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The map label for this gene is ttdA [C]

Identifier: 239618453

GI number: 239618453

Start: 2225567

End: 2226394

Strand: Reverse

Name: ttdA [C]

Synonym: Kole_2094

Alternate gene names: 239618453

Gene position: 2226394-2225567 (Counterclockwise)

Preceding gene: 239618454

Following gene: 239618452

Centisome position: 96.71

GC content: 41.91

Gene sequence:

>828_bases
ATGATCAAAAGCTCTGAAATCATAAATGCAGTTTCTAAGTCAATTATAGAGGCAAACACGATTGCTGATCCATATGTTGT
CGAACAGGCTTCGCAGTATAGCGGCCCATTTTCTGAGATAATAAAAGAGAATTTCAAACTTGCTGCTGAAAAAGGGCTCC
CTATCTGTCAGGACACGGGAATGCTTGAATTTTTTGTGTTTTTGGGACATGAAGTCTGCCTCGAGGAACCGATCTGTGCT
TCCCTTGAACGAGCTGTAAGAGAAGTTTATACCACTCAGCCATACAGATATTCCATTGTATCCGATCCTCTTTATGAACG
AAAGAACACTGGCGACAACACACCGGTTGTCTGCCATGTATTCCACACGAAAGGAAGACATATGGAAGTTAGGTTCCTCA
TTAAGGGCGGAGGAAGCGAAAATCTGAGCGCTTTGTTTATGTTAAAACCCTCCGCTGAACCAGAGGAAATTAAAAATGCT
GTTGTAAATCATATAAAAGAACTGGGACCGAATGCCTGTCCACCCTTGAATATAGGTATAGGAATTGGAGGTACGGCTGA
TAAAGCTATGCTCCTTTCGAAACTCGCTCTAACCAACCCTTTCAACCGGAAAAATCCGAACGAAAAATATAACGAACTTG
AAAATGAGATTCTGGAAGATGTAAATGCTTTAAAAATTGGTTACCAGGGATTGGGGAATGGTATCTCTGCCTATTCCGTG
AGTATCGAGTACTATCCCACGCACATAGCGACGCTGCCTGTTGCGGTTTCTGTAGATTGCTTCATTTGCAGGAAAGGGAG
GATTGTTTTTGAAGATAAAGGAACTTAA

Upstream 100 bases:

>100_bases
ACTCTGCTGAACGATTTTGCTTGATACCGAGGTGCCAATGAACCCCTTTTAACCTGTTATATTGGATGTGAATACTCTAA
AGATATAGATAGGAGCGAGT

Downstream 100 bases:

>100_bases
GGTTGGAAGTGAAATTGAGTACACCGGCGAACTCATTGTTATGCGCGATGCCGCACAAAAGAGAACAAAAACGATACTGG
AAGGAAATCTTCCGCTTCCT

Product: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MIKSSEIINAVSKSIIEANTIADPYVVEQASQYSGPFSEIIKENFKLAAEKGLPICQDTGMLEFFVFLGHEVCLEEPICA
SLERAVREVYTTQPYRYSIVSDPLYERKNTGDNTPVVCHVFHTKGRHMEVRFLIKGGGSENLSALFMLKPSAEPEEIKNA
VVNHIKELGPNACPPLNIGIGIGGTADKAMLLSKLALTNPFNRKNPNEKYNELENEILEDVNALKIGYQGLGNGISAYSV
SIEYYPTHIATLPVAVSVDCFICRKGRIVFEDKGT

Sequences:

>Translated_275_residues
MIKSSEIINAVSKSIIEANTIADPYVVEQASQYSGPFSEIIKENFKLAAEKGLPICQDTGMLEFFVFLGHEVCLEEPICA
SLERAVREVYTTQPYRYSIVSDPLYERKNTGDNTPVVCHVFHTKGRHMEVRFLIKGGGSENLSALFMLKPSAEPEEIKNA
VVNHIKELGPNACPPLNIGIGIGGTADKAMLLSKLALTNPFNRKNPNEKYNELENEILEDVNALKIGYQGLGNGISAYSV
SIEYYPTHIATLPVAVSVDCFICRKGRIVFEDKGT
>Mature_275_residues
MIKSSEIINAVSKSIIEANTIADPYVVEQASQYSGPFSEIIKENFKLAAEKGLPICQDTGMLEFFVFLGHEVCLEEPICA
SLERAVREVYTTQPYRYSIVSDPLYERKNTGDNTPVVCHVFHTKGRHMEVRFLIKGGGSENLSALFMLKPSAEPEEIKNA
VVNHIKELGPNACPPLNIGIGIGGTADKAMLLSKLALTNPFNRKNPNEKYNELENEILEDVNALKIGYQGLGNGISAYSV
SIEYYPTHIATLPVAVSVDCFICRKGRIVFEDKGT

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=229, Percent_Identity=34.061135371179, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787897, Length=232, Percent_Identity=31.4655172413793, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790564, Length=231, Percent_Identity=30.7359307359307, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30332; Mature: 30332

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKSSEIINAVSKSIIEANTIADPYVVEQASQYSGPFSEIIKENFKLAAEKGLPICQDTG
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
MLEFFVFLGHEVCLEEPICASLERAVREVYTTQPYRYSIVSDPLYERKNTGDNTPVVCHV
HHHHHHHHCHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCEEEEE
FHTKGRHMEVRFLIKGGGSENLSALFMLKPSAEPEEIKNAVVNHIKELGPNACPPLNIGI
EECCCCEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
GIGGTADKAMLLSKLALTNPFNRKNPNEKYNELENEILEDVNALKIGYQGLGNGISAYSV
ECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEE
SIEYYPTHIATLPVAVSVDCFICRKGRIVFEDKGT
EEEEECCCCEECCEEEEEEEEEEECCEEEEECCCC
>Mature Secondary Structure
MIKSSEIINAVSKSIIEANTIADPYVVEQASQYSGPFSEIIKENFKLAAEKGLPICQDTG
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCC
MLEFFVFLGHEVCLEEPICASLERAVREVYTTQPYRYSIVSDPLYERKNTGDNTPVVCHV
HHHHHHHHCHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCEEEEE
FHTKGRHMEVRFLIKGGGSENLSALFMLKPSAEPEEIKNAVVNHIKELGPNACPPLNIGI
EECCCCEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEE
GIGGTADKAMLLSKLALTNPFNRKNPNEKYNELENEILEDVNALKIGYQGLGNGISAYSV
ECCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEE
SIEYYPTHIATLPVAVSVDCFICRKGRIVFEDKGT
EEEEECCCCEECCEEEEEEEEEEECCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]