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The map label for this gene is cobH [H]

Identifier: 15890049

GI number: 15890049

Start: 2802992

End: 2803624

Strand: Reverse

Name: cobH [H]

Synonym: Atu2802

Alternate gene names: 15890049

Gene position: 2803624-2802992 (Counterclockwise)

Preceding gene: 159185389

Following gene: 15890048

Centisome position: 98.66

GC content: 59.24

Gene sequence:

>633_bases
ATGACCGACTATGATTATATTCGCGATGGCAATGCGATCTATGAGCGCTCTTTCGCCATTATTCGCGAGGAAGCGGATTT
ATCCGCCTTTACCGAAGAGCAGGCGGATATCGCCATTCGCATGATCCATGCCTGCGGGCAGGTGGAGGCGGCAGGCCATT
TCCGCTTTTCGCCGGATTTCGTTTCGGCCGCGCGGGGCGCCTTGCTCGCCGGCAAACCCGTTCTGTGTGATGCGCAAATG
GTTGCCCATGGCGTGACGCATGCAAGACTTCCGGCTGATAATGCTGTCATCTGCACGCTTCGCGATCCACGCACGCCGGA
GCTTGCGAAAAACATCGGCAACACCCGCTCGGCTGCTGCGCTCGATCTCTGGGCGGATTATCTCGACGGTGCCTTGGTCG
CTATAGGCAACGCGCCAACGGCTTTGTTTTATCTTCTGGAAATGCTGGAAAAAGGCGGCCCGCGTCCGGCTGCCATCATC
GGTATGCCGGTTGGTTTTGTCGGTGCGGCGGAATCGAAAGATGCGCTGGAGGCAAGTGCGCTTGGCATTCCCTATGCTAT
CGTCAAGGGACGTTTGGGCGGCTCGGCCATGACGGCCGCCGCCATCAACGCGGTTGCGAGGGCGGGCCTGTGA

Upstream 100 bases:

>100_bases
GTCTTTACGAAAAAGAACATAAGCCCGGTGAAAACGCCGCCATCTTTTTTGCCCGTCTGGGCCGGGAGGAAATCGGTGCG
GCGCTTCGACAGGATAACCA

Downstream 100 bases:

>100_bases
GTGCTGCGCTTTTTGAACATGCCAAGGGTAAGCTTGTCGGCGTCGGCACTGGTCCGGGTGATCCTGAGCTGCTGACGCTG
AAAGCCGTGCGCGCCATCGA

Product: precorrin-8X methylmutase

Products: NA

Alternate protein names: HBA synthase; Precorrin isomerase [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MTDYDYIRDGNAIYERSFAIIREEADLSAFTEEQADIAIRMIHACGQVEAAGHFRFSPDFVSAARGALLAGKPVLCDAQM
VAHGVTHARLPADNAVICTLRDPRTPELAKNIGNTRSAAALDLWADYLDGALVAIGNAPTALFYLLEMLEKGGPRPAAII
GMPVGFVGAAESKDALEASALGIPYAIVKGRLGGSAMTAAAINAVARAGL

Sequences:

>Translated_210_residues
MTDYDYIRDGNAIYERSFAIIREEADLSAFTEEQADIAIRMIHACGQVEAAGHFRFSPDFVSAARGALLAGKPVLCDAQM
VAHGVTHARLPADNAVICTLRDPRTPELAKNIGNTRSAAALDLWADYLDGALVAIGNAPTALFYLLEMLEKGGPRPAAII
GMPVGFVGAAESKDALEASALGIPYAIVKGRLGGSAMTAAAINAVARAGL
>Mature_209_residues
TDYDYIRDGNAIYERSFAIIREEADLSAFTEEQADIAIRMIHACGQVEAAGHFRFSPDFVSAARGALLAGKPVLCDAQMV
AHGVTHARLPADNAVICTLRDPRTPELAKNIGNTRSAAALDLWADYLDGALVAIGNAPTALFYLLEMLEKGGPRPAAIIG
MPVGFVGAAESKDALEASALGIPYAIVKGRLGGSAMTAAAINAVARAGL

Specific function: Catalyzes the conversion of precorrin-8X to hydrogenobyrinic acid; a methyl migration reaction during the transformation of precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: =5.4.1.2 [H]

Molecular weight: Translated: 21999; Mature: 21868

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDYDYIRDGNAIYERSFAIIREEADLSAFTEEQADIAIRMIHACGQVEAAGHFRFSPDF
CCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCHH
VSAARGALLAGKPVLCDAQMVAHGVTHARLPADNAVICTLRDPRTPELAKNIGNTRSAAA
HHHHCCCEECCCCCEECHHHHHHCCHHCCCCCCCEEEEEECCCCCHHHHHHCCCCCCHHH
LDLWADYLDGALVAIGNAPTALFYLLEMLEKGGPRPAAIIGMPVGFVGAAESKDALEASA
HHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
LGIPYAIVKGRLGGSAMTAAAINAVARAGL
CCCCHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDYDYIRDGNAIYERSFAIIREEADLSAFTEEQADIAIRMIHACGQVEAAGHFRFSPDF
CCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCHH
VSAARGALLAGKPVLCDAQMVAHGVTHARLPADNAVICTLRDPRTPELAKNIGNTRSAAA
HHHHCCCEECCCCCEECHHHHHHCCHHCCCCCCCEEEEEECCCCCHHHHHHCCCCCCHHH
LDLWADYLDGALVAIGNAPTALFYLLEMLEKGGPRPAAIIGMPVGFVGAAESKDALEASA
HHHHHHHHCCEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHH
LGIPYAIVKGRLGGSAMTAAAINAVARAGL
CCCCHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732194 [H]