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The map label for this gene is actR [H]

Identifier: 15887408

GI number: 15887408

Start: 51594

End: 52181

Strand: Reverse

Name: actR [H]

Synonym: Atu0050

Alternate gene names: 15887408

Gene position: 52181-51594 (Counterclockwise)

Preceding gene: 159184141

Following gene: 159184139

Centisome position: 1.84

GC content: 60.2

Gene sequence:

>588_bases
ATGAAGATTGAAGACCAGACCCCAGCCACCAGCGAACCGGTGGACGATATCGATCCGATCGGACCCGACAGATCGCTGCT
GATCGTCGACGATGACGGCCCGTTTCTGCGCCGGCTTGCCCGGGCCATGGAAACGCGCGGCTTTGCCGTCGATACTGCCG
AGACAGTGAGCGAGGGCATTGCCCGCTCCAAGGCCGCGCCGCCGAAATATGCGGTCGTCGATTTGAGGCTTGCTGACGGC
AACGGGCTGGAAGTGATCGAAGCCATCAGGCAGAACCGGGACGATACACAGATCGTCGTTTTGACCGGCTACGGCAATAT
CGCCACCGCCGTGACTGCCGTGAAGCTCGGTGCGCTGGACTATCTCGCCAAACCCGCCGATGCGGACGATGTCTTTAATG
CTCTGACACAGCGCAAGGGTGAAAAGACCGAGGTTCCCGAAAACCCCATGTCGGCAGACCGCGTGCGCTGGGAGCATATT
CAGCGGGTTTATGAAATGTGCGAACGCAATGTTTCGGAAACGGCGCGTCGGCTCAACATGCATCGGCGCACCCTGCAGCG
CATTCTCGCGAAACGCGCTCCGAAGTGA

Upstream 100 bases:

>100_bases
CTGATGGACGATAAAAGAAGCCGTTGACTTTACCATCCACGTTGAAGCGGCGATAAGAAGAAGAAAATCAAGCCGATGAA
GTTGCCGGAAGGCCGGAAAC

Downstream 100 bases:

>100_bases
AGCATTTCCAGTAAAAGTGCGCAATGGTTTTACGTCCGGATAATGGGCTGGAACCGAACGCTATTCCCCGAAACTGCGCC
CGGTCGTCCATTCAGCCAAC

Product: two component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKIEDQTPATSEPVDDIDPIGPDRSLLIVDDDGPFLRRLARAMETRGFAVDTAETVSEGIARSKAAPPKYAVVDLRLADG
NGLEVIEAIRQNRDDTQIVVLTGYGNIATAVTAVKLGALDYLAKPADADDVFNALTQRKGEKTEVPENPMSADRVRWEHI
QRVYEMCERNVSETARRLNMHRRTLQRILAKRAPK

Sequences:

>Translated_195_residues
MKIEDQTPATSEPVDDIDPIGPDRSLLIVDDDGPFLRRLARAMETRGFAVDTAETVSEGIARSKAAPPKYAVVDLRLADG
NGLEVIEAIRQNRDDTQIVVLTGYGNIATAVTAVKLGALDYLAKPADADDVFNALTQRKGEKTEVPENPMSADRVRWEHI
QRVYEMCERNVSETARRLNMHRRTLQRILAKRAPK
>Mature_195_residues
MKIEDQTPATSEPVDDIDPIGPDRSLLIVDDDGPFLRRLARAMETRGFAVDTAETVSEGIARSKAAPPKYAVVDLRLADG
NGLEVIEAIRQNRDDTQIVVLTGYGNIATAVTAVKLGALDYLAKPADADDVFNALTQRKGEKTEVPENPMSADRVRWEHI
QRVYEMCERNVSETARRLNMHRRTLQRILAKRAPK

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=113, Percent_Identity=30.0884955752212, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788905, Length=110, Percent_Identity=30.9090909090909, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21695; Mature: 21695

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIEDQTPATSEPVDDIDPIGPDRSLLIVDDDGPFLRRLARAMETRGFAVDTAETVSEGI
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
ARSKAAPPKYAVVDLRLADGNGLEVIEAIRQNRDDTQIVVLTGYGNIATAVTAVKLGALD
HHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
YLAKPADADDVFNALTQRKGEKTEVPENPMSADRVRWEHIQRVYEMCERNVSETARRLNM
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HRRTLQRILAKRAPK
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIEDQTPATSEPVDDIDPIGPDRSLLIVDDDGPFLRRLARAMETRGFAVDTAETVSEGI
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
ARSKAAPPKYAVVDLRLADGNGLEVIEAIRQNRDDTQIVVLTGYGNIATAVTAVKLGALD
HHHCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
YLAKPADADDVFNALTQRKGEKTEVPENPMSADRVRWEHIQRVYEMCERNVSETARRLNM
HHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HRRTLQRILAKRAPK
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]