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The map label for this gene is frcC [H]

Identifier: 159184145

GI number: 159184145

Start: 67798

End: 68880

Strand: Direct

Name: frcC [H]

Synonym: Atu0064

Alternate gene names: 159184145

Gene position: 67798-68880 (Clockwise)

Preceding gene: 15887417

Following gene: 15887419

Centisome position: 2.39

GC content: 56.97

Gene sequence:

>1083_bases
ATGAGCGATCAGCCAGTGCGGGCGCAACCGCACAATGAATTTGAAAAAGTGCTGTCAGGAAGTTCGACCCAGGTCGCTGC
TTTTGATACGCACAACAAGAGTTTGCTGGAAAAATTCCAGCACTTTCTGCATTCCAGCCCTGCGGCTGTTCCCCTGATCG
TTCTGGTGCTGTCACTTGCCATCTTCGGCATGACGCTGGGCGGCAAGTTCTTTTCGGCTTTCTCGCTGACGCTTATTCTT
CAGCAGGTGGCAATCGTCGGCATTGTCGGCGCGGCGCAGTCGCTGGTCATTCTGACCGCGGGTATCGATCTTTCGGTCGG
TGCCATCATGGTTCTCTCCTCCGTCGTCATGGGCCAGTTCACCTTCCGTTATGGTCTGCCTGCGGAACTTTCCATTATCT
GCGGTCTCGCAGTCGGCGCGTTTTGTGGTTTCATCAACGGCGTGCTGGTATCGCGCATGCGGCTGCCGCCCTTCATCGTC
ACGCTCGGCATGTGGCAGATCGTGCTGGCCACCAATTTCCTCTATTCGGCTAACGAGACGATCCGCGCTCAGGACATTGT
CCAGCAAGCGCCCATTCTTCAGTTTTTCGGCAATAATATTCGTATCGGCAATGCCGTCTTCACCTACGGCGTTCTCGCGA
TGGTTCTGCTCGTCGCTTTGCTCTGGTATGTGCTCAACCGCACCGCTTGGGGGCGCCATCTTTATGCGGTCGGTGACGAT
CCAGACGCGGCTGAACTTGCTGGCGTTAACGTCAAGCGCATGCTGACGACCGTCTATACCCTGTCCGGCCTTATCTGCGC
CTTCGCGGGTTGGGCTCTCATCGGTCGCATCGGCTCGGTGTCGCCGACTGCCGGTCAGTTCGCCAACATTGAATCCATCA
CTGCAGTGGTCATCGGCGGCATCTCGCTGTTCGGCGGACGCGGTTCCATCATGGGCATGATCTTCGGTGCGCTGATCGTC
GGCGTCTTTTCGCTGGGCCTCAGGCTCATCGGGACAGATCCGCAATGGACCTATCTGTTGATTGGCGTCCTCATCATCTT
GGCCGTGGCAATCGACCAGTGGATTAGAAAGGTAGCAGGCTGA

Upstream 100 bases:

>100_bases
GAGGCACGCTTCTCAACAGTTTGAATCTACGCATTATCCCCCTCCGGAGAGCGATCCCGGCTTCAGGGCTGATGCGATGG
AGCGATCGGGAGGAAAATCC

Downstream 100 bases:

>100_bases
TGGCAAAAGAACCTATCCTCACAGCGCGCAATCTCGTTAAACGCTACGGTCGCGTGACCGCACTCGATAATGCTGACTTC
GATCTTTATCCGGGCGAAAT

Product: ABC transporter, membrane spanning protein (sugar)

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSDQPVRAQPHNEFEKVLSGSSTQVAAFDTHNKSLLEKFQHFLHSSPAAVPLIVLVLSLAIFGMTLGGKFFSAFSLTLIL
QQVAIVGIVGAAQSLVILTAGIDLSVGAIMVLSSVVMGQFTFRYGLPAELSIICGLAVGAFCGFINGVLVSRMRLPPFIV
TLGMWQIVLATNFLYSANETIRAQDIVQQAPILQFFGNNIRIGNAVFTYGVLAMVLLVALLWYVLNRTAWGRHLYAVGDD
PDAAELAGVNVKRMLTTVYTLSGLICAFAGWALIGRIGSVSPTAGQFANIESITAVVIGGISLFGGRGSIMGMIFGALIV
GVFSLGLRLIGTDPQWTYLLIGVLIILAVAIDQWIRKVAG

Sequences:

>Translated_360_residues
MSDQPVRAQPHNEFEKVLSGSSTQVAAFDTHNKSLLEKFQHFLHSSPAAVPLIVLVLSLAIFGMTLGGKFFSAFSLTLIL
QQVAIVGIVGAAQSLVILTAGIDLSVGAIMVLSSVVMGQFTFRYGLPAELSIICGLAVGAFCGFINGVLVSRMRLPPFIV
TLGMWQIVLATNFLYSANETIRAQDIVQQAPILQFFGNNIRIGNAVFTYGVLAMVLLVALLWYVLNRTAWGRHLYAVGDD
PDAAELAGVNVKRMLTTVYTLSGLICAFAGWALIGRIGSVSPTAGQFANIESITAVVIGGISLFGGRGSIMGMIFGALIV
GVFSLGLRLIGTDPQWTYLLIGVLIILAVAIDQWIRKVAG
>Mature_359_residues
SDQPVRAQPHNEFEKVLSGSSTQVAAFDTHNKSLLEKFQHFLHSSPAAVPLIVLVLSLAIFGMTLGGKFFSAFSLTLILQ
QVAIVGIVGAAQSLVILTAGIDLSVGAIMVLSSVVMGQFTFRYGLPAELSIICGLAVGAFCGFINGVLVSRMRLPPFIVT
LGMWQIVLATNFLYSANETIRAQDIVQQAPILQFFGNNIRIGNAVFTYGVLAMVLLVALLWYVLNRTAWGRHLYAVGDDP
DAAELAGVNVKRMLTTVYTLSGLICAFAGWALIGRIGSVSPTAGQFANIESITAVVIGGISLFGGRGSIMGMIFGALIVG
VFSLGLRLIGTDPQWTYLLIGVLIILAVAIDQWIRKVAG

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=304, Percent_Identity=33.8815789473684, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790524, Length=304, Percent_Identity=32.5657894736842, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788896, Length=271, Percent_Identity=33.5793357933579, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788471, Length=282, Percent_Identity=34.7517730496454, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789992, Length=135, Percent_Identity=39.2592592592593, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082395, Length=280, Percent_Identity=28.9285714285714, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI145693214, Length=259, Percent_Identity=33.976833976834, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787794, Length=284, Percent_Identity=29.9295774647887, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI145693152, Length=214, Percent_Identity=30.8411214953271, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787793, Length=295, Percent_Identity=29.1525423728814, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 38364; Mature: 38233

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQPVRAQPHNEFEKVLSGSSTQVAAFDTHNKSLLEKFQHFLHSSPAAVPLIVLVLSLA
CCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IFGMTLGGKFFSAFSLTLILQQVAIVGIVGAAQSLVILTAGIDLSVGAIMVLSSVVMGQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHH
TFRYGLPAELSIICGLAVGAFCGFINGVLVSRMRLPPFIVTLGMWQIVLATNFLYSANET
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCH
IRAQDIVQQAPILQFFGNNIRIGNAVFTYGVLAMVLLVALLWYVLNRTAWGRHLYAVGDD
HHHHHHHHHCCHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
PDAAELAGVNVKRMLTTVYTLSGLICAFAGWALIGRIGSVSPTAGQFANIESITAVVIGG
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
ISLFGGRGSIMGMIFGALIVGVFSLGLRLIGTDPQWTYLLIGVLIILAVAIDQWIRKVAG
HHHCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDQPVRAQPHNEFEKVLSGSSTQVAAFDTHNKSLLEKFQHFLHSSPAAVPLIVLVLSLA
CCCCCCCCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
IFGMTLGGKFFSAFSLTLILQQVAIVGIVGAAQSLVILTAGIDLSVGAIMVLSSVVMGQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHHH
TFRYGLPAELSIICGLAVGAFCGFINGVLVSRMRLPPFIVTLGMWQIVLATNFLYSANET
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCH
IRAQDIVQQAPILQFFGNNIRIGNAVFTYGVLAMVLLVALLWYVLNRTAWGRHLYAVGDD
HHHHHHHHHCCHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCC
PDAAELAGVNVKRMLTTVYTLSGLICAFAGWALIGRIGSVSPTAGQFANIESITAVVIGG
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHH
ISLFGGRGSIMGMIFGALIVGVFSLGLRLIGTDPQWTYLLIGVLIILAVAIDQWIRKVAG
HHHCCCCHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]