Click here to switch to the map view.

The map label for this gene is rcsC [H]

Identifier: 15888044

GI number: 15888044

Start: 699319

End: 700986

Strand: Direct

Name: rcsC [H]

Synonym: Atu0700

Alternate gene names: 15888044

Gene position: 699319-700986 (Clockwise)

Preceding gene: 15888041

Following gene: 15888045

Centisome position: 24.61

GC content: 60.67

Gene sequence:

>1668_bases
TTGCAGTTGAGTGATTTGGCGTCCTCTGGCGCGGGCGTTCATACGGTGATGCTTGATGCCCTTTGCGACGCGCTTGGCGC
GGCGATCGTCGTTTACGACCGAAACGATCACATTATTTTCGCAAGCCGGAAACTCCTGAGCTTTTTCCCGCTGGAAGAGG
CCGTCGCCAGTCCGGGCGCGCGCCTGCGCGACTATCTGAGCGCGCTTTACGATTGTTATCTGCTGGAGGCGGAAAGTCTC
TCCAGCAATGCCCGCCAGCTCGGCCGGGAGGAATGGATCGGCGAGCGGCTGGCGCTGCACTGGAAGGAACGGTCGGAAAA
GACCGAGCGGCTGAAGGGAGAGCGCTTCCTGCGCTTCGTCATGAACCGTCTGCCGTCTGGTCTCGGCATCAGCGTGGTTG
CCGATATTTCCGAACAGAAGAAACGCGAAGAGCAATGGCGCCTCGACCTCGAGCGTGTCCAGCTCATTGAGGACATTCTC
GACAATCTGCCGTTTCCGGTTCTCGTCAAGGATCGAAACCTCGCTTATGCGGCCGTCAACAAAGCCGCCTGCACCATGGT
TGAAACCAGCGCCGAGAGCATTCTCGGCCGCACCGTTTTTGATCTGCATTCGCGCAAGGTCGCCCGCCGGATCGATGCCG
CGGACCGCATGGTCCTGGATAGCGGCACGCCGAGCATCATTCCTGAAAGAGTGAGACGCCTGAATGGCGAAGAGGTTCTG
ACGATCACCCGCAAGCAGCGCGTGGGCAGGCCCGGCCGATATTTTCTGGTAACGACGATGGAGGACGTGACCGCTCTCGC
CACCATCGATGCGAACGGCATGCCTGTCATCCCCTCGCTCGAACATGTTCCCTTCGTGGCCTCCACCTATGGCAAGGATG
AGGAAACGGACGGCCGCAGCGGGCTTTTGAAGAGCAAGGCGGTGCTGATCGTCTCCGAAAACACACGTTTTGCGGAGGCC
GCCGGCCAGCGGCTGGCTGCCGGCGGCATGGATCATGCGGCGGTGATGAGCGAGGACGAACAGCGCGCCTTCATCGATGT
CGCTGCCTCCGCCGGTGTGGGCATCGACGTGGTCGTCGTCGACGCCCAGATGAGCGTCGCATGCCTTGATATTGCCGCCG
CCCACGGCCTGCCCGTCGTCACCATCGAGGAAGAGGAGATCGATGCATCGCTCATGCATTATCTCGCCGTCGGGCTGAAA
TCCTCACCGAAGGAGAAAGCCGAGGACGAGGACTGGGAGATCATGACCGACGACCTGCCGGAAATGCTCAGAACCGGCAG
CGTCTGCGATATCCTTCTCGTTGAGGACAACAGGGTCAACCAGATCGTCTTTTCGCAAATCCTCGAGGGGCTGGGACTTT
CCTGGCGGCTCGCCACCTCCGGCGAGGAGGCCTTGCGCCTTTTTGTCGAACAGTCGCCATCCGTCGTCCTTCTCGATACG
ACGCTCGGGGATATCGACGGTTTCGAGGTCGCCCAACGCATGCGCGATCTCGCCGGCGACAAACATATTCCCATCGTCGG
TGTCATCACCCATGCCTTCGAGGGCGATCTCGACAAATGCCTGGCGTCCGGCATGGACGACATGCTGCTGAAACCCGTAA
GCCCTGACATGGTCGAGGCGGTTTTCCTGCGGCTTATCGGCAAGGATGTCCTGCGGCTGCAGGCCTGA

Upstream 100 bases:

>100_bases
CCCTGATGTCTCTTTTTCGGAATTTGTCGTTTCATCCCGGCATCTGCCCTGGACGATTCCAATAGAAACATAAGCCTGAT
CCAGAAAAACAGGTGGGAGT

Downstream 100 bases:

>100_bases
AATTTCCATTGTCGGGAGGCTATGGCTTTTTTAATACTTGCCCTGCATTGTGAGCGCGGTCGACACAGGATTCACGAGAT
GCAGGAATGAAACGGGCAGA

Product: two component sensor kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MQLSDLASSGAGVHTVMLDALCDALGAAIVVYDRNDHIIFASRKLLSFFPLEEAVASPGARLRDYLSALYDCYLLEAESL
SSNARQLGREEWIGERLALHWKERSEKTERLKGERFLRFVMNRLPSGLGISVVADISEQKKREEQWRLDLERVQLIEDIL
DNLPFPVLVKDRNLAYAAVNKAACTMVETSAESILGRTVFDLHSRKVARRIDAADRMVLDSGTPSIIPERVRRLNGEEVL
TITRKQRVGRPGRYFLVTTMEDVTALATIDANGMPVIPSLEHVPFVASTYGKDEETDGRSGLLKSKAVLIVSENTRFAEA
AGQRLAAGGMDHAAVMSEDEQRAFIDVAASAGVGIDVVVVDAQMSVACLDIAAAHGLPVVTIEEEEIDASLMHYLAVGLK
SSPKEKAEDEDWEIMTDDLPEMLRTGSVCDILLVEDNRVNQIVFSQILEGLGLSWRLATSGEEALRLFVEQSPSVVLLDT
TLGDIDGFEVAQRMRDLAGDKHIPIVGVITHAFEGDLDKCLASGMDDMLLKPVSPDMVEAVFLRLIGKDVLRLQA

Sequences:

>Translated_555_residues
MQLSDLASSGAGVHTVMLDALCDALGAAIVVYDRNDHIIFASRKLLSFFPLEEAVASPGARLRDYLSALYDCYLLEAESL
SSNARQLGREEWIGERLALHWKERSEKTERLKGERFLRFVMNRLPSGLGISVVADISEQKKREEQWRLDLERVQLIEDIL
DNLPFPVLVKDRNLAYAAVNKAACTMVETSAESILGRTVFDLHSRKVARRIDAADRMVLDSGTPSIIPERVRRLNGEEVL
TITRKQRVGRPGRYFLVTTMEDVTALATIDANGMPVIPSLEHVPFVASTYGKDEETDGRSGLLKSKAVLIVSENTRFAEA
AGQRLAAGGMDHAAVMSEDEQRAFIDVAASAGVGIDVVVVDAQMSVACLDIAAAHGLPVVTIEEEEIDASLMHYLAVGLK
SSPKEKAEDEDWEIMTDDLPEMLRTGSVCDILLVEDNRVNQIVFSQILEGLGLSWRLATSGEEALRLFVEQSPSVVLLDT
TLGDIDGFEVAQRMRDLAGDKHIPIVGVITHAFEGDLDKCLASGMDDMLLKPVSPDMVEAVFLRLIGKDVLRLQA
>Mature_555_residues
MQLSDLASSGAGVHTVMLDALCDALGAAIVVYDRNDHIIFASRKLLSFFPLEEAVASPGARLRDYLSALYDCYLLEAESL
SSNARQLGREEWIGERLALHWKERSEKTERLKGERFLRFVMNRLPSGLGISVVADISEQKKREEQWRLDLERVQLIEDIL
DNLPFPVLVKDRNLAYAAVNKAACTMVETSAESILGRTVFDLHSRKVARRIDAADRMVLDSGTPSIIPERVRRLNGEEVL
TITRKQRVGRPGRYFLVTTMEDVTALATIDANGMPVIPSLEHVPFVASTYGKDEETDGRSGLLKSKAVLIVSENTRFAEA
AGQRLAAGGMDHAAVMSEDEQRAFIDVAASAGVGIDVVVVDAQMSVACLDIAAAHGLPVVTIEEEEIDASLMHYLAVGLK
SSPKEKAEDEDWEIMTDDLPEMLRTGSVCDILLVEDNRVNQIVFSQILEGLGLSWRLATSGEEALRLFVEQSPSVVLLDT
TLGDIDGFEVAQRMRDLAGDKHIPIVGVITHAFEGDLDKCLASGMDDMLLKPVSPDMVEAVFLRLIGKDVLRLQA

Specific function: Member of the two-component regulatory system rcsC/rcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with rcsF, rcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=109, Percent_Identity=33.0275229357798, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61042; Mature: 61042

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSDLASSGAGVHTVMLDALCDALGAAIVVYDRNDHIIFASRKLLSFFPLEEAVASPGA
CCCHHHHCCCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEECHHHHHHCCHHHHHHCCCH
RLRDYLSALYDCYLLEAESLSSNARQLGREEWIGERLALHWKERSEKTERLKGERFLRFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNRLPSGLGISVVADISEQKKREEQWRLDLERVQLIEDILDNLPFPVLVKDRNLAYAAVN
HHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEHHH
KAACTMVETSAESILGRTVFDLHSRKVARRIDAADRMVLDSGTPSIIPERVRRLNGEEVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHCCCCEEE
TITRKQRVGRPGRYFLVTTMEDVTALATIDANGMPVIPSLEHVPFVASTYGKDEETDGRS
EEEHHHHCCCCCCEEEEEEHHHHEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCC
GLLKSKAVLIVSENTRFAEAAGQRLAAGGMDHAAVMSEDEQRAFIDVAASAGVGIDVVVV
CCCCCCEEEEEECCCCHHHHHCCHHHCCCCCCHHHCCCCCHHHEEEEHHCCCCCEEEEEE
DAQMSVACLDIAAAHGLPVVTIEEEEIDASLMHYLAVGLKSSPKEKAEDEDWEIMTDDLP
ECCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHH
EMLRTGSVCDILLVEDNRVNQIVFSQILEGLGLSWRLATSGEEALRLFVEQSPSVVLLDT
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEEEC
TLGDIDGFEVAQRMRDLAGDKHIPIVGVITHAFEGDLDKCLASGMDDMLLKPVSPDMVEA
CCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHCCCHHHHCCCCCHHHHHH
VFLRLIGKDVLRLQA
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MQLSDLASSGAGVHTVMLDALCDALGAAIVVYDRNDHIIFASRKLLSFFPLEEAVASPGA
CCCHHHHCCCCCHHHHHHHHHHHHHCCEEEEEECCCCEEEECHHHHHHCCHHHHHHCCCH
RLRDYLSALYDCYLLEAESLSSNARQLGREEWIGERLALHWKERSEKTERLKGERFLRFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNRLPSGLGISVVADISEQKKREEQWRLDLERVQLIEDILDNLPFPVLVKDRNLAYAAVN
HHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEHHH
KAACTMVETSAESILGRTVFDLHSRKVARRIDAADRMVLDSGTPSIIPERVRRLNGEEVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHCCCCEEE
TITRKQRVGRPGRYFLVTTMEDVTALATIDANGMPVIPSLEHVPFVASTYGKDEETDGRS
EEEHHHHCCCCCCEEEEEEHHHHEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCC
GLLKSKAVLIVSENTRFAEAAGQRLAAGGMDHAAVMSEDEQRAFIDVAASAGVGIDVVVV
CCCCCCEEEEEECCCCHHHHHCCHHHCCCCCCHHHCCCCCHHHEEEEHHCCCCCEEEEEE
DAQMSVACLDIAAAHGLPVVTIEEEEIDASLMHYLAVGLKSSPKEKAEDEDWEIMTDDLP
ECCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHH
EMLRTGSVCDILLVEDNRVNQIVFSQILEGLGLSWRLATSGEEALRLFVEQSPSVVLLDT
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCEEEEEC
TLGDIDGFEVAQRMRDLAGDKHIPIVGVITHAFEGDLDKCLASGMDDMLLKPVSPDMVEA
CCCCCCHHHHHHHHHHHCCCCCCCEEEEEHHHHCCCHHHHHHCCCHHHHCCCCCHHHHHH
VFLRLIGKDVLRLQA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504; 8626298 [H]