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The map label for this gene is hvsT [C]

Identifier: 15888861

GI number: 15888861

Start: 1528866

End: 1530479

Strand: Direct

Name: hvsT [C]

Synonym: Atu1539

Alternate gene names: 15888861

Gene position: 1528866-1530479 (Clockwise)

Preceding gene: 159184804

Following gene: 15888862

Centisome position: 53.8

GC content: 61.59

Gene sequence:

>1614_bases
ATGGGTAACAACGGGCGGGATATTCTCGCAGGGCTTTCCGTCGCCGGGCTGATGTTACCGGAGGCGATCGCTTATTCCGG
CATCGCCGGCGTTCCGCCCCAGCATGCATTATATGCGGCAATGGCAGGTTGTCTTGTTTATGCCCTTCTTGGCCAGAGCC
GTTTCGCCATCATCTCGCCAACCTCATCATCCGCCGCGATCCTTGCAGCCATGCTGGCCGCGCTCGTGCCGCAGCCCGGA
CAGAAGATGCTGCTGGTCGCCGTCGCGGTGTTTCTTGTCGGGCTGTTTTTCCTTGCCGCCGGCACATTGCGGCTGGGCGC
CCTGTCGAGCATCATTTCGAGGCCCGTGCTGCGCGGCTTTGCATTCGGACTGGCGATCCTCATTTCGCTCAAACAGTTTC
CCGCGATCTTCGGCATGCCGCAAGCGGGAGCCGGCACATTCGAGGCGATCTTGCAGATATTGACCAATCCCGGCCAGTGG
AACGGGTTCAGCCTGTCGATCGGCATCGCCGCCCTTATCCTTCTGCTTTTCGCAAGACGTTATCCCCAGATTCCCGGAAG
CCTCATCATCATAGCGCTGGCGATCCCCATCTCCGTCATGTTCGATTTGCAGCAACGCGGTGTCGATGTCGTCGGCCCAA
TCGATCTGTCCGGCATATGGGGAAGTGTCACCACGCTCTCGCTCGATGAACTGGCGCATGTGGCGCGTTTCGCCCCGCCT
CTGGTGCTGATCCTGTTTGCCGAATCCTGGGGAACGATACGGGGCCTGTCGCTACGGCACGGGGAAGACGTGGATGCCAA
TCGTGAACTGAAAACGCTTGGTATTGCCAATGTCGCAAGCGCCGCATTACAGGGAATGCCCGTCGGGGCCGGGTTTTCCG
CGGGTGCTGCAAGCGAAGCGGCCAATCCGCGCACGAGAATGGCCTCGGCCATCGCCGCGATCGGGCTTGCCGGCTTCACC
TTTGCCGCGGCCGACTGGTTTGCCTATATTCCGCATGCCGCGCTTTCCGCCATCATCATCGTGGCGCTGCTTCACGCGCT
GGATCCCTCTCCGTTTTTGAGGCTGTGGCGGCTGCGACAGGACCTCGTGCTTGCCCTGGCGGCAACCGCCGGCGTGCTTT
TCCTTGGCGTCCTCAACGGAATGCTGGCAGCAATCGTGCTGTCTTTCGCCGTATTCCTGCAAAGACTTTCCTCCCCGCGC
ATCGTGATGCTCGGCCGCCTCGGCGCGAGCCACGACTTCGTGGATGTGAAGCGGCATCCGGATGCCGCGGAGCCGGCCGG
CATGCTCGTCCTGCGCCCGGCGCAACCGCTTTTCTTCGGAAATGCCGAGCCGACATTCGCGGAAATCACCCGCCGCATAC
TCGCGAGCCCTGACATCAACGCCGTCATCATCAGCCTCGAGGAGACATTTGAACTCGATACGACAGCCCTTGAGGCGCTG
CTGGAATTCGACGCCAGCCTGCGCGGGCGCAACATCGGAATTCGCTACGCCCCAATGCACGATGCGGTGCGCGACGTTGT
CGCCGCCGGTGGCGGAGACGATCTTTTGCGTCGGGCAAACTACAGCGTTGACGATGCCGTTGCCGCGATGGACGGCCTCA
AGGAGGAAAAATGA

Upstream 100 bases:

>100_bases
GATCCGCGCTGCCAAGCCACTGGATTTCCATCGAGACTTCACGCTAATCCTGATATTGTCGTGTTTGGCGCGAGAACTCC
GGTGAGGATCACGGTGCGGC

Downstream 100 bases:

>100_bases
CGCATATTTATGAGCCTCGTCTGTCTCGTATTGCCATCGACAAGTTACGACCGACGCAGATCGCGGTGGGCTTCCGCGAG
GTCGAACTGAAAAGAAAGGA

Product: sulfate permease

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MGNNGRDILAGLSVAGLMLPEAIAYSGIAGVPPQHALYAAMAGCLVYALLGQSRFAIISPTSSSAAILAAMLAALVPQPG
QKMLLVAVAVFLVGLFFLAAGTLRLGALSSIISRPVLRGFAFGLAILISLKQFPAIFGMPQAGAGTFEAILQILTNPGQW
NGFSLSIGIAALILLLFARRYPQIPGSLIIIALAIPISVMFDLQQRGVDVVGPIDLSGIWGSVTTLSLDELAHVARFAPP
LVLILFAESWGTIRGLSLRHGEDVDANRELKTLGIANVASAALQGMPVGAGFSAGAASEAANPRTRMASAIAAIGLAGFT
FAAADWFAYIPHAALSAIIIVALLHALDPSPFLRLWRLRQDLVLALAATAGVLFLGVLNGMLAAIVLSFAVFLQRLSSPR
IVMLGRLGASHDFVDVKRHPDAAEPAGMLVLRPAQPLFFGNAEPTFAEITRRILASPDINAVIISLEETFELDTTALEAL
LEFDASLRGRNIGIRYAPMHDAVRDVVAAGGGDDLLRRANYSVDDAVAAMDGLKEEK

Sequences:

>Translated_537_residues
MGNNGRDILAGLSVAGLMLPEAIAYSGIAGVPPQHALYAAMAGCLVYALLGQSRFAIISPTSSSAAILAAMLAALVPQPG
QKMLLVAVAVFLVGLFFLAAGTLRLGALSSIISRPVLRGFAFGLAILISLKQFPAIFGMPQAGAGTFEAILQILTNPGQW
NGFSLSIGIAALILLLFARRYPQIPGSLIIIALAIPISVMFDLQQRGVDVVGPIDLSGIWGSVTTLSLDELAHVARFAPP
LVLILFAESWGTIRGLSLRHGEDVDANRELKTLGIANVASAALQGMPVGAGFSAGAASEAANPRTRMASAIAAIGLAGFT
FAAADWFAYIPHAALSAIIIVALLHALDPSPFLRLWRLRQDLVLALAATAGVLFLGVLNGMLAAIVLSFAVFLQRLSSPR
IVMLGRLGASHDFVDVKRHPDAAEPAGMLVLRPAQPLFFGNAEPTFAEITRRILASPDINAVIISLEETFELDTTALEAL
LEFDASLRGRNIGIRYAPMHDAVRDVVAAGGGDDLLRRANYSVDDAVAAMDGLKEEK
>Mature_536_residues
GNNGRDILAGLSVAGLMLPEAIAYSGIAGVPPQHALYAAMAGCLVYALLGQSRFAIISPTSSSAAILAAMLAALVPQPGQ
KMLLVAVAVFLVGLFFLAAGTLRLGALSSIISRPVLRGFAFGLAILISLKQFPAIFGMPQAGAGTFEAILQILTNPGQWN
GFSLSIGIAALILLLFARRYPQIPGSLIIIALAIPISVMFDLQQRGVDVVGPIDLSGIWGSVTTLSLDELAHVARFAPPL
VLILFAESWGTIRGLSLRHGEDVDANRELKTLGIANVASAALQGMPVGAGFSAGAASEAANPRTRMASAIAAIGLAGFTF
AAADWFAYIPHAALSAIIIVALLHALDPSPFLRLWRLRQDLVLALAATAGVLFLGVLNGMLAAIVLSFAVFLQRLSSPRI
VMLGRLGASHDFVDVKRHPDAAEPAGMLVLRPAQPLFFGNAEPTFAEITRRILASPDINAVIISLEETFELDTTALEALL
EFDASLRGRNIGIRYAPMHDAVRDVVAAGGGDDLLRRANYSVDDAVAAMDGLKEEK

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=486, Percent_Identity=25.7201646090535, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI39752683, Length=486, Percent_Identity=25.7201646090535, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI269784651, Length=482, Percent_Identity=23.4439834024896, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI94721259, Length=460, Percent_Identity=27.1739130434783, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI94721255, Length=460, Percent_Identity=27.3913043478261, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI94721253, Length=460, Percent_Identity=27.3913043478261, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI45827802, Length=435, Percent_Identity=26.6666666666667, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI94721257, Length=460, Percent_Identity=27.1739130434783, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI47131207, Length=483, Percent_Identity=27.9503105590062, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI20336272, Length=483, Percent_Identity=27.9503105590062, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI4557535, Length=475, Percent_Identity=22.3157894736842, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI262206105, Length=134, Percent_Identity=40.2985074626866, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI262206075, Length=134, Percent_Identity=40.2985074626866, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI262206069, Length=134, Percent_Identity=40.2985074626866, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI262206063, Length=134, Percent_Identity=40.2985074626866, Blast_Score=86, Evalue=8e-17,
Organism=Homo sapiens, GI100913030, Length=491, Percent_Identity=21.5885947046843, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4505697, Length=478, Percent_Identity=21.7573221757322, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI16418413, Length=483, Percent_Identity=22.1532091097308, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI16418457, Length=537, Percent_Identity=20.8566108007449, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI301601599, Length=537, Percent_Identity=20.8566108007449, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI217272867, Length=483, Percent_Identity=22.1532091097308, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI45827804, Length=241, Percent_Identity=27.3858921161826, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87081859, Length=546, Percent_Identity=24.3589743589744, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551690, Length=589, Percent_Identity=23.2597623089983, Blast_Score=121, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17566848, Length=474, Percent_Identity=24.2616033755274, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI86564196, Length=485, Percent_Identity=22.0618556701031, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562578, Length=478, Percent_Identity=24.0585774058577, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI86565215, Length=526, Percent_Identity=22.8136882129278, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI86564876, Length=511, Percent_Identity=20.5479452054795, Blast_Score=79, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6325260, Length=564, Percent_Identity=23.936170212766, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6319771, Length=452, Percent_Identity=22.1238938053097, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6323121, Length=159, Percent_Identity=27.0440251572327, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21358633, Length=432, Percent_Identity=26.1574074074074, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24649801, Length=439, Percent_Identity=25.9681093394077, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24651449, Length=173, Percent_Identity=28.3236994219653, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21358229, Length=163, Percent_Identity=33.7423312883436, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI85815873, Length=493, Percent_Identity=26.369168356998, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355087, Length=160, Percent_Identity=30.625, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647160, Length=160, Percent_Identity=30.625, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922482, Length=179, Percent_Identity=30.7262569832402, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24663084, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21357695, Length=184, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 56346; Mature: 56215

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNNGRDILAGLSVAGLMLPEAIAYSGIAGVPPQHALYAAMAGCLVYALLGQSRFAIISP
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECC
TSSSAAILAAMLAALVPQPGQKMLLVAVAVFLVGLFFLAAGTLRLGALSSIISRPVLRGF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGLAILISLKQFPAIFGMPQAGAGTFEAILQILTNPGQWNGFSLSIGIAALILLLFARR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
YPQIPGSLIIIALAIPISVMFDLQQRGVDVVGPIDLSGIWGSVTTLSLDELAHVARFAPP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHEEEHHHHHHHHHHCCH
LVLILFAESWGTIRGLSLRHGEDVDANRELKTLGIANVASAALQGMPVGAGFSAGAASEA
HEEEEECCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ANPRTRMASAIAAIGLAGFTFAAADWFAYIPHAALSAIIIVALLHALDPSPFLRLWRLRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DLVLALAATAGVLFLGVLNGMLAAIVLSFAVFLQRLSSPRIVMLGRLGASHDFVDVKRHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCCC
DAAEPAGMLVLRPAQPLFFGNAEPTFAEITRRILASPDINAVIISLEETFELDTTALEAL
CCCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHCHHHHHHHHH
LEFDASLRGRNIGIRYAPMHDAVRDVVAAGGGDDLLRRANYSVDDAVAAMDGLKEEK
HHHHHHCCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GNNGRDILAGLSVAGLMLPEAIAYSGIAGVPPQHALYAAMAGCLVYALLGQSRFAIISP
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECC
TSSSAAILAAMLAALVPQPGQKMLLVAVAVFLVGLFFLAAGTLRLGALSSIISRPVLRGF
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGLAILISLKQFPAIFGMPQAGAGTFEAILQILTNPGQWNGFSLSIGIAALILLLFARR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHH
YPQIPGSLIIIALAIPISVMFDLQQRGVDVVGPIDLSGIWGSVTTLSLDELAHVARFAPP
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHEEEHHHHHHHHHHCCH
LVLILFAESWGTIRGLSLRHGEDVDANRELKTLGIANVASAALQGMPVGAGFSAGAASEA
HEEEEECCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
ANPRTRMASAIAAIGLAGFTFAAADWFAYIPHAALSAIIIVALLHALDPSPFLRLWRLRQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DLVLALAATAGVLFLGVLNGMLAAIVLSFAVFLQRLSSPRIVMLGRLGASHDFVDVKRHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCCC
DAAEPAGMLVLRPAQPLFFGNAEPTFAEITRRILASPDINAVIISLEETFELDTTALEAL
CCCCCCCEEEECCCCCEEECCCCCHHHHHHHHHHCCCCCCEEEEEEHHHHCHHHHHHHHH
LEFDASLRGRNIGIRYAPMHDAVRDVVAAGGGDDLLRRANYSVDDAVAAMDGLKEEK
HHHHHHCCCCCCCEEECCHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]