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The map label for this gene is tktB [C]

Identifier: 15889197

GI number: 15889197

Start: 1878306

End: 1879115

Strand: Direct

Name: tktB [C]

Synonym: Atu1901

Alternate gene names: 15889197

Gene position: 1878306-1879115 (Clockwise)

Preceding gene: 15889192

Following gene: 159184971

Centisome position: 66.1

GC content: 60.62

Gene sequence:

>810_bases
ATGCAGTCCCAGGAGCTAGAGCGCATTGCGCGCCAGATTCGCCTTCGCGACGTACAGGCTGTTTTTGAAGCGGGTGCGGG
CCATGTCGGCGGCGAAATGTCGGCCATCGACATCATGACGGCCCTTTATTTCCGCGTCCTGCGCATCTGGCCGAATGATC
CGAAGAACCCTGCCCGCGACCGTTTCGTACTTTCCAAGGGCCACACAGCCTGCGCGCTTTACGTGACGCTGGCCAAGCGC
GGTTTCATTCCGGAAGAGGAAATCTCGACCTTCCTGCAGCCGAATTCGCGCCTCAACGGCCATCCCAACTGCAACAAGGT
GCCGGGCGTCGAAACCAATACCGGCCCGCTCGGCCACGGGCTTCCCGTCGCCGTCGGCATGGCCACGGCGGCCAAGCTGT
CCGGCGAGGATTACCACACCTACGTGATGACCGGCGACGGCGAGATGCAGGAAGGCTCCAACTGGGAAGCCATCATGTCG
GCGGCGCAATTCAAGCTGAACAATCTGACGCTGGTCATCGACCATAACCGTTTCCAGCAGGGCGCCGCCATTGCCGACAC
CAACGATGTCGCGCCGCTTCGCCCCAAGCTTGAGGCTTTCGGCTGGGAAGTGACTGAAATCAACGGCAACGCCATGGCGG
AAGTCGTTCCGGCGCTGGAGCATCGCGGCAACCGCCCGCATTGCATCGTCGCCCACACCAACAAGGGTCACGGCATTTCC
TTCATGCAGGACCGCGTCGACTGGCATCACAAGGTTCCGAGCAAGGAACAATACGAGATTGCCGTCAAAGAACTTTCGGA
GGCATTGTAA

Upstream 100 bases:

>100_bases
AGACAGAACAATTCACGATTCCGGCTTGACAGAAACGCCATCTCTGCAATTATATAAATAGCTGTATAAATATTCACACG
CATGTTTTGAAGAGGATTCC

Downstream 100 bases:

>100_bases
TGAACGCGCCCGTAACCGCCGCCAAACTGTATGATTGCCGCGACGCCTTCGCCGAAACGCTGGAAGCGCTGGCCGCCGCC
AATGACAAGGTCGTCGCCGT

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MQSQELERIARQIRLRDVQAVFEAGAGHVGGEMSAIDIMTALYFRVLRIWPNDPKNPARDRFVLSKGHTACALYVTLAKR
GFIPEEEISTFLQPNSRLNGHPNCNKVPGVETNTGPLGHGLPVAVGMATAAKLSGEDYHTYVMTGDGEMQEGSNWEAIMS
AAQFKLNNLTLVIDHNRFQQGAAIADTNDVAPLRPKLEAFGWEVTEINGNAMAEVVPALEHRGNRPHCIVAHTNKGHGIS
FMQDRVDWHHKVPSKEQYEIAVKELSEAL

Sequences:

>Translated_269_residues
MQSQELERIARQIRLRDVQAVFEAGAGHVGGEMSAIDIMTALYFRVLRIWPNDPKNPARDRFVLSKGHTACALYVTLAKR
GFIPEEEISTFLQPNSRLNGHPNCNKVPGVETNTGPLGHGLPVAVGMATAAKLSGEDYHTYVMTGDGEMQEGSNWEAIMS
AAQFKLNNLTLVIDHNRFQQGAAIADTNDVAPLRPKLEAFGWEVTEINGNAMAEVVPALEHRGNRPHCIVAHTNKGHGIS
FMQDRVDWHHKVPSKEQYEIAVKELSEAL
>Mature_269_residues
MQSQELERIARQIRLRDVQAVFEAGAGHVGGEMSAIDIMTALYFRVLRIWPNDPKNPARDRFVLSKGHTACALYVTLAKR
GFIPEEEISTFLQPNSRLNGHPNCNKVPGVETNTGPLGHGLPVAVGMATAAKLSGEDYHTYVMTGDGEMQEGSNWEAIMS
AAQFKLNNLTLVIDHNRFQQGAAIADTNDVAPLRPKLEAFGWEVTEINGNAMAEVVPALEHRGNRPHCIVAHTNKGHGIS
FMQDRVDWHHKVPSKEQYEIAVKELSEAL

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=270, Percent_Identity=38.1481481481481, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI4507521, Length=270, Percent_Identity=38.1481481481481, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI133778974, Length=264, Percent_Identity=34.0909090909091, Blast_Score=154, Evalue=8e-38,
Organism=Homo sapiens, GI225637459, Length=264, Percent_Identity=28.4090909090909, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI225637461, Length=264, Percent_Identity=27.6515151515151, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI225637463, Length=229, Percent_Identity=28.82096069869, Blast_Score=105, Evalue=4e-23,
Organism=Escherichia coli, GI1788808, Length=278, Percent_Identity=33.0935251798561, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI48994911, Length=249, Percent_Identity=35.3413654618474, Blast_Score=124, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17539652, Length=251, Percent_Identity=33.8645418326693, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6325331, Length=256, Percent_Identity=35.9375, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319593, Length=254, Percent_Identity=33.4645669291339, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI45551847, Length=266, Percent_Identity=34.9624060150376, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI45550715, Length=266, Percent_Identity=34.9624060150376, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24666278, Length=267, Percent_Identity=33.7078651685393, Blast_Score=151, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24645119, Length=231, Percent_Identity=36.3636363636364, Blast_Score=149, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 29712; Mature: 29712

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSQELERIARQIRLRDVQAVFEAGAGHVGGEMSAIDIMTALYFRVLRIWPNDPKNPARD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RFVLSKGHTACALYVTLAKRGFIPEEEISTFLQPNSRLNGHPNCNKVPGVETNTGPLGHG
CEEEECCCCEEEHHEEHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LPVAVGMATAAKLSGEDYHTYVMTGDGEMQEGSNWEAIMSAAQFKLNNLTLVIDHNRFQQ
CHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHEEECCEEEEEECCCCCC
GAAIADTNDVAPLRPKLEAFGWEVTEINGNAMAEVVPALEHRGNRPHCIVAHTNKGHGIS
CCEECCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
FMQDRVDWHHKVPSKEQYEIAVKELSEAL
HHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQSQELERIARQIRLRDVQAVFEAGAGHVGGEMSAIDIMTALYFRVLRIWPNDPKNPARD
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
RFVLSKGHTACALYVTLAKRGFIPEEEISTFLQPNSRLNGHPNCNKVPGVETNTGPLGHG
CEEEECCCCEEEHHEEHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LPVAVGMATAAKLSGEDYHTYVMTGDGEMQEGSNWEAIMSAAQFKLNNLTLVIDHNRFQQ
CHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHEEECCEEEEEECCCCCC
GAAIADTNDVAPLRPKLEAFGWEVTEINGNAMAEVVPALEHRGNRPHCIVAHTNKGHGIS
CCEECCCCCCCCCCCHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHH
FMQDRVDWHHKVPSKEQYEIAVKELSEAL
HHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]