Click here to switch to the map view.

The map label for this gene is pucD [H]

Identifier: 239618446

GI number: 239618446

Start: 2215558

End: 2217858

Strand: Reverse

Name: pucD [H]

Synonym: Kole_2087

Alternate gene names: 239618446

Gene position: 2217858-2215558 (Counterclockwise)

Preceding gene: 239618447

Following gene: 239618445

Centisome position: 96.34

GC content: 43.59

Gene sequence:

>2301_bases
ATGAGGACAACAGTAAAACTCAGGAACGTTATAGGAAAGAAAGTCAAAAGGGTTGATGCACTGCCTAAAGTAACCGGGCA
GGCTAAATTTGCAGCTGATATGTACTTCAACAGGATGGTTTACTGCTCTCTCGTACTTGCCAGAAAACCCCACGGAGTTC
TGAAGGAAATAGAATTCTCGGAAGCGTTGAAAATTCCCGATGTTATTGGTATTTACACTGCAAAAGATGTTCCTGGTGAA
AACCAACTCGGTGAAGTTGTTAAAGACATGCCCTGTCTCGTTCCAGTAGGAGGAAAAATAAGGTATTATGGCGACGTTGT
TGCTGTGGTAGCTGCTGAAAGTCAGGAAGCAGCTGATGAAGCTGCAAAACGTGTAAAACTGTCCATAGAGGAATTGCCAC
CTATTTTTAGCATTGAGGAGGCGTTGAAAGACGAAATAAAGATACACGAGCCAACGAATGTCCCGATTCACAAGAAAATA
AGGAAAGGCGACGTCGAAAAAGGATTTGCAGAATCCGAATTCATTTTCGAAGACGACTTCCACGCCGATTATCAGGAACA
AGCCTATTTAGAACCTCAAGGGGTTGTCGTTTTGCCAGATATTGATTACGGTTATACCGTTTATGGAACAATGCAGTGTC
CATATTATGTTCAAAACAGTGTTGCACATATTCTTGGCATTGATTTAAACAAGGTGCGTGTGATTCAAACAGAGACCGGT
GGCGGATTCGGAGGAAAGGAAGATGTACCTTCTTATGTCGCTAGTTACGCCGCTGTTGCTGCGTACAATACAGGCAGGCC
TGCCAAACTCATATACAGCAGAGAAGTTGATATACAAACAACATCTAAACGCCATCCAATTACTTCTCACTACAAAATAG
GTGTGGACAAGAGCGGAAAGTTAAAATCAATAGAGATCAAGGCCTACATGGATATGGGAGCCTACGCTACCCTATCACCT
ATCGTAATGTTCAGAACGCTTGTTCATGCAGCTGGTAGTTATGAGATACCAAATGTTAAAGTGGATGTTTATGGTGTCTA
CACCAACAAGGTTCCGCCAGGTGCTTTTAGAGGCTTTGGAAGCCCACAGGTTCTTTTTGCCGTTGAATCCATGATCGATG
AGATCTCTCTAAAGCTAGGCATAGACCCAATTGAGTTCAGGTTGAAAAACACTCTTCGTGTTGGAAGCAGAACGGCCACA
AATCATCTGCTCACGGAAAGTGTTGGGGCGGTCCAAACTCTGGAAAATGTCAGAACAATCGCTGATTGGGAAAATCTGAA
GAAGGAAGTAGAAGAATTCAACAAACAGAATAGTTTCAAAAAACGCGGACTTGGCGTTTCACATATAATCTATGGGGTCA
GCCTCGGCGCTGCCGGGCAGCACTTAGATGCTTCAGGAGCACACATACAGGTGAACAAGGATGGAACCATAGACGTAAGA
ATAGGCGGTACAGAAATGGGACAGGGAGCGAAAACAGTGATTGCTATGCTCGCTGCGGAAGAGCTCGGACAAAAACTGGA
AAAGATCAATGTTCATCAACCTGATACCGCTTTCGTTCCCGATAGTGGGCCAACCGTCGCTTCAAGAACCACTCTCTATT
CCGGAAATGCTGTGAGAATAGCTGCGAGAGAATTAAGAAAAAGATTTGTTCAACTCTTCGCCGAGATCTTTGATACCGAT
CCCGAAGATGTTAGCTGGGAAAACGGCCGTTATTTTGACTCCAAAGGAAATGAGCTCAGTTTTGATGAACTTGTGGAAAA
TGCTTATATGAAAAATGTAAAATTGAATGAAACGGGATGGTACGAGACCCCAAAACTTGAGTGGGATCATGAAACCGGGC
AGGGTGAAGCCTATGTGACCTATTCGTATGCCAGCCAGATAGTTCTGGTTGAAGTTGACATGTTGACAGGCTTGACGAGA
GTTGTAAAAGGATTTACAAGTCATGATGTCGGTAAAGCGTTGAACCCGGAAGGACTCATTGGCCAGATTCAGGGTGGTTT
TGTTCAGGGAATGGGTTACGCTCTGTATGAGCAAATTAAGATGGATCGTGGCAAAATTGTCACCGATAATTTCAATACTT
ATATAATTCCGACAATACATGAAATCCCTGAAGAGCTTAAAATAGATATAGTCGAAGATGAATACTCTTCCGGTCCGTAC
GGTGCCAAAGGAATTGGTGAACCATCACTGATGCCAACACCTGCTGCCATAGCTAACGGTATTTCACGTGCGATTGGTAA
GAGAGTAAAAAGAATACCAGCGACTGCCGAGTATATATTAAAACTCATCAAGGAGGCATGA

Upstream 100 bases:

>100_bases
CTTTCGGTGATACCGGAATTGAGAATAACAAATCAGGGGCTTGTTGATGTTATCAACAATAACTTTGTATCACTGTTCAT
CGGAAAGGAAGGCTGACATT

Downstream 100 bases:

>100_bases
ACGAATGAAGAAGCTTGTGCTTGGTCCAACATTTGAAGAAATGTTGCATCCCGATAAGATCGACCCAAAAATCAGAAAGA
AAGCATGGGAAATGAAAAAA

Product: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding

Products: NA

Alternate protein names: XDHase subunit D [H]

Number of amino acids: Translated: 766; Mature: 766

Protein sequence:

>766_residues
MRTTVKLRNVIGKKVKRVDALPKVTGQAKFAADMYFNRMVYCSLVLARKPHGVLKEIEFSEALKIPDVIGIYTAKDVPGE
NQLGEVVKDMPCLVPVGGKIRYYGDVVAVVAAESQEAADEAAKRVKLSIEELPPIFSIEEALKDEIKIHEPTNVPIHKKI
RKGDVEKGFAESEFIFEDDFHADYQEQAYLEPQGVVVLPDIDYGYTVYGTMQCPYYVQNSVAHILGIDLNKVRVIQTETG
GGFGGKEDVPSYVASYAAVAAYNTGRPAKLIYSREVDIQTTSKRHPITSHYKIGVDKSGKLKSIEIKAYMDMGAYATLSP
IVMFRTLVHAAGSYEIPNVKVDVYGVYTNKVPPGAFRGFGSPQVLFAVESMIDEISLKLGIDPIEFRLKNTLRVGSRTAT
NHLLTESVGAVQTLENVRTIADWENLKKEVEEFNKQNSFKKRGLGVSHIIYGVSLGAAGQHLDASGAHIQVNKDGTIDVR
IGGTEMGQGAKTVIAMLAAEELGQKLEKINVHQPDTAFVPDSGPTVASRTTLYSGNAVRIAARELRKRFVQLFAEIFDTD
PEDVSWENGRYFDSKGNELSFDELVENAYMKNVKLNETGWYETPKLEWDHETGQGEAYVTYSYASQIVLVEVDMLTGLTR
VVKGFTSHDVGKALNPEGLIGQIQGGFVQGMGYALYEQIKMDRGKIVTDNFNTYIIPTIHEIPEELKIDIVEDEYSSGPY
GAKGIGEPSLMPTPAAIANGISRAIGKRVKRIPATAEYILKLIKEA

Sequences:

>Translated_766_residues
MRTTVKLRNVIGKKVKRVDALPKVTGQAKFAADMYFNRMVYCSLVLARKPHGVLKEIEFSEALKIPDVIGIYTAKDVPGE
NQLGEVVKDMPCLVPVGGKIRYYGDVVAVVAAESQEAADEAAKRVKLSIEELPPIFSIEEALKDEIKIHEPTNVPIHKKI
RKGDVEKGFAESEFIFEDDFHADYQEQAYLEPQGVVVLPDIDYGYTVYGTMQCPYYVQNSVAHILGIDLNKVRVIQTETG
GGFGGKEDVPSYVASYAAVAAYNTGRPAKLIYSREVDIQTTSKRHPITSHYKIGVDKSGKLKSIEIKAYMDMGAYATLSP
IVMFRTLVHAAGSYEIPNVKVDVYGVYTNKVPPGAFRGFGSPQVLFAVESMIDEISLKLGIDPIEFRLKNTLRVGSRTAT
NHLLTESVGAVQTLENVRTIADWENLKKEVEEFNKQNSFKKRGLGVSHIIYGVSLGAAGQHLDASGAHIQVNKDGTIDVR
IGGTEMGQGAKTVIAMLAAEELGQKLEKINVHQPDTAFVPDSGPTVASRTTLYSGNAVRIAARELRKRFVQLFAEIFDTD
PEDVSWENGRYFDSKGNELSFDELVENAYMKNVKLNETGWYETPKLEWDHETGQGEAYVTYSYASQIVLVEVDMLTGLTR
VVKGFTSHDVGKALNPEGLIGQIQGGFVQGMGYALYEQIKMDRGKIVTDNFNTYIIPTIHEIPEELKIDIVEDEYSSGPY
GAKGIGEPSLMPTPAAIANGISRAIGKRVKRIPATAEYILKLIKEA
>Mature_766_residues
MRTTVKLRNVIGKKVKRVDALPKVTGQAKFAADMYFNRMVYCSLVLARKPHGVLKEIEFSEALKIPDVIGIYTAKDVPGE
NQLGEVVKDMPCLVPVGGKIRYYGDVVAVVAAESQEAADEAAKRVKLSIEELPPIFSIEEALKDEIKIHEPTNVPIHKKI
RKGDVEKGFAESEFIFEDDFHADYQEQAYLEPQGVVVLPDIDYGYTVYGTMQCPYYVQNSVAHILGIDLNKVRVIQTETG
GGFGGKEDVPSYVASYAAVAAYNTGRPAKLIYSREVDIQTTSKRHPITSHYKIGVDKSGKLKSIEIKAYMDMGAYATLSP
IVMFRTLVHAAGSYEIPNVKVDVYGVYTNKVPPGAFRGFGSPQVLFAVESMIDEISLKLGIDPIEFRLKNTLRVGSRTAT
NHLLTESVGAVQTLENVRTIADWENLKKEVEEFNKQNSFKKRGLGVSHIIYGVSLGAAGQHLDASGAHIQVNKDGTIDVR
IGGTEMGQGAKTVIAMLAAEELGQKLEKINVHQPDTAFVPDSGPTVASRTTLYSGNAVRIAARELRKRFVQLFAEIFDTD
PEDVSWENGRYFDSKGNELSFDELVENAYMKNVKLNETGWYETPKLEWDHETGQGEAYVTYSYASQIVLVEVDMLTGLTR
VVKGFTSHDVGKALNPEGLIGQIQGGFVQGMGYALYEQIKMDRGKIVTDNFNTYIIPTIHEIPEELKIDIVEDEYSSGPY
GAKGIGEPSLMPTPAAIANGISRAIGKRVKRIPATAEYILKLIKEA

Specific function: Oxidizes hypoxanthine and xanthine to uric acid [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=769, Percent_Identity=32.5097529258778, Blast_Score=366, Evalue=1e-101,
Organism=Homo sapiens, GI71773480, Length=741, Percent_Identity=28.7449392712551, Blast_Score=296, Evalue=6e-80,
Organism=Escherichia coli, GI1789230, Length=761, Percent_Identity=29.8291721419185, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1789246, Length=813, Percent_Identity=26.6912669126691, Blast_Score=258, Evalue=9e-70,
Organism=Escherichia coli, GI1786478, Length=756, Percent_Identity=27.2486772486773, Blast_Score=183, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17540638, Length=732, Percent_Identity=31.6939890710383, Blast_Score=330, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI32566215, Length=728, Percent_Identity=26.7857142857143, Blast_Score=239, Evalue=6e-63,
Organism=Caenorhabditis elegans, GI17539860, Length=749, Percent_Identity=27.2363150867824, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI17737937, Length=729, Percent_Identity=31.9615912208505, Blast_Score=332, Evalue=7e-91,
Organism=Drosophila melanogaster, GI24647193, Length=754, Percent_Identity=28.3819628647215, Blast_Score=236, Evalue=5e-62,
Organism=Drosophila melanogaster, GI24647199, Length=751, Percent_Identity=28.2290279627164, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24647195, Length=751, Percent_Identity=25.832223701731, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24647201, Length=757, Percent_Identity=26.6842800528402, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24647197, Length=735, Percent_Identity=25.9863945578231, Blast_Score=202, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR017609 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 84487; Mature: 84487

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTTVKLRNVIGKKVKRVDALPKVTGQAKFAADMYFNRMVYCSLVLARKPHGVLKEIEFS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHH
EALKIPDVIGIYTAKDVPGENQLGEVVKDMPCLVPVGGKIRYYGDVVAVVAAESQEAADE
HHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEECCCEEEEECCEEEEEECCCHHHHHH
AAKRVKLSIEELPPIFSIEEALKDEIKIHEPTNVPIHKKIRKGDVEKGFAESEFIFEDDF
HHHHHEEEHHHCCCCHHHHHHHHHCEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEECCC
HADYQEQAYLEPQGVVVLPDIDYGYTVYGTMQCPYYVQNSVAHILGIDLNKVRVIQTETG
CCCCCHHCEECCCCEEEEECCCCCEEEEEEEECCHHHHHCHHHHEECCCCCEEEEEEECC
GGFGGKEDVPSYVASYAAVAAYNTGRPAKLIYSREVDIQTTSKRHPITSHYKIGVDKSGK
CCCCCCCHHHHHHHHHHHHEEECCCCCEEEEEEECCCEEECCCCCCCCCCEEECCCCCCC
LKSIEIKAYMDMGAYATLSPIVMFRTLVHAAGSYEIPNVKVDVYGVYTNKVPPGAFRGFG
EEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHCCCC
SPQVLFAVESMIDEISLKLGIDPIEFRLKNTLRVGSRTATNHLLTESVGAVQTLENVRTI
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADWENLKKEVEEFNKQNSFKKRGLGVSHIIYGVSLGAAGQHLDASGAHIQVNKDGTIDVR
HHHHHHHHHHHHHHHHCCHHHHCCCHHHHHEEEEECCCCCCCCCCCCEEEECCCCEEEEE
IGGTEMGQGAKTVIAMLAAEELGQKLEKINVHQPDTAFVPDSGPTVASRTTLYSGNAVRI
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCEEEECCCEEEH
AARELRKRFVQLFAEIFDTDPEDVSWENGRYFDSKGNELSFDELVENAYMKNVKLNETGW
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCEECCCCC
YETPKLEWDHETGQGEAYVTYSYASQIVLVEVDMLTGLTRVVKGFTSHDVGKALNPEGLI
CCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCE
GQIQGGFVQGMGYALYEQIKMDRGKIVTDNFNTYIIPTIHEIPEELKIDIVEDEYSSGPY
EEECCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCHHHCCHHHEEEEEECCCCCCCC
GAKGIGEPSLMPTPAAIANGISRAIGKRVKRIPATAEYILKLIKEA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRTTVKLRNVIGKKVKRVDALPKVTGQAKFAADMYFNRMVYCSLVLARKPHGVLKEIEFS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHH
EALKIPDVIGIYTAKDVPGENQLGEVVKDMPCLVPVGGKIRYYGDVVAVVAAESQEAADE
HHCCCCCEEEEEEECCCCCCHHHHHHHHCCCCEEECCCEEEEECCEEEEEECCCHHHHHH
AAKRVKLSIEELPPIFSIEEALKDEIKIHEPTNVPIHKKIRKGDVEKGFAESEFIFEDDF
HHHHHEEEHHHCCCCHHHHHHHHHCEEEECCCCCCHHHHHHCCCCCCCCCCCCCEEECCC
HADYQEQAYLEPQGVVVLPDIDYGYTVYGTMQCPYYVQNSVAHILGIDLNKVRVIQTETG
CCCCCHHCEECCCCEEEEECCCCCEEEEEEEECCHHHHHCHHHHEECCCCCEEEEEEECC
GGFGGKEDVPSYVASYAAVAAYNTGRPAKLIYSREVDIQTTSKRHPITSHYKIGVDKSGK
CCCCCCCHHHHHHHHHHHHEEECCCCCEEEEEEECCCEEECCCCCCCCCCEEECCCCCCC
LKSIEIKAYMDMGAYATLSPIVMFRTLVHAAGSYEIPNVKVDVYGVYTNKVPPGAFRGFG
EEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHCCCC
SPQVLFAVESMIDEISLKLGIDPIEFRLKNTLRVGSRTATNHLLTESVGAVQTLENVRTI
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADWENLKKEVEEFNKQNSFKKRGLGVSHIIYGVSLGAAGQHLDASGAHIQVNKDGTIDVR
HHHHHHHHHHHHHHHHCCHHHHCCCHHHHHEEEEECCCCCCCCCCCCEEEECCCCEEEEE
IGGTEMGQGAKTVIAMLAAEELGQKLEKINVHQPDTAFVPDSGPTVASRTTLYSGNAVRI
ECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCEEEECCCEEEH
AARELRKRFVQLFAEIFDTDPEDVSWENGRYFDSKGNELSFDELVENAYMKNVKLNETGW
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHCCCEECCCCC
YETPKLEWDHETGQGEAYVTYSYASQIVLVEVDMLTGLTRVVKGFTSHDVGKALNPEGLI
CCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCE
GQIQGGFVQGMGYALYEQIKMDRGKIVTDNFNTYIIPTIHEIPEELKIDIVEDEYSSGPY
EEECCCHHHHHHHHHHHHHHCCCCEEEECCCCEEEECCHHHCCHHHEEEEEECCCCCCCC
GAKGIGEPSLMPTPAAIANGISRAIGKRVKRIPATAEYILKLIKEA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]