Click here to switch to the map view.

The map label for this gene is trkA [H]

Identifier: 15888774

GI number: 15888774

Start: 1444563

End: 1445939

Strand: Direct

Name: trkA [H]

Synonym: Atu1449

Alternate gene names: 15888774

Gene position: 1444563-1445939 (Clockwise)

Preceding gene: 15888773

Following gene: 17935350

Centisome position: 50.84

GC content: 57.81

Gene sequence:

>1377_bases
ATGAAAGTCATCATTTGCGGCGCAGGGCAGGTGGGTTACGGCATCGCCGAACAATTGTCGCGGGAGGATAACGAAGTATC
GGTCATCGATACGGCCGCGCCGCTGATTACCGCCATTACCGAGACGCTGGATGTGCGCGGTTATGTCGGCCACGGCGCCC
ATCCCGACATGCTGGCCAAGGCCGGTGCGGATCAGGCCGACATGATCATCGCGGTGACATTGCATGACGAGATCAATATC
GTCGCCTGCGAAGTGGCGCACGCACTCTTCAGCGTGCCGACCAAGATTGCCCGTATCCGCGACCAGAGCTATATGAAGCC
GGAATATGCCGATCTCTTCAGCCGCGAGAACATGTCCATCGATGTGACGATTTCCCCGGAAGTAGAAGTCGGCAAGATGG
TGCTGCGGCGCATCGCCTTTCCGGGTGCTACCGATGTGGTGCGCTTTGCCGAAGATACGATCTACATGCTTGCCATCGAA
TGCATGGAAGATTGCCCCGTTATCAACACGCCGCTGCAGCAGCTTTCGAGCCTGTTTCCGGACCTCATAGCCACGGTGGT
GGGTGTCTATCGTGACGGCATTCTCAAAGTGGCGCATTCGTCGGAGCAATTGCGCGTGGGCGACCTCGCCTATGTCATCT
GTCAACGCCAGCATGCACGCCGCACCTTGAGCCTCTTTGGCCATGAAGAGCAGGAGGCGCAGCGCATCGTCATTGCAGGC
GCCGGTAATATCGGCCATTTCGTCGCGCATAAAATCGAGGAAATGCAGTCGAAAACGCGGGTGAAGATCATCGAGGCCGA
TCGCGACAGGGCGATTGCCGCATCCGAACAGCTGAGCCATACCATCGTCATGCATGGCTCGGCCCTCGACCAGAAAATTC
TGATGCAGGCGGATATCCAGGATGCCGATCTGATCGTCACGCTCACCAATAACGACCAGACCAATATTCTGGCCGCCGTC
ATCGCCAAGCAGCTCGGCTGCAAATCGAACCTGGCGCTGCTGAACAGTACCTCTTTCCATGATGTCGCCCGCTCGCTCGG
ACTCGATGCCTATATCAACCCCCGGGCGGTCACGATCTCCCGCGTGCTGCAACATGTACGCAAAGGCCGTATCCGCTCGG
TTTATGCCGTTCAGCGCGGTTCGGCTGAGGTAATCGAGGCGGAAGCGCTTGAAACATCGCCGCTGGTCGGCCAGTCTTTC
CGTGATATCGATATGCCCGACGGCGTGCGCATTGGCGCGATCTATCGCGACGGTGTGGTGATCCGTCCGGATGGCAGCAC
GAAGATCAAGGCGAAGGATCGCGTCGTGCTGTTTGCTTCCGCCGATGCCGTGCGGGACGTGGAACAACTTTTCCGTGTTT
CGATACAATATTTTTGA

Upstream 100 bases:

>100_bases
CGGCATGGAACGGTCGGCGCTGCATCGCAAACTGAAATCTCTCGGCGTATAAGGAACCAAGGCACCTCGTCGCAACCGAT
TATTCCGTCAGAGAGACAGC

Downstream 100 bases:

>100_bases
CTGTCCCGAATCGAAAAAGCGGGTCAATACTCGTACTCATTTGGCTGTTTTCGCCGTTGCGGAACGGAACATGATTTGAT
ACCAGAGTTTGAGGTCGGCC

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKVIICGAGQVGYGIAEQLSREDNEVSVIDTAAPLITAITETLDVRGYVGHGAHPDMLAKAGADQADMIIAVTLHDEINI
VACEVAHALFSVPTKIARIRDQSYMKPEYADLFSRENMSIDVTISPEVEVGKMVLRRIAFPGATDVVRFAEDTIYMLAIE
CMEDCPVINTPLQQLSSLFPDLIATVVGVYRDGILKVAHSSEQLRVGDLAYVICQRQHARRTLSLFGHEEQEAQRIVIAG
AGNIGHFVAHKIEEMQSKTRVKIIEADRDRAIAASEQLSHTIVMHGSALDQKILMQADIQDADLIVTLTNNDQTNILAAV
IAKQLGCKSNLALLNSTSFHDVARSLGLDAYINPRAVTISRVLQHVRKGRIRSVYAVQRGSAEVIEAEALETSPLVGQSF
RDIDMPDGVRIGAIYRDGVVIRPDGSTKIKAKDRVVLFASADAVRDVEQLFRVSIQYF

Sequences:

>Translated_458_residues
MKVIICGAGQVGYGIAEQLSREDNEVSVIDTAAPLITAITETLDVRGYVGHGAHPDMLAKAGADQADMIIAVTLHDEINI
VACEVAHALFSVPTKIARIRDQSYMKPEYADLFSRENMSIDVTISPEVEVGKMVLRRIAFPGATDVVRFAEDTIYMLAIE
CMEDCPVINTPLQQLSSLFPDLIATVVGVYRDGILKVAHSSEQLRVGDLAYVICQRQHARRTLSLFGHEEQEAQRIVIAG
AGNIGHFVAHKIEEMQSKTRVKIIEADRDRAIAASEQLSHTIVMHGSALDQKILMQADIQDADLIVTLTNNDQTNILAAV
IAKQLGCKSNLALLNSTSFHDVARSLGLDAYINPRAVTISRVLQHVRKGRIRSVYAVQRGSAEVIEAEALETSPLVGQSF
RDIDMPDGVRIGAIYRDGVVIRPDGSTKIKAKDRVVLFASADAVRDVEQLFRVSIQYF
>Mature_458_residues
MKVIICGAGQVGYGIAEQLSREDNEVSVIDTAAPLITAITETLDVRGYVGHGAHPDMLAKAGADQADMIIAVTLHDEINI
VACEVAHALFSVPTKIARIRDQSYMKPEYADLFSRENMSIDVTISPEVEVGKMVLRRIAFPGATDVVRFAEDTIYMLAIE
CMEDCPVINTPLQQLSSLFPDLIATVVGVYRDGILKVAHSSEQLRVGDLAYVICQRQHARRTLSLFGHEEQEAQRIVIAG
AGNIGHFVAHKIEEMQSKTRVKIIEADRDRAIAASEQLSHTIVMHGSALDQKILMQADIQDADLIVTLTNNDQTNILAAV
IAKQLGCKSNLALLNSTSFHDVARSLGLDAYINPRAVTISRVLQHVRKGRIRSVYAVQRGSAEVIEAEALETSPLVGQSF
RDIDMPDGVRIGAIYRDGVVIRPDGSTKIKAKDRVVLFASADAVRDVEQLFRVSIQYF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=37.117903930131, Blast_Score=290, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 50195; Mature: 50195

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIICGAGQVGYGIAEQLSREDNEVSVIDTAAPLITAITETLDVRGYVGHGAHPDMLAK
CEEEEECCCCCCHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCEEECCCCCHHHHHH
AGADQADMIIAVTLHDEINIVACEVAHALFSVPTKIARIRDQSYMKPEYADLFSRENMSI
CCCCCCCEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEE
DVTISPEVEVGKMVLRRIAFPGATDVVRFAEDTIYMLAIECMEDCPVINTPLQQLSSLFP
EEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHHHHCCCCCCCHHHHHHHHHH
DLIATVVGVYRDGILKVAHSSEQLRVGDLAYVICQRQHARRTLSLFGHEEQEAQRIVIAG
HHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
AGNIGHFVAHKIEEMQSKTRVKIIEADRDRAIAASEQLSHTIVMHGSALDQKILMQADIQ
CCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCEEEEEECCCCCHHHHHHCCCC
DADLIVTLTNNDQTNILAAVIAKQLGCKSNLALLNSTSFHDVARSLGLDAYINPRAVTIS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCEECCCHHHHH
RVLQHVRKGRIRSVYAVQRGSAEVIEAEALETSPLVGQSFRDIDMPDGVRIGAIYRDGVV
HHHHHHHCCCCEEEEEEECCCHHEEEHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCEE
IRPDGSTKIKAKDRVVLFASADAVRDVEQLFRVSIQYF
ECCCCCCEEEECCEEEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVIICGAGQVGYGIAEQLSREDNEVSVIDTAAPLITAITETLDVRGYVGHGAHPDMLAK
CEEEEECCCCCCHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCEEECCCCCHHHHHH
AGADQADMIIAVTLHDEINIVACEVAHALFSVPTKIARIRDQSYMKPEYADLFSRENMSI
CCCCCCCEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEE
DVTISPEVEVGKMVLRRIAFPGATDVVRFAEDTIYMLAIECMEDCPVINTPLQQLSSLFP
EEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEHHHHHHHCCCCCCCHHHHHHHHHH
DLIATVVGVYRDGILKVAHSSEQLRVGDLAYVICQRQHARRTLSLFGHEEQEAQRIVIAG
HHHHHHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
AGNIGHFVAHKIEEMQSKTRVKIIEADRDRAIAASEQLSHTIVMHGSALDQKILMQADIQ
CCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCEEEEEECCCCCHHHHHHCCCC
DADLIVTLTNNDQTNILAAVIAKQLGCKSNLALLNSTSFHDVARSLGLDAYINPRAVTIS
CCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCCCCEECCCHHHHH
RVLQHVRKGRIRSVYAVQRGSAEVIEAEALETSPLVGQSFRDIDMPDGVRIGAIYRDGVV
HHHHHHHCCCCEEEEEEECCCHHEEEHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCEE
IRPDGSTKIKAKDRVVLFASADAVRDVEQLFRVSIQYF
ECCCCCCEEEECCEEEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]