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The map label for this gene is panK

Identifier: 159184134

GI number: 159184134

Start: 39781

End: 40749

Strand: Reverse

Name: panK

Synonym: Atu0037

Alternate gene names: 159184134

Gene position: 40749-39781 (Counterclockwise)

Preceding gene: 159184135

Following gene: 159184131

Centisome position: 1.43

GC content: 56.86

Gene sequence:

>969_bases
ATGCCAGGCACACTCGATCATTTTCGTGCGGACGAATATTCGCCCTATCACTTCTTCAGTTCCGAAGAATGGGCCAAATT
CCGCGCTGACACGCCACTGACGCTTTCCGCCGATGAGGTGAAGCGGCTGCGATCGCTGGATGACCCCATCGATCTGGATG
AAGTGCGGCGCATTTACCTGTCGCTGTCGCGCCTCCTTTCATCGCATGTTGAAGCGTCGCAGCTGCTTTTCGAACAGCGC
AACCGCTTTCTGAATATGGGGGATGTCAACAAGACGCCCTTCGTCATCGGCATTGCCGGATCGGTGGCCGTTGGCAAATC
GACGACAGCGCGTATCCTGAAAGAGCTTCTGGCGCGGTGGCCTTCCAGCCCGAAGGTCGATCTCATCACCACTGACGGGT
TTCTTTACCCGAACGAGGTGCTGCGGCGCGAAAACCTGATGGAGCGCAAGGGCTTTCCGGAAAGCTACGATATCGGCGCG
CTGCTGCGTTTTCTTTCGGCGATCAAGGCGGGCCAGCCGAATGTGAAGGCCCCGCGTTATTCGCACCTGACCTACGACGT
GTTGCCGAACGAATTCACCGTCATCGACCAGCCGGATATCCTGATCTTCGAAGGCATCAACGTGCTGCAATCCCGTGACC
TTCCGGCGGGCGGTCGTATCGTGCCGATCGTTTCCGACTTCTTCGATTTCTCGATCTATATCGATGCCGATGAGGATTTC
ATTCACAACTGGTATGTGAACCGGTTCATGAACCTGAGACAGACCGCCTTCCGCGACCCGAACTCATTCTTCAACCGGTA
TGCGTCGATCAGCGAAGAGGCGGCACTCAGCATTGCCGAAGGGCTCTGGCAGAACATCAACCTGAAGAACCTGCGCCAGA
ACATCGTGCCGACGCGCCCGCGCGCCGATCTTATTCTGCGCAAGGGAGAGAACCACCTGATAGATACGGTGGCGCTGCGA
AAGCTCTGA

Upstream 100 bases:

>100_bases
TTTTTGCCGAACTGGAGCGTCGCACAGGTCAGACCGGCCTTGCGGAAAAGGCGGCGAGGCCGACACCATGAAGATTGAGG
CGGGCAGCGGGGAGAGAGGC

Downstream 100 bases:

>100_bases
CAAACTGGGTGCTTGCGGGTTAATCGCCCGAGGGTTTGCCGCGCATTTTCTTGATATCGGAACGACCGGATTTTGCCTTG
AGGCGGCGTTCGACAGATCC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MPGTLDHFRADEYSPYHFFSSEEWAKFRADTPLTLSADEVKRLRSLDDPIDLDEVRRIYLSLSRLLSSHVEASQLLFEQR
NRFLNMGDVNKTPFVIGIAGSVAVGKSTTARILKELLARWPSSPKVDLITTDGFLYPNEVLRRENLMERKGFPESYDIGA
LLRFLSAIKAGQPNVKAPRYSHLTYDVLPNEFTVIDQPDILIFEGINVLQSRDLPAGGRIVPIVSDFFDFSIYIDADEDF
IHNWYVNRFMNLRQTAFRDPNSFFNRYASISEEAALSIAEGLWQNINLKNLRQNIVPTRPRADLILRKGENHLIDTVALR
KL

Sequences:

>Translated_322_residues
MPGTLDHFRADEYSPYHFFSSEEWAKFRADTPLTLSADEVKRLRSLDDPIDLDEVRRIYLSLSRLLSSHVEASQLLFEQR
NRFLNMGDVNKTPFVIGIAGSVAVGKSTTARILKELLARWPSSPKVDLITTDGFLYPNEVLRRENLMERKGFPESYDIGA
LLRFLSAIKAGQPNVKAPRYSHLTYDVLPNEFTVIDQPDILIFEGINVLQSRDLPAGGRIVPIVSDFFDFSIYIDADEDF
IHNWYVNRFMNLRQTAFRDPNSFFNRYASISEEAALSIAEGLWQNINLKNLRQNIVPTRPRADLILRKGENHLIDTVALR
KL
>Mature_321_residues
PGTLDHFRADEYSPYHFFSSEEWAKFRADTPLTLSADEVKRLRSLDDPIDLDEVRRIYLSLSRLLSSHVEASQLLFEQRN
RFLNMGDVNKTPFVIGIAGSVAVGKSTTARILKELLARWPSSPKVDLITTDGFLYPNEVLRRENLMERKGFPESYDIGAL
LRFLSAIKAGQPNVKAPRYSHLTYDVLPNEFTVIDQPDILIFEGINVLQSRDLPAGGRIVPIVSDFFDFSIYIDADEDFI
HNWYVNRFMNLRQTAFRDPNSFFNRYASISEEAALSIAEGLWQNINLKNLRQNIVPTRPRADLILRKGENHLIDTVALRK
L

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=312, Percent_Identity=52.2435897435897, Blast_Score=324, Evalue=4e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_AGRT5 (Q8UJ92)

Other databases:

- EMBL:   AE007869
- PIR:   AF2581
- PIR:   D97363
- RefSeq:   NP_353076.2
- ProteinModelPortal:   Q8UJ92
- SMR:   Q8UJ92
- STRING:   Q8UJ92
- GeneID:   1132075
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0037
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- PhylomeDB:   Q8UJ92
- ProtClustDB:   PRK05439
- BioCyc:   ATUM176299-1:ATU0037-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 36937; Mature: 36806

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGTLDHFRADEYSPYHFFSSEEWAKFRADTPLTLSADEVKRLRSLDDPIDLDEVRRIYL
CCCCCCCCCCCCCCCCEECCCCHHHHHCCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHH
SLSRLLSSHVEASQLLFEQRNRFLNMGDVNKTPFVIGIAGSVAVGKSTTARILKELLARW
HHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHC
PSSPKVDLITTDGFLYPNEVLRRENLMERKGFPESYDIGALLRFLSAIKAGQPNVKAPRY
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
SHLTYDVLPNEFTVIDQPDILIFEGINVLQSRDLPAGGRIVPIVSDFFDFSIYIDADEDF
CCCEEEECCCCEEEECCCCEEEECCCHHHHCCCCCCCCEEEHEECCCCCEEEEEECCHHH
IHNWYVNRFMNLRQTAFRDPNSFFNRYASISEEAALSIAEGLWQNINLKNLRQNIVPTRP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
RADLILRKGENHLIDTVALRKL
CHHEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure 
PGTLDHFRADEYSPYHFFSSEEWAKFRADTPLTLSADEVKRLRSLDDPIDLDEVRRIYL
CCCCCCCCCCCCCCCEECCCCHHHHHCCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHH
SLSRLLSSHVEASQLLFEQRNRFLNMGDVNKTPFVIGIAGSVAVGKSTTARILKELLARW
HHHHHHHHHHHHHHHHHHHHHCEECCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHC
PSSPKVDLITTDGFLYPNEVLRRENLMERKGFPESYDIGALLRFLSAIKAGQPNVKAPRY
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
SHLTYDVLPNEFTVIDQPDILIFEGINVLQSRDLPAGGRIVPIVSDFFDFSIYIDADEDF
CCCEEEECCCCEEEECCCCEEEECCCHHHHCCCCCCCCEEEHEECCCCCEEEEEECCHHH
IHNWYVNRFMNLRQTAFRDPNSFFNRYASISEEAALSIAEGLWQNINLKNLRQNIVPTRP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCC
RADLILRKGENHLIDTVALRKL
CHHEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194