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The map label for this gene is gntK [H]

Identifier: 15887548

GI number: 15887548

Start: 199684

End: 200175

Strand: Reverse

Name: gntK [H]

Synonym: Atu0195

Alternate gene names: 15887548

Gene position: 200175-199684 (Counterclockwise)

Preceding gene: 159184204

Following gene: 15887540

Centisome position: 7.04

GC content: 59.96

Gene sequence:

>492_bases
GTGATGGGAGTGAGCGGCTCCGGCAAGTCCACGGTCGCAGAGGGACTGGCGGAGAAGCTGGGTATCGCCTTCATTGAAGG
CGACAAGCTGCACCCGAAATCCAATGTCGACAAGATGTCGGAAGGCATTCCGCTGACCGACGACGACCGCTGGCCATGGC
TCGATCTGATCGGCGCGGAACTGCGCAATGGCAGTGAAGGCAAGGGCGTTTTGGTTTCCTGCTCCGCCCTCAAGAAAATC
TATCGCGACCGCCTTCGTGAGGCGACCGGTGGCCCACTCGCCTTCGTTTATCTTGATGGCAGCCTGGAGCTTCTCAGCCG
GCGCATGGGTGAACGCAAGGGTCATTTCATGCCGCTCTCGCTGCTTCAGACCCAGCTTGCCACGCTGGAAGTGCCGACCG
GGGAACCGGGTGTCGTCACGGTCAGCATCGATTCCACACCTGAGGAGATCGTAGCGAATGCGCTGGCTGGCCTGAAGACG
CTAAAATTCTAG

Upstream 100 bases:

>100_bases
GGAGCCGTCCAAATTTAAGGTTCCCGGCACCCGCCGCACATGGTAGGGGCTGACCGTCGAAACAGAAACATCAGAGGTTC
GGGTGACACAGGCAATCGTC

Downstream 100 bases:

>100_bases
AGCACGTCCGGTCTAAACGGAAGCGGGAGACGCGCTCTATCTCTTTGTTTTATCTTATTGTCCGGACGTAAACCGCTACG
CAGTTTTACTGGAAATGCTC

Product: gluconokinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MMGVSGSGKSTVAEGLAEKLGIAFIEGDKLHPKSNVDKMSEGIPLTDDDRWPWLDLIGAELRNGSEGKGVLVSCSALKKI
YRDRLREATGGPLAFVYLDGSLELLSRRMGERKGHFMPLSLLQTQLATLEVPTGEPGVVTVSIDSTPEEIVANALAGLKT
LKF

Sequences:

>Translated_163_residues
MMGVSGSGKSTVAEGLAEKLGIAFIEGDKLHPKSNVDKMSEGIPLTDDDRWPWLDLIGAELRNGSEGKGVLVSCSALKKI
YRDRLREATGGPLAFVYLDGSLELLSRRMGERKGHFMPLSLLQTQLATLEVPTGEPGVVTVSIDSTPEEIVANALAGLKT
LKF
>Mature_163_residues
MMGVSGSGKSTVAEGLAEKLGIAFIEGDKLHPKSNVDKMSEGIPLTDDDRWPWLDLIGAELRNGSEGKGVLVSCSALKKI
YRDRLREATGGPLAFVYLDGSLELLSRRMGERKGHFMPLSLLQTQLATLEVPTGEPGVVTVSIDSTPEEIVANALAGLKT
LKF

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=177, Percent_Identity=43.5028248587571, Blast_Score=137, Evalue=6e-33,
Organism=Escherichia coli, GI87082265, Length=162, Percent_Identity=46.9135802469136, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1790719, Length=147, Percent_Identity=46.2585034013605, Blast_Score=128, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25146487, Length=150, Percent_Identity=45.3333333333333, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320454, Length=141, Percent_Identity=39.7163120567376, Blast_Score=110, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 17481; Mature: 17481

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGVSGSGKSTVAEGLAEKLGIAFIEGDKLHPKSNVDKMSEGIPLTDDDRWPWLDLIGAE
CCCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHH
LRNGSEGKGVLVSCSALKKIYRDRLREATGGPLAFVYLDGSLELLSRRMGERKGHFMPLS
HCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHH
LLQTQLATLEVPTGEPGVVTVSIDSTPEEIVANALAGLKTLKF
HHHHHHHEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMGVSGSGKSTVAEGLAEKLGIAFIEGDKLHPKSNVDKMSEGIPLTDDDRWPWLDLIGAE
CCCCCCCCHHHHHHHHHHHHCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHH
LRNGSEGKGVLVSCSALKKIYRDRLREATGGPLAFVYLDGSLELLSRRMGERKGHFMPLS
HCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHH
LLQTQLATLEVPTGEPGVVTVSIDSTPEEIVANALAGLKTLKF
HHHHHHHEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]