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The map label for this gene is nah [H]

Identifier: 15888892

GI number: 15888892

Start: 1559628

End: 1560809

Strand: Direct

Name: nah [H]

Synonym: Atu1574

Alternate gene names: 15888892

Gene position: 1559628-1560809 (Clockwise)

Preceding gene: 159184822

Following gene: 159184823

Centisome position: 54.89

GC content: 64.64

Gene sequence:

>1182_bases
ATGCCCATAAAATCCGTAGCCATTATCGGTGCCGGCATTGCCGGTCTCACCGCTGCCCTTGCTTTTGCCCGGCACGGTAT
AGACTGCGACATCATCGAACAGACCGGCGAGCTGGCGGAAGTCGGCGCCGGCCTGCAGCTTTCCCCCAATGCCGCCCGCA
TTCTGGCCACGCTCGGCGTCCTGCCTGACATCGAGGCGCGCTGGACCGAACCGGTCAGCGTCGACCTCGCCTCCGGAAAA
TCGCTGACCACGCTGCTCTCTCTGCCAATGGGCGCGGTCGCCCGCAGCCGCTGGGGCGCACCCTATGGGGTGCTACACCG
CTCGACGCTGCAAAGCGCGCTTCTCCAGGCGGTGACACGCAATCCCCTCTGCCGGCTGCATCTCGGCAAACGTATCGAAA
ACGCCACCGCCGATGTCATTGCCGCAACGACGTTTCGTGATCACGATCTGATCGTCGGCGCCGACGGCGTCTGGTCGGCG
GCCCGTTTCTCCGTGCCGGCGGCACCCACCGCCACCTTCTCGGGCAATGTCGCCTGGCGCTTCACCGTCGCCGCAGAAGA
GGTGCCGTCCGCCTTCAACAAAACCACCGTCACGGCCTATCTCGGCTCCCGTGGCCATATCGTTGCCTATCCGCTGAAGG
AAGTCGGTGGCTTCAACATCGTCGCCATCGCGCTCGGCGCCGATCCCGGTGCGACGTGGCGGGCGGAATCAAGCGGGCGG
CAGAAAGCCCTTTTGCTGGAGCAATTTCGCGACTTCAGCCCTGACATCGTCCGATTGCTCGATTCATCTGAAAATCCGAC
CTTCTGGCCGCTCTACCAGGCCGGCCCCGGCCGCTGGCACAATGGCCGCGACACGGTGCTGATCGGCGATGCCGCACACG
CCATGATGCCCTTCGCCGCCCAGGGTGCGGCCATGGCAATAGAGGATGCGTTCGAACTTGCGGGAACGATGGCAGGTAGT
AACGGCGAAAAGCCCCTGCCCGTGCCGCAGGCCCTCGCCGCCTTCGAGGCGCTGCGCCTGCCGCGCATAGAAAAGGCCCG
CAAGCGGGCCTCTCTCAATCGTTTTGCCTATCATGCCAGAGGCCCGGTGCGCATCGCACGGGACCTGGTATTTTCCACCC
GTCCCCCGGAAGCTTTCCTGAAGGACTTCGACTGGCTCTACGGCTATCACGCCAGGGGCTGA

Upstream 100 bases:

>100_bases
GTTACAACCCGTCGCTGAAGGCCGAGCAGACCAATCCTCCGGGCTGTGTTTTCCATGTGAAGGCCGCCTGACCTTCCACT
CTTCCTGATCGGGGCGCATC

Downstream 100 bases:

>100_bases
GGGCTGGGCTCAGACCCCGGCCGCGGCTGAAAAACCGGCCTCGAGGTCTTTCTTGAGATCGGCGACATCCTCGAGCCCGA
TCTGCAGACGGATGACCGGT

Product: salicylate hydroxylase

Products: NA

Alternate protein names: Constitutive 3-hydroxybenzoate 6-hydroxylase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPIKSVAIIGAGIAGLTAALAFARHGIDCDIIEQTGELAEVGAGLQLSPNAARILATLGVLPDIEARWTEPVSVDLASGK
SLTTLLSLPMGAVARSRWGAPYGVLHRSTLQSALLQAVTRNPLCRLHLGKRIENATADVIAATTFRDHDLIVGADGVWSA
ARFSVPAAPTATFSGNVAWRFTVAAEEVPSAFNKTTVTAYLGSRGHIVAYPLKEVGGFNIVAIALGADPGATWRAESSGR
QKALLLEQFRDFSPDIVRLLDSSENPTFWPLYQAGPGRWHNGRDTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGTMAGS
NGEKPLPVPQALAAFEALRLPRIEKARKRASLNRFAYHARGPVRIARDLVFSTRPPEAFLKDFDWLYGYHARG

Sequences:

>Translated_393_residues
MPIKSVAIIGAGIAGLTAALAFARHGIDCDIIEQTGELAEVGAGLQLSPNAARILATLGVLPDIEARWTEPVSVDLASGK
SLTTLLSLPMGAVARSRWGAPYGVLHRSTLQSALLQAVTRNPLCRLHLGKRIENATADVIAATTFRDHDLIVGADGVWSA
ARFSVPAAPTATFSGNVAWRFTVAAEEVPSAFNKTTVTAYLGSRGHIVAYPLKEVGGFNIVAIALGADPGATWRAESSGR
QKALLLEQFRDFSPDIVRLLDSSENPTFWPLYQAGPGRWHNGRDTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGTMAGS
NGEKPLPVPQALAAFEALRLPRIEKARKRASLNRFAYHARGPVRIARDLVFSTRPPEAFLKDFDWLYGYHARG
>Mature_392_residues
PIKSVAIIGAGIAGLTAALAFARHGIDCDIIEQTGELAEVGAGLQLSPNAARILATLGVLPDIEARWTEPVSVDLASGKS
LTTLLSLPMGAVARSRWGAPYGVLHRSTLQSALLQAVTRNPLCRLHLGKRIENATADVIAATTFRDHDLIVGADGVWSAA
RFSVPAAPTATFSGNVAWRFTVAAEEVPSAFNKTTVTAYLGSRGHIVAYPLKEVGGFNIVAIALGADPGATWRAESSGRQ
KALLLEQFRDFSPDIVRLLDSSENPTFWPLYQAGPGRWHNGRDTVLIGDAAHAMMPFAAQGAAMAIEDAFELAGTMAGSN
GEKPLPVPQALAAFEALRLPRIEKARKRASLNRFAYHARGPVRIARDLVFSTRPPEAFLKDFDWLYGYHARG

Specific function: Catalyzes the NAD- or NADP-dependent conversion of 3- hydroxybenzoate to gentisate. The affinity of the enzyme toward NAD is twice as high as for NADP. The enzyme shows higher specific activities against the intermediates in the degradation of 2,5- xyleno

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxybenzoate 6-hydroxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: =1.14.13.24 [H]

Molecular weight: Translated: 42009; Mature: 41878

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKSVAIIGAGIAGLTAALAFARHGIDCDIIEQTGELAEVGAGLQLSPNAARILATLGV
CCCCEEEEECCCHHHHHHHHHHHHCCCCEEHHHHCCCHHHHCCCCEECCCHHHHHHHHCC
LPDIEARWTEPVSVDLASGKSLTTLLSLPMGAVARSRWGAPYGVLHRSTLQSALLQAVTR
CCCCCCCCCCCCEEEECCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
NPLCRLHLGKRIENATADVIAATTFRDHDLIVGADGVWSAARFSVPAAPTATFSGNVAWR
CCEEEEHHHHHHCCCCHHEEEEEEECCCCEEEECCCCCCHHEECCCCCCCCEECCCEEEE
FTVAAEEVPSAFNKTTVTAYLGSRGHIVAYPLKEVGGFNIVAIALGADPGATWRAESSGR
EEEEHHHHHHHHCCCEEEEEECCCCCEEEEEHHHCCCCEEEEEEEECCCCCCEECCCCCC
QKALLLEQFRDFSPDIVRLLDSSENPTFWPLYQAGPGRWHNGRDTVLIGDAAHAMMPFAA
HHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEECCHHHHHCCHHC
QGAAMAIEDAFELAGTMAGSNGEKPLPVPQALAAFEALRLPRIEKARKRASLNRFAYHAR
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHECCC
GPVRIARDLVFSTRPPEAFLKDFDWLYGYHARG
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PIKSVAIIGAGIAGLTAALAFARHGIDCDIIEQTGELAEVGAGLQLSPNAARILATLGV
CCCEEEEECCCHHHHHHHHHHHHCCCCEEHHHHCCCHHHHCCCCEECCCHHHHHHHHCC
LPDIEARWTEPVSVDLASGKSLTTLLSLPMGAVARSRWGAPYGVLHRSTLQSALLQAVTR
CCCCCCCCCCCCEEEECCCCCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
NPLCRLHLGKRIENATADVIAATTFRDHDLIVGADGVWSAARFSVPAAPTATFSGNVAWR
CCEEEEHHHHHHCCCCHHEEEEEEECCCCEEEECCCCCCHHEECCCCCCCCEECCCEEEE
FTVAAEEVPSAFNKTTVTAYLGSRGHIVAYPLKEVGGFNIVAIALGADPGATWRAESSGR
EEEEHHHHHHHHCCCEEEEEECCCCCEEEEEHHHCCCCEEEEEEEECCCCCCEECCCCCC
QKALLLEQFRDFSPDIVRLLDSSENPTFWPLYQAGPGRWHNGRDTVLIGDAAHAMMPFAA
HHHHHHHHHHCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEECCHHHHHCCHHC
QGAAMAIEDAFELAGTMAGSNGEKPLPVPQALAAFEALRLPRIEKARKRASLNRFAYHAR
CCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHECCC
GPVRIARDLVFSTRPPEAFLKDFDWLYGYHARG
CHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12909360 [H]