Click here to switch to the map view.

The map label for this gene is recQ [H]

Identifier: 15887415

GI number: 15887415

Start: 63196

End: 65004

Strand: Direct

Name: recQ [H]

Synonym: Atu0061

Alternate gene names: 15887415

Gene position: 63196-65004 (Clockwise)

Preceding gene: 159184144

Following gene: 15887417

Centisome position: 2.22

GC content: 58.65

Gene sequence:

>1809_bases
GTGAATGCCGATCCCTTAAATATCCTCAAGGCCGTCTATGGTTATGATGCGTTTCGCGGACGGCAGGGCGAAATCATCCA
GCATGTGGTGGCAGGCAACAATGCGTTCGTTCTGATGCCGACGGGTGGCGGAAAGTCGCTTTGTTACCAGATCCCTGCGC
TTGCCAGAGAGGGCATGGGGCTTGTCGTTTCGCCGCTGATCGCGCTGATGGTTGATCAGGTTGCCGCGCTGCGTCAGGCC
GGTGTAAGAGCCGAAGCTCTCAATTCAGACCTTTCTCCGGAAGAGCGCCGCACGCTCTGGCGGGATGTGCGAGCCGGCAA
TGTCGATATTCTCTACGCCGCGCCGGAAACTCTTTTGAAGCCTGATGTCCTTGATGCACTTCAATCCATTGACCTGTCGC
TGATCGCCGTCGACGAGGCCCATTGCCTGTCGCAATGGGGGCATGATTTCCGACCGCCTTATCGCCAGCTCGATATGTTG
ATCGCGCGTTTTCCCAATACACCGAGGATGGCGCTGACGGCGACGGCTGACGAACCCACCCGTGCAGAGATTCTCGGCCA
TCTTGCCATTGATGAAGCTGATGCCTTCATTGCCGGCTTCGATCGCCCCAACATCCGCTATGCGATCATGGAGAAGGACA
ATCCCCGTACTCAGTTGAAACGTTTTCTCAACGGCCGGGAAAATGAAAGCGGCATCGTTTATTGCCTGTCGAAACGCAAA
GTGGAAGAAACGGCGGCATGGCTGCGGGAAGAGGGCCGTGACGCGTTGCCCTATCACGCCGGCATGGATAAGGCCGCCCG
CGAGGAAAACCAGACCCGTTTCCAGCATGGTGAGGCAGTCATCATCGTCGCGACGGTTGCCTTCGGTATGGGCATCGACA
AGCCGGATGTGCGCTTCGTCGTCCATATCGATCTGCCCGGAAGCATCGAGGCCTATTATCAGGAAACCGGCCGGGCCGGG
CGCGATGGCCTGCCGTCCGATGTATTGATGCTCTATGGTTATGAAGATATTGCCCTGCGCAACCGTTTCATCGAGGAGTC
GGACGCTGCGGACCAGCGCAAATACATGGAACGACAGAAGCTCGATGCGCTGCTTGGCCTTGCGGAAACCGCGGGTTGCC
GGAGGCAGGTGCTGCTCTCCTATTTTGGCGACCGGTGCGAGCCTTGCGGCAATTGCGATACCTGCTCGTCGCCGCCCGAT
CTATTCGAGGGGGCCATTGCCGCACAGAAGCTGCTTTCCTGCATTTACCGCACGGGAGAACGTTTCGGACAGGCCTATGT
CATCAGCGTATTGCTGGGCGCGCAGGATGAACGGATTACAAAGTTCGGGCACGATAGCATCACGACTTACGGGATCGGCA
AGGAACACGACAATCGCACCTGGCGGGCCATTCTGCGTCAGCTGGTGGCGTTGCGCCTGATTGAGGTGGATCTGTCCGGG
CATGGCGGATTGTCCATTTCAGAGAACGGGAGGCGGTTCCTGCGCGAAAAGCCTTCCCTGATGCTGAGGATACCGTCAGC
GCCGCGGTCGACACGACGGGATGCGCCACGGAATGCAATGTCGACGGCTCTGCCGGAGGCAGACCGGGGCCTCTTTGAGG
CGCTGCGTGCCAAGCGCATGGAAATTGCCCGCGCACAGAACGTTCCGCCCTATGTGATCTTTCACGACAAGACCCTCATT
GAACTCGCGGCGGCGAGACCTGCCTCTGCGAAGGAGATGGCGCAGATCGCCGGCGTTGGGCAAACCAAGCTGGAGCGATA
CGGTCCCGCCTTTCTTGACACGATAATGCAGCACGCTGCTGGTGAATAA

Upstream 100 bases:

>100_bases
CTCCAGAAACGGTAACAGCCCTCAGAAAAGCCATCTCCGGCATTGCCAGGATGCCTGAAATGGACATGATGCGCCATCAA
GCCCAGCATGGAAAAACGAC

Downstream 100 bases:

>100_bases
TCGCCAGATGAGCCAAAAAAGAGCCGGGTAAGGAACCCGGTAAAGGCTCTCAGCCCGTCGTATCCTTGAACAGAACGTTC
TGATCGATGAGATAACGCGA

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MNADPLNILKAVYGYDAFRGRQGEIIQHVVAGNNAFVLMPTGGGKSLCYQIPALAREGMGLVVSPLIALMVDQVAALRQA
GVRAEALNSDLSPEERRTLWRDVRAGNVDILYAAPETLLKPDVLDALQSIDLSLIAVDEAHCLSQWGHDFRPPYRQLDML
IARFPNTPRMALTATADEPTRAEILGHLAIDEADAFIAGFDRPNIRYAIMEKDNPRTQLKRFLNGRENESGIVYCLSKRK
VEETAAWLREEGRDALPYHAGMDKAAREENQTRFQHGEAVIIVATVAFGMGIDKPDVRFVVHIDLPGSIEAYYQETGRAG
RDGLPSDVLMLYGYEDIALRNRFIEESDAADQRKYMERQKLDALLGLAETAGCRRQVLLSYFGDRCEPCGNCDTCSSPPD
LFEGAIAAQKLLSCIYRTGERFGQAYVISVLLGAQDERITKFGHDSITTYGIGKEHDNRTWRAILRQLVALRLIEVDLSG
HGGLSISENGRRFLREKPSLMLRIPSAPRSTRRDAPRNAMSTALPEADRGLFEALRAKRMEIARAQNVPPYVIFHDKTLI
ELAAARPASAKEMAQIAGVGQTKLERYGPAFLDTIMQHAAGE

Sequences:

>Translated_602_residues
MNADPLNILKAVYGYDAFRGRQGEIIQHVVAGNNAFVLMPTGGGKSLCYQIPALAREGMGLVVSPLIALMVDQVAALRQA
GVRAEALNSDLSPEERRTLWRDVRAGNVDILYAAPETLLKPDVLDALQSIDLSLIAVDEAHCLSQWGHDFRPPYRQLDML
IARFPNTPRMALTATADEPTRAEILGHLAIDEADAFIAGFDRPNIRYAIMEKDNPRTQLKRFLNGRENESGIVYCLSKRK
VEETAAWLREEGRDALPYHAGMDKAAREENQTRFQHGEAVIIVATVAFGMGIDKPDVRFVVHIDLPGSIEAYYQETGRAG
RDGLPSDVLMLYGYEDIALRNRFIEESDAADQRKYMERQKLDALLGLAETAGCRRQVLLSYFGDRCEPCGNCDTCSSPPD
LFEGAIAAQKLLSCIYRTGERFGQAYVISVLLGAQDERITKFGHDSITTYGIGKEHDNRTWRAILRQLVALRLIEVDLSG
HGGLSISENGRRFLREKPSLMLRIPSAPRSTRRDAPRNAMSTALPEADRGLFEALRAKRMEIARAQNVPPYVIFHDKTLI
ELAAARPASAKEMAQIAGVGQTKLERYGPAFLDTIMQHAAGE
>Mature_602_residues
MNADPLNILKAVYGYDAFRGRQGEIIQHVVAGNNAFVLMPTGGGKSLCYQIPALAREGMGLVVSPLIALMVDQVAALRQA
GVRAEALNSDLSPEERRTLWRDVRAGNVDILYAAPETLLKPDVLDALQSIDLSLIAVDEAHCLSQWGHDFRPPYRQLDML
IARFPNTPRMALTATADEPTRAEILGHLAIDEADAFIAGFDRPNIRYAIMEKDNPRTQLKRFLNGRENESGIVYCLSKRK
VEETAAWLREEGRDALPYHAGMDKAAREENQTRFQHGEAVIIVATVAFGMGIDKPDVRFVVHIDLPGSIEAYYQETGRAG
RDGLPSDVLMLYGYEDIALRNRFIEESDAADQRKYMERQKLDALLGLAETAGCRRQVLLSYFGDRCEPCGNCDTCSSPPD
LFEGAIAAQKLLSCIYRTGERFGQAYVISVLLGAQDERITKFGHDSITTYGIGKEHDNRTWRAILRQLVALRLIEVDLSG
HGGLSISENGRRFLREKPSLMLRIPSAPRSTRRDAPRNAMSTALPEADRGLFEALRAKRMEIARAQNVPPYVIFHDKTLI
ELAAARPASAKEMAQIAGVGQTKLERYGPAFLDTIMQHAAGE

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=637, Percent_Identity=30.7692307692308, Blast_Score=308, Evalue=7e-84,
Organism=Homo sapiens, GI14591902, Length=404, Percent_Identity=37.3762376237624, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI14591904, Length=404, Percent_Identity=37.3762376237624, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI110735439, Length=692, Percent_Identity=30.0578034682081, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI169218196, Length=542, Percent_Identity=33.7638376383764, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI148612816, Length=420, Percent_Identity=39.5238095238095, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI51242943, Length=393, Percent_Identity=39.440203562341, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI51242947, Length=393, Percent_Identity=39.440203562341, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI284005309, Length=435, Percent_Identity=34.7126436781609, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI4758138, Length=317, Percent_Identity=28.391167192429, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI48994977, Length=600, Percent_Identity=47.1666666666667, Blast_Score=553, Evalue=1e-158,
Organism=Escherichia coli, GI87082221, Length=331, Percent_Identity=25.0755287009063, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787605, Length=333, Percent_Identity=26.7267267267267, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788930, Length=131, Percent_Identity=32.0610687022901, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=500, Percent_Identity=36.6, Blast_Score=310, Evalue=1e-84,
Organism=Caenorhabditis elegans, GI32564293, Length=677, Percent_Identity=32.4963072378139, Blast_Score=295, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI71987997, Length=408, Percent_Identity=38.9705882352941, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71987993, Length=408, Percent_Identity=38.9705882352941, Blast_Score=280, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17552866, Length=434, Percent_Identity=35.2534562211982, Blast_Score=239, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI115533224, Length=379, Percent_Identity=24.802110817942, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995718, Length=344, Percent_Identity=25.8720930232558, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17510307, Length=310, Percent_Identity=26.4516129032258, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17510309, Length=310, Percent_Identity=26.4516129032258, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17555296, Length=336, Percent_Identity=24.702380952381, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71995514, Length=313, Percent_Identity=26.8370607028754, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71999646, Length=337, Percent_Identity=23.4421364985163, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71999644, Length=337, Percent_Identity=23.4421364985163, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=532, Percent_Identity=35.3383458646617, Blast_Score=314, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6324217, Length=382, Percent_Identity=23.2984293193717, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321360, Length=360, Percent_Identity=22.7777777777778, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323947, Length=340, Percent_Identity=24.1176470588235, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320041, Length=343, Percent_Identity=21.865889212828, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646066, Length=631, Percent_Identity=33.7559429477021, Blast_Score=344, Evalue=1e-94,
Organism=Drosophila melanogaster, GI24664226, Length=447, Percent_Identity=36.0178970917226, Blast_Score=258, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24664230, Length=428, Percent_Identity=36.6822429906542, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI62472181, Length=428, Percent_Identity=36.6822429906542, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI21358123, Length=348, Percent_Identity=35.632183908046, Blast_Score=204, Evalue=1e-52,
Organism=Drosophila melanogaster, GI28575014, Length=348, Percent_Identity=22.1264367816092, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28574962, Length=346, Percent_Identity=24.5664739884393, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66794; Mature: 66794

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNADPLNILKAVYGYDAFRGRQGEIIQHVVAGNNAFVLMPTGGGKSLCYQIPALAREGMG
CCCCHHHHHHHHHCCHHHCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHCHHHHHCCCC
LVVSPLIALMVDQVAALRQAGVRAEALNSDLSPEERRTLWRDVRAGNVDILYAAPETLLK
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHCC
PDVLDALQSIDLSLIAVDEAHCLSQWGHDFRPPYRQLDMLIARFPNTPRMALTATADEPT
CHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCH
RAEILGHLAIDEADAFIAGFDRPNIRYAIMEKDNPRTQLKRFLNGRENESGIVYCLSKRK
HHHHHHHHHHCCCCHHEEECCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCEEEEECHHH
VEETAAWLREEGRDALPYHAGMDKAAREENQTRFQHGEAVIIVATVAFGMGIDKPDVRFV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCCEEEE
VHIDLPGSIEAYYQETGRAGRDGLPSDVLMLYGYEDIALRNRFIEESDAADQRKYMERQK
EEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHH
LDALLGLAETAGCRRQVLLSYFGDRCEPCGNCDTCSSPPDLFEGAIAAQKLLSCIYRTGE
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RFGQAYVISVLLGAQDERITKFGHDSITTYGIGKEHDNRTWRAILRQLVALRLIEVDLSG
HHCHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHEEEECC
HGGLSISENGRRFLREKPSLMLRIPSAPRSTRRDAPRNAMSTALPEADRGLFEALRAKRM
CCCCEECCCHHHHHHCCCCEEEECCCCCCHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
EIARAQNVPPYVIFHDKTLIELAAARPASAKEMAQIAGVGQTKLERYGPAFLDTIMQHAA
HHHHHCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHC
GE
CC
>Mature Secondary Structure
MNADPLNILKAVYGYDAFRGRQGEIIQHVVAGNNAFVLMPTGGGKSLCYQIPALAREGMG
CCCCHHHHHHHHHCCHHHCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHCHHHHHCCCC
LVVSPLIALMVDQVAALRQAGVRAEALNSDLSPEERRTLWRDVRAGNVDILYAAPETLLK
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHCC
PDVLDALQSIDLSLIAVDEAHCLSQWGHDFRPPYRQLDMLIARFPNTPRMALTATADEPT
CHHHHHHHHCCEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCH
RAEILGHLAIDEADAFIAGFDRPNIRYAIMEKDNPRTQLKRFLNGRENESGIVYCLSKRK
HHHHHHHHHHCCCCHHEEECCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCEEEEECHHH
VEETAAWLREEGRDALPYHAGMDKAAREENQTRFQHGEAVIIVATVAFGMGIDKPDVRFV
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEHHHHCCCCCCCEEEE
VHIDLPGSIEAYYQETGRAGRDGLPSDVLMLYGYEDIALRNRFIEESDAADQRKYMERQK
EEEECCCCHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCHHHHHHHHHHH
LDALLGLAETAGCRRQVLLSYFGDRCEPCGNCDTCSSPPDLFEGAIAAQKLLSCIYRTGE
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RFGQAYVISVLLGAQDERITKFGHDSITTYGIGKEHDNRTWRAILRQLVALRLIEVDLSG
HHCHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHEEEECC
HGGLSISENGRRFLREKPSLMLRIPSAPRSTRRDAPRNAMSTALPEADRGLFEALRAKRM
CCCCEECCCHHHHHHCCCCEEEECCCCCCHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
EIARAQNVPPYVIFHDKTLIELAAARPASAKEMAQIAGVGQTKLERYGPAFLDTIMQHAA
HHHHHCCCCCEEEECCCHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHCHHHHHHHHHHHC
GE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]