Click here to switch to the map view.

The map label for this gene is pheA [H]

Identifier: 15887453

GI number: 15887453

Start: 103016

End: 103879

Strand: Reverse

Name: pheA [H]

Synonym: Atu0099

Alternate gene names: 15887453

Gene position: 103879-103016 (Counterclockwise)

Preceding gene: 15887454

Following gene: 15887450

Centisome position: 3.66

GC content: 57.29

Gene sequence:

>864_bases
ATGAATTTGATTACAAATCGCATTGCCTTTCAGGGCGAGTTCGGCGCGAATTCCGACATGGCATGCCGTGACATGTTTCC
GGATATGGAGCCATTGCCATGCCCGACATTCGAGGATGCCTTCAACGCTATCGAAAATGGCGAAGCCGATCTCGGCATGA
TCCCGATTGAAAACACGCTGGCCGGCCGAGTCGCGGATATTCATCACCTGCTGCCCGAATCACGCCTGCACATCATCGGC
GAATATTTCATGCCGATCCGTTTCCAGCTGATGGTGGTGCCGGGCGTGACGAAAGACGAGATCCGCACCGTCCACAGCCA
TATCCATGCACTGGGCCAGTGCCGCAAGATCATCCGTTCGAACGGCTGGAAGCCCGTCATCGCCGGCGATACGGCGGGCT
CCGCAAGGCTGGTTTCCGAAAAGGGCGACCGCAGCATGGCGGCTCTCGCGCCGCGTCTTGCCGCGGATCTCTACGGTCTC
GATATTCTCGCTGAAAATGTCGAGGATTCGGAAAACAACGTTACGCGCTTCGTCGTGCTCTCCCGCGATGAGAACTGGGC
CAAGCGTCAGTCGAGCGACGAAATTGTCGTCACGACTTTTGTCTTCAATGTTCGCAACATTCCGGCCGCGCTCTACAAGG
CCATGGGCGGTTTTGCCACCAACGGCATCAATATGACGAAGCTCGAAAGCTACCAGCTCGGCGGCAAATTCGTGGCGACG
CAGTTTTATGCCGATATTGAAGGCCACCCCGATGACGAACCGGTGCGGCATGCGCTGGACGAGCTGCGCTTCTTCTCGGA
AAAAGTCCGCATTCTCGGCGTCTACAACGGCCATGCGATGCGCGGCAAGCTCAACCAGAGCTGA

Upstream 100 bases:

>100_bases
CGGAAATCGTCCGGTCTGTTCCGCTTGGCGTCGACACGCCGCACGATCTCGAAAAAGCCCGCAAGATTCTTGCAGGCAGA
ACCCTCTAACGGACAGTCCC

Downstream 100 bases:

>100_bases
GCCTGCCGCAACCCCTCACTCGGGCCATTCCACCCAGTCGCGCATCAGCCGATGCGCGATGGCGCCGATCGGCGGGGCTG
AAAAACCTTCCCCCGCCGGG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNLITNRIAFQGEFGANSDMACRDMFPDMEPLPCPTFEDAFNAIENGEADLGMIPIENTLAGRVADIHHLLPESRLHIIG
EYFMPIRFQLMVVPGVTKDEIRTVHSHIHALGQCRKIIRSNGWKPVIAGDTAGSARLVSEKGDRSMAALAPRLAADLYGL
DILAENVEDSENNVTRFVVLSRDENWAKRQSSDEIVVTTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGKFVAT
QFYADIEGHPDDEPVRHALDELRFFSEKVRILGVYNGHAMRGKLNQS

Sequences:

>Translated_287_residues
MNLITNRIAFQGEFGANSDMACRDMFPDMEPLPCPTFEDAFNAIENGEADLGMIPIENTLAGRVADIHHLLPESRLHIIG
EYFMPIRFQLMVVPGVTKDEIRTVHSHIHALGQCRKIIRSNGWKPVIAGDTAGSARLVSEKGDRSMAALAPRLAADLYGL
DILAENVEDSENNVTRFVVLSRDENWAKRQSSDEIVVTTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGKFVAT
QFYADIEGHPDDEPVRHALDELRFFSEKVRILGVYNGHAMRGKLNQS
>Mature_287_residues
MNLITNRIAFQGEFGANSDMACRDMFPDMEPLPCPTFEDAFNAIENGEADLGMIPIENTLAGRVADIHHLLPESRLHIIG
EYFMPIRFQLMVVPGVTKDEIRTVHSHIHALGQCRKIIRSNGWKPVIAGDTAGSARLVSEKGDRSMAALAPRLAADLYGL
DILAENVEDSENNVTRFVVLSRDENWAKRQSSDEIVVTTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGKFVAT
QFYADIEGHPDDEPVRHALDELRFFSEKVRILGVYNGHAMRGKLNQS

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=275, Percent_Identity=32, Blast_Score=130, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31923; Mature: 31923

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLITNRIAFQGEFGANSDMACRDMFPDMEPLPCPTFEDAFNAIENGEADLGMIPIENTL
CCCCCCCEEEECCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHH
AGRVADIHHLLPESRLHIIGEYFMPIRFQLMVVPGVTKDEIRTVHSHIHALGQCRKIIRS
HHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
NGWKPVIAGDTAGSARLVSEKGDRSMAALAPRLAADLYGLDILAENVEDSENNVTRFVVL
CCCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
SRDENWAKRQSSDEIVVTTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGKFVAT
ECCCCHHHHCCCCCEEEEEEEEEHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEE
QFYADIEGHPDDEPVRHALDELRFFSEKVRILGVYNGHAMRGKLNQS
EEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCEECCCCCCC
>Mature Secondary Structure
MNLITNRIAFQGEFGANSDMACRDMFPDMEPLPCPTFEDAFNAIENGEADLGMIPIENTL
CCCCCCCEEEECCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCHHH
AGRVADIHHLLPESRLHIIGEYFMPIRFQLMVVPGVTKDEIRTVHSHIHALGQCRKIIRS
HHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHC
NGWKPVIAGDTAGSARLVSEKGDRSMAALAPRLAADLYGLDILAENVEDSENNVTRFVVL
CCCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEE
SRDENWAKRQSSDEIVVTTFVFNVRNIPAALYKAMGGFATNGINMTKLESYQLGGKFVAT
ECCCCHHHHCCCCCEEEEEEEEEHHCCHHHHHHHHCCCCCCCCCEEEECCCCCCCEEEEE
QFYADIEGHPDDEPVRHALDELRFFSEKVRILGVYNGHAMRGKLNQS
EEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEEECCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]