGTGAGATTGCCAGGCG
TTTCCGCCCGGGCCATGCGGATTTCACCTATGACCTGAAATATGGCATTCGCGATTATCGCGGCGGCGGGCGTTCTTCTG
CGCGCGAGACGGCGGCGCGTGTCGCCGCCGGCGCAATCGCCCGCAAGGTGGTGCCAAGCCTCAATGTGCGTGGCGCGCTG
GTGCAGATCGGCAAACACAAGATCAACCGCGACAATTGGGATTGGGATCAGGTCGACCAGAACCCGTTCTTCTGCCCTGA
TCCCGAGATGGTGCCCGTCTGGGAAGAGTATCTCGATGGTATCCGCAAGTCCGGCTCCTCCATCGGCGCGGTGGTCGAAG
TGGTGGCGGAAGGGGTTCCGGCCGGCATCGGCGCGCCGATCTATGCCAAGCTCGATCAGGATATCGCCTCCAGCCTGATG
TCGATCAACGCCGTCAAGGGCGTGGAGATCGGCGAAGGTTTTGCCTCGGCCGAGCTTTCCGGCGAGGAAAATGCCGACCA
GATGCGCATGGGCAATGACGGCAAGCCGATTTTCCTCTCCAACCATGCCGGCGGCATTCTGGGCGGCATCGCGACCGGTG
AGCCTGTTATCGCCCGCTTCGCCATCAAGCCCACCTCCTCCATCCTGACGGAGCGCCTGTCCATCGATACCGATGGCAAC
AATGTCGATGTGCGCACCAAGGGCCGCCACGACCCCTGCGTCGGCATCCGCGCCGTTCCGATCGGTGAAGCGATGATCGC
CTGCACCGTTGCCGACCATTACCTGAGAGACCGCGGCCAGACCGGCCGACTGAAATAA

Upstream 100 bases:

>100_bases
GAAAGAAAGGCTTTTGCCTTGCCCAGATTTTCCACTAAGACAAATCCGCTTGTTTTAAACGGCGCCGTCCACAGGCGCCC
TGTTTCCGGTCTTGAGAACT

Downstream 100 bases:

>100_bases
GGGGATATCGCCATGGCCTATGACCAGAAACGCGTTGTCGACGCCATCCGCGCATTCGAAGCCGGCGAAATCGTTGTCGT
GACCGATGATGACGACCGCG

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MSHNSFGHLFRVTTWGESHGPSLGCVVDGCPPGIRFTLAEVQHWMDKRKPGQSRFVTQRREDDIVKVLSGVMLDEDGETM
TTTGTPISMLIENTDQRSKDYGEIARRFRPGHADFTYDLKYGIRDYRGGGRSSARETAARVAAGAIARKVVPSLNVRGAL
VQIGKHKINRDNWDWDQVDQNPFFCPDPEMVPVWEEYLDGIRKSGSSIGAVVEVVAEGVPAGIGAPIYAKLDQDIASSLM
SINAVKGVEIGEGFASAELSGEENADQMRMGNDGKPIFLSNHAGGILGGIATGEPVIARFAIKPTSSILTERLSIDTDGN
NVDVRTKGRHDPCVGIRAVPIGEAMIACTVADHYLRDRGQTGRLK

Sequences:

>Translated_365_residues
MSHNSFGHLFRVTTWGESHGPSLGCVVDGCPPGIRFTLAEVQHWMDKRKPGQSRFVTQRREDDIVKVLSGVMLDEDGETM
TTTGTPISMLIENTDQRSKDYGEIARRFRPGHADFTYDLKYGIRDYRGGGRSSARETAARVAAGAIARKVVPSLNVRGAL
VQIGKHKINRDNWDWDQVDQNPFFCPDPEMVPVWEEYLDGIRKSGSSIGAVVEVVAEGVPAGIGAPIYAKLDQDIASSLM
SINAVKGVEIGEGFASAELSGEENADQMRMGNDGKPIFLSNHAGGILGGIATGEPVIARFAIKPTSSILTERLSIDTDGN
NVDVRTKGRHDPCVGIRAVPIGEAMIACTVADHYLRDRGQTGRLK
>Mature_364_residues
SHNSFGHLFRVTTWGESHGPSLGCVVDGCPPGIRFTLAEVQHWMDKRKPGQSRFVTQRREDDIVKVLSGVMLDEDGETMT
TTGTPISMLIENTDQRSKDYGEIARRFRPGHADFTYDLKYGIRDYRGGGRSSARETAARVAAGAIARKVVPSLNVRGALV
QIGKHKINRDNWDWDQVDQNPFFCPDPEMVPVWEEYLDGIRKSGSSIGAVVEVVAEGVPAGIGAPIYAKLDQDIASSLMS
INAVKGVEIGEGFASAELSGEENADQMRMGNDGKPIFLSNHAGGILGGIATGEPVIARFAIKPTSSILTERLSIDTDGNN
VDVRTKGRHDPCVGIRAVPIGEAMIACTVADHYLRDRGQTGRLK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=368, Percent_Identity=58.4239130434783, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=41.0326086956522, Blast_Score=268, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_AGRT5 (Q7D0R6)

Other databases:

- EMBL:   AE007869
- RefSeq:   NP_353778.2
- HSSP:   P28777
- ProteinModelPortal:   Q7D0R6
- STRING:   Q7D0R6
- GeneID:   1132792
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0754
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q7D0R6
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39634; Mature: 39503

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNSFGHLFRVTTWGESHGPSLGCVVDGCPPGIRFTLAEVQHWMDKRKPGQSRFVTQRR
CCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHH
EDDIVKVLSGVMLDEDGETMTTTGTPISMLIENTDQRSKDYGEIARRFRPGHADFTYDLK
HHHHHHHHHHHEECCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEE
YGIRDYRGGGRSSARETAARVAAGAIARKVVPSLNVRGALVQIGKHKINRDNWDWDQVDQ
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHCCC
NPFFCPDPEMVPVWEEYLDGIRKSGSSIGAVVEVVAEGVPAGIGAPIYAKLDQDIASSLM
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
SINAVKGVEIGEGFASAELSGEENADQMRMGNDGKPIFLSNHAGGILGGIATGEPVIARF
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCEEECCCCCCCEEEEE
AIKPTSSILTERLSIDTDGNNVDVRTKGRHDPCVGIRAVPIGEAMIACTVADHYLRDRGQ
EECCHHHHHHHHHEECCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCC
TGRLK
CCCCC
>Mature Secondary Structure 
SHNSFGHLFRVTTWGESHGPSLGCVVDGCPPGIRFTLAEVQHWMDKRKPGQSRFVTQRR
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHH
EDDIVKVLSGVMLDEDGETMTTTGTPISMLIENTDQRSKDYGEIARRFRPGHADFTYDLK
HHHHHHHHHHHEECCCCCEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEE
YGIRDYRGGGRSSARETAARVAAGAIARKVVPSLNVRGALVQIGKHKINRDNWDWDQVDQ
CCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHCCC
NPFFCPDPEMVPVWEEYLDGIRKSGSSIGAVVEVVAEGVPAGIGAPIYAKLDQDIASSLM
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
SINAVKGVEIGEGFASAELSGEENADQMRMGNDGKPIFLSNHAGGILGGIATGEPVIARF
HHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCEEECCCCCCCEEEEE
AIKPTSSILTERLSIDTDGNNVDVRTKGRHDPCVGIRAVPIGEAMIACTVADHYLRDRGQ
EECCHHHHHHHHHEECCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCC
TGRLK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194