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The map label for this gene is fabF [C]

Identifier: 15888910

GI number: 15888910

Start: 1579602

End: 1580798

Strand: Reverse

Name: fabF [C]

Synonym: Atu1597

Alternate gene names: 15888910

Gene position: 1580798-1579602 (Counterclockwise)

Preceding gene: 15888911

Following gene: 15888909

Centisome position: 55.63

GC content: 62.32

Gene sequence:

>1197_bases
ATGAAATCTGACAATGATGTGGTGATAACAGGGGTCGGCATCGTGACCTGTCACGGCGTTGGCAGCCAGGCGCATGTGGC
GCTTCTTTCTGGAGCCGCCGTGCCGGAGCCGGTTGTCGAGACCGAAAAATTCAAACCCTACCCGGTCCATCCCATGCCGG
AAATCGACTGGTCGGCACAGATTGCCAAGCGCGGGGACCAGCGCCAGATGGAAAACTGGCAGCGTCTCGGCGTTTTCGCC
GCCGGTCTTGCGCTTGATGATGCCGGGCTGAAGGAAAATACCGAAGCCTGCGCCACCATGGACATGATCGTTGCCGCCGG
CGGCGGCGAGCGCGACATCAATGTCGACACGCTGATCGTCGATGAGGCGCTGAAGCGCAACGACCGTGAAAAGCTGCTGA
ACGAGAAGCTGACGACGGAACTGCGCCCGACGCTGTTTCTCGCCCAGCTTTCCAACCTGATGGCCGGCAATATCTCCATC
GTGCACAAGGTCACCGGTTCGTCGCGCACCTTCATGGGCGAAGAAGCGGCCGGCATTTCCGCCGTCGAAACCGCGTTCCA
TCGCATTCGTTCCGGTGAATCGAGCCACGCCCTTGTCGGCGGCGCCTTCTCGGCTGAACGTCCCGACATGATCCTGCTGT
TCGAAGCCATCGGCGCACATGCACAGGGCGGCTGGCAGCCGCTTTGGTCGCGTGGCGACCAGGACGGCGGCGGCATGATT
TCCGGTTCGCTCGGTGCATTCCTCGTGCTGGAATCGCGCAAGCATGCCAGCGAGCGTGGCGCGCGCATCTATGCCCGCAT
CGACGCCATCGAGGGCGACCGTGGCAGCCGCGATGACGGCAAGATGGAAAAGCGCATGGAGCGCCTGCTTGCGCCTGCAA
AGGACAGCGCTGCGACCGTCGTGTTTTCCGGCGCGAGCGGTTATGACGAGGTAACGGTTCGCGAGAAGGATATTCTCGAA
AAGGTGCTGCCAAATTCGGTCATTCGTGGTTTCGGCGGTGTCACCGGTCATGGACTTGAGGCGCAGTTTCCGCTCGGGCT
CGCTCTGGCGGCGTTGACGCTTGAAAGCGGCGCGAAGGTTCCTACCTTCGATGCGGCTGCGGAAAAGCCGATGGGCGAAG
CGGCCACAGAGGCTGTCGTCACCACCGTCGGGCATGTGCGCGGCGAAGGTGTCGCCGTCCTGTCCCGTGACGTGTGA

Upstream 100 bases:

>100_bases
CATCGCGCGCTTTATTCCGCAACGCATGAAGTGGTTGTTCGCAACCGCTGTGGATAGCCGTGACCGTTTCGGCGGGGCCG
GCTGCAAAGGATGACAGACG

Downstream 100 bases:

>100_bases
GGAGAAGAGACCATGACCAATTTTAAGGATCATCTCGGTCGCCCGATCGTTGCCGTGACCGGCATGGGCATCATCACCTC
GCTCGGTCAGGGACTTGCCG

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: [acyl carrier protein]; acetoacetyl-ACP; CO2; [acyl carrier protein]; beta-ketoacyl-ACP [C]

Alternate protein names: Beta-Ketoacyl Synthase; 3-Oxoacyl-(Acyl-Carrier-Protein) Synthase II; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase II Protein; 3-Oxoacyl-(Acyl-Acp) Synthase II Protein; 3-Oxoacyl-[Acyl-Carrier-Protein] Synthase II

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MKSDNDVVITGVGIVTCHGVGSQAHVALLSGAAVPEPVVETEKFKPYPVHPMPEIDWSAQIAKRGDQRQMENWQRLGVFA
AGLALDDAGLKENTEACATMDMIVAAGGGERDINVDTLIVDEALKRNDREKLLNEKLTTELRPTLFLAQLSNLMAGNISI
VHKVTGSSRTFMGEEAAGISAVETAFHRIRSGESSHALVGGAFSAERPDMILLFEAIGAHAQGGWQPLWSRGDQDGGGMI
SGSLGAFLVLESRKHASERGARIYARIDAIEGDRGSRDDGKMEKRMERLLAPAKDSAATVVFSGASGYDEVTVREKDILE
KVLPNSVIRGFGGVTGHGLEAQFPLGLALAALTLESGAKVPTFDAAAEKPMGEAATEAVVTTVGHVRGEGVAVLSRDV

Sequences:

>Translated_398_residues
MKSDNDVVITGVGIVTCHGVGSQAHVALLSGAAVPEPVVETEKFKPYPVHPMPEIDWSAQIAKRGDQRQMENWQRLGVFA
AGLALDDAGLKENTEACATMDMIVAAGGGERDINVDTLIVDEALKRNDREKLLNEKLTTELRPTLFLAQLSNLMAGNISI
VHKVTGSSRTFMGEEAAGISAVETAFHRIRSGESSHALVGGAFSAERPDMILLFEAIGAHAQGGWQPLWSRGDQDGGGMI
SGSLGAFLVLESRKHASERGARIYARIDAIEGDRGSRDDGKMEKRMERLLAPAKDSAATVVFSGASGYDEVTVREKDILE
KVLPNSVIRGFGGVTGHGLEAQFPLGLALAALTLESGAKVPTFDAAAEKPMGEAATEAVVTTVGHVRGEGVAVLSRDV
>Mature_398_residues
MKSDNDVVITGVGIVTCHGVGSQAHVALLSGAAVPEPVVETEKFKPYPVHPMPEIDWSAQIAKRGDQRQMENWQRLGVFA
AGLALDDAGLKENTEACATMDMIVAAGGGERDINVDTLIVDEALKRNDREKLLNEKLTTELRPTLFLAQLSNLMAGNISI
VHKVTGSSRTFMGEEAAGISAVETAFHRIRSGESSHALVGGAFSAERPDMILLFEAIGAHAQGGWQPLWSRGDQDGGGMI
SGSLGAFLVLESRKHASERGARIYARIDAIEGDRGSRDDGKMEKRMERLLAPAKDSAATVVFSGASGYDEVTVREKDILE
KVLPNSVIRGFGGVTGHGLEAQFPLGLALAALTLESGAKVPTFDAAAEKPMGEAATEAVVTTVGHVRGEGVAVLSRDV

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.41 [C]

Molecular weight: Translated: 42162; Mature: 42162

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSDNDVVITGVGIVTCHGVGSQAHVALLSGAAVPEPVVETEKFKPYPVHPMPEIDWSAQ
CCCCCCEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
IAKRGDQRQMENWQRLGVFAAGLALDDAGLKENTEACATMDMIVAAGGGERDINVDTLIV
HHHCCCHHHHHHHHHHHHHHHCEEECCCCCCCCCHHHHHHEEEEECCCCCCCCCCHHEEH
DEALKRNDREKLLNEKLTTELRPTLFLAQLSNLMAGNISIVHKVTGSSRTFMGEEAAGIS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCCHH
AVETAFHRIRSGESSHALVGGAFSAERPDMILLFEAIGAHAQGGWQPLWSRGDQDGGGMI
HHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEHHCCCCCCCCCHHHCCCCCCCCCEE
SGSLGAFLVLESRKHASERGARIYARIDAIEGDRGSRDDGKMEKRMERLLAPAKDSAATV
ECCCCEEEEEECHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
VFSGASGYDEVTVREKDILEKVLPNSVIRGFGGVTGHGLEAQFPLGLALAALTLESGAKV
EEECCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PTFDAAAEKPMGEAATEAVVTTVGHVRGEGVAVLSRDV
CCCCHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MKSDNDVVITGVGIVTCHGVGSQAHVALLSGAAVPEPVVETEKFKPYPVHPMPEIDWSAQ
CCCCCCEEEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
IAKRGDQRQMENWQRLGVFAAGLALDDAGLKENTEACATMDMIVAAGGGERDINVDTLIV
HHHCCCHHHHHHHHHHHHHHHCEEECCCCCCCCCHHHHHHEEEEECCCCCCCCCCHHEEH
DEALKRNDREKLLNEKLTTELRPTLFLAQLSNLMAGNISIVHKVTGSSRTFMGEEAAGIS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEECCCCCCCHH
AVETAFHRIRSGESSHALVGGAFSAERPDMILLFEAIGAHAQGGWQPLWSRGDQDGGGMI
HHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEEHHCCCCCCCCCHHHCCCCCCCCCEE
SGSLGAFLVLESRKHASERGARIYARIDAIEGDRGSRDDGKMEKRMERLLAPAKDSAATV
ECCCCEEEEEECHHHHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
VFSGASGYDEVTVREKDILEKVLPNSVIRGFGGVTGHGLEAQFPLGLALAALTLESGAKV
EEECCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
PTFDAAAEKPMGEAATEAVVTTVGHVRGEGVAVLSRDV
CCCCHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: None [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]

Substrates: acetyl-ACP; malonyl-ACP; acyl-ACP [C]

Specific reaction: acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 [C]

General reaction: Acyl group transfer [C]

Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl-ACP-decarboxylation, Cerulenin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA