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The map label for this gene is cysI [H]

Identifier: 15888782

GI number: 15888782

Start: 1451652

End: 1453322

Strand: Direct

Name: cysI [H]

Synonym: Atu1456

Alternate gene names: 15888782

Gene position: 1451652-1453322 (Clockwise)

Preceding gene: 15888781

Following gene: 159184767

Centisome position: 51.09

GC content: 60.2

Gene sequence:

>1671_bases
ATGTACCGTTACGACGAATTCGATCACGCATTTGTTGAAGGCCGCGTGGCGCAGTTTCGCGATCAGGTCGAGCGCCGGTT
ATCGGGCGAGTTGGCCGAGGACGCATTCAAGCCGCTGCGCCTGATGAATGGTGTCTATCTTCAGCTCCACGCCTACATGC
TGCGCGTCGCCATTCCCTACGGTACGCTGAATTCGCAACAGATGCGGATGCTTGCCCATATCGCCCGCAAATATGACCGG
GGTTATGGCCATTTCACCACCCGCCAGAACATCCAGTACAACTGGCCGCGCCTCTCGGACACGCCGGATATCCTCTCTGA
ACTGGCAAGCGTGGAAATGCACGCACTGCAGACGTCGGGTAACTGCATTCGCAACGTGACCGCCGATCATTTCGCGGGTG
CTGCCGCAGACGAAGTCGCCGATCCGCGTCCCTATGCGGAAATCCTGCGTCAATGGTCTTCCGTGCATCCGGAATTCTCG
TTCCTGCCGCGCAAGTTCAAGATCGCGGTGACGGGTGCCGAGCGCGACCGCGCCGCCATTCAGGTCCACGATATCGGCCT
GCATCTGAAAAAGAACGACAAGGGTGAGATCGGTTTTGCCGTTTACGTCGGCGGCGGGCAGGGCCGTACGCCGATGATCG
CCAAGAAGATTCGCGACTTCCTGCCGGAAGAGGACCTGCTGTCCTATACCACGGCCGTCATGCGCGTTTATAACCTGCAC
GGCCGCCGCGACAACAAATACAAGGCGCGCATCAAGATTCTCGTACATGAAACCGGCGCAGAAGAACTGGCCCGCCAGGT
CGAGGTTGAATTCGCGGAGCTGAAAAACACCGAATTGAAGCTGCCGGATGCCGATATTGCCGCCATCACCGCCTATTTCG
CCCCGCCGGCGCTGAAAGACCGCCCTGAAGGCTGGGAAAGCCTGGCGCGCTGGAAGCGTGCGGATGAAGGTTTTGCCCGT
TTTGTCGAGCAGAACGTCGCGCCGCACAAGCACCCGGACTACGGCATGGTGACGATTTCGCTGAAGCCGATCGGCGGCAT
TCCGGGCGACGCGACCGACGAGCAGATGGAACTCGTCGCCGACATCGCCGCCGAATATGCCTTTGACGAAATCCGCATCA
GTCACGAGCAGAACATCATCCTGCCGCATGTGGCGCTGGCCGATCTCGAGCCGGTCTATCGTGCGCTCGTGGGCGCGGGA
CTGGCGACTGCCAATGCCGGGCTGATCACCGATATCATTGCCTGTCCCGGGCTGGACTATTGCGCGCTTGCCAATGCCCG
CTCCATTCCGGTGGCGCAGGAGATCTCCACCCGTTTCGGCGCGCCCGAACGTCAGGCCGAGATCGGCGAGCTGAAGATCA
AGATTTCCGGCTGCATCAACGCCTGCGGCCACCACCATGTCGGCCATATCGGCCTTCTGGGCGTGGAGAAGAAGGGTGCC
GAACTCTACCAGATCACGCTTGGCGGATCGGGTGATGAAAACACCTCGATTGGTGAAATCATTGGCCGCGGTTTCGAGCC
GGAAAAAGTGACCGACGCGGTGGAAACCATTGTCGACACTTATCTGGGCTTGCGCCTTTCGAAGGAAGAAACCTTCCTCG
AAGCCTATCGCCGCGTCGGACCGCAGCCGTTCAAGGACGCGCTCTACGGTTCCGCCGCCGAAGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCGGCTTCGCGAGCGCATCCGCGCCGCCGGCCCCACCATGCACTATGCCACCGGCTACAAGCCGGCCGATGCAGCATTT
ATCGCAGTCTGAGGAAGAAT

Downstream 100 bases:

>100_bases
GGAAATGGATATGACGAAAATCTGGACCCGCGACGGCTTTGCGGAAAACGATCCATGGGTGATCGAAACGGAAGAGGTGA
AGGCAACGGGCGAGCAGAAG

Product: sulfite reductase (NADPH) hemoprotein beta-component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MYRYDEFDHAFVEGRVAQFRDQVERRLSGELAEDAFKPLRLMNGVYLQLHAYMLRVAIPYGTLNSQQMRMLAHIARKYDR
GYGHFTTRQNIQYNWPRLSDTPDILSELASVEMHALQTSGNCIRNVTADHFAGAAADEVADPRPYAEILRQWSSVHPEFS
FLPRKFKIAVTGAERDRAAIQVHDIGLHLKKNDKGEIGFAVYVGGGQGRTPMIAKKIRDFLPEEDLLSYTTAVMRVYNLH
GRRDNKYKARIKILVHETGAEELARQVEVEFAELKNTELKLPDADIAAITAYFAPPALKDRPEGWESLARWKRADEGFAR
FVEQNVAPHKHPDYGMVTISLKPIGGIPGDATDEQMELVADIAAEYAFDEIRISHEQNIILPHVALADLEPVYRALVGAG
LATANAGLITDIIACPGLDYCALANARSIPVAQEISTRFGAPERQAEIGELKIKISGCINACGHHHVGHIGLLGVEKKGA
ELYQITLGGSGDENTSIGEIIGRGFEPEKVTDAVETIVDTYLGLRLSKEETFLEAYRRVGPQPFKDALYGSAAEAA

Sequences:

>Translated_556_residues
MYRYDEFDHAFVEGRVAQFRDQVERRLSGELAEDAFKPLRLMNGVYLQLHAYMLRVAIPYGTLNSQQMRMLAHIARKYDR
GYGHFTTRQNIQYNWPRLSDTPDILSELASVEMHALQTSGNCIRNVTADHFAGAAADEVADPRPYAEILRQWSSVHPEFS
FLPRKFKIAVTGAERDRAAIQVHDIGLHLKKNDKGEIGFAVYVGGGQGRTPMIAKKIRDFLPEEDLLSYTTAVMRVYNLH
GRRDNKYKARIKILVHETGAEELARQVEVEFAELKNTELKLPDADIAAITAYFAPPALKDRPEGWESLARWKRADEGFAR
FVEQNVAPHKHPDYGMVTISLKPIGGIPGDATDEQMELVADIAAEYAFDEIRISHEQNIILPHVALADLEPVYRALVGAG
LATANAGLITDIIACPGLDYCALANARSIPVAQEISTRFGAPERQAEIGELKIKISGCINACGHHHVGHIGLLGVEKKGA
ELYQITLGGSGDENTSIGEIIGRGFEPEKVTDAVETIVDTYLGLRLSKEETFLEAYRRVGPQPFKDALYGSAAEAA
>Mature_556_residues
MYRYDEFDHAFVEGRVAQFRDQVERRLSGELAEDAFKPLRLMNGVYLQLHAYMLRVAIPYGTLNSQQMRMLAHIARKYDR
GYGHFTTRQNIQYNWPRLSDTPDILSELASVEMHALQTSGNCIRNVTADHFAGAAADEVADPRPYAEILRQWSSVHPEFS
FLPRKFKIAVTGAERDRAAIQVHDIGLHLKKNDKGEIGFAVYVGGGQGRTPMIAKKIRDFLPEEDLLSYTTAVMRVYNLH
GRRDNKYKARIKILVHETGAEELARQVEVEFAELKNTELKLPDADIAAITAYFAPPALKDRPEGWESLARWKRADEGFAR
FVEQNVAPHKHPDYGMVTISLKPIGGIPGDATDEQMELVADIAAEYAFDEIRISHEQNIILPHVALADLEPVYRALVGAG
LATANAGLITDIIACPGLDYCALANARSIPVAQEISTRFGAPERQAEIGELKIKISGCINACGHHHVGHIGLLGVEKKGA
ELYQITLGGSGDENTSIGEIIGRGFEPEKVTDAVETIVDTYLGLRLSKEETFLEAYRRVGPQPFKDALYGSAAEAA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 61721; Mature: 61721

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRYDEFDHAFVEGRVAQFRDQVERRLSGELAEDAFKPLRLMNGVYLQLHAYMLRVAIPY
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GTLNSQQMRMLAHIARKYDRGYGHFTTRQNIQYNWPRLSDTPDILSELASVEMHALQTSG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHCCC
NCIRNVTADHFAGAAADEVADPRPYAEILRQWSSVHPEFSFLPRKFKIAVTGAERDRAAI
CHHHCCCHHHHCCCCHHHCCCCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCCEE
QVHDIGLHLKKNDKGEIGFAVYVGGGQGRTPMIAKKIRDFLPEEDLLSYTTAVMRVYNLH
EEEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GRRDNKYKARIKILVHETGAEELARQVEVEFAELKNTELKLPDADIAAITAYFAPPALKD
CCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCCCCCC
RPEGWESLARWKRADEGFARFVEQNVAPHKHPDYGMVTISLKPIGGIPGDATDEQMELVA
CCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHH
DIAAEYAFDEIRISHEQNIILPHVALADLEPVYRALVGAGLATANAGLITDIIACPGLDY
HHHHHHHHHHHEECCCCCEEECHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCCH
CALANARSIPVAQEISTRFGAPERQAEIGELKIKISGCINACGHHHVGHIGLLGVEKKGA
HHHCCCCCCCHHHHHHHHCCCCHHCCCCCEEEEEEEHHHHHCCCCCCCCEEEEEECCCCC
ELYQITLGGSGDENTSIGEIIGRGFEPEKVTDAVETIVDTYLGLRLSKEETFLEAYRRVG
EEEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHCC
PQPFKDALYGSAAEAA
CCCHHHHHCCCCCCCC
>Mature Secondary Structure
MYRYDEFDHAFVEGRVAQFRDQVERRLSGELAEDAFKPLRLMNGVYLQLHAYMLRVAIPY
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GTLNSQQMRMLAHIARKYDRGYGHFTTRQNIQYNWPRLSDTPDILSELASVEMHALQTSG
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHCCC
NCIRNVTADHFAGAAADEVADPRPYAEILRQWSSVHPEFSFLPRKFKIAVTGAERDRAAI
CHHHCCCHHHHCCCCHHHCCCCCHHHHHHHHHHHCCCCHHCCCCEEEEEEECCCCCCCEE
QVHDIGLHLKKNDKGEIGFAVYVGGGQGRTPMIAKKIRDFLPEEDLLSYTTAVMRVYNLH
EEEEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GRRDNKYKARIKILVHETGAEELARQVEVEFAELKNTELKLPDADIAAITAYFAPPALKD
CCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCCCCCC
RPEGWESLARWKRADEGFARFVEQNVAPHKHPDYGMVTISLKPIGGIPGDATDEQMELVA
CCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHH
DIAAEYAFDEIRISHEQNIILPHVALADLEPVYRALVGAGLATANAGLITDIIACPGLDY
HHHHHHHHHHHEECCCCCEEECHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCCH
CALANARSIPVAQEISTRFGAPERQAEIGELKIKISGCINACGHHHVGHIGLLGVEKKGA
HHHCCCCCCCHHHHHHHHCCCCHHCCCCCEEEEEEEHHHHHCCCCCCCCEEEEEECCCCC
ELYQITLGGSGDENTSIGEIIGRGFEPEKVTDAVETIVDTYLGLRLSKEETFLEAYRRVG
EEEEEEECCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHCCEECCHHHHHHHHHHCC
PQPFKDALYGSAAEAA
CCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA