Click here to switch to the map view.

The map label for this gene is mclA [C]

Identifier: 159184354

GI number: 159184354

Start: 515805

End: 517652

Strand: Direct

Name: mclA [C]

Synonym: Atu0526

Alternate gene names: 159184354

Gene position: 515805-517652 (Clockwise)

Preceding gene: 15887874

Following gene: 15887877

Centisome position: 18.15

GC content: 60.44

Gene sequence:

>1848_bases
ATGCACAACCGGCTCTTTAAGTCCGTTGCTGGCAAGGTCGTCGCGCTGACGATCGGCCTGATCACGCTCAGCGTGGCGGC
AGTTGGTTTTTCGACCTACATTCGCTTGAAGGACAACATCATCACCACCGCGCTGCGTGATACGCACGGCGCGATGCGGG
GCATGGCCATCCTTTACGAGATGAAGGTTGGCGGCGTTGCCCTCGAAATGGTGGATGGTGACCTGAAGAGTGTAGGCCGT
GCCAGCATCGGCACGATGCGCGACAACGATCTCGTAGACCGCACGGCTGCGGGCAACGGCGGTATCGCCACGGTTTTCGA
AGCCAAGGCCGGCGAATTCATTCGACTGACCACCAATCTGAAGAATGAAAAGGGTGAGAGAGCGGCAGGCACCAAGCTTG
CCACCGATCATCCGGCTTTCGAAAAAGTCTCCAAGGGCGAGGCCTATTTCGGCACTGCCACGCTGTTCGGCACCAGCTAC
ATGACCGGTTATATGCCGGTCACGAACAAGACCGGCGCAACCGTCGGCATCCTGTTCGTGGGTGTGCCCATGGATTTCTA
CAATGCGCAGATATACAGCCTGCGTGATATGATGGTGGTTTGCGGCGCGCTTGCCATGCTTGGCGTTGGATTACTCGCCT
ATTTCGTCATAAAGCGCACGCTTCAACCGCTTAGCAAGCTGACAGATGCCGTGAAATCGCTTTCGGACGGCGATCTCGAA
ACGCCGATCCCCTACGCCACCAACACCAATGAATTCGGCAATATCGCCCGCGCTCTGGTGATTTTCCGCGAGAATGCGAT
TGAGAAGCTGGCGATCGAGGGCAAAAGTGCGCAGGAACGCTCCGCGGCCGAGTCCGAGCGACACCGCAACGATGCCGAGA
AGCAGGAACTGGACGGCCAGATCGAGTTTGCAGTGGGCGAGATCGCCTCCGGCCTCGGCAGGCTTTCGCGTGGCGATCTG
AGCCGCACGATCGAGACGCCCTTTGCAGGCCGCCTCGACCGGCTGCGCACGGATTTCAACGAATCCTTGCTCAACCTTCG
CGATGCGCTGGGGCAGATCCGTGAGCGCACGCTCATCATTCAGAATAGTGGCATCGAAATCGAACAGTCTTCGGTCGATC
TGTCGAAACGCACGGAAAATCAGGCCGCCTCGCTGGAGGAGACCGCCGCTGCCGTGGAGGAGATCACCGCTACCGTGAGA
TCGTCGGCCGAGCGGGCACGGGAGGCAAATGAGGCCGTACGCGTCACCAAGCAGAGCGCCGACAGTTCCGGTTCGGTTGT
CAGCAATGCCGTCGACGCCATGAGCCGTATCGAAGGCGCCTCGCGCAAGATCGAGCAGATCATCGAGGTCATCGACGACA
TCGCCTTCCAGACCAATCTTCTCGCTCTCAATGCCGGCATTGAAGCGGCGCGCGCGGGTGAGGCGGGCAAGGGTTTTGCC
GTCGTGGCGCAGGAAGTGCGCGAACTTGCCCAGCGCTCTGCCGACGCAGCCCGTGAAATCAAGCAGCTCATCAACCAGTC
GACCCATGAGGTCAGCTCCGGTTCGAAGCTGGTGCAGGAGGCGGGCACCGTTCTCTCCGCCATCAGCCGGCAGATCGTGA
CTGTCAGCCAGCATGTCGAAACCATCGCGACGGCGACGCAGGACCAGTCCTCAGCCCTTCACAACGTCAACGGCTCCGTT
AACCAGATGGACCAGATGACGCAGCAGAATGCAGCGCTGGCCGAACAGTCGAGCGCGGCCAGCCGGGTACTTTCCGGCGA
AGTGGAGGCGCTGCTCGATCTGGTACAGCGGTTCCAGATGGAGCAGGGGTCTGCTGCCGGTTCGGGTCGATTGAACCGGG
CGGCCTGA

Upstream 100 bases:

>100_bases
GGGCTTTTGCACTCCGCTAAAAGGCGCCATCGGCACTTCGCGTTTTTTTAACAGTTGCCAATTAGAACTTTTTATAAGTT
TGGCTTTGGGGAACTGTTTC

Downstream 100 bases:

>100_bases
TCTCTCCATTTTTGAAAGTCAATGCAGCTCCCGGATCGCAAGGTCCGGGAGTTTTTATTCGGCCGCTGCCCGCGCCGTAC
CGGATATCTGGTTGATATAG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MHNRLFKSVAGKVVALTIGLITLSVAAVGFSTYIRLKDNIITTALRDTHGAMRGMAILYEMKVGGVALEMVDGDLKSVGR
ASIGTMRDNDLVDRTAAGNGGIATVFEAKAGEFIRLTTNLKNEKGERAAGTKLATDHPAFEKVSKGEAYFGTATLFGTSY
MTGYMPVTNKTGATVGILFVGVPMDFYNAQIYSLRDMMVVCGALAMLGVGLLAYFVIKRTLQPLSKLTDAVKSLSDGDLE
TPIPYATNTNEFGNIARALVIFRENAIEKLAIEGKSAQERSAAESERHRNDAEKQELDGQIEFAVGEIASGLGRLSRGDL
SRTIETPFAGRLDRLRTDFNESLLNLRDALGQIRERTLIIQNSGIEIEQSSVDLSKRTENQAASLEETAAAVEEITATVR
SSAERAREANEAVRVTKQSADSSGSVVSNAVDAMSRIEGASRKIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
VVAQEVRELAQRSADAAREIKQLINQSTHEVSSGSKLVQEAGTVLSAISRQIVTVSQHVETIATATQDQSSALHNVNGSV
NQMDQMTQQNAALAEQSSAASRVLSGEVEALLDLVQRFQMEQGSAAGSGRLNRAA

Sequences:

>Translated_615_residues
MHNRLFKSVAGKVVALTIGLITLSVAAVGFSTYIRLKDNIITTALRDTHGAMRGMAILYEMKVGGVALEMVDGDLKSVGR
ASIGTMRDNDLVDRTAAGNGGIATVFEAKAGEFIRLTTNLKNEKGERAAGTKLATDHPAFEKVSKGEAYFGTATLFGTSY
MTGYMPVTNKTGATVGILFVGVPMDFYNAQIYSLRDMMVVCGALAMLGVGLLAYFVIKRTLQPLSKLTDAVKSLSDGDLE
TPIPYATNTNEFGNIARALVIFRENAIEKLAIEGKSAQERSAAESERHRNDAEKQELDGQIEFAVGEIASGLGRLSRGDL
SRTIETPFAGRLDRLRTDFNESLLNLRDALGQIRERTLIIQNSGIEIEQSSVDLSKRTENQAASLEETAAAVEEITATVR
SSAERAREANEAVRVTKQSADSSGSVVSNAVDAMSRIEGASRKIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
VVAQEVRELAQRSADAAREIKQLINQSTHEVSSGSKLVQEAGTVLSAISRQIVTVSQHVETIATATQDQSSALHNVNGSV
NQMDQMTQQNAALAEQSSAASRVLSGEVEALLDLVQRFQMEQGSAAGSGRLNRAA
>Mature_615_residues
MHNRLFKSVAGKVVALTIGLITLSVAAVGFSTYIRLKDNIITTALRDTHGAMRGMAILYEMKVGGVALEMVDGDLKSVGR
ASIGTMRDNDLVDRTAAGNGGIATVFEAKAGEFIRLTTNLKNEKGERAAGTKLATDHPAFEKVSKGEAYFGTATLFGTSY
MTGYMPVTNKTGATVGILFVGVPMDFYNAQIYSLRDMMVVCGALAMLGVGLLAYFVIKRTLQPLSKLTDAVKSLSDGDLE
TPIPYATNTNEFGNIARALVIFRENAIEKLAIEGKSAQERSAAESERHRNDAEKQELDGQIEFAVGEIASGLGRLSRGDL
SRTIETPFAGRLDRLRTDFNESLLNLRDALGQIRERTLIIQNSGIEIEQSSVDLSKRTENQAASLEETAAAVEEITATVR
SSAERAREANEAVRVTKQSADSSGSVVSNAVDAMSRIEGASRKIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
VVAQEVRELAQRSADAAREIKQLINQSTHEVSSGSKLVQEAGTVLSAISRQIVTVSQHVETIATATQDQSSALHNVNGSV
NQMDQMTQQNAALAEQSSAASRVLSGEVEALLDLVQRFQMEQGSAAGSGRLNRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=253, Percent_Identity=47.0355731225296, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788195, Length=275, Percent_Identity=44, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1787690, Length=297, Percent_Identity=39.7306397306397, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1788194, Length=299, Percent_Identity=41.1371237458194, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1789453, Length=236, Percent_Identity=35.5932203389831, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 65769; Mature: 65769

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNRLFKSVAGKVVALTIGLITLSVAAVGFSTYIRLKDNIITTALRDTHGAMRGMAILYE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHEE
MKVGGVALEMVDGDLKSVGRASIGTMRDNDLVDRTAAGNGGIATVFEAKAGEFIRLTTNL
ECCCCEEEEEECCHHHHHCHHHCCCCCCCCHHHHCCCCCCCEEEEEECCCCCEEEEEECC
KNEKGERAAGTKLATDHPAFEKVSKGEAYFGTATLFGTSYMTGYMPVTNKTGATVGILFV
CCCCCCHHCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHHCCCEECCCCCCCEEEEEEE
GVPMDFYNAQIYSLRDMMVVCGALAMLGVGLLAYFVIKRTLQPLSKLTDAVKSLSDGDLE
ECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TPIPYATNTNEFGNIARALVIFRENAIEKLAIEGKSAQERSAAESERHRNDAEKQELDGQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHCCCC
IEFAVGEIASGLGRLSRGDLSRTIETPFAGRLDRLRTDFNESLLNLRDALGQIRERTLII
HHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
QNSGIEIEQSSVDLSKRTENQAASLEETAAAVEEITATVRSSAERAREANEAVRVTKQSA
ECCCCEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSSGSVVSNAVDAMSRIEGASRKIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHH
VVAQEVRELAQRSADAAREIKQLINQSTHEVSSGSKLVQEAGTVLSAISRQIVTVSQHVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIATATQDQSSALHNVNGSVNQMDQMTQQNAALAEQSSAASRVLSGEVEALLDLVQRFQM
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQGSAAGSGRLNRAA
HCCCCCCCCCCCCCC
>Mature Secondary Structure
MHNRLFKSVAGKVVALTIGLITLSVAAVGFSTYIRLKDNIITTALRDTHGAMRGMAILYE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHEE
MKVGGVALEMVDGDLKSVGRASIGTMRDNDLVDRTAAGNGGIATVFEAKAGEFIRLTTNL
ECCCCEEEEEECCHHHHHCHHHCCCCCCCCHHHHCCCCCCCEEEEEECCCCCEEEEEECC
KNEKGERAAGTKLATDHPAFEKVSKGEAYFGTATLFGTSYMTGYMPVTNKTGATVGILFV
CCCCCCHHCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHHCCCEECCCCCCCEEEEEEE
GVPMDFYNAQIYSLRDMMVVCGALAMLGVGLLAYFVIKRTLQPLSKLTDAVKSLSDGDLE
ECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TPIPYATNTNEFGNIARALVIFRENAIEKLAIEGKSAQERSAAESERHRNDAEKQELDGQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHCCCC
IEFAVGEIASGLGRLSRGDLSRTIETPFAGRLDRLRTDFNESLLNLRDALGQIRERTLII
HHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEE
QNSGIEIEQSSVDLSKRTENQAASLEETAAAVEEITATVRSSAERAREANEAVRVTKQSA
ECCCCEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSSGSVVSNAVDAMSRIEGASRKIEQIIEVIDDIAFQTNLLALNAGIEAARAGEAGKGFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHH
VVAQEVRELAQRSADAAREIKQLINQSTHEVSSGSKLVQEAGTVLSAISRQIVTVSQHVE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TIATATQDQSSALHNVNGSVNQMDQMTQQNAALAEQSSAASRVLSGEVEALLDLVQRFQM
HHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQGSAAGSGRLNRAA
HCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]