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The map label for this gene is frcB [H]

Identifier: 15887417

GI number: 15887417

Start: 66551

End: 67573

Strand: Direct

Name: frcB [H]

Synonym: Atu0063

Alternate gene names: 15887417

Gene position: 66551-67573 (Clockwise)

Preceding gene: 15887415

Following gene: 159184145

Centisome position: 2.34

GC content: 59.04

Gene sequence:

>1023_bases
ATGAAGACCACTGTTTCCGCTCTTCTGGGCGCGCTCGCGCTTGGCGTTTCTTTCGCTTCCGCTGCATCTGCCGCCGATAC
GTCGGTTTGCCTGATTACCAAAACCGACACCAACCCCTTTTTCGTCAAGATGAAAGAAGGCGCGACCGCCAAGGCGAAAG
AACTCGGCGTGACGCTGAAGTCCTATGCCGGCAAGATCGACGGTGATTCCGAAAGCCAGGTTGCCGCGATCGAGACCTGC
ATCGCCGATGGCGCCAAGGGTATCCTGATCACCGCATCGGACACCAAGGGCATCGTTCCGGCCGTACAGAAGGCGCGTGA
CGCCGGCCTTCTCGTCATTGCCCTCGATACGCCTCTGGAACCCGTCGATGCCGCCGATTCCACTTTCGCCACCGACAATC
TTCTGGCCGGCGAGCTGATCGGCAAATGGGCCGCCGGTACCCTTGGCGACAAGGCCAAGGACGCAAAAATTGCCTTCCTC
AACCTTACCCCCTCCCAGCCGACGGTTGACGTGCTGCGCAACCAGGGCTTCATGAAGGGCTTCGGCATCGACGTGAAGGA
CATCAACAAGATCGGCGATGAAGACGACAAGCGCATCGTTGGCCACGACGTTACCAACGGTAACGAAGAAGGTGGCCGTT
CGGCGATGGAAAATCTGCTTCAGAAAGACCCGACGATCAACGTCGTCCACACGATCAACGAGCCTGCTGCTGCTGGCGCT
TATGAAGCGCTGAAGGCCGTCGGCCGCGAAAAGGACGTACTGATCGTTTCCGTCGATGGCGGTTGCCCAGGCGTTAAGAA
CGTCGCGGAAGGCGTGATTGGTGCAACGTCCCAGCAATATCCGTTGCTGATGGCGGCGCTCGGTGTCGAAGCCGTCAAGA
AGTTTGCCGACACGGGCGAAAAGCCGAAGCCGACAGCTGGCAAGAACTTTTTCGACACCGGCGTGACGCTGGTAACGGAC
AAGCCGGTCAAGGGCCTCGATTCCATCGACACCAAGGAAGGCCTGAAGAAGTGCTGGGGCTGA

Upstream 100 bases:

>100_bases
TCCTTTGGTGGTTCCATCTGCATCAACGGTCGTCGATCTCGGAGGAGACGGGATCGTCGGGTAACCGTCACGGTGCTCAA
ATATCCATTGGGAGGATCTC

Downstream 100 bases:

>100_bases
TGCCGCGCCTTTGAAAAGCCGCGGGGGCAATCTGCCCCCGCCCATTAACCTGAATGGTTTAAGAGCTCGATCTGGGTGAT
CGGACAGAAACAAACGAGCG

Product: ABC transporter, substrate binding protein (sugar)

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKTTVSALLGALALGVSFASAASAADTSVCLITKTDTNPFFVKMKEGATAKAKELGVTLKSYAGKIDGDSESQVAAIETC
IADGAKGILITASDTKGIVPAVQKARDAGLLVIALDTPLEPVDAADSTFATDNLLAGELIGKWAAGTLGDKAKDAKIAFL
NLTPSQPTVDVLRNQGFMKGFGIDVKDINKIGDEDDKRIVGHDVTNGNEEGGRSAMENLLQKDPTINVVHTINEPAAAGA
YEALKAVGREKDVLIVSVDGGCPGVKNVAEGVIGATSQQYPLLMAALGVEAVKKFADTGEKPKPTAGKNFFDTGVTLVTD
KPVKGLDSIDTKEGLKKCWG

Sequences:

>Translated_340_residues
MKTTVSALLGALALGVSFASAASAADTSVCLITKTDTNPFFVKMKEGATAKAKELGVTLKSYAGKIDGDSESQVAAIETC
IADGAKGILITASDTKGIVPAVQKARDAGLLVIALDTPLEPVDAADSTFATDNLLAGELIGKWAAGTLGDKAKDAKIAFL
NLTPSQPTVDVLRNQGFMKGFGIDVKDINKIGDEDDKRIVGHDVTNGNEEGGRSAMENLLQKDPTINVVHTINEPAAAGA
YEALKAVGREKDVLIVSVDGGCPGVKNVAEGVIGATSQQYPLLMAALGVEAVKKFADTGEKPKPTAGKNFFDTGVTLVTD
KPVKGLDSIDTKEGLKKCWG
>Mature_340_residues
MKTTVSALLGALALGVSFASAASAADTSVCLITKTDTNPFFVKMKEGATAKAKELGVTLKSYAGKIDGDSESQVAAIETC
IADGAKGILITASDTKGIVPAVQKARDAGLLVIALDTPLEPVDAADSTFATDNLLAGELIGKWAAGTLGDKAKDAKIAFL
NLTPSQPTVDVLRNQGFMKGFGIDVKDINKIGDEDDKRIVGHDVTNGNEEGGRSAMENLLQKDPTINVVHTINEPAAAGA
YEALKAVGREKDVLIVSVDGGCPGVKNVAEGVIGATSQQYPLLMAALGVEAVKKFADTGEKPKPTAGKNFFDTGVTLVTD
KPVKGLDSIDTKEGLKKCWG

Specific function: Involved in the high-affinity D-ribose membrane transport system and also serves as the primary chemoreceptor for chemotaxis [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790192, Length=297, Percent_Identity=30.3030303030303, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790526, Length=283, Percent_Identity=28.2685512367491, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790674, Length=263, Percent_Identity=26.615969581749, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: 3940 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5900 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 1520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35175; Mature: 35175

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTVSALLGALALGVSFASAASAADTSVCLITKTDTNPFFVKMKEGATAKAKELGVTLK
CCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHCCCHH
SYAGKIDGDSESQVAAIETCIADGAKGILITASDTKGIVPAVQKARDAGLLVIALDTPLE
HHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCC
PVDAADSTFATDNLLAGELIGKWAAGTLGDKAKDAKIAFLNLTPSQPTVDVLRNQGFMKG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCC
FGIDVKDINKIGDEDDKRIVGHDVTNGNEEGGRSAMENLLQKDPTINVVHTINEPAAAGA
CCCCHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHH
YEALKAVGREKDVLIVSVDGGCPGVKNVAEGVIGATSQQYPLLMAALGVEAVKKFADTGE
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
KPKPTAGKNFFDTGVTLVTDKPVKGLDSIDTKEGLKKCWG
CCCCCCCCCHHHCCEEEEECCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKTTVSALLGALALGVSFASAASAADTSVCLITKTDTNPFFVKMKEGATAKAKELGVTLK
CCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHCCCHH
SYAGKIDGDSESQVAAIETCIADGAKGILITASDTKGIVPAVQKARDAGLLVIALDTPLE
HHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCC
PVDAADSTFATDNLLAGELIGKWAAGTLGDKAKDAKIAFLNLTPSQPTVDVLRNQGFMKG
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCCC
FGIDVKDINKIGDEDDKRIVGHDVTNGNEEGGRSAMENLLQKDPTINVVHTINEPAAAGA
CCCCHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHH
YEALKAVGREKDVLIVSVDGGCPGVKNVAEGVIGATSQQYPLLMAALGVEAVKKFADTGE
HHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCC
KPKPTAGKNFFDTGVTLVTDKPVKGLDSIDTKEGLKKCWG
CCCCCCCCCHHHCCEEEEECCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]