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The map label for this gene is atpC

Identifier: 15889876

GI number: 15889876

Start: 2604175

End: 2604585

Strand: Reverse

Name: atpC

Synonym: Atu2621

Alternate gene names: 15889876

Gene position: 2604585-2604175 (Counterclockwise)

Preceding gene: 159185297

Following gene: 159185296

Centisome position: 91.66

GC content: 54.74

Gene sequence:

>411_bases
ATGGCTGACAGTTTCAAATTCGATCTCGTTTCCCCGGAGCGTCTGCTCGTTTCCGAAACGGTTACGGAAGTCGTCATCCC
GGCTACGCTGGGTGAAATGACCGTTCTGGCCAATCATGCGCCGACGATGACCACGATCAAGCCGGGTCTGGTGACGGTGA
AGTTCGCCTCTGGCGAAACGCACAAATACGTCGTGTTCGGCGGTTTTGCCGATATTCTTCCGACAGGTTGCACGCTTCTC
GCCGAATCCGCTGTTTCGGCTGACGATATGTCTCCTGATACGCTGCAGAAGCGCATCGATGCGGCCAAGGCCGAAATCCA
GGAAGGCAATCATCACCACGAGCATCTTACCAAGCTTGAAAAGCACCTCTATGAGCTGACGAACCTGCATGAGGTTCTCG
TCGCTGCTTGA

Upstream 100 bases:

>100_bases
GCGCCTTCCGACCAATGACAGCGAAACCGAAATGGCTTTCGCCTGCGTTGTTAAAAGACAAGTCCGTGACGCCCGCGTAA
TTGAAAAGAAGTGAATAGCC

Downstream 100 bases:

>100_bases
AAGCACCGGGCGGGTTCGAAAGAATGACTGCCCACAAAATATTTAAAACAGAAAGCGGCCGTTTCGGTCGCTTTTTTGTT
TTCAGCTGTCTCCTGCTTCT

Product: F0F1 ATP synthase subunit epsilon

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MADSFKFDLVSPERLLVSETVTEVVIPATLGEMTVLANHAPTMTTIKPGLVTVKFASGETHKYVVFGGFADILPTGCTLL
AESAVSADDMSPDTLQKRIDAAKAEIQEGNHHHEHLTKLEKHLYELTNLHEVLVAA

Sequences:

>Translated_136_residues
MADSFKFDLVSPERLLVSETVTEVVIPATLGEMTVLANHAPTMTTIKPGLVTVKFASGETHKYVVFGGFADILPTGCTLL
AESAVSADDMSPDTLQKRIDAAKAEIQEGNHHHEHLTKLEKHLYELTNLHEVLVAA
>Mature_135_residues
ADSFKFDLVSPERLLVSETVTEVVIPATLGEMTVLANHAPTMTTIKPGLVTVKFASGETHKYVVFGGFADILPTGCTLLA
ESAVSADDMSPDTLQKRIDAAKAEIQEGNHHHEHLTKLEKHLYELTNLHEVLVAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family

Homologues:

Organism=Escherichia coli, GI1790169, Length=90, Percent_Identity=30, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPE_AGRT5 (Q8UC77)

Other databases:

- EMBL:   AE007869
- PIR:   AD2898
- PIR:   E97673
- RefSeq:   NP_355557.1
- ProteinModelPortal:   Q8UC77
- SMR:   Q8UC77
- STRING:   Q8UC77
- GeneID:   1134659
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2621
- eggNOG:   COG0355
- HOGENOM:   HBG663981
- OMA:   HAPTMTT
- PhylomeDB:   Q8UC77
- ProtClustDB:   PRK00571
- BioCyc:   ATUM176299-1:ATU2621-MONOMER
- HAMAP:   MF_00530
- InterPro:   IPR001469
- InterPro:   IPR020546
- Gene3D:   G3DSA:2.60.15.10
- PANTHER:   PTHR13822
- ProDom:   PD000944
- TIGRFAMs:   TIGR01216

Pfam domain/function: PF02823 ATP-synt_DE_N; SSF51344 ATPsynt_DE

EC number: 3.6.3.14

Molecular weight: Translated: 14764; Mature: 14633

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSFKFDLVSPERLLVSETVTEVVIPATLGEMTVLANHAPTMTTIKPGLVTVKFASGET
CCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCEEEEEECCCCC
HKYVVFGGFADILPTGCTLLAESAVSADDMSPDTLQKRIDAAKAEIQEGNHHHEHLTKLE
EEEEEECCHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KHLYELTNLHEVLVAA
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADSFKFDLVSPERLLVSETVTEVVIPATLGEMTVLANHAPTMTTIKPGLVTVKFASGET
CCCCEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCEEEEEECCCCC
HKYVVFGGFADILPTGCTLLAESAVSADDMSPDTLQKRIDAAKAEIQEGNHHHEHLTKLE
EEEEEECCHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KHLYELTNLHEVLVAA
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194