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The map label for this gene is 15888091

Identifier: 15888091

GI number: 15888091

Start: 746187

End: 747122

Strand: Reverse

Name: 15888091

Synonym: Atu0748

Alternate gene names: NA

Gene position: 747122-746187 (Counterclockwise)

Preceding gene: 159184449

Following gene: 159184448

Centisome position: 26.29

GC content: 59.19

Gene sequence:

>936_bases
ATGGCGACCCGCCTATACGAACATCCGATCTTCCTTGAGCATATCACGCCCGAAGGCCACCCCGAGCGGCCGGACCGTCT
GCGGTCGCTGAACATCGCGCTTGAACATCCGAATTTCGAGCGGCTGGACCGGAAGGAAGCGCCGCAGGCCAATGAGGATG
CGGTGCTTCTGGCGCATCCGGAAGAGCATCTCCTTGCCGTCATGCGACAGGTGCCGGAAGAAGATGGCGAGATCAACCGC
ATCGAGTCCGACACCTATCTCTCCCCGAAAAGCCTGCAGGCGGCGCTGACAGGCATCGGCGCTGCCATGGCAGCGGTGGA
TGACGTGTTTAGCGGTGCGGCCGACAATGTCTTCGTCGCTGCCCGCCCACCCGGCCACCACGCGGAAACCGCCAAGGCCA
TGGGTTTCTGTCTCTTCAACAATGTGGCGATTGCCGCCCGCCATGCGCAAAAGGCGCACGGTGCAGAGCGCATTGCCATC
ATCGACTGGGACGTGCATCACGGCAACGGCACGCAGGATATCTTTTGGAACGACATATCCGTGCTGTTTTGTTCCACACA
TCAGATGCCGCTTTACCCGTGGAGCGGCGATAAAAACGAAACCGGCGTAAAGAACAACATCGTCAACGCGCCGCTTTCGC
CCAATACCGGCAGCGACCATTTTCGCGAAGCGTTCAAATCGCGGGTTCTGCCGGCAATCGCCGATTTTTCGCCTGACCTC
ATCCTCATCTCCGCCGGTTTTGACGCGCATCACCGCGATCCGCTGGCGCAGATCAATCTGGTGGGCGAGGATTTTGACTG
GGCAACCGGCCGGCTTCTGGAAATGGCCGATAAATACGCCTCCAACCGGGTCGTCAGCCTGCTGGAAGGTGGTTATGATC
TGGAAGGGCTGGCGGAATCGGCAGCCATGCATATTTTGAGAATGATGAAGGGTTGA

Upstream 100 bases:

>100_bases
CTGAAGGCCGTTCTTGCCGCACTGGCCGGCCGCGCCGTCATGGCCGGTTATCCGCTGCTGCCGCAGCGCGCCTGATCGAG
CTTTCTCCGGGAGGACAAGA

Downstream 100 bases:

>100_bases
ACATGACGGAAAATGCCAACACAGCCGATGTCAGCGGTTATTCTTTCGAAAAAGCCGTCGCCGAGCTGGAAAGCATTGTC
GCACGTCTGGAACGCGGCGA

Product: deacetylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MATRLYEHPIFLEHITPEGHPERPDRLRSLNIALEHPNFERLDRKEAPQANEDAVLLAHPEEHLLAVMRQVPEEDGEINR
IESDTYLSPKSLQAALTGIGAAMAAVDDVFSGAADNVFVAARPPGHHAETAKAMGFCLFNNVAIAARHAQKAHGAERIAI
IDWDVHHGNGTQDIFWNDISVLFCSTHQMPLYPWSGDKNETGVKNNIVNAPLSPNTGSDHFREAFKSRVLPAIADFSPDL
ILISAGFDAHHRDPLAQINLVGEDFDWATGRLLEMADKYASNRVVSLLEGGYDLEGLAESAAMHILRMMKG

Sequences:

>Translated_311_residues
MATRLYEHPIFLEHITPEGHPERPDRLRSLNIALEHPNFERLDRKEAPQANEDAVLLAHPEEHLLAVMRQVPEEDGEINR
IESDTYLSPKSLQAALTGIGAAMAAVDDVFSGAADNVFVAARPPGHHAETAKAMGFCLFNNVAIAARHAQKAHGAERIAI
IDWDVHHGNGTQDIFWNDISVLFCSTHQMPLYPWSGDKNETGVKNNIVNAPLSPNTGSDHFREAFKSRVLPAIADFSPDL
ILISAGFDAHHRDPLAQINLVGEDFDWATGRLLEMADKYASNRVVSLLEGGYDLEGLAESAAMHILRMMKG
>Mature_310_residues
ATRLYEHPIFLEHITPEGHPERPDRLRSLNIALEHPNFERLDRKEAPQANEDAVLLAHPEEHLLAVMRQVPEEDGEINRI
ESDTYLSPKSLQAALTGIGAAMAAVDDVFSGAADNVFVAARPPGHHAETAKAMGFCLFNNVAIAARHAQKAHGAERIAII
DWDVHHGNGTQDIFWNDISVLFCSTHQMPLYPWSGDKNETGVKNNIVNAPLSPNTGSDHFREAFKSRVLPAIADFSPDLI
LISAGFDAHHRDPLAQINLVGEDFDWATGRLLEMADKYASNRVVSLLEGGYDLEGLAESAAMHILRMMKG

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=306, Percent_Identity=36.6013071895425, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI13128864, Length=299, Percent_Identity=37.4581939799331, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI153085395, Length=220, Percent_Identity=39.0909090909091, Blast_Score=161, Evalue=6e-40,
Organism=Homo sapiens, GI30795204, Length=339, Percent_Identity=32.7433628318584, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI17158039, Length=339, Percent_Identity=32.7433628318584, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI30795202, Length=339, Percent_Identity=32.7433628318584, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI169234807, Length=216, Percent_Identity=41.2037037037037, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI148539870, Length=216, Percent_Identity=41.2037037037037, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI62750349, Length=316, Percent_Identity=33.2278481012658, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI62750347, Length=316, Percent_Identity=33.2278481012658, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI226529806, Length=306, Percent_Identity=33.0065359477124, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI13128860, Length=257, Percent_Identity=24.124513618677, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI293336691, Length=257, Percent_Identity=23.3463035019455, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI13128862, Length=256, Percent_Identity=23.828125, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI8923769, Length=180, Percent_Identity=25, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=302, Percent_Identity=36.7549668874172, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193206283, Length=302, Percent_Identity=36.7549668874172, Blast_Score=188, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17540332, Length=302, Percent_Identity=36.7549668874172, Blast_Score=188, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI193209491, Length=320, Percent_Identity=35.9375, Blast_Score=170, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI25154020, Length=292, Percent_Identity=28.4246575342466, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25154022, Length=293, Percent_Identity=28.3276450511945, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17537347, Length=312, Percent_Identity=31.0897435897436, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534739, Length=302, Percent_Identity=25.8278145695364, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508561, Length=296, Percent_Identity=23.3108108108108, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561978, Length=258, Percent_Identity=24.4186046511628, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=320, Percent_Identity=32.5, Blast_Score=149, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6325141, Length=285, Percent_Identity=28.7719298245614, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6321244, Length=256, Percent_Identity=27.734375, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323999, Length=255, Percent_Identity=24.7058823529412, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325325, Length=185, Percent_Identity=27.027027027027, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360899, Length=298, Percent_Identity=35.5704697986577, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI24642146, Length=298, Percent_Identity=35.5704697986577, Blast_Score=177, Evalue=8e-45,
Organism=Drosophila melanogaster, GI24642142, Length=298, Percent_Identity=35.5704697986577, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24642144, Length=298, Percent_Identity=35.5704697986577, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24641720, Length=340, Percent_Identity=32.6470588235294, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281360799, Length=340, Percent_Identity=32.6470588235294, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281360801, Length=340, Percent_Identity=32.6470588235294, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24657891, Length=274, Percent_Identity=25.1824817518248, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644244, Length=268, Percent_Identity=26.1194029850746, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24649807, Length=257, Percent_Identity=25.2918287937743, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 34285; Mature: 34154

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRLYEHPIFLEHITPEGHPERPDRLRSLNIALEHPNFERLDRKEAPQANEDAVLLAHP
CCCCCCCCCEEEEECCCCCCCCCCHHHEEEEEEEECCCHHHHHHHCCCCCCCCEEEEECC
EEHLLAVMRQVPEEDGEINRIESDTYLSPKSLQAALTGIGAAMAAVDDVFSGAADNVFVA
HHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
ARPPGHHAETAKAMGFCLFNNVAIAARHAQKAHGAERIAIIDWDVHHGNGTQDIFWNDIS
ECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEECCEE
VLFCSTHQMPLYPWSGDKNETGVKNNIVNAPLSPNTGSDHFREAFKSRVLPAIADFSPDL
EEEEECCCCEEECCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCE
ILISAGFDAHHRDPLAQINLVGEDFDWATGRLLEMADKYASNRVVSLLEGGYDLEGLAES
EEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AAMHILRMMKG
HHHHHHHHHCC
>Mature Secondary Structure 
ATRLYEHPIFLEHITPEGHPERPDRLRSLNIALEHPNFERLDRKEAPQANEDAVLLAHP
CCCCCCCCEEEEECCCCCCCCCCHHHEEEEEEEECCCHHHHHHHCCCCCCCCEEEEECC
EEHLLAVMRQVPEEDGEINRIESDTYLSPKSLQAALTGIGAAMAAVDDVFSGAADNVFVA
HHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
ARPPGHHAETAKAMGFCLFNNVAIAARHAQKAHGAERIAIIDWDVHHGNGTQDIFWNDIS
ECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCEEECCEE
VLFCSTHQMPLYPWSGDKNETGVKNNIVNAPLSPNTGSDHFREAFKSRVLPAIADFSPDL
EEEEECCCCEEECCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCHHHHCCCCCE
ILISAGFDAHHRDPLAQINLVGEDFDWATGRLLEMADKYASNRVVSLLEGGYDLEGLAES
EEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AAMHILRMMKG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]