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The map label for this gene is msrB

Identifier: 15888246

GI number: 15888246

Start: 898311

End: 898718

Strand: Reverse

Name: msrB

Synonym: Atu0908

Alternate gene names: 15888246

Gene position: 898718-898311 (Counterclockwise)

Preceding gene: 15888257

Following gene: 159184524

Centisome position: 31.63

GC content: 62.25

Gene sequence:

>408_bases
ATGAGCGATCTGACATCCCCCAAAGTCAACAAGAGCGATGCCGACTGGCGTGAACAGCTGACGCCGGAACAATATCACAT
CCTGCGCGAACACGGCACCGAGCGCCCTTTCACCGGTCCCTACTGGAACTCGACCGAGAAAGGCCTCTACCGCTGCGCCG
CCTGTGACGAGCCGCTGTTCCTCTCCGACACGAAATTCGATGCCGGCTGCGGCTGGCCGAGCTATTTCGAGCCCGTGAAG
CCAGGTGCCGTAACGGAGCATCGCGATTCGACCCACGGCATGGTGCGCACTGAAATCCGCTGCGCCAATTGCGGCGGCCA
TCTCGGCCACGTCTTCCCCGACGGCCCGCCTCCCACCGGCCTGCGTTATTGCATCAACGGCCATTCGATGGTGTTCGAGC
CGGTTTGA

Upstream 100 bases:

>100_bases
ATCGGTACTTTCGCCCCATAACGAACGCGTTATGACGCCTCGCCCCTTTCAATCGGCGGCGGCGATGATTATTTGAGGCG
GGAACAGAAAGGATCATTCC

Downstream 100 bases:

>100_bases
GCGGCAAGACCGTGCCGCGAATTCTTCTCCCCGCCGGGGAGAAGAAACAAGCGGCATAAGCCCGATCCGGAGATGGCGTT
AAGCTTTCAGCCCAGCTTCA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MSDLTSPKVNKSDADWREQLTPEQYHILREHGTERPFTGPYWNSTEKGLYRCAACDEPLFLSDTKFDAGCGWPSYFEPVK
PGAVTEHRDSTHGMVRTEIRCANCGGHLGHVFPDGPPPTGLRYCINGHSMVFEPV

Sequences:

>Translated_135_residues
MSDLTSPKVNKSDADWREQLTPEQYHILREHGTERPFTGPYWNSTEKGLYRCAACDEPLFLSDTKFDAGCGWPSYFEPVK
PGAVTEHRDSTHGMVRTEIRCANCGGHLGHVFPDGPPPTGLRYCINGHSMVFEPV
>Mature_134_residues
SDLTSPKVNKSDADWREQLTPEQYHILREHGTERPFTGPYWNSTEKGLYRCAACDEPLFLSDTKFDAGCGWPSYFEPVKP
GAVTEHRDSTHGMVRTEIRCANCGGHLGHVFPDGPPPTGLRYCINGHSMVFEPV

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI301336164, Length=133, Percent_Identity=47.3684210526316, Blast_Score=139, Evalue=8e-34,
Organism=Homo sapiens, GI301336162, Length=133, Percent_Identity=47.3684210526316, Blast_Score=139, Evalue=8e-34,
Organism=Homo sapiens, GI73089054, Length=133, Percent_Identity=47.3684210526316, Blast_Score=139, Evalue=8e-34,
Organism=Homo sapiens, GI37620216, Length=133, Percent_Identity=47.3684210526316, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI117606353, Length=139, Percent_Identity=42.4460431654676, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=51.2396694214876, Blast_Score=142, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=138, Percent_Identity=48.5507246376812, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=138, Percent_Identity=48.5507246376812, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=128, Percent_Identity=47.65625, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI221378664, Length=131, Percent_Identity=52.6717557251908, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI221378662, Length=138, Percent_Identity=50, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24645799, Length=131, Percent_Identity=51.9083969465649, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI45553335, Length=131, Percent_Identity=51.9083969465649, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21356369, Length=131, Percent_Identity=51.9083969465649, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24645801, Length=142, Percent_Identity=47.1830985915493, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24645804, Length=142, Percent_Identity=47.1830985915493, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_AGRT5 (Q8UGX7)

Other databases:

- EMBL:   AE007869
- PIR:   AD2688
- PIR:   G97469
- RefSeq:   NP_353927.1
- ProteinModelPortal:   Q8UGX7
- SMR:   Q8UGX7
- STRING:   Q8UGX7
- GeneID:   1132946
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu0908
- eggNOG:   COG0229
- HOGENOM:   HBG715255
- OMA:   CINSICL
- PhylomeDB:   Q8UGX7
- ProtClustDB:   PRK00222
- BioCyc:   ATUM176299-1:ATU0908-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 15140; Mature: 15009

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: ACT_SITE 124-124

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLTSPKVNKSDADWREQLTPEQYHILREHGTERPFTGPYWNSTEKGLYRCAACDEPLF
CCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEE
LSDTKFDAGCGWPSYFEPVKPGAVTEHRDSTHGMVRTEIRCANCGGHLGHVFPDGPPPTG
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCC
LRYCINGHSMVFEPV
EEEEECCCEEEEECC
>Mature Secondary Structure 
SDLTSPKVNKSDADWREQLTPEQYHILREHGTERPFTGPYWNSTEKGLYRCAACDEPLF
CCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEE
LSDTKFDAGCGWPSYFEPVKPGAVTEHRDSTHGMVRTEIRCANCGGHLGHVFPDGPPPTG
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCC
LRYCINGHSMVFEPV
EEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194