BacMap

Definition	Agrobacterium tumefaciens str. C58 chromosome circular, complete sequence.
Accession	NC_003062
Length	2,841,580

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The map label for this gene is znuC

Identifier: 15888845

GI number: 15888845

Start: 1509837

End: 1510736

Strand: Reverse

Name: znuC

Synonym: Atu1520

Alternate gene names: 15888845

Gene position: 1510736-1509837 (Counterclockwise)

Preceding gene: 159184798

Following gene: 159184796

Centisome position: 53.17

GC content: 61.33

Gene sequence:

>900_bases
ATGCTTCACTCAGCCCACAAGGGCAACGAAATACTGGTTTCCCTCGCCAATGCCGGCGTGCAGCGCAACGGCCGCTGGCT
GGTGCGTGGCGTGGAGTTTTCCGTCAGCAAGGGCGAGATCGTCACGCTGATCGGCCCGAACGGCTCCGGCAAATCCACCA
GCGCAAAAATGGCGATCGGTGTCGCGAAACCGAGCGAGGGCAAGGTCTCGCGCAAGGCCGGTCTGCGCGTGGGTTATGTG
CCGCAGAAGCTTTCGGTGGATTGGACGATGCCACTTTCCGTGCGCCGGCTGATGACGCTAACCGGGCCGCTGCCTGCGCG
GGAAATCGACGCGGCGCTGAATGCGACAGGCATCGCACATCTTGCCAATGCCGAGGTGCAGCATCTTTCCGGCGGCGAAT
TCCAGCGCGCACTTCTGGCCCGCGCCATTGCCCGCAAGCCCGATCTGCTGGTTCTCGACGAGCCCGTTCAGGGTGTCGAT
TTTTCCGGTGAGATCGCTCTCTACGATCTTATTAAAAATATCAGGAATTCAAATGATTGCGGCATTCTGTTAATCTCGCA
TGACCTGCATGTTGTGATGGCGGAAACCGATACCGTGATCTGCCTGAACGGCCATGTCTGCTGCCGCGGCACGCCGCAGG
CGGTGAGCCAGAGCCCGGAATATATGCGGCTTTTCGGTGGCACGGCGGCCAAGGCGCTGGCGGTCTACAGCCACCATCAC
GACCACACCCATCTGCCCGATGGCCGGGTGCAGCATGCGGATGGAACGGTGACGGACCATTGCCATCCCGAGGACGGGCA
CCACCATGATGAGGATGGCGAATGCGGTTGCGGCCATGATCATGGGGAGCATGGGGACCATGCGCCCGACGGCCTTCGGC
AGGGAGAACGCCATGTTTGA

Upstream 100 bases:

>100_bases
TGCACTCCACTTGAACAAGTATAGTTATGTTATTACATTTATTGCGTAACTCTATAACGTATGCAATAGCGGTAGGCAAC
ATCGCTGAACGGACAATCCC

Downstream 100 bases:

>100_bases
CGATTTCTTCGTACGCGCCATGGTCGCCGGCATTGGCGTTGCGCTCACCGCCGGTCCTCTCGGCTGTTTCGTCGTCTGGC
GGCGCATGGCCTATTTCGGT

Product: ABC transporter, nucleotide binding/ATPase protein (zinc)

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLHSAHKGNEILVSLANAGVQRNGRWLVRGVEFSVSKGEIVTLIGPNGSGKSTSAKMAIGVAKPSEGKVSRKAGLRVGYV
PQKLSVDWTMPLSVRRLMTLTGPLPAREIDAALNATGIAHLANAEVQHLSGGEFQRALLARAIARKPDLLVLDEPVQGVD
FSGEIALYDLIKNIRNSNDCGILLISHDLHVVMAETDTVICLNGHVCCRGTPQAVSQSPEYMRLFGGTAAKALAVYSHHH
DHTHLPDGRVQHADGTVTDHCHPEDGHHHDEDGECGCGHDHGEHGDHAPDGLRQGERHV

Sequences:

>Translated_299_residues
MLHSAHKGNEILVSLANAGVQRNGRWLVRGVEFSVSKGEIVTLIGPNGSGKSTSAKMAIGVAKPSEGKVSRKAGLRVGYV
PQKLSVDWTMPLSVRRLMTLTGPLPAREIDAALNATGIAHLANAEVQHLSGGEFQRALLARAIARKPDLLVLDEPVQGVD
FSGEIALYDLIKNIRNSNDCGILLISHDLHVVMAETDTVICLNGHVCCRGTPQAVSQSPEYMRLFGGTAAKALAVYSHHH
DHTHLPDGRVQHADGTVTDHCHPEDGHHHDEDGECGCGHDHGEHGDHAPDGLRQGERHV
>Mature_299_residues
MLHSAHKGNEILVSLANAGVQRNGRWLVRGVEFSVSKGEIVTLIGPNGSGKSTSAKMAIGVAKPSEGKVSRKAGLRVGYV
PQKLSVDWTMPLSVRRLMTLTGPLPAREIDAALNATGIAHLANAEVQHLSGGEFQRALLARAIARKPDLLVLDEPVQGVD
FSGEIALYDLIKNIRNSNDCGILLISHDLHVVMAETDTVICLNGHVCCRGTPQAVSQSPEYMRLFGGTAAKALAVYSHHH
DHTHLPDGRVQHADGTVTDHCHPEDGHHHDEDGECGCGHDHGEHGDHAPDGLRQGERHV

Specific function: Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system

COG id: COG1121

COG function: function code P; ABC-type Mn/Zn transport systems, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI27436953, Length=205, Percent_Identity=31.7073170731707, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI27477115, Length=212, Percent_Identity=30.6603773584906, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI153792144, Length=212, Percent_Identity=29.7169811320755, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI6005701, Length=207, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI31657092, Length=212, Percent_Identity=30.188679245283, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI255708477, Length=237, Percent_Identity=25.7383966244726, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI108773784, Length=190, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI108773782, Length=190, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI27881506, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI148612844, Length=234, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI10947137, Length=187, Percent_Identity=28.3422459893048, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI69354671, Length=167, Percent_Identity=26.3473053892216, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI10947135, Length=167, Percent_Identity=26.3473053892216, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI116734710, Length=222, Percent_Identity=29.2792792792793, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788165, Length=239, Percent_Identity=50.6276150627615, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI87081709, Length=244, Percent_Identity=29.0983606557377, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789593, Length=231, Percent_Identity=30.7359307359307, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790739, Length=222, Percent_Identity=30.1801801801802, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786345, Length=237, Percent_Identity=27.0042194092827, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789864, Length=251, Percent_Identity=29.0836653386454, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786803, Length=217, Percent_Identity=28.110599078341, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787758, Length=213, Percent_Identity=27.2300469483568, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787370, Length=232, Percent_Identity=22.8448275862069, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87081791, Length=302, Percent_Identity=26.8211920529801, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788506, Length=228, Percent_Identity=29.3859649122807, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789891, Length=204, Percent_Identity=27.9411764705882, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081834, Length=182, Percent_Identity=31.8681318681319, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789032, Length=280, Percent_Identity=26.4285714285714, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081782, Length=145, Percent_Identity=35.8620689655172, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787182, Length=196, Percent_Identity=30.1020408163265, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789873, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788761, Length=209, Percent_Identity=27.7511961722488, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1790544, Length=218, Percent_Identity=24.3119266055046, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994943, Length=208, Percent_Identity=28.8461538461538, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786703, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786975, Length=209, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787029, Length=238, Percent_Identity=24.3697478991597, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789890, Length=231, Percent_Identity=25.5411255411255, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789751, Length=180, Percent_Identity=26.1111111111111, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790190, Length=218, Percent_Identity=27.0642201834862, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786398, Length=218, Percent_Identity=27.0642201834862, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789991, Length=204, Percent_Identity=25.9803921568627, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788450, Length=231, Percent_Identity=26.4069264069264, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787164, Length=190, Percent_Identity=27.8947368421053, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI2367384, Length=188, Percent_Identity=29.7872340425532, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790467, Length=207, Percent_Identity=24.1545893719807, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789586, Length=230, Percent_Identity=26.9565217391304, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=205, Percent_Identity=28.780487804878, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17559834, Length=168, Percent_Identity=27.3809523809524, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533608, Length=208, Percent_Identity=29.8076923076923, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17555318, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17510237, Length=197, Percent_Identity=24.3654822335025, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193211017, Length=212, Percent_Identity=26.8867924528302, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=212, Percent_Identity=26.8867924528302, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=212, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17569081, Length=144, Percent_Identity=31.25, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555800, Length=186, Percent_Identity=26.8817204301075, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=212, Percent_Identity=25.4716981132075, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=212, Percent_Identity=25.4716981132075, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=212, Percent_Identity=25.4716981132075, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=212, Percent_Identity=25.4716981132075, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6321121, Length=217, Percent_Identity=30.4147465437788, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320296, Length=186, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641342, Length=163, Percent_Identity=31.2883435582822, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666836, Length=191, Percent_Identity=30.8900523560209, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24642252, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859989, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI85725262, Length=226, Percent_Identity=26.9911504424779, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24661270, Length=197, Percent_Identity=29.4416243654822, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355589, Length=197, Percent_Identity=29.4416243654822, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574150, Length=195, Percent_Identity=28.7179487179487, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI116007328, Length=195, Percent_Identity=28.7179487179487, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNUC_AGRT5 (Q8UF79)

Other databases:

- EMBL:   AE007869
- PIR:   AG2763
- PIR:   F97544
- RefSeq:   NP_354526.1
- ProteinModelPortal:   Q8UF79
- SMR:   Q8UF79
- STRING:   Q8UF79
- GeneID:   1133558
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu1520
- eggNOG:   COG1121
- HOGENOM:   HBG758042
- OMA:   AGIAHML
- PhylomeDB:   Q8UF79
- ProtClustDB:   CLSK881518
- BioCyc:   ATUM176299-1:ATU1520-MONOMER
- HAMAP:   MF_01725
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017882
- InterPro:   IPR003593
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 32085; Mature: 32085

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51298 ZNUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHSAHKGNEILVSLANAGVQRNGRWLVRGVEFSVSKGEIVTLIGPNGSGKSTSAKMAIG
CCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCCCEEEEEE
VAKPSEGKVSRKAGLRVGYVPQKLSVDWTMPLSVRRLMTLTGPLPAREIDAALNATGIAH
ECCCCCCCCHHHHCCEEECCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHCCCCHHH
LANAEVQHLSGGEFQRALLARAIARKPDLLVLDEPVQGVDFSGEIALYDLIKNIRNSNDC
HCCCHHEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCC
GILLISHDLHVVMAETDTVICLNGHVCCRGTPQAVSQSPEYMRLFGGTAAKALAVYSHHH
EEEEEECCEEEEEECCCEEEEECCEEEECCCHHHHHCCCHHEEECCCHHHHHHHHHHCCC
DHTHLPDGRVQHADGTVTDHCHPEDGHHHDEDGECGCGHDHGEHGDHAPDGLRQGERHV
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MLHSAHKGNEILVSLANAGVQRNGRWLVRGVEFSVSKGEIVTLIGPNGSGKSTSAKMAIG
CCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCCEEEEECCCCCCCCCCEEEEEE
VAKPSEGKVSRKAGLRVGYVPQKLSVDWTMPLSVRRLMTLTGPLPAREIDAALNATGIAH
ECCCCCCCCHHHHCCEEECCCCEEEEEEECCHHHHHHHHHCCCCCHHHHHHHHCCCCHHH
LANAEVQHLSGGEFQRALLARAIARKPDLLVLDEPVQGVDFSGEIALYDLIKNIRNSNDC
HCCCHHEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCC
GILLISHDLHVVMAETDTVICLNGHVCCRGTPQAVSQSPEYMRLFGGTAAKALAVYSHHH
EEEEEECCEEEEEECCCEEEEECCEEEECCCHHHHHCCCHHEEECCCHHHHHHHHHHCCC
DHTHLPDGRVQHADGTVTDHCHPEDGHHHDEDGECGCGHDHGEHGDHAPDGLRQGERHV
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194