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The map label for this gene is fabZ [H]

Identifier: 15888911

GI number: 15888911

Start: 1581007

End: 1581486

Strand: Reverse

Name: fabZ [H]

Synonym: Atu1599

Alternate gene names: 15888911

Gene position: 1581486-1581007 (Counterclockwise)

Preceding gene: 159184832

Following gene: 15888910

Centisome position: 55.66

GC content: 59.58

Gene sequence:

>480_bases
ATGCTGCTTGAATATTTTCAGATGATCGACAAGGTCGAATCCGTGGATATGGCGACGCGCACGCTGAAGGCGCAGTCGGT
CGTTCCGGACCATAGCCCGGTTTTCGAAGGCCACTTTCCCGGCATGCCGCTGGTTCCGGGTGTACTCCTGATCGAGACCA
TGGCGCAGGCTTCCGGCATGATGGTTCTGGCATTTTCCGATTTTGCGTCCATGCCGTTCCTGATGTCGGTCGATGGCGCC
AAGATGCGCACCTTCGTGGAGCCGGGCGCCGTTCTCGACATCGAGGCGGTGCTGGAGCATGACGGTTCGGGCTTTGCCGT
TACCAAGGCGAAGATCACCTCTGCCGGCAAGAAGGTCTGCGACGCGCAACTGAAACTGCGCACCATGCCGTTCAGCGAAA
TTCCGCTCGGTCCCATCGTCAAGAAGCGGGCCGAGGAAGTTGGCCTGATGGCGGCCATTGCCGCGGACGCGCAGAAATAA

Upstream 100 bases:

>100_bases
CCAAGGGCTGATCTGACAATGCCCGCATCGAGCGGGCATTTCTTTTTCCGGACCCGGCCCTGTTGGGCGGGTCGCAACCG
ACCAGAGACAGGCCGGACCG

Downstream 100 bases:

>100_bases
GCGCTTCCGCCCGTTTCAAAAGAGGGCGTTTTTTCCGTCGGCCCGGTTTCGATGCATGAAAATCGTGGGCTCGCGACGGC
GGATCGGGCCTTCGCCATTG

Product: (3R)-hydroxymyristoyl-(acyl carrier protein)- dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MLLEYFQMIDKVESVDMATRTLKAQSVVPDHSPVFEGHFPGMPLVPGVLLIETMAQASGMMVLAFSDFASMPFLMSVDGA
KMRTFVEPGAVLDIEAVLEHDGSGFAVTKAKITSAGKKVCDAQLKLRTMPFSEIPLGPIVKKRAEEVGLMAAIAADAQK

Sequences:

>Translated_159_residues
MLLEYFQMIDKVESVDMATRTLKAQSVVPDHSPVFEGHFPGMPLVPGVLLIETMAQASGMMVLAFSDFASMPFLMSVDGA
KMRTFVEPGAVLDIEAVLEHDGSGFAVTKAKITSAGKKVCDAQLKLRTMPFSEIPLGPIVKKRAEEVGLMAAIAADAQK
>Mature_159_residues
MLLEYFQMIDKVESVDMATRTLKAQSVVPDHSPVFEGHFPGMPLVPGVLLIETMAQASGMMVLAFSDFASMPFLMSVDGA
KMRTFVEPGAVLDIEAVLEHDGSGFAVTKAKITSAGKKVCDAQLKLRTMPFSEIPLGPIVKKRAEEVGLMAAIAADAQK

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=124, Percent_Identity=33.8709677419355, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 17087; Mature: 17087

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
7.5 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
7.5 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLEYFQMIDKVESVDMATRTLKAQSVVPDHSPVFEGHFPGMPLVPGVLLIETMAQASGM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCE
MVLAFSDFASMPFLMSVDGAKMRTFVEPGAVLDIEAVLEHDGSGFAVTKAKITSAGKKVC
EEEEECCCCCCCEEEECCCCHHEEEECCCCEEEHHHHHHCCCCCEEEEHHHHHHHHHHHH
DAQLKLRTMPFSEIPLGPIVKKRAEEVGLMAAIAADAQK
HHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLLEYFQMIDKVESVDMATRTLKAQSVVPDHSPVFEGHFPGMPLVPGVLLIETMAQASGM
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCE
MVLAFSDFASMPFLMSVDGAKMRTFVEPGAVLDIEAVLEHDGSGFAVTKAKITSAGKKVC
EEEEECCCCCCCEEEECCCCHHEEEECCCCEEEHHHHHHCCCCCEEEEHHHHHHHHHHHH
DAQLKLRTMPFSEIPLGPIVKKRAEEVGLMAAIAADAQK
HHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA