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The map label for this gene is ccmB [H]

Identifier: 15889942

GI number: 15889942

Start: 2672036

End: 2672695

Strand: Direct

Name: ccmB [H]

Synonym: Atu2687

Alternate gene names: 15889942

Gene position: 2672036-2672695 (Clockwise)

Preceding gene: 15889941

Following gene: 15889943

Centisome position: 94.03

GC content: 62.73

Gene sequence:

>660_bases
ATGACCGTCCTCTTCCTCCGCGACATCAAACTCTCCATCCGCGCCGGCGGCGGTGCGCTGATCGGCGTGCTGTTCTTCAT
GACCGTGGTTGCCGTTATCCCCTTTGGCGTCGGCCCCGATCTCAACCTGCTCGCCCGCATCGGCCCCGCCATCGTCTGGA
TCGGCGCGCTTCTGTCCGCCCTTCTCGGCCTCGACCGGCTGTTTCAGGCTGAACGGGATGACGGCTCTCTCGATCTGATC
TTGATGCAGGAAACCCCGCTGGTACTGACCGTCTTCGTCAAATGTCTGGCGCATTGGGTGGGAACCGGCCTGCCGCTGGT
GCTGGCATCACCGTTGCTCGGCCTGTTCATGAACATGGACGAGGTGGCGATCGGTGCCGTGATGCTCACGCTTCTCGTCG
GCTCACCCGCCATCACCTTCATCGGCGCGGTGGGCGCGGCGGTTGCCGTTGCCCTGCCGCGAGGTGGCCTTCTGGTTTCC
ATCCTCGTCCTGCCGCTCGCCATTCCGGTGCTGATCTTCGGCGTCAGCGCTTCCTATGCGGCGGTGCAGGACCCCGCGCC
CTTCATGCCGCCATTTTTCATTCTCTGCGCGATCACGTTATTTTCAGCCGTGACCGGCCCTTTCTTTGCCGCTTTGGCAC
TGCGCAATGTTATGGATTGA

Upstream 100 bases:

>100_bases
TGAGATGGGCGAGACTTATCCGCATATCGATCTCCGTCCTTGAGGGGGAGATGCCCGGCAGGGCAAAGGGGGGTAAGGCC
CCAGACGCGGAGCGACCCCA

Downstream 100 bases:

>100_bases
CGAAACCGTGATGGATGATCCCCTGTTGACAGGGATCAATTGCGGGGCGGCCATTCTCGGGTTACACAAACGGCATGAAC
GAGCAGATCTTCACCATCAC

Product: ABC transporter, membrane spanning protein (heme)

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTVLFLRDIKLSIRAGGGALIGVLFFMTVVAVIPFGVGPDLNLLARIGPAIVWIGALLSALLGLDRLFQAERDDGSLDLI
LMQETPLVLTVFVKCLAHWVGTGLPLVLASPLLGLFMNMDEVAIGAVMLTLLVGSPAITFIGAVGAAVAVALPRGGLLVS
ILVLPLAIPVLIFGVSASYAAVQDPAPFMPPFFILCAITLFSAVTGPFFAALALRNVMD

Sequences:

>Translated_219_residues
MTVLFLRDIKLSIRAGGGALIGVLFFMTVVAVIPFGVGPDLNLLARIGPAIVWIGALLSALLGLDRLFQAERDDGSLDLI
LMQETPLVLTVFVKCLAHWVGTGLPLVLASPLLGLFMNMDEVAIGAVMLTLLVGSPAITFIGAVGAAVAVALPRGGLLVS
ILVLPLAIPVLIFGVSASYAAVQDPAPFMPPFFILCAITLFSAVTGPFFAALALRNVMD
>Mature_218_residues
TVLFLRDIKLSIRAGGGALIGVLFFMTVVAVIPFGVGPDLNLLARIGPAIVWIGALLSALLGLDRLFQAERDDGSLDLIL
MQETPLVLTVFVKCLAHWVGTGLPLVLASPLLGLFMNMDEVAIGAVMLTLLVGSPAITFIGAVGAAVAVALPRGGLLVSI
LVLPLAIPVLIFGVSASYAAVQDPAPFMPPFFILCAITLFSAVTGPFFAALALRNVMD

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=212, Percent_Identity=42.4528301886792, Blast_Score=117, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22808; Mature: 22677

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLFLRDIKLSIRAGGGALIGVLFFMTVVAVIPFGVGPDLNLLARIGPAIVWIGALLSA
CEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLGLDRLFQAERDDGSLDLILMQETPLVLTVFVKCLAHWVGTGLPLVLASPLLGLFMNMD
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHH
EVAIGAVMLTLLVGSPAITFIGAVGAAVAVALPRGGLLVSILVLPLAIPVLIFGVSASYA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
AVQDPAPFMPPFFILCAITLFSAVTGPFFAALALRNVMD
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVLFLRDIKLSIRAGGGALIGVLFFMTVVAVIPFGVGPDLNLLARIGPAIVWIGALLSA
EEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLGLDRLFQAERDDGSLDLILMQETPLVLTVFVKCLAHWVGTGLPLVLASPLLGLFMNMD
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHH
EVAIGAVMLTLLVGSPAITFIGAVGAAVAVALPRGGLLVSILVLPLAIPVLIFGVSASYA
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHH
AVQDPAPFMPPFFILCAITLFSAVTGPFFAALALRNVMD
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]