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The map label for this gene is prmA

Identifier: 15889356

GI number: 15889356

Start: 2033135

End: 2034013

Strand: Reverse

Name: prmA

Synonym: Atu2072

Alternate gene names: 15889356

Gene position: 2034013-2033135 (Counterclockwise)

Preceding gene: 15889357

Following gene: 159185037

Centisome position: 71.58

GC content: 60.98

Gene sequence:

>879_bases
GTGAGCGAAATCCGCCTCTATGTCACCACGACCGAAATCAAGGCCGGTGAAATCCTCGATCTCATGTCGGACTATTTCGG
CGAGGAGGATGTCGCGATCGCCACGACCGAGGTGGATGAGAAGCGCGACATCTGGGAAGCCTCCGTCTATCTGATGGCGG
AGCAGGAGGAGGAGTTCCGCGAGCGCGTCAGCACTTTGCTTGCCCCCGCCTTTCCCGGTCTCGTCATTGAGAAGGAAATC
ATTCCCGATGTCGACTGGATCGCCAAATCGCTCGAGGGGCTGAAGCCGGTGCGGGCAGGGCGGTTCATCGTCCATGGCGC
GCATGATCGCGACAAGGTGCAGCCGCACGATCTGGCGATCGAGATCGAGGCGGGGCAGGCTTTCGGCACCGGCCATCACG
GCACCACGGCCGGCTGCCTTGAAATGATTGAGGACGTGCTCCGTGCACGGAAGGTGCGCAACGCGCTCGATCTCGGCACC
GGCAGCGGTGTGCTGGCGATTGCGGTGCGCAAGATGCGTCCCATTCCCGTGCTGGCAACGGACATCGATCCCATTGCCGT
CAAGGTGGCCAAGGAAAATGTACGGCTGAACGGCATTGTTTCCGGGATGGCGCTGGAAACCGCACCGGGTTTCCACTCAG
ATGCTTTCCGCAAGCATGGTCCGTTCGATCTCATCATCGCCAATATTCTGGCGCGGCCGCTCATCAAGATGGCGCCGCAG
CTCGTCACGCATCTGGCGCCCGGCGGCACCGTCATCCTGTCGGGCATTCTTGCATCGCAGCGCTGGAAGGTGCTTTCCGC
GTATAATGGCGCCAAGCTTTCCCATATCCGCACCATCTGGCGCAATGACTGGGTAACGCTGCATCTGCGCAAGGACTGA

Upstream 100 bases:

>100_bases
CTTAAAGGCGCGAAGGCATAATTACGCCGGGCTTATTGGACTGATGAAGGTTTTGTGGCAAAGGCAGACTGAGTAGCCCT
AGCCAGAGAAAGCAGCCGCC

Downstream 100 bases:

>100_bases
CGTTCTCGCAACAGCTATTTCGGACAAAAGAAAAGGCGGCGCTTTCGCGCCGCCTGGAAACCCGCGAGCATGGGAGGAGC
TTGCTCAAGCGGGTCGACGT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSEIRLYVTTTEIKAGEILDLMSDYFGEEDVAIATTEVDEKRDIWEASVYLMAEQEEEFRERVSTLLAPAFPGLVIEKEI
IPDVDWIAKSLEGLKPVRAGRFIVHGAHDRDKVQPHDLAIEIEAGQAFGTGHHGTTAGCLEMIEDVLRARKVRNALDLGT
GSGVLAIAVRKMRPIPVLATDIDPIAVKVAKENVRLNGIVSGMALETAPGFHSDAFRKHGPFDLIIANILARPLIKMAPQ
LVTHLAPGGTVILSGILASQRWKVLSAYNGAKLSHIRTIWRNDWVTLHLRKD

Sequences:

>Translated_292_residues
MSEIRLYVTTTEIKAGEILDLMSDYFGEEDVAIATTEVDEKRDIWEASVYLMAEQEEEFRERVSTLLAPAFPGLVIEKEI
IPDVDWIAKSLEGLKPVRAGRFIVHGAHDRDKVQPHDLAIEIEAGQAFGTGHHGTTAGCLEMIEDVLRARKVRNALDLGT
GSGVLAIAVRKMRPIPVLATDIDPIAVKVAKENVRLNGIVSGMALETAPGFHSDAFRKHGPFDLIIANILARPLIKMAPQ
LVTHLAPGGTVILSGILASQRWKVLSAYNGAKLSHIRTIWRNDWVTLHLRKD
>Mature_291_residues
SEIRLYVTTTEIKAGEILDLMSDYFGEEDVAIATTEVDEKRDIWEASVYLMAEQEEEFRERVSTLLAPAFPGLVIEKEII
PDVDWIAKSLEGLKPVRAGRFIVHGAHDRDKVQPHDLAIEIEAGQAFGTGHHGTTAGCLEMIEDVLRARKVRNALDLGTG
SGVLAIAVRKMRPIPVLATDIDPIAVKVAKENVRLNGIVSGMALETAPGFHSDAFRKHGPFDLIIANILARPLIKMAPQL
VTHLAPGGTVILSGILASQRWKVLSAYNGAKLSHIRTIWRNDWVTLHLRKD

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=196, Percent_Identity=33.1632653061224, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_AGRT5 (Q8UDP9)

Other databases:

- EMBL:   AE007869
- PIR:   AI2830
- PIR:   E97608
- RefSeq:   NP_355037.1
- ProteinModelPortal:   Q8UDP9
- STRING:   Q8UDP9
- GeneID:   1134110
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2072
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   GHHGTTL
- PhylomeDB:   Q8UDP9
- ProtClustDB:   PRK00517
- BioCyc:   ATUM176299-1:ATU2072-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 32188; Mature: 32056

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIRLYVTTTEIKAGEILDLMSDYFGEEDVAIATTEVDEKRDIWEASVYLMAEQEEEFR
CCCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHEEEEEEECCHHHHH
ERVSTLLAPAFPGLVIEKEIIPDVDWIAKSLEGLKPVRAGRFIVHGAHDRDKVQPHDLAI
HHHHHHHHCCCCCEEEEHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEE
EIEAGQAFGTGHHGTTAGCLEMIEDVLRARKVRNALDLGTGSGVLAIAVRKMRPIPVLAT
EEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCCEEEE
DIDPIAVKVAKENVRLNGIVSGMALETAPGFHSDAFRKHGPFDLIIANILARPLIKMAPQ
CCCCEEEEEECCCEEEEEEEECEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
LVTHLAPGGTVILSGILASQRWKVLSAYNGAKLSHIRTIWRNDWVTLHLRKD
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure 
SEIRLYVTTTEIKAGEILDLMSDYFGEEDVAIATTEVDEKRDIWEASVYLMAEQEEEFR
CCEEEEEEEECCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHEEEEEEECCHHHHH
ERVSTLLAPAFPGLVIEKEIIPDVDWIAKSLEGLKPVRAGRFIVHGAHDRDKVQPHDLAI
HHHHHHHHCCCCCEEEEHHHCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEE
EIEAGQAFGTGHHGTTAGCLEMIEDVLRARKVRNALDLGTGSGVLAIAVRKMRPIPVLAT
EEECCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHCCCCCEEEE
DIDPIAVKVAKENVRLNGIVSGMALETAPGFHSDAFRKHGPFDLIIANILARPLIKMAPQ
CCCCEEEEEECCCEEEEEEEECEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
LVTHLAPGGTVILSGILASQRWKVLSAYNGAKLSHIRTIWRNDWVTLHLRKD
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194