Click here to switch to the map view.

The map label for this gene is yafC [C]

Identifier: 15889471

GI number: 15889471

Start: 2166746

End: 2167690

Strand: Direct

Name: yafC [C]

Synonym: Atu2191

Alternate gene names: 15889471

Gene position: 2166746-2167690 (Clockwise)

Preceding gene: 15889468

Following gene: 159185098

Centisome position: 76.25

GC content: 62.43

Gene sequence:

>945_bases
ATGACCAAAAGCCGGGATGTCAGCTGGGATTTTTACCGCACCTTCCTCAGCGTGCTGCGTGACGGCTCGCTTTCCGCCGC
CGCGCGCGAGCTCGGTATCACGCAGCCGACGGCGGGGCGGCACATTGGTGCGCTGGAAGAGGCCGTCGGATTTCCGCTGT
TCATCCGCTCCCCGCACGGGCTGATGCCGACGGAGGCCGCCCTGGCGCTCAGGCCCTATGCGGAAAATCTGGCGGCGACG
GCGGCCGCCCTCATGCGCGCGGCCTCCGGCGAGGTCGGCAAGATCGAAGGCACCGTGCGCATCAGCGCATCGGATATTAT
CGGCGTGGAAATGCTGCCACCGATCGTCGCCCTGATGCAGGAGGTCCACCCCCGGCTGGAAATTGAGCTTTCTCTCTCCG
ATACGCTGGAAGACCTGTTGCGGCGTGAGGCCGACATCGCCATCCGCATGACCGAACCGCAGCAGGATGCGATCGTCATG
CGCTACATCGGCAATTTCCGCCTCGGATTTCATGCGACGCGCGACTATCTGGCAAAAGCCGGCATTCCAAAAGCCATGGA
AGAACTGAACGAGCACCGGATGGTCGGTTTCGACCGCAAGACGCCCTTCATCCGGGCGGCTATCCAGCGGATGCGTTCGC
TTGATCCCGACATACCCGATATTGAAGATATTTCCTTCGAAATCCGCGCCGACAGCAACCTCGCCCAGCTTGCCATGATC
CGCGCCAGCGCGGGTATCGGCGTCTGCCAGATCGGCCTGGCGCGCAAGGACCCCCGGCTAGTCCACGTTCTTCCAGATAT
CGATATTCCGCTGCACACCTGGGTGGCGATGCACGAAAACCTCAAGACCTCGCCGCGGTGCCGTGCCGTTTTCAGTGCTC
TCGTCGAGGGTCTGAAAGCCCATCTCAAGGAAACCGATCCGAACGCCCCGCCAAAACGGCGTTAG

Upstream 100 bases:

>100_bases
CATATATCATCGCAGTTACTCCTTCTTCTGAACTGGAGTATCGGCGTGATGTGCGATATACGAAATTGTCGAAATAGGTG
GAGCGGCCATACAAAATTTT

Downstream 100 bases:

>100_bases
AGTTTGTCCATTCACAGCGGACCGGAGGTGCGTGGAGCTTTACCCCCCTCTGCCCTGCCGGGCATCTCCCCCTCAAGGGG
GGAGATCGGCAAGAGGCCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MTKSRDVSWDFYRTFLSVLRDGSLSAAARELGITQPTAGRHIGALEEAVGFPLFIRSPHGLMPTEAALALRPYAENLAAT
AAALMRAASGEVGKIEGTVRISASDIIGVEMLPPIVALMQEVHPRLEIELSLSDTLEDLLRREADIAIRMTEPQQDAIVM
RYIGNFRLGFHATRDYLAKAGIPKAMEELNEHRMVGFDRKTPFIRAAIQRMRSLDPDIPDIEDISFEIRADSNLAQLAMI
RASAGIGVCQIGLARKDPRLVHVLPDIDIPLHTWVAMHENLKTSPRCRAVFSALVEGLKAHLKETDPNAPPKRR

Sequences:

>Translated_314_residues
MTKSRDVSWDFYRTFLSVLRDGSLSAAARELGITQPTAGRHIGALEEAVGFPLFIRSPHGLMPTEAALALRPYAENLAAT
AAALMRAASGEVGKIEGTVRISASDIIGVEMLPPIVALMQEVHPRLEIELSLSDTLEDLLRREADIAIRMTEPQQDAIVM
RYIGNFRLGFHATRDYLAKAGIPKAMEELNEHRMVGFDRKTPFIRAAIQRMRSLDPDIPDIEDISFEIRADSNLAQLAMI
RASAGIGVCQIGLARKDPRLVHVLPDIDIPLHTWVAMHENLKTSPRCRAVFSALVEGLKAHLKETDPNAPPKRR
>Mature_313_residues
TKSRDVSWDFYRTFLSVLRDGSLSAAARELGITQPTAGRHIGALEEAVGFPLFIRSPHGLMPTEAALALRPYAENLAATA
AALMRAASGEVGKIEGTVRISASDIIGVEMLPPIVALMQEVHPRLEIELSLSDTLEDLLRREADIAIRMTEPQQDAIVMR
YIGNFRLGFHATRDYLAKAGIPKAMEELNEHRMVGFDRKTPFIRAAIQRMRSLDPDIPDIEDISFEIRADSNLAQLAMIR
ASAGIGVCQIGLARKDPRLVHVLPDIDIPLHTWVAMHENLKTSPRCRAVFSALVEGLKAHLKETDPNAPPKRR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=187, Percent_Identity=26.7379679144385, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=23.4323432343234, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1789440, Length=305, Percent_Identity=21.9672131147541, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693193, Length=259, Percent_Identity=24.3243243243243, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34737; Mature: 34606

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSRDVSWDFYRTFLSVLRDGSLSAAARELGITQPTAGRHIGALEEAVGFPLFIRSPHG
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCC
LMPTEAALALRPYAENLAATAAALMRAASGEVGKIEGTVRISASDIIGVEMLPPIVALMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
EVHPRLEIELSLSDTLEDLLRREADIAIRMTEPQQDAIVMRYIGNFRLGFHATRDYLAKA
HCCCCEEEEEEHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHC
GIPKAMEELNEHRMVGFDRKTPFIRAAIQRMRSLDPDIPDIEDISFEIRADSNLAQLAMI
CCHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHH
RASAGIGVCQIGLARKDPRLVHVLPDIDIPLHTWVAMHENLKTSPRCRAVFSALVEGLKA
HHCCCCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
HLKETDPNAPPKRR
HHHCCCCCCCCCCC
>Mature Secondary Structure 
TKSRDVSWDFYRTFLSVLRDGSLSAAARELGITQPTAGRHIGALEEAVGFPLFIRSPHG
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEECCCC
LMPTEAALALRPYAENLAATAAALMRAASGEVGKIEGTVRISASDIIGVEMLPPIVALMQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHH
EVHPRLEIELSLSDTLEDLLRREADIAIRMTEPQQDAIVMRYIGNFRLGFHATRDYLAKA
HCCCCEEEEEEHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHC
GIPKAMEELNEHRMVGFDRKTPFIRAAIQRMRSLDPDIPDIEDISFEIRADSNLAQLAMI
CCHHHHHHHHHHCEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHH
RASAGIGVCQIGLARKDPRLVHVLPDIDIPLHTWVAMHENLKTSPRCRAVFSALVEGLKA
HHCCCCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
HLKETDPNAPPKRR
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]