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The map label for this gene is dapB

Identifier: 159184200

GI number: 159184200

Start: 185768

End: 186595

Strand: Reverse

Name: dapB

Synonym: Atu0183

Alternate gene names: 159184200

Gene position: 186595-185768 (Counterclockwise)

Preceding gene: 159184201

Following gene: 15887535

Centisome position: 6.57

GC content: 63.77

Gene sequence:

>828_bases
ATGGGCAGCAGCGGCATGAAACTGGTGGTGGTCGGCGCAGCGGGCCGTATGGGACAGGCACTGATCCGTCTCATTCACCA
GACACCCGGCGTTCAGCTGCATGCCGCAGTGGCGCGTGAAGGTTCGGCTTTTGTTGGCCGCGATGCCGGCGAGATCGCCG
GTCTTGGCCCCATCGGCATCGAAATCACCAGCGATCCCTTACAGGCATTTCTGCATGCCGAAGGGGTGATCGATTTCACC
TCACCGGCAACCAGCATCACCTTTGCCGGCCTTGCCGCGCAGGCCCGTATCGTGCACGTCGTCGGCACGACTGGTTGCTC
GCCGCAAGACGAGGAAAAGTTCAAGGCGGCGTCGCGCCATGCCCGCATCGTCAAGTCAGGCAATATGAGCCTCGGCGTCA
ACCTGCTCAGCGTTCTCACCCAGCAGGCGGCGCAGGCGCTGGATGCGCAGAACTGGGATATCGAAATTCTGGAAATGCAC
CACAAGCACAAGGTCGATGCGCCCTCGGGCACCGCGCTGCTGCTGGGCGAAGCCGCCGCCGCCGGCCGCAAGGTCGATCT
CACCGCCGCCTCCGTGCGCGTGCGTGACGGACACACGGGCGCACGTGAGGCCGGTACCATCGGTTTTGCCACGCTGCGTG
GCGGCTCGGTCATCGGTGAACATTCGGTGATCTTCGCCGGCGAAGGCGAGCGCGTCGAGCTTTCCCATTATGCCGGCGAC
CGCTCCATCTTCGCACGCGGCGCGATCACGGCAGCAGTCTGGGCCTTCGACAAGAAGCCCGGTTTCTATTCCATGCTGGA
TGTGCTCGGCCTTTCGCAGGCGGAATAA

Upstream 100 bases:

>100_bases
TTGCGAAGCGGGCGGGCGATCTTTAACGTCGCTGCTGCAAACATCAATCGACCGATACCGGCGGGTTCCGATCCGCCTGA
CATGAAAAGTGAGTGAAAAC

Downstream 100 bases:

>100_bases
AACCGTACCCTAATTCTCCACCGTGAATTCGACCGTATCGGCAGAAAATCGGCTGACGGCATATTGCACCGGCACGCCAT
CCATATCGGCATTCAATGCC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MGSSGMKLVVVGAAGRMGQALIRLIHQTPGVQLHAAVAREGSAFVGRDAGEIAGLGPIGIEITSDPLQAFLHAEGVIDFT
SPATSITFAGLAAQARIVHVVGTTGCSPQDEEKFKAASRHARIVKSGNMSLGVNLLSVLTQQAAQALDAQNWDIEILEMH
HKHKVDAPSGTALLLGEAAAAGRKVDLTAASVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVIFAGEGERVELSHYAGD
RSIFARGAITAAVWAFDKKPGFYSMLDVLGLSQAE

Sequences:

>Translated_275_residues
MGSSGMKLVVVGAAGRMGQALIRLIHQTPGVQLHAAVAREGSAFVGRDAGEIAGLGPIGIEITSDPLQAFLHAEGVIDFT
SPATSITFAGLAAQARIVHVVGTTGCSPQDEEKFKAASRHARIVKSGNMSLGVNLLSVLTQQAAQALDAQNWDIEILEMH
HKHKVDAPSGTALLLGEAAAAGRKVDLTAASVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVIFAGEGERVELSHYAGD
RSIFARGAITAAVWAFDKKPGFYSMLDVLGLSQAE
>Mature_274_residues
GSSGMKLVVVGAAGRMGQALIRLIHQTPGVQLHAAVAREGSAFVGRDAGEIAGLGPIGIEITSDPLQAFLHAEGVIDFTS
PATSITFAGLAAQARIVHVVGTTGCSPQDEEKFKAASRHARIVKSGNMSLGVNLLSVLTQQAAQALDAQNWDIEILEMHH
KHKVDAPSGTALLLGEAAAAGRKVDLTAASVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVIFAGEGERVELSHYAGDR
SIFARGAITAAVWAFDKKPGFYSMLDVLGLSQAE

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=279, Percent_Identity=42.2939068100358, Blast_Score=204, Evalue=6e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_AGRT5 (Q8UIV8)

Other databases:

- EMBL:   AE007869
- PIR:   B97381
- RefSeq:   NP_353218.2
- ProteinModelPortal:   Q8UIV8
- SMR:   Q8UIV8
- STRING:   Q8UIV8
- GeneID:   1132221
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0183
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   Q8UIV8
- ProtClustDB:   PRK00048
- BioCyc:   ATUM176299-1:ATU0183-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28536; Mature: 28405

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSSGMKLVVVGAAGRMGQALIRLIHQTPGVQLHAAVAREGSAFVGRDAGEIAGLGPIGI
CCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCHHCCCCCCEE
EITSDPLQAFLHAEGVIDFTSPATSITFAGLAAQARIVHVVGTTGCSPQDEEKFKAASRH
EEECHHHHHHHHHCCEEEECCCCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHH
ARIVKSGNMSLGVNLLSVLTQQAAQALDAQNWDIEILEMHHKHKVDAPSGTALLLGEAAA
HEEEECCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCEEEEECHHC
AGRKVDLTAASVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVIFAGEGERVELSHYAGD
CCCEEEEEEEEEEEECCCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEEEECCCC
RSIFARGAITAAVWAFDKKPGFYSMLDVLGLSQAE
CCEEECCCCEEEEEEECCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
GSSGMKLVVVGAAGRMGQALIRLIHQTPGVQLHAAVAREGSAFVGRDAGEIAGLGPIGI
CCCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCCHHCCCCCCEE
EITSDPLQAFLHAEGVIDFTSPATSITFAGLAAQARIVHVVGTTGCSPQDEEKFKAASRH
EEECHHHHHHHHHCCEEEECCCCCEEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHH
ARIVKSGNMSLGVNLLSVLTQQAAQALDAQNWDIEILEMHHKHKVDAPSGTALLLGEAAA
HEEEECCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCCCCCCEEEEECHHC
AGRKVDLTAASVRVRDGHTGAREAGTIGFATLRGGSVIGEHSVIFAGEGERVELSHYAGD
CCCEEEEEEEEEEEECCCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEEEECCCC
RSIFARGAITAAVWAFDKKPGFYSMLDVLGLSQAE
CCEEECCCCEEEEEEECCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194