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The map label for this gene is pgl [H]

Identifier: 159184382

GI number: 159184382

Start: 585140

End: 585838

Strand: Reverse

Name: pgl [H]

Synonym: Atu0599

Alternate gene names: 159184382

Gene position: 585838-585140 (Counterclockwise)

Preceding gene: 159184383

Following gene: 15887943

Centisome position: 20.62

GC content: 61.37

Gene sequence:

>699_bases
ATGAGCGAAACGATCCACGTCTTCGACACCGCCGCCGCGCTGGCCACCGCACTTGCGGCGGAGGTTGCCAAACGCCTTGA
TGCGGCGACCAAGGAACGGGGGACCGCCAGCATTGCGGTCTCAGGCGGCTCGACACCGAAGCTGTTTTTTCAGGCGCTTT
CCAGACACGATCTCGACTGGCCCAATATCAGCGTGACGCTGGTGGACGAGCGTTTCGTGCCGCCGGAAAGCGACCGTTCG
AACCATCGCCTCGTCGCGGACAATCTTTTGCAGGACAAGGCGAAGGCGGCCTATTTCGTGCCGCTGTTCCAGCCGGCTGC
CTCGCCGGAGGATGCGGCCACACTGGCGACCGTCAAGACCGAAGCGATCTGCGATCCTTTCGACGTCGTCATTCTCGGCA
TGGGAACGGATGGCCACACCGCATCGTTCTTCCCAGGTGGCGACAATCTCTACGAAGCGCTCGATCTCGATGAGCCGCGT
GGCGTGTTGACCATGGCAGCGGAGAATGCGGGGGAAGAGCGGTTGACCTTCAACTTCTCCAGCCTGCACGATGCCGATTT
TCTGGTGCTGCATATCGAAGGTGCGGCCAAGAAGGCGACGCTGGAGAAGGCACAATCGGGCGAGGATGAGGACGAAATGC
CTGTTCGCGCCGTGCTGAACCGGGCCGAAACGCCCGTGGATATATACTGGGCGCCATAA

Upstream 100 bases:

>100_bases
GTACAGGGTTACACTGCCGGCACCTGGGGCCCGAGCGGTTCGATCGCACTGATCGAGCGCGACGGCCGCACCTGGCACGA
TGCCGACTGAGGGCCGGGCG

Downstream 100 bases:

>100_bases
GCTAACGCGGTTGCCGCCTCTGCGGCCCGCGACAAGCGCCCGAAGACATGAAGACTGAAACACGACAACCGGCCGCTCAC
CTCCCGGAACGCTGGTTGCC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSETIHVFDTAAALATALAAEVAKRLDAATKERGTASIAVSGGSTPKLFFQALSRHDLDWPNISVTLVDERFVPPESDRS
NHRLVADNLLQDKAKAAYFVPLFQPAASPEDAATLATVKTEAICDPFDVVILGMGTDGHTASFFPGGDNLYEALDLDEPR
GVLTMAAENAGEERLTFNFSSLHDADFLVLHIEGAAKKATLEKAQSGEDEDEMPVRAVLNRAETPVDIYWAP

Sequences:

>Translated_232_residues
MSETIHVFDTAAALATALAAEVAKRLDAATKERGTASIAVSGGSTPKLFFQALSRHDLDWPNISVTLVDERFVPPESDRS
NHRLVADNLLQDKAKAAYFVPLFQPAASPEDAATLATVKTEAICDPFDVVILGMGTDGHTASFFPGGDNLYEALDLDEPR
GVLTMAAENAGEERLTFNFSSLHDADFLVLHIEGAAKKATLEKAQSGEDEDEMPVRAVLNRAETPVDIYWAP
>Mature_231_residues
SETIHVFDTAAALATALAAEVAKRLDAATKERGTASIAVSGGSTPKLFFQALSRHDLDWPNISVTLVDERFVPPESDRSN
HRLVADNLLQDKAKAAYFVPLFQPAASPEDAATLATVKTEAICDPFDVVILGMGTDGHTASFFPGGDNLYEALDLDEPRG
VLTMAAENAGEERLTFNFSSLHDADFLVLHIEGAAKKATLEKAQSGEDEDEMPVRAVLNRAETPVDIYWAP

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=218, Percent_Identity=28.4403669724771, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI115533060, Length=212, Percent_Identity=31.1320754716981, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115533058, Length=212, Percent_Identity=31.1320754716981, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321957, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321687, Length=180, Percent_Identity=28.8888888888889, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24986; Mature: 24855

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETIHVFDTAAALATALAAEVAKRLDAATKERGTASIAVSGGSTPKLFFQALSRHDLDW
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCC
PNISVTLVDERFVPPESDRSNHRLVADNLLQDKAKAAYFVPLFQPAASPEDAATLATVKT
CCEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHCCEEEEEEECCCCCCCCHHEEEEEEH
EAICDPFDVVILGMGTDGHTASFFPGGDNLYEALDLDEPRGVLTMAAENAGEERLTFNFS
HHCCCCCEEEEEEECCCCCEEEECCCCCCHHHHCCCCCCCCEEEEEECCCCCCEEEEEEC
SLHDADFLVLHIEGAAKKATLEKAQSGEDEDEMPVRAVLNRAETPVDIYWAP
CCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
SETIHVFDTAAALATALAAEVAKRLDAATKERGTASIAVSGGSTPKLFFQALSRHDLDW
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCCC
PNISVTLVDERFVPPESDRSNHRLVADNLLQDKAKAAYFVPLFQPAASPEDAATLATVKT
CCEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHCCEEEEEEECCCCCCCCHHEEEEEEH
EAICDPFDVVILGMGTDGHTASFFPGGDNLYEALDLDEPRGVLTMAAENAGEERLTFNFS
HHCCCCCEEEEEEECCCCCEEEECCCCCCHHHHCCCCCCCCEEEEEECCCCCCEEEEEEC
SLHDADFLVLHIEGAAKKATLEKAQSGEDEDEMPVRAVLNRAETPVDIYWAP
CCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]