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The map label for this gene is pdhS [H]

Identifier: 15887959

GI number: 15887959

Start: 602711

End: 606538

Strand: Reverse

Name: pdhS [H]

Synonym: Atu0614

Alternate gene names: 15887959

Gene position: 606538-602711 (Counterclockwise)

Preceding gene: 159184391

Following gene: 159184389

Centisome position: 21.35

GC content: 60.89

Gene sequence:

>3828_bases
ATGCCCGCCGTCCAATATCCCTTTATCGATATAGCAGTGCATGAACGGGTGCGCGAAGGTTTTGGGCGCGGCGAGGCCAT
GGCGCTGTTTTCGCTCGATCTTCAGAATGTGCTCTGGGCCAATGGGCGCGGCGCGGCGCTGTTCGGCACGCCGATCGTTT
ACGATTTTCTGGAGCAGGGTCCCAAACGGCAGGATGTGACCTTCCGGCAATTGGCGGCCACGGCGGCCCGGCTTTCGAAA
GCCGGCGACAGCCTGCCGTTTACCATTCGCATCACTTCGGGTTTCCGCAGCCTTGCCGTCACCGCCCGCGCGGAGATCAT
CGAGGCGGAACCCGGCCACCCGGCTATCCTGTTTTCCGCCCTCACCGATCAGGCAGCGCCCGACGTGGCCGAATGCGCCC
GGCGCATGATCGAAGGGTTTGACGATCCGGATATTCATATGGCGGTGCTGAATGGCGACAATGAGATCATTGCCGCCTCG
TCAGGCTTTTCGTCGCTCGGCATCACGCCGCATACCGCGCGCACGCTCATCAAAATGGCCGCCGGCCAGTCCGGTCATCT
CGTCAAACGCCCGGTTCCAACCGGCAAGGGTTATCTGCCCGCCGCCACCGGCCAGATCACGACATCGCCCGAACTGAACC
TGCTGTTCGTGGTGGAAACCGCGCTCGGGACGCTCGATCCCGTCAATGGTTTTGCCGAAGACAGGGGGTTTTCCGAAGAT
AGGGATGTTGCCGAAGACAGAAATGTTGCCGAAAGCAGGCCGCAGGAAATCCCGGCGGCCGCCGAGCCTGCCCTGCCGAT
AGCGGAGGCGGCACCCGTTATCGCAGCAACCACCTCTTTCGATTCCGTGCTCGACGCCGTTGCCGGCATAGAGGATGTGG
AGGATATTCAGGAACTGCCGTCCGATTTCGAAGAGGACGTGGCAGCCGAACAGGATGAAGACGGCCTTCTGTCAATGCCT
GACGACAAGGTGGAGACACCGGCAGAGCCTCCCGTGTTGGATGCTGACGCCGCCGCCGATATGGCGATGACCGACGACAT
TGAGGACCTCTTCGAACTCGACGCTGATGAAACGGTGGCTCCCTCGATCGAGCGAACGGTCACGGAGGATCATACGCTAG
AGGCACAGGCCGAGGAAAACACTTTCGCGGACGATGAAATCGCTGAAACGGAGGCGGAAGAAGCTACTACTGCGGCGGAC
GACGAGCTAACGACGGAGACGGAAACGGCAAACATCGGCACTGGCGAAGAAGCACGGCCTTTTGTCTTTAATGCCGGTGC
ACGCGCCTCACGTTTCGTCTGGAAAATCGACGCCGAAGGGCGTTTCAGCTCGATTTCGCACGAATTTGCAGAAGCCGTGG
GCGCCAAGGCGGCCGCCGTGGAAGGCATGGGCTTTGCCGATGTCGCGGCCCTGTTCAATCTCGATCCCGACGGCAAGATC
CGCGAGCTTCTCGGCCGGCGCGACACCTGGTCGGGCAAGACGATCTACTGGCCGGTGGAAGGCACCTCGTTGATGGTGCC
GATCGATCTCGCCGCCCTGCCGACCTATACGCGTGCCCGCGAATTTGACGGTTTCCGCGGTTTCGGCATCGTGCGCCTCG
CCGATGCCACCGAAGACCCACATGCCACCGGGCTGACCTTCCTGAATAGTGAAGAGACGGAGCCCGCAGAGGTTTTGCCG
CAGCAGGCCGTCGAAGATGAAAGCCATGAATTGCTGGCTTTTGTCGATGAAGACACGGAAACGGACGACAATCCTCACCC
AGCGCTGCCTGATGAACCGGCGGTAGACATCGATATTGCAGGCGATGCAGCAGACGGGGTTTTGACGGAAGAACAGCTTG
ATGATGAGACCTCACCGGAAGTCGAATCGCCAATAGAAGCGCCAGCGCCCGAACCCTCCTATTCCGACAAGGTCGTGCAT
CTGGAGGACCGCCGTTCGCGCTCCCGCGAGGGACTGACCGCAGGCGAACAGGCAGCCTTCCGCGAGATCGGCCGGGCGCT
TGCGCCATCCGATATGGCGTCGGAGGAAAAACACGAGGCGGATGCCGAAGGGATTTCGGCCGAGCCGGTCGTTCAGGATA
TCCAGCAAGACATCGCGGCGGAGACCGCAAAAGACGCGTCCTCCGACACTGGCAACGACGCAGAGACAACTGAACCGGTG
GAAGAAGACGATCTTTTTGCCGATTATGTTCGCGGTGAACAGCCAGCGCCCGTTCGTGCACCCACCGATGAACCCACTTC
TGCAGAAAAGCAGGTGGTCACCACCGACGAGAAGCCGGTTGCTGACATTGCCGCCTCCATGGTCAGCCCGCCCGTTCGCA
CCCCCAGTGCGCTGACGGCCGAGACGCTGGATCAGATGCCTGTGGCGCTTCTGGTCCATGCCGGGGACAGGCTGATCCAC
GCCAATCCCGATTTCCTGCGACTGACGGGCTATACCTCTCTGACTGAACTGGAAGAGGTGGGCGGGCTGGAAGCACTGCT
GCAGCGGCAGGAGCTGGAGAACATGCCTGACAATGAGGGCGGCATGGTCGTCGTCAGCGCTGAAAATGACATCATTCCGG
TCAAGGCGCGGCTGCAATCCATCCGCTGGGAAGAAACGAAGGCGCTGATGCTGTCGCTGGTTCCGCTGGAAGAAAAGCCG
GCGGCGGTTATGGCGGCCAATGAAAACACCGCGGAAAATGCCGAGGCAGGCAGCAACCTCTCCCTGTTGCAGGGCGAAAT
GGAAGAGCTGCATTCCATCCTGGAAACAGCCACCGATGGTGTGGTGCTTCTGGGCGACGACGGCGAAATCCGCTCGCTCA
ACCGTTCCGCCAGCGCGCTGTTCAATTATGATAATGGCGAAATCGCCGGCAAGCCCTTCGTGACGCTCTTTGCCCATGAG
AGCCAGCGCGCCGTGCTGGATTATCTCTCCGGCCTTGCCAATAATGGTGTCGCCAGCGTGCTGAATGACGGCCGCGAAGT
GATCGGCCGCGAGGCCTCCGGCGGTTTCCTGCCGTTATTCATGACCATTGGACGGCTGAAATCCTCGCACGGCTATTGCG
CCGTGATCCGCGACATCACCCAATGGAAGCGCACCGAAGAAGAGTTGCGCAACGCCAAGCGCGCGGCGGAAACCGCCAAT
GCACACAAGACGGACTTTCTGGCCCGCGTCAGCCACGAAATCCGCACGCCGCTCAACGCCATCATCGGTTTCTCCGACAT
GATGGCGACCGAACGTTTCGGGCCGATCGGCAATCCGCGTTATGTGGAATATGCCAATGATATCGGCCGTTCCGGCCGGC
ATGTGCTCGATATCGTCAATGATCTCCTCGATATTTCCAAGATCGAGGCCGGGCAGATGGATGTGGATTTTATCGCCGTG
CCGCTGAACGAGACGGTGGCCGAGGCGGTCTCGCTGGTGCAGCCGCAGGCCAACAATCAGCGCGTCATCATTCGCACCGC
GCTGGCACAATCCGTGCCGCAGATCGTCGCCGACCTGCGCTCGATCAAGCAGATCGTGCTGAACATCCTGTCGAACGCCA
TCCGTTTCACCCCATCCGGCGGCCAGATCGTTGTCTCCACCGCCTATGAAGCCAATGGCAGCGTGTCGCTGCGCATCCGC
GACACCGGCATCGGCATGACGCGGGCGGAACTGGAACAGGCGATGAAGCCGTTCCGGCAGGTGGCATCGTCAGGCAAGCG
CGTGCGCGGTGACGGCACCGGGCTTGGCCTGCCGCTGACGAAAGCCATGGTCGACGCCAACCGAGCGAATTTCTCCATCA
CCTCCACGCCGAATGAAGGCACGCTGGTGGAAATCACCTTTCCATCGCAGCGGGTTCTTGCCAACTAA

Upstream 100 bases:

>100_bases
AAAATTCTGTTAACGTGATGCCTGGCGGGTTTACGTTTGGCGGCTTCATGAGGAAGCCGAGGAGCCCGCAAGGTCCGGTA
GTGCCAGAATAGGTTTCGAC

Downstream 100 bases:

>100_bases
GGCCATGCGGGCGTAGCAATGCGACGGTAGGAAGCGGGTGGTTTTCCGAAGATACCATCTCTCCCTCATTCCTGTGCTCG
TCACAGGAATCTAGCCAGCC

Product: two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1275; Mature: 1274

Protein sequence:

>1275_residues
MPAVQYPFIDIAVHERVREGFGRGEAMALFSLDLQNVLWANGRGAALFGTPIVYDFLEQGPKRQDVTFRQLAATAARLSK
AGDSLPFTIRITSGFRSLAVTARAEIIEAEPGHPAILFSALTDQAAPDVAECARRMIEGFDDPDIHMAVLNGDNEIIAAS
SGFSSLGITPHTARTLIKMAAGQSGHLVKRPVPTGKGYLPAATGQITTSPELNLLFVVETALGTLDPVNGFAEDRGFSED
RDVAEDRNVAESRPQEIPAAAEPALPIAEAAPVIAATTSFDSVLDAVAGIEDVEDIQELPSDFEEDVAAEQDEDGLLSMP
DDKVETPAEPPVLDADAAADMAMTDDIEDLFELDADETVAPSIERTVTEDHTLEAQAEENTFADDEIAETEAEEATTAAD
DELTTETETANIGTGEEARPFVFNAGARASRFVWKIDAEGRFSSISHEFAEAVGAKAAAVEGMGFADVAALFNLDPDGKI
RELLGRRDTWSGKTIYWPVEGTSLMVPIDLAALPTYTRAREFDGFRGFGIVRLADATEDPHATGLTFLNSEETEPAEVLP
QQAVEDESHELLAFVDEDTETDDNPHPALPDEPAVDIDIAGDAADGVLTEEQLDDETSPEVESPIEAPAPEPSYSDKVVH
LEDRRSRSREGLTAGEQAAFREIGRALAPSDMASEEKHEADAEGISAEPVVQDIQQDIAAETAKDASSDTGNDAETTEPV
EEDDLFADYVRGEQPAPVRAPTDEPTSAEKQVVTTDEKPVADIAASMVSPPVRTPSALTAETLDQMPVALLVHAGDRLIH
ANPDFLRLTGYTSLTELEEVGGLEALLQRQELENMPDNEGGMVVVSAENDIIPVKARLQSIRWEETKALMLSLVPLEEKP
AAVMAANENTAENAEAGSNLSLLQGEMEELHSILETATDGVVLLGDDGEIRSLNRSASALFNYDNGEIAGKPFVTLFAHE
SQRAVLDYLSGLANNGVASVLNDGREVIGREASGGFLPLFMTIGRLKSSHGYCAVIRDITQWKRTEEELRNAKRAAETAN
AHKTDFLARVSHEIRTPLNAIIGFSDMMATERFGPIGNPRYVEYANDIGRSGRHVLDIVNDLLDISKIEAGQMDVDFIAV
PLNETVAEAVSLVQPQANNQRVIIRTALAQSVPQIVADLRSIKQIVLNILSNAIRFTPSGGQIVVSTAYEANGSVSLRIR
DTGIGMTRAELEQAMKPFRQVASSGKRVRGDGTGLGLPLTKAMVDANRANFSITSTPNEGTLVEITFPSQRVLAN

Sequences:

>Translated_1275_residues
MPAVQYPFIDIAVHERVREGFGRGEAMALFSLDLQNVLWANGRGAALFGTPIVYDFLEQGPKRQDVTFRQLAATAARLSK
AGDSLPFTIRITSGFRSLAVTARAEIIEAEPGHPAILFSALTDQAAPDVAECARRMIEGFDDPDIHMAVLNGDNEIIAAS
SGFSSLGITPHTARTLIKMAAGQSGHLVKRPVPTGKGYLPAATGQITTSPELNLLFVVETALGTLDPVNGFAEDRGFSED
RDVAEDRNVAESRPQEIPAAAEPALPIAEAAPVIAATTSFDSVLDAVAGIEDVEDIQELPSDFEEDVAAEQDEDGLLSMP
DDKVETPAEPPVLDADAAADMAMTDDIEDLFELDADETVAPSIERTVTEDHTLEAQAEENTFADDEIAETEAEEATTAAD
DELTTETETANIGTGEEARPFVFNAGARASRFVWKIDAEGRFSSISHEFAEAVGAKAAAVEGMGFADVAALFNLDPDGKI
RELLGRRDTWSGKTIYWPVEGTSLMVPIDLAALPTYTRAREFDGFRGFGIVRLADATEDPHATGLTFLNSEETEPAEVLP
QQAVEDESHELLAFVDEDTETDDNPHPALPDEPAVDIDIAGDAADGVLTEEQLDDETSPEVESPIEAPAPEPSYSDKVVH
LEDRRSRSREGLTAGEQAAFREIGRALAPSDMASEEKHEADAEGISAEPVVQDIQQDIAAETAKDASSDTGNDAETTEPV
EEDDLFADYVRGEQPAPVRAPTDEPTSAEKQVVTTDEKPVADIAASMVSPPVRTPSALTAETLDQMPVALLVHAGDRLIH
ANPDFLRLTGYTSLTELEEVGGLEALLQRQELENMPDNEGGMVVVSAENDIIPVKARLQSIRWEETKALMLSLVPLEEKP
AAVMAANENTAENAEAGSNLSLLQGEMEELHSILETATDGVVLLGDDGEIRSLNRSASALFNYDNGEIAGKPFVTLFAHE
SQRAVLDYLSGLANNGVASVLNDGREVIGREASGGFLPLFMTIGRLKSSHGYCAVIRDITQWKRTEEELRNAKRAAETAN
AHKTDFLARVSHEIRTPLNAIIGFSDMMATERFGPIGNPRYVEYANDIGRSGRHVLDIVNDLLDISKIEAGQMDVDFIAV
PLNETVAEAVSLVQPQANNQRVIIRTALAQSVPQIVADLRSIKQIVLNILSNAIRFTPSGGQIVVSTAYEANGSVSLRIR
DTGIGMTRAELEQAMKPFRQVASSGKRVRGDGTGLGLPLTKAMVDANRANFSITSTPNEGTLVEITFPSQRVLAN
>Mature_1274_residues
PAVQYPFIDIAVHERVREGFGRGEAMALFSLDLQNVLWANGRGAALFGTPIVYDFLEQGPKRQDVTFRQLAATAARLSKA
GDSLPFTIRITSGFRSLAVTARAEIIEAEPGHPAILFSALTDQAAPDVAECARRMIEGFDDPDIHMAVLNGDNEIIAASS
GFSSLGITPHTARTLIKMAAGQSGHLVKRPVPTGKGYLPAATGQITTSPELNLLFVVETALGTLDPVNGFAEDRGFSEDR
DVAEDRNVAESRPQEIPAAAEPALPIAEAAPVIAATTSFDSVLDAVAGIEDVEDIQELPSDFEEDVAAEQDEDGLLSMPD
DKVETPAEPPVLDADAAADMAMTDDIEDLFELDADETVAPSIERTVTEDHTLEAQAEENTFADDEIAETEAEEATTAADD
ELTTETETANIGTGEEARPFVFNAGARASRFVWKIDAEGRFSSISHEFAEAVGAKAAAVEGMGFADVAALFNLDPDGKIR
ELLGRRDTWSGKTIYWPVEGTSLMVPIDLAALPTYTRAREFDGFRGFGIVRLADATEDPHATGLTFLNSEETEPAEVLPQ
QAVEDESHELLAFVDEDTETDDNPHPALPDEPAVDIDIAGDAADGVLTEEQLDDETSPEVESPIEAPAPEPSYSDKVVHL
EDRRSRSREGLTAGEQAAFREIGRALAPSDMASEEKHEADAEGISAEPVVQDIQQDIAAETAKDASSDTGNDAETTEPVE
EDDLFADYVRGEQPAPVRAPTDEPTSAEKQVVTTDEKPVADIAASMVSPPVRTPSALTAETLDQMPVALLVHAGDRLIHA
NPDFLRLTGYTSLTELEEVGGLEALLQRQELENMPDNEGGMVVVSAENDIIPVKARLQSIRWEETKALMLSLVPLEEKPA
AVMAANENTAENAEAGSNLSLLQGEMEELHSILETATDGVVLLGDDGEIRSLNRSASALFNYDNGEIAGKPFVTLFAHES
QRAVLDYLSGLANNGVASVLNDGREVIGREASGGFLPLFMTIGRLKSSHGYCAVIRDITQWKRTEEELRNAKRAAETANA
HKTDFLARVSHEIRTPLNAIIGFSDMMATERFGPIGNPRYVEYANDIGRSGRHVLDIVNDLLDISKIEAGQMDVDFIAVP
LNETVAEAVSLVQPQANNQRVIIRTALAQSVPQIVADLRSIKQIVLNILSNAIRFTPSGGQIVVSTAYEANGSVSLRIRD
TGIGMTRAELEQAMKPFRQVASSGKRVRGDGTGLGLPLTKAMVDANRANFSITSTPNEGTLVEITFPSQRVLAN

Specific function: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn r

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with divK (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=238, Percent_Identity=36.1344537815126, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI145693157, Length=318, Percent_Identity=28.3018867924528, Blast_Score=123, Evalue=8e-29,
Organism=Escherichia coli, GI1788549, Length=361, Percent_Identity=26.3157894736842, Blast_Score=119, Evalue=1e-27,
Organism=Escherichia coli, GI48994928, Length=364, Percent_Identity=25.8241758241758, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI87081816, Length=251, Percent_Identity=36.6533864541833, Blast_Score=117, Evalue=5e-27,
Organism=Escherichia coli, GI1788713, Length=277, Percent_Identity=28.8808664259928, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI1786912, Length=249, Percent_Identity=26.1044176706827, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=27.6018099547511, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1786600, Length=364, Percent_Identity=24.4505494505494, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1790300, Length=362, Percent_Identity=22.9281767955801, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=25.3275109170306, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1788393, Length=239, Percent_Identity=24.2677824267782, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 137065; Mature: 136934

Theoretical pI: Translated: 4.06; Mature: 4.06

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAVQYPFIDIAVHERVREGFGRGEAMALFSLDLQNVLWANGRGAALFGTPIVYDFLEQG
CCCCCCCEEHHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCEEECCHHHHHHHHCC
PKRQDVTFRQLAATAARLSKAGDSLPFTIRITSGFRSLAVTARAEIIEAEPGHPAILFSA
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCEEEEEH
LTDQAAPDVAECARRMIEGFDDPDIHMAVLNGDNEIIAASSGFSSLGITPHTARTLIKMA
HHCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHH
AGQSGHLVKRPVPTGKGYLPAATGQITTSPELNLLFVVETALGTLDPVNGFAEDRGFSED
CCCCCCEEECCCCCCCCCCCCCCCCEECCCCCEEEEEEEHHHCCCCCCCCHHHHCCCCCC
RDVAEDRNVAESRPQEIPAAAEPALPIAEAAPVIAATTSFDSVLDAVAGIEDVEDIQELP
HHHHHHCCHHHCCCCCCCCCCCCCCCHHHCCCEEEEECCHHHHHHHHHCHHHHHHHHHHH
SDFEEDVAAEQDEDGLLSMPDDKVETPAEPPVLDADAAADMAMTDDIEDLFELDADETVA
HHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHCCCCCCCC
PSIERTVTEDHTLEAQAEENTFADDEIAETEAEEATTAADDELTTETETANIGTGEEARP
CCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
FVFNAGARASRFVWKIDAEGRFSSISHEFAEAVGAKAAAVEGMGFADVAALFNLDPDGKI
EEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHCCCCCHHH
RELLGRRDTWSGKTIYWPVEGTSLMVPIDLAALPTYTRAREFDGFRGFGIVRLADATEDP
HHHHCCCCCCCCCEEEEECCCCEEEEEECHHHCCCHHHHHHCCCCCCCEEEEEECCCCCC
HATGLTFLNSEETEPAEVLPQQAVEDESHELLAFVDEDTETDDNPHPALPDEPAVDIDIA
CCCCEEEECCCCCCHHHHCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEC
GDAADGVLTEEQLDDETSPEVESPIEAPAPEPSYSDKVVHLEDRRSRSREGLTAGEQAAF
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHH
REIGRALAPSDMASEEKHEADAEGISAEPVVQDIQQDIAAETAKDASSDTGNDAETTEPV
HHHHHHCCCCHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EEDDLFADYVRGEQPAPVRAPTDEPTSAEKQVVTTDEKPVADIAASMVSPPVRTPSALTA
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCHHHH
ETLDQMPVALLVHAGDRLIHANPDFLRLTGYTSLTELEEVGGLEALLQRQELENMPDNEG
HHHHCCCEEEEEECCCEEEECCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHCCCCCCC
GMVVVSAENDIIPVKARLQSIRWEETKALMLSLVPLEEKPAAVMAANENTAENAEAGSNL
CEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCH
SLLQGEMEELHSILETATDGVVLLGDDGEIRSLNRSASALFNYDNGEIAGKPFVTLFAHE
HHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCHHEEECCCCCCCCCCEEEEEECC
SQRAVLDYLSGLANNGVASVLNDGREVIGREASGGFLPLFMTIGRLKSSHGYCAVIRDIT
CHHHHHHHHHHHCCCCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHH
QWKRTEEELRNAKRAAETANAHKTDFLARVSHEIRTPLNAIIGFSDMMATERFGPIGNPR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCC
YVEYANDIGRSGRHVLDIVNDLLDISKIEAGQMDVDFIAVPLNETVAEAVSLVQPQANNQ
EEHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCC
RVIIRTALAQSVPQIVADLRSIKQIVLNILSNAIRFTPSGGQIVVSTAYEANGSVSLRIR
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCEEEEEEE
DTGIGMTRAELEQAMKPFRQVASSGKRVRGDGTGLGLPLTKAMVDANRANFSITSTPNEG
CCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCCCEEEECCCCCC
TLVEITFPSQRVLAN
EEEEEECCCHHHHCC
>Mature Secondary Structure 
PAVQYPFIDIAVHERVREGFGRGEAMALFSLDLQNVLWANGRGAALFGTPIVYDFLEQG
CCCCCCEEHHHHHHHHHHHCCCCCEEEEEEECHHHHHCCCCCCCEEECCHHHHHHHHCC
PKRQDVTFRQLAATAARLSKAGDSLPFTIRITSGFRSLAVTARAEIIEAEPGHPAILFSA
CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCEEEEEH
LTDQAAPDVAECARRMIEGFDDPDIHMAVLNGDNEIIAASSGFSSLGITPHTARTLIKMA
HHCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHH
AGQSGHLVKRPVPTGKGYLPAATGQITTSPELNLLFVVETALGTLDPVNGFAEDRGFSED
CCCCCCEEECCCCCCCCCCCCCCCCEECCCCCEEEEEEEHHHCCCCCCCCHHHHCCCCCC
RDVAEDRNVAESRPQEIPAAAEPALPIAEAAPVIAATTSFDSVLDAVAGIEDVEDIQELP
HHHHHHCCHHHCCCCCCCCCCCCCCCHHHCCCEEEEECCHHHHHHHHHCHHHHHHHHHHH
SDFEEDVAAEQDEDGLLSMPDDKVETPAEPPVLDADAAADMAMTDDIEDLFELDADETVA
HHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHCCCCCCCC
PSIERTVTEDHTLEAQAEENTFADDEIAETEAEEATTAADDELTTETETANIGTGEEARP
CCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
FVFNAGARASRFVWKIDAEGRFSSISHEFAEAVGAKAAAVEGMGFADVAALFNLDPDGKI
EEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHCCCCCHHH
RELLGRRDTWSGKTIYWPVEGTSLMVPIDLAALPTYTRAREFDGFRGFGIVRLADATEDP
HHHHCCCCCCCCCEEEEECCCCEEEEEECHHHCCCHHHHHHCCCCCCCEEEEEECCCCCC
HATGLTFLNSEETEPAEVLPQQAVEDESHELLAFVDEDTETDDNPHPALPDEPAVDIDIA
CCCCEEEECCCCCCHHHHCHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEC
GDAADGVLTEEQLDDETSPEVESPIEAPAPEPSYSDKVVHLEDRRSRSREGLTAGEQAAF
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHH
REIGRALAPSDMASEEKHEADAEGISAEPVVQDIQQDIAAETAKDASSDTGNDAETTEPV
HHHHHHCCCCHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
EEDDLFADYVRGEQPAPVRAPTDEPTSAEKQVVTTDEKPVADIAASMVSPPVRTPSALTA
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCHHHH
ETLDQMPVALLVHAGDRLIHANPDFLRLTGYTSLTELEEVGGLEALLQRQELENMPDNEG
HHHHCCCEEEEEECCCEEEECCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHHCCCCCCC
GMVVVSAENDIIPVKARLQSIRWEETKALMLSLVPLEEKPAAVMAANENTAENAEAGSNL
CEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCH
SLLQGEMEELHSILETATDGVVLLGDDGEIRSLNRSASALFNYDNGEIAGKPFVTLFAHE
HHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCHHEEECCCCCCCCCCEEEEEECC
SQRAVLDYLSGLANNGVASVLNDGREVIGREASGGFLPLFMTIGRLKSSHGYCAVIRDIT
CHHHHHHHHHHHCCCCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHCCCCEEHHHHHHH
QWKRTEEELRNAKRAAETANAHKTDFLARVSHEIRTPLNAIIGFSDMMATERFGPIGNPR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCC
YVEYANDIGRSGRHVLDIVNDLLDISKIEAGQMDVDFIAVPLNETVAEAVSLVQPQANNQ
EEHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCC
RVIIRTALAQSVPQIVADLRSIKQIVLNILSNAIRFTPSGGQIVVSTAYEANGSVSLRIR
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEECCCCEEEEEEE
DTGIGMTRAELEQAMKPFRQVASSGKRVRGDGTGLGLPLTKAMVDANRANFSITSTPNEG
CCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHCCCCCEEEECCCCCC
TLVEITFPSQRVLAN
EEEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA