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The map label for this gene is apeA [H]

Identifier: 239618510

GI number: 239618510

Start: 2280496

End: 2281902

Strand: Direct

Name: apeA [H]

Synonym: Kole_2151

Alternate gene names: 239618510

Gene position: 2280496-2281902 (Clockwise)

Preceding gene: 239618502

Following gene: 239618511

Centisome position: 99.06

GC content: 42.86

Gene sequence:

>1407_bases
GTGAATGTGAATAGTAAAGACGAGCTCGTATTTAAACACAAAACAGCATGGAAAGATTTAAAAAGAGCTTCTATTGAGGA
GTATTCTGGAGAATATCTTGCCTTCTTAAAGGAAGGATTAACCGAAAGAAAGGTTGTGAATTATTTAGTTGAATACCTTA
GAGATAGAGGCTTTCTTTCGTTGGATGAACTTGAAGAAAAACCAGAAAAACTCTCTGGCGTTACCGGGGTTTATAACTCA
AGGTCGGGCAAAACCCTGGTTGCGTTGCGCCTCGCTGAGGATTTTGAGAACGGATTCAGATTTGTGGGAGCTCATGCCGA
CGCACCAAGACTTGATTTGAAACCATTACCGGTGGTTGAAAAACAGGGACTTGTCCTTCTAAAAACCCACTATTACGGCG
GCGTCAAAAAATATCAGTGGTTGAATATTCCTCTTGCGCTTGTTGGGGTCGTGGTGAAATCGAATGGCGATGTTGTAGAG
ATTTCTATAGGAACAGAACCGGGTGACCCGGTGTTCGTTATAAGTGATCTTTTGCCTCATCTTGATAGGCGAAAAGGCGA
TATAAATGATGTTTTCAAAGGAAAGGATTTAAACGCGTTAGCTGCTTCCATACCGATAGATCTGGATAAGGATTCGAAAG
AATCTGTGAAACTCCATTTTCTAAAACTCTTAAACAACAAATATGGTTTAACCGAGGAAGATTTTATCAGTGCCGAACTC
CAGTTGGTTCCAGCCATTGAGCCGAGGGAAATTGGGCTGGACAGGTCCATGATTGCTGGATACGGCCACGACGATAGGGT
TTGTTCATTTGCAGCAATCACAGCTCTGGCTGATTCGAAGGAATTAAGAAAGAATGCCTGTGTCCTTATCTTCGATAAAG
AAGAGATAGGAAGCGACGGTTTAACGGGAGCTAAAGGAAGTTTCTGGATAAACACCCTCGTTAGAGTGGCGAGGTTGTTG
AAAGCGTCTGATCCAGTTATGACGGTAAATTTAGCCCTTGAAAAGTCCTATATGTTATCCGGAGATGTTTCTGCTGCCAT
TAATCCAATGTTTGCAGATGTTCACGATGTGGAAAACGCTCCACGGCTGGGTTATGGAATAGTTCTGATGAAATATACAG
GACGCGGCGGAAAATATGGTACCAGTGACGCCAGTGCTGAATTCGTCGCAAAGGTGAGAAAGATACTAAACGAAAATGAA
ATTCACTGGCAAACAGCGATTCTCGGTGAAGTAGATCAGGGTGGCGGTGGAACGATTGCCAAATTTTTTGCAGAAAAAGG
TATAGAGGTCATTGATGCAGGCCCGGCGGTTCTTGGAATGCATTCACCCTTTGAAATAATCTCAAAAGCTGATCTCTATG
AAACATACAGAGCGTACAAAGCCTTTCTGGAGGGAAAGGATGAATAA

Upstream 100 bases:

>100_bases
TCCCCCTGTCATGAATTTTGACACCACTTTTGCTGTTACGGTTCATACTAATTATACTATAAAGAATTCTTATCCTCTGA
TAGAATATTACCGGGGAGGT

Downstream 100 bases:

>100_bases
TTGTAAACCGGAAGTTGTAGCGGCAAAAATAATCGAGCTTTTTCCGCGGATTCATCAGGACAGCGATCCTTACAGGGTCC
TGGTTTCCACTGTGTTGAGT

Product: peptidase M18 aminopeptidase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNVNSKDELVFKHKTAWKDLKRASIEEYSGEYLAFLKEGLTERKVVNYLVEYLRDRGFLSLDELEEKPEKLSGVTGVYNS
RSGKTLVALRLAEDFENGFRFVGAHADAPRLDLKPLPVVEKQGLVLLKTHYYGGVKKYQWLNIPLALVGVVVKSNGDVVE
ISIGTEPGDPVFVISDLLPHLDRRKGDINDVFKGKDLNALAASIPIDLDKDSKESVKLHFLKLLNNKYGLTEEDFISAEL
QLVPAIEPREIGLDRSMIAGYGHDDRVCSFAAITALADSKELRKNACVLIFDKEEIGSDGLTGAKGSFWINTLVRVARLL
KASDPVMTVNLALEKSYMLSGDVSAAINPMFADVHDVENAPRLGYGIVLMKYTGRGGKYGTSDASAEFVAKVRKILNENE
IHWQTAILGEVDQGGGGTIAKFFAEKGIEVIDAGPAVLGMHSPFEIISKADLYETYRAYKAFLEGKDE

Sequences:

>Translated_468_residues
MNVNSKDELVFKHKTAWKDLKRASIEEYSGEYLAFLKEGLTERKVVNYLVEYLRDRGFLSLDELEEKPEKLSGVTGVYNS
RSGKTLVALRLAEDFENGFRFVGAHADAPRLDLKPLPVVEKQGLVLLKTHYYGGVKKYQWLNIPLALVGVVVKSNGDVVE
ISIGTEPGDPVFVISDLLPHLDRRKGDINDVFKGKDLNALAASIPIDLDKDSKESVKLHFLKLLNNKYGLTEEDFISAEL
QLVPAIEPREIGLDRSMIAGYGHDDRVCSFAAITALADSKELRKNACVLIFDKEEIGSDGLTGAKGSFWINTLVRVARLL
KASDPVMTVNLALEKSYMLSGDVSAAINPMFADVHDVENAPRLGYGIVLMKYTGRGGKYGTSDASAEFVAKVRKILNENE
IHWQTAILGEVDQGGGGTIAKFFAEKGIEVIDAGPAVLGMHSPFEIISKADLYETYRAYKAFLEGKDE
>Mature_468_residues
MNVNSKDELVFKHKTAWKDLKRASIEEYSGEYLAFLKEGLTERKVVNYLVEYLRDRGFLSLDELEEKPEKLSGVTGVYNS
RSGKTLVALRLAEDFENGFRFVGAHADAPRLDLKPLPVVEKQGLVLLKTHYYGGVKKYQWLNIPLALVGVVVKSNGDVVE
ISIGTEPGDPVFVISDLLPHLDRRKGDINDVFKGKDLNALAASIPIDLDKDSKESVKLHFLKLLNNKYGLTEEDFISAEL
QLVPAIEPREIGLDRSMIAGYGHDDRVCSFAAITALADSKELRKNACVLIFDKEEIGSDGLTGAKGSFWINTLVRVARLL
KASDPVMTVNLALEKSYMLSGDVSAAINPMFADVHDVENAPRLGYGIVLMKYTGRGGKYGTSDASAEFVAKVRKILNENE
IHWQTAILGEVDQGGGGTIAKFFAEKGIEVIDAGPAVLGMHSPFEIISKADLYETYRAYKAFLEGKDE

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=478, Percent_Identity=26.1506276150628, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17552916, Length=463, Percent_Identity=23.7580993520518, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321905, Length=476, Percent_Identity=26.2605042016807, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322746, Length=450, Percent_Identity=25.3333333333333, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51638; Mature: 51638

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVNSKDELVFKHKTAWKDLKRASIEEYSGEYLAFLKEGLTERKVVNYLVEYLRDRGFLS
CCCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCEE
LDELEEKPEKLSGVTGVYNSRSGKTLVALRLAEDFENGFRFVGAHADAPRLDLKPLPVVE
HHHHHHCHHHHCCCCCCCCCCCCCEEEEEEEHHHHCCCCEEEECCCCCCCCCCCCCCCCC
KQGLVLLKTHYYGGVKKYQWLNIPLALVGVVVKSNGDVVEISIGTEPGDPVFVISDLLPH
CCCEEEEEECCCCCCCEEEEECCCHHHEEEEEECCCCEEEEEECCCCCCCEEEHHHHHHH
LDRRKGDINDVFKGKDLNALAASIPIDLDKDSKESVKLHFLKLLNNKYGLTEEDFISAEL
HHHCCCCHHHHCCCCCCHHHHEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCEEE
QLVPAIEPREIGLDRSMIAGYGHDDRVCSFAAITALADSKELRKNACVLIFDKEEIGSDG
EEECCCCHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHCCHHHCCCCEEEEEEHHHCCCCC
LTGAKGSFWINTLVRVARLLKASDPVMTVNLALEKSYMLSGDVSAAINPMFADVHDVENA
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEECCCHHHHCCCHHHHHHHCCCC
PRLGYGIVLMKYTGRGGKYGTSDASAEFVAKVRKILNENEIHWQTAILGEVDQGGGGTIA
CCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHH
KFFAEKGIEVIDAGPAVLGMHSPFEIISKADLYETYRAYKAFLEGKDE
HHHHHCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNVNSKDELVFKHKTAWKDLKRASIEEYSGEYLAFLKEGLTERKVVNYLVEYLRDRGFLS
CCCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCEE
LDELEEKPEKLSGVTGVYNSRSGKTLVALRLAEDFENGFRFVGAHADAPRLDLKPLPVVE
HHHHHHCHHHHCCCCCCCCCCCCCEEEEEEEHHHHCCCCEEEECCCCCCCCCCCCCCCCC
KQGLVLLKTHYYGGVKKYQWLNIPLALVGVVVKSNGDVVEISIGTEPGDPVFVISDLLPH
CCCEEEEEECCCCCCCEEEEECCCHHHEEEEEECCCCEEEEEECCCCCCCEEEHHHHHHH
LDRRKGDINDVFKGKDLNALAASIPIDLDKDSKESVKLHFLKLLNNKYGLTEEDFISAEL
HHHCCCCHHHHCCCCCCHHHHEECCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHCCEEE
QLVPAIEPREIGLDRSMIAGYGHDDRVCSFAAITALADSKELRKNACVLIFDKEEIGSDG
EEECCCCHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHCCHHHCCCCEEEEEEHHHCCCCC
LTGAKGSFWINTLVRVARLLKASDPVMTVNLALEKSYMLSGDVSAAINPMFADVHDVENA
CCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEECCCHHHHCCCHHHHHHHCCCC
PRLGYGIVLMKYTGRGGKYGTSDASAEFVAKVRKILNENEIHWQTAILGEVDQGGGGTIA
CCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHH
KFFAEKGIEVIDAGPAVLGMHSPFEIISKADLYETYRAYKAFLEGKDE
HHHHHCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]