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The map label for this gene is galE [H]

Identifier: 15887879

GI number: 15887879

Start: 523619

End: 524650

Strand: Direct

Name: galE [H]

Synonym: Atu0530

Alternate gene names: 15887879

Gene position: 523619-524650 (Clockwise)

Preceding gene: 159184355

Following gene: 15887906

Centisome position: 18.43

GC content: 60.95

Gene sequence:

>1032_bases
ATGGCTGTTCTGGTCACGGGTGGGGCCGGTTATATAGGAAGCCACATGGTGTGGGCTTTGCTCGATGCCGGGGAAGAGGT
CGTTGTCGTCGACCGGCTTTCCACGGGGTCGCGCTGGGCAGTCGCGCCAGCGGCGCGTTTTTATCTTGGAGATGCGGCCG
ACCGCGCCTTGCTCGATCAGGTTTTTGAAGAAAACCACATCGAGACCATCTTCCACTTCGCCGGGTCCGTCAGCGTTCCC
GAGTCGATCAGCCAGCCGCTGGAATATTACGAAAACAATACCGGCACGACCCGCGCGCTTGTTGCCGCGGCGGTTCGCAG
CGGCATCCGCAATTTCATCTTCTCCTCGACAGCCGCCGTCTATGGAAACCAGCCCTTTGATGGTCCCGTTCCTGAAACGG
CGATCCTGAGCCCGGAAAATCCCTACGGCCTGTCGAAACTCGCGTCCGAAATCATGCTGCGCGATGTCGTGCAGGCGCAT
GATTTCAACTATGTGGCGCTGCGTTATTTCAACGTTGCCGGAGCCGACCCGCAGGGCCGCGCCGGGCCTTCGCCGACGGG
CGTTGCAAACCTTATCAAGGTTGCATGCGAAGCCGCGACCGGCCGCCGCGACCGGGTGGAGGTTTACGGGACGGATTACC
CGACCGCCGATGGAACCGGCGTTCGCGACTATATTCATGTCAGCGATCTGATTGATGCGCATATGCTGGCCATGGCGCAT
CTGCGCGCCGGCGGCGGTACACGAACCCTGAACTGCGGTTATGGTGTCGGTTATTCGGTTCTGGACGTCCTCCAGGCCGT
ACAGCGCGAATCCGCATGTGAATTCGCGGTCATCCATTGTCCCCGCCGTCCGGGTGACATTGCGGCCATGGTGGCGGATT
CGTCGCGTATCCAGTCGGAATTAGGCTGGCGTCCTCGCTTCAACGATCTGGCGACCATCGTTCGCACTGCGCTTCAATGG
GAAGCCAAGCGTCAGGCCCAGCAAAGCGGCAGAATACCGCCGATGCGGCGCAAGCTGGCAGCGATAGGCTGA

Upstream 100 bases:

>100_bases
TGGGGTGGGGGATCGGTTGTGTATTCGCTGTGCAAGTAATCAATGATGAAGAATTATTGGCTTTGATAGGCTCAAGAAAA
GCAAACAGGGAAGTAATGTC

Downstream 100 bases:

>100_bases
GCCGTCTTTATGTCACGGGACGTGGCTTTTCGTGACGGAAGGATGCGGTATCGGCCGATCCGAAAGTGCGGCCGGGCGAA
GCCAACGGTCCCGGTCGAAA

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MAVLVTGGAGYIGSHMVWALLDAGEEVVVVDRLSTGSRWAVAPAARFYLGDAADRALLDQVFEENHIETIFHFAGSVSVP
ESISQPLEYYENNTGTTRALVAAAVRSGIRNFIFSSTAAVYGNQPFDGPVPETAILSPENPYGLSKLASEIMLRDVVQAH
DFNYVALRYFNVAGADPQGRAGPSPTGVANLIKVACEAATGRRDRVEVYGTDYPTADGTGVRDYIHVSDLIDAHMLAMAH
LRAGGGTRTLNCGYGVGYSVLDVLQAVQRESACEFAVIHCPRRPGDIAAMVADSSRIQSELGWRPRFNDLATIVRTALQW
EAKRQAQQSGRIPPMRRKLAAIG

Sequences:

>Translated_343_residues
MAVLVTGGAGYIGSHMVWALLDAGEEVVVVDRLSTGSRWAVAPAARFYLGDAADRALLDQVFEENHIETIFHFAGSVSVP
ESISQPLEYYENNTGTTRALVAAAVRSGIRNFIFSSTAAVYGNQPFDGPVPETAILSPENPYGLSKLASEIMLRDVVQAH
DFNYVALRYFNVAGADPQGRAGPSPTGVANLIKVACEAATGRRDRVEVYGTDYPTADGTGVRDYIHVSDLIDAHMLAMAH
LRAGGGTRTLNCGYGVGYSVLDVLQAVQRESACEFAVIHCPRRPGDIAAMVADSSRIQSELGWRPRFNDLATIVRTALQW
EAKRQAQQSGRIPPMRRKLAAIG
>Mature_342_residues
AVLVTGGAGYIGSHMVWALLDAGEEVVVVDRLSTGSRWAVAPAARFYLGDAADRALLDQVFEENHIETIFHFAGSVSVPE
SISQPLEYYENNTGTTRALVAAAVRSGIRNFIFSSTAAVYGNQPFDGPVPETAILSPENPYGLSKLASEIMLRDVVQAHD
FNYVALRYFNVAGADPQGRAGPSPTGVANLIKVACEAATGRRDRVEVYGTDYPTADGTGVRDYIHVSDLIDAHMLAMAHL
RAGGGTRTLNCGYGVGYSVLDVLQAVQRESACEFAVIHCPRRPGDIAAMVADSSRIQSELGWRPRFNDLATIVRTALQWE
AKRQAQQSGRIPPMRRKLAAIG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=319, Percent_Identity=41.3793103448276, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI56118217, Length=319, Percent_Identity=41.3793103448276, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI189083684, Length=319, Percent_Identity=41.3793103448276, Blast_Score=220, Evalue=1e-57,
Organism=Homo sapiens, GI7657641, Length=335, Percent_Identity=25.6716417910448, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI42516563, Length=336, Percent_Identity=25, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786974, Length=333, Percent_Identity=41.7417417417417, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI48994969, Length=354, Percent_Identity=28.2485875706215, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788353, Length=353, Percent_Identity=25.4957507082153, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790049, Length=326, Percent_Identity=24.5398773006135, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=343, Percent_Identity=37.3177842565598, Blast_Score=209, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71982038, Length=345, Percent_Identity=37.1014492753623, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17568069, Length=329, Percent_Identity=25.531914893617, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115532424, Length=334, Percent_Identity=25.748502994012, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=356, Percent_Identity=23.0337078651685, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=319, Percent_Identity=39.4984326018809, Blast_Score=213, Evalue=4e-56,
Organism=Drosophila melanogaster, GI19923002, Length=319, Percent_Identity=40.4388714733542, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21356223, Length=313, Percent_Identity=26.8370607028754, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36997; Mature: 36866

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVLVTGGAGYIGSHMVWALLDAGEEVVVVDRLSTGSRWAVAPAARFYLGDAADRALLDQ
CEEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECHHHHHHHCCHHHHHHHHH
VFEENHIETIFHFAGSVSVPESISQPLEYYENNTGTTRALVAAAVRSGIRNFIFSSTAAV
HHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
YGNQPFDGPVPETAILSPENPYGLSKLASEIMLRDVVQAHDFNYVALRYFNVAGADPQGR
CCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCC
AGPSPTGVANLIKVACEAATGRRDRVEVYGTDYPTADGTGVRDYIHVSDLIDAHMLAMAH
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRAGGGTRTLNCGYGVGYSVLDVLQAVQRESACEFAVIHCPRRPGDIAAMVADSSRIQSE
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCHHHHHHH
LGWRPRFNDLATIVRTALQWEAKRQAQQSGRIPPMRRKLAAIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC
>Mature Secondary Structure 
AVLVTGGAGYIGSHMVWALLDAGEEVVVVDRLSTGSRWAVAPAARFYLGDAADRALLDQ
EEEEECCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCEEECHHHHHHHCCHHHHHHHHH
VFEENHIETIFHFAGSVSVPESISQPLEYYENNTGTTRALVAAAVRSGIRNFIFSSTAAV
HHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
YGNQPFDGPVPETAILSPENPYGLSKLASEIMLRDVVQAHDFNYVALRYFNVAGADPQGR
CCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCC
AGPSPTGVANLIKVACEAATGRRDRVEVYGTDYPTADGTGVRDYIHVSDLIDAHMLAMAH
CCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
LRAGGGTRTLNCGYGVGYSVLDVLQAVQRESACEFAVIHCPRRPGDIAAMVADSSRIQSE
HHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCHHHHHHH
LGWRPRFNDLATIVRTALQWEAKRQAQQSGRIPPMRRKLAAIG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8026752 [H]