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The map label for this gene is ade

Identifier: 239618447

GI number: 239618447

Start: 2217863

End: 2219596

Strand: Reverse

Name: ade

Synonym: Kole_2088

Alternate gene names: 239618447

Gene position: 2219596-2217863 (Counterclockwise)

Preceding gene: 239618448

Following gene: 239618446

Centisome position: 96.42

GC content: 42.85

Gene sequence:

>1734_bases
GTGAACATAATAGACATAATTCCTGTTGCACGTGGGAAACAACCCGCTGATTTGTTGTTAAAAAATGCGCGAATAGTCAA
TGTGTTTAGTGGAGAAATCGAAAGGGCAAACATTGCCATTTTTCGTAAAAGAATCGCGGGGATAGGTGATTACTCTGAAG
GAAAACAGGTAATTGATTTGCACGGTGCATACGTTGTACCGGGATTAATAGACGCGCATCTTCACATTGAATCTTCCATG
GTTTCACCGGTGGAGTTTGCAAAAACGGTATTGCCGCGCGGAACTACTACTGTTATCGCTGATCCCCATGAAATCGCTAA
CGTTCTTGGACTCGATGGTGTAGAATACCTGATAAAATCCACTGAAGGAGTACCTCTCAATCTCTACATCATGCTCCCAT
CATCTGTACCTGCAACAAATCTGGAAAACAACGGTGCGAGGATCTCCGTCATGGATATGATAGGGTTCGTGGAGAAACAT
CCCCGGGTATTGGGTCTTGGCGAAGTGATGAATTATCCCGATATAATAAATGGAGATCATGATTCCATCGCCAAGATCGA
ACTTCTTCGCCACAAATACAAAAAAATTGACGGGCACATTCCGGGAATTTCGGGTAAGGATTTGAACGCCTATATCTGTG
CCTTCATCCGCTCTGACCACGAATGTACAAATGTGGAAGAGGCAAAAGAAAAGCTTGCTCGTGGGATGCAGATTCTTGTG
CGTGAAGGAAGTGTAGCGAGAAATCTCGATGAGCTTTTACCGTTAATCAACGAAAAGAATTATCCTTTTATATCTTTTTG
TACTGATGACAAACATCCGAATGATATTCTCAACGAAGGTCACATAGATTATATGATCAGATATGCCATAAAGAAGGGCA
TCGATCCGATAACCGCTGTGAGGGCTGCAACAATCAATACGGCACGCCATTATAATCTCAGATCAATGGGTGCGATAGCT
CCGGGATACAAAGCTGATTTCGTTATCGTTGATAATTTAGAAGAATTCAGGATCTCAATGGTCTTCAAAGATTCAAAACT
CATCGCTGAAAACGGTAAACTCGTTATAGATATAAACCGCGAACAGTTTCCGCTCGAAGAGGTCAATACCTTCAAGTGTC
CGCATATTGAAGAGAAGGATCTTGAGGTATTGAATAAAGGCGAAAATATACGTGTAATAAGGGTTTATGGAGATGATGTT
TTAACAAAAGAACTTAGAATGGAACCCAAAACGAAAGATGGACGGATAGTATCCGATGTCAATAGAGATATACTGAAAGT
CGCTTCCATATGCAGATATTGTGAAGAGAAATCAATGGCGATAGGGTTCATTAACGGAACAGGTTTAAAGCAGGGAGCCG
TCGCCACATCAGTGGGCCACGATGCCCACAATATGTCTGTGATAGGTACCAACGACGCTGATATGGTTGTGGCTGCAAAC
AGGGTAATCGATATGGGAGGTGGCCTTGTTATTGCAAATTCTGGAAAAGTTCTGGCAGAACTGCCCCTGCCCATCGCGGG
CTTAATGTCTAATCTCAGCTCGAAGGAGGTTGCAGAGCGCCTCGGACATTTGAAAACAGTGTTGAAAGAACTTGGATGTG
AGGTCCCGGATCTCTTTATGACCCTTTCTTTTGTTCAGCTTTCGGTGATACCGGAATTGAGAATAACAAATCAGGGGCTT
GTTGATGTTATCAACAATAACTTTGTATCACTGTTCATCGGAAAGGAAGGCTGA

Upstream 100 bases:

>100_bases
ATACAGGCTATAAGCAGCTCATTTCGGGCGTTATTAACGTTCCTTGCTTTTGTCATCCTTTGGCTTCATGTTTATAATCG
ACAAAAAAGGAGGGGCTACT

Downstream 100 bases:

>100_bases
CATTATGAGGACAACAGTAAAACTCAGGAACGTTATAGGAAAGAAAGTCAAAAGGGTTGATGCACTGCCTAAAGTAACCG
GGCAGGCTAAATTTGCAGCT

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MNIIDIIPVARGKQPADLLLKNARIVNVFSGEIERANIAIFRKRIAGIGDYSEGKQVIDLHGAYVVPGLIDAHLHIESSM
VSPVEFAKTVLPRGTTTVIADPHEIANVLGLDGVEYLIKSTEGVPLNLYIMLPSSVPATNLENNGARISVMDMIGFVEKH
PRVLGLGEVMNYPDIINGDHDSIAKIELLRHKYKKIDGHIPGISGKDLNAYICAFIRSDHECTNVEEAKEKLARGMQILV
REGSVARNLDELLPLINEKNYPFISFCTDDKHPNDILNEGHIDYMIRYAIKKGIDPITAVRAATINTARHYNLRSMGAIA
PGYKADFVIVDNLEEFRISMVFKDSKLIAENGKLVIDINREQFPLEEVNTFKCPHIEEKDLEVLNKGENIRVIRVYGDDV
LTKELRMEPKTKDGRIVSDVNRDILKVASICRYCEEKSMAIGFINGTGLKQGAVATSVGHDAHNMSVIGTNDADMVVAAN
RVIDMGGGLVIANSGKVLAELPLPIAGLMSNLSSKEVAERLGHLKTVLKELGCEVPDLFMTLSFVQLSVIPELRITNQGL
VDVINNNFVSLFIGKEG

Sequences:

>Translated_577_residues
MNIIDIIPVARGKQPADLLLKNARIVNVFSGEIERANIAIFRKRIAGIGDYSEGKQVIDLHGAYVVPGLIDAHLHIESSM
VSPVEFAKTVLPRGTTTVIADPHEIANVLGLDGVEYLIKSTEGVPLNLYIMLPSSVPATNLENNGARISVMDMIGFVEKH
PRVLGLGEVMNYPDIINGDHDSIAKIELLRHKYKKIDGHIPGISGKDLNAYICAFIRSDHECTNVEEAKEKLARGMQILV
REGSVARNLDELLPLINEKNYPFISFCTDDKHPNDILNEGHIDYMIRYAIKKGIDPITAVRAATINTARHYNLRSMGAIA
PGYKADFVIVDNLEEFRISMVFKDSKLIAENGKLVIDINREQFPLEEVNTFKCPHIEEKDLEVLNKGENIRVIRVYGDDV
LTKELRMEPKTKDGRIVSDVNRDILKVASICRYCEEKSMAIGFINGTGLKQGAVATSVGHDAHNMSVIGTNDADMVVAAN
RVIDMGGGLVIANSGKVLAELPLPIAGLMSNLSSKEVAERLGHLKTVLKELGCEVPDLFMTLSFVQLSVIPELRITNQGL
VDVINNNFVSLFIGKEG
>Mature_577_residues
MNIIDIIPVARGKQPADLLLKNARIVNVFSGEIERANIAIFRKRIAGIGDYSEGKQVIDLHGAYVVPGLIDAHLHIESSM
VSPVEFAKTVLPRGTTTVIADPHEIANVLGLDGVEYLIKSTEGVPLNLYIMLPSSVPATNLENNGARISVMDMIGFVEKH
PRVLGLGEVMNYPDIINGDHDSIAKIELLRHKYKKIDGHIPGISGKDLNAYICAFIRSDHECTNVEEAKEKLARGMQILV
REGSVARNLDELLPLINEKNYPFISFCTDDKHPNDILNEGHIDYMIRYAIKKGIDPITAVRAATINTARHYNLRSMGAIA
PGYKADFVIVDNLEEFRISMVFKDSKLIAENGKLVIDINREQFPLEEVNTFKCPHIEEKDLEVLNKGENIRVIRVYGDDV
LTKELRMEPKTKDGRIVSDVNRDILKVASICRYCEEKSMAIGFINGTGLKQGAVATSVGHDAHNMSVIGTNDADMVVAAN
RVIDMGGGLVIANSGKVLAELPLPIAGLMSNLSSKEVAERLGHLKTVLKELGCEVPDLFMTLSFVQLSVIPELRITNQGL
VDVINNNFVSLFIGKEG

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=574, Percent_Identity=38.8501742160279, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_KOSOT (C5CI63)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941769.1
- GeneID:   7968499
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_2088
- ProtClustDB:   CLSK2400509
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 63527; Mature: 63527

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIDIIPVARGKQPADLLLKNARIVNVFSGEIERANIAIFRKRIAGIGDYSEGKQVIDL
CCCEEEEECCCCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEE
HGAYVVPGLIDAHLHIESSMVSPVEFAKTVLPRGTTTVIADPHEIANVLGLDGVEYLIKS
CCCEECCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHCCCHHHHHHHC
TEGVPLNLYIMLPSSVPATNLENNGARISVMDMIGFVEKHPRVLGLGEVMNYPDIINGDH
CCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEHHHHCCCCCCCCCCC
DSIAKIELLRHKYKKIDGHIPGISGKDLNAYICAFIRSDHECTNVEEAKEKLARGMQILV
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEE
REGSVARNLDELLPLINEKNYPFISFCTDDKHPNDILNEGHIDYMIRYAIKKGIDPITAV
ECCCHHCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCHHHHHHHHHHHCCCHHHHH
RAATINTARHYNLRSMGAIAPGYKADFVIVDNLEEFRISMVFKDSKLIAENGKLVIDINR
HHHHCCHHHCCCCHHCCCCCCCCCCCEEEECCCCCEEEEEEEECCEEEECCCCEEEEECC
EQFPLEEVNTFKCPHIEEKDLEVLNKGENIRVIRVYGDDVLTKELRMEPKTKDGRIVSDV
CCCCHHHCCCCCCCCCCCCCHHHHCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCHHHH
NRDILKVASICRYCEEKSMAIGFINGTGLKQGAVATSVGHDAHNMSVIGTNDADMVVAAN
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCCEEEEEC
RVIDMGGGLVIANSGKVLAELPLPIAGLMSNLSSKEVAERLGHLKTVLKELGCEVPDLFM
EEEECCCCEEEECCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
TLSFVQLSVIPELRITNQGLVDVINNNFVSLFIGKEG
HHHHHHHEECCCEEECCCCHHEECCCCEEEEEEECCC
>Mature Secondary Structure
MNIIDIIPVARGKQPADLLLKNARIVNVFSGEIERANIAIFRKRIAGIGDYSEGKQVIDL
CCCEEEEECCCCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCEEEEE
HGAYVVPGLIDAHLHIESSMVSPVEFAKTVLPRGTTTVIADPHEIANVLGLDGVEYLIKS
CCCEECCCCEEEEEEECCCCCCHHHHHHHHCCCCCEEEEECHHHHHHHHCCCHHHHHHHC
TEGVPLNLYIMLPSSVPATNLENNGARISVMDMIGFVEKHPRVLGLGEVMNYPDIINGDH
CCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEHHHHCCCCCCCCCCC
DSIAKIELLRHKYKKIDGHIPGISGKDLNAYICAFIRSDHECTNVEEAKEKLARGMQILV
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEE
REGSVARNLDELLPLINEKNYPFISFCTDDKHPNDILNEGHIDYMIRYAIKKGIDPITAV
ECCCHHCCHHHHHHHHCCCCCCEEEEECCCCCCHHHHCCCCHHHHHHHHHHHCCCHHHHH
RAATINTARHYNLRSMGAIAPGYKADFVIVDNLEEFRISMVFKDSKLIAENGKLVIDINR
HHHHCCHHHCCCCHHCCCCCCCCCCCEEEECCCCCEEEEEEEECCEEEECCCCEEEEECC
EQFPLEEVNTFKCPHIEEKDLEVLNKGENIRVIRVYGDDVLTKELRMEPKTKDGRIVSDV
CCCCHHHCCCCCCCCCCCCCHHHHCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCHHHH
NRDILKVASICRYCEEKSMAIGFINGTGLKQGAVATSVGHDAHNMSVIGTNDADMVVAAN
HHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCCEEEEEC
RVIDMGGGLVIANSGKVLAELPLPIAGLMSNLSSKEVAERLGHLKTVLKELGCEVPDLFM
EEEECCCCEEEECCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
TLSFVQLSVIPELRITNQGLVDVINNNFVSLFIGKEG
HHHHHHHEECCCEEECCCCHHEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA